Page last updated: 2024-08-17

ethinyl estradiol and theophylline

ethinyl estradiol has been researched along with theophylline in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Delaforge, M; Sartori, E1
Chin, TF; Correia, J; Koren, G; MacLeod, SM; Tesoro, A1
Friedman, S; Golan, A; Goldman, J; Shoenfeld, A1
Gardner, MJ; Jusko, WJ; Kanarkowski, R; Tornatore, KM1
Gardner, MJ; Jusko, WJ; Kanarkowski, R; McCarthy, TL; Tornatore, KM; Yurchak, AM1
Backman, JT; Granfors, MT; Laitila, J; Neuvonen, PJ1

Trials

1 trial(s) available for ethinyl estradiol and theophylline

ArticleYear
Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:4

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Area Under Curve; Caffeine; Clonidine; Contraceptives, Oral, Combined; Cytochrome P-450 CYP1A2 Inhibitors; Drug Synergism; Ethinyl Estradiol; Female; Half-Life; Humans; Norpregnenes; Theophylline

2005

Other Studies

15 other study(ies) available for ethinyl estradiol and theophylline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Specific drug binding to rat liver cytochrome P-450 isozymes induced by pregnenolone-16 alpha-carbonitrile and macrolide antibiotics. Implications for drug interactions.
    Chemico-biological interactions, 1990, Volume: 73, Issue:2-3

    Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Enzyme Induction; Ergotamine; Ergotamines; Erythromycin; Ethinyl Estradiol; Ethylmorphine; Ferricyanides; Isoenzymes; Male; Microsomes, Liver; Norethindrone; Prednisolone; Prednisone; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Spectrophotometry; Theophylline

1990
Theophylline pharmacokinetics in adolescent females following coadministration of oral contraceptives.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1985, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Contraceptives, Oral, Combined; Ethinyl Estradiol; Female; Humans; Kinetics; Norethindrone; Theophylline

1985
Acute opthalmologic complications during the use of oral contraceptives.
    Contraception, 1974, Volume: 10, Issue:6

    Topics: Adult; Amino Alcohols; Arterial Occlusive Diseases; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Drug Combinations; Ethinyl Estradiol; Ethynodiol Diacetate; Female; Humans; Mestranol; Nicotinic Acids; Norethindrone; Retinal Artery; Theophylline; Vision Disorders; Warfarin

1974
Effects of tobacco smoking and oral contraceptive use on theophylline disposition.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:3

    Topics: Adult; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Ethinyl Estradiol; Female; Humans; Kinetics; Norgestrel; Smoking; Theophylline

1983
Effect of chronic oral contraceptive steroids on theophylline disposition.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:2

    Topics: Adult; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Ethinyl Estradiol; Humans; Male; Theophylline; Time Factors

1982