Page last updated: 2024-08-17

ethinyl estradiol and rifampin

ethinyl estradiol has been researched along with rifampin in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (46.88)	18.7374
1990's	3 (9.38)	18.2507
2000's	5 (15.63)	29.6817
2010's	7 (21.88)	24.3611
2020's	2 (6.25)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bolt, HM; Bolt, M; Kappus, H	3
Challiner, MR; Park, BK; Whittaker, AD	1
Gelbke, HP; Gethmann, U; Knuppen, R	1
Chaline, G; Muglioni, JF; Piguet, B	1
Shenfield, GM	1
Anklesaria, PS; Gupta, KC; Joshi, JV; Satoskar, RS; Shah, RS	1
Altschuler, SL; Valenteen, JW	1
Breuer, H; Nocke-Finck, L; Reimers, D	1
Back, DJ; Breckenridge, AM; Crawford, F; Cross, K; MacIver, M; Orme, ML; Rowe, PH; Smith, E	1
Orme, ML	1
Back, DJ; Barkfeldt, JO; Breckenridge, AM; Odlind, V; Orme, M; Park, BK; Purba, H; Tjia, J; Victor, A	1
Back, DJ; Breckenridge, AM; Crawford, FE; Hall, JM; MacIver, M; Orme, ML; Rowe, PH; Smith, E; Watts, MJ	1
Allard, S; Colborn, D; Guilbert, E; LeBel, M; Masson, E; Narang, PK; Paquet, F; Vallée, F	1
Barditch-Crovo, P; Coresh, J; Ette, E; Flexner, C; Hendrix, CW; Rocco, LE; Trapnell, CB; Zacur, HA	1
Min, G	1
Brudny-Klöppel, M; Fricke, R; Friedrich, C; Gashaw, I; Höchel, J; Klein, S; Nowotny, B; Riecke, K; Rottmann, A; Wiesinger, H	1
Chaturvedula, A; Cicali, B; Cristofoletti, R; Hoechel, J; Lingineni, K; Schmidt, S; Vozmediano, V; Wendl, T; Wiesinger, H	1

Reviews

3 review(s) available for ethinyl estradiol and rifampin

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Drug interactions with oral contraceptive preparations. The Medical journal of Australia, 1986, Feb-17, Volume: 144, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Analgesics; Anti-Anxiety Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Benzodiazepines; Contraceptives, Oral; Cyclosporins; Drug Interactions; Enterohepatic Circulation; Ethanol; Ethinyl Estradiol; Female; Griseofulvin; Humans; Intestinal Absorption; Protein Binding; Rifampin	1986
The third S.K. & F. Prize lecture, University of London, December 1981. The clinical pharmacology of oral contraceptive steroids. British journal of clinical pharmacology, 1982, Volume: 14, Issue:1 Topics: Administration, Oral; Anti-Bacterial Agents; Anticonvulsants; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Ethinyl Estradiol; Female; Humans; Injections, Intravenous; Intestinal Absorption; Kinetics; Protein Binding; Rifampin; Time Factors	1982

Trials

4 trial(s) available for ethinyl estradiol and rifampin

Article	Year
[Effects of rifampicin on the menstrual cycle and on oestrogen excretion in patients taking oral contraceptives]. Deutsche medizinische Wochenschrift (1946), 1973, Aug-11, Volume: 98, Issue:33 Topics: Adolescent; Adult; Clinical Trials as Topic; Contraceptives, Oral; Estriol; Estrogens; Estrone; Ethambutol; Ethinyl Estradiol; Female; Humans; Isoniazid; Menstruation Disturbances; Pregnancy; Rifampin; Streptomycin; Tuberculosis, Pulmonary	1973
Effects of rifabutin and rifampicin on the pharmacokinetics of ethinylestradiol and norethindrone. Journal of clinical pharmacology, 1998, Volume: 38, Issue:11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Contraceptives, Oral, Synthetic; Cross-Over Studies; Ethinyl Estradiol; Female; Fever; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Middle Aged; Neutropenia; Norethindrone; Rifabutin; Rifampin	1998
The effects of rifampin and rifabutin on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive. Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:4 Topics: Adult; Antibiotics, Antitubercular; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Enzyme Inhibitors; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; gamma-Glutamyltransferase; Humans; Luteinizing Hormone; Mixed Function Oxygenases; Norethindrone; Prospective Studies; Rifabutin; Rifampin	1999
The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam. Clinical pharmacology and therapeutics, 2020, Volume: 108, Issue:4 Topics: Aged; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Ethinyl Estradiol; Female; Germany; Humans; Midazolam; Middle Aged; Patient Safety; Progestins; Protein Binding; Rifampin; Risk Assessment; Sex Hormone-Binding Globulin	2020

Other Studies

25 other study(ies) available for ethinyl estradiol and rifampin

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Interaction of rifampicin treatment with pharmacokinetics and metabolism of ethinyloestradiol in man. Acta endocrinologica, 1977, Volume: 85, Issue:1 Topics: Administration, Oral; Adult; Ethinyl Estradiol; Female; Half-Life; Humans; Hydroxylation; Injections, Intravenous; Male; Rifampin	1977
The effect of enzyme induction on the irreversible binding of ethynyloestradiol to guinea pig liver microsomes. Life sciences, 1978, Dec-18, Volume: 23, Issue:25 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Ethinyl Estradiol; Flavonoids; Guinea Pigs; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rifampin; Spironolactone	1978
Influence of rifampicin treatment on the metabolic fate of [4-14C] mestranol in women. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1977, Volume: 9, Issue:5 Topics: Adult; Ethinyl Estradiol; Female; Humans; Hysterectomy; Mestranol; Rifampin	1977
[Letter: Oral contraception and rifampicin]. La Nouvelle presse medicale, 1975, Jan-11, Volume: 04, Issue:2 Topics: Adult; Drug Antagonism; Ethinyl Estradiol; Female; Humans; Microsomes, Liver; Norgestrel; Pregnancy; Rifampin; Tuberculosis, Cutaneous	1975
Effect of rifampicin treatment on the metabolism of oestradiol and 17alpha-ethinyloestradiol by human liver microsomes. European journal of clinical pharmacology, 1975, Jun-13, Volume: 8, Issue:5 Topics: Adult; Aged; Anisoles; Cytochrome P-450 Enzyme System; Enzyme Induction; Estradiol; Ethinyl Estradiol; Female; Humans; Hydroxylation; Male; Microsomes, Liver; Oxidation-Reduction; Protein Binding; Rifampin	1975
Plasma rifampicin levels during oral contraception. The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:6 Topics: Contraceptives, Oral, Combined; Ethinyl Estradiol; Female; Humans; Norethindrone; Norethindrone Acetate; Rifampin	1988
Letter: Rifampicin and oral contraception. Lancet (London, England), 1974, Jun-22, Volume: 1, Issue:7869 Topics: Biotransformation; Contraceptives, Oral; Drug Antagonism; Ethinyl Estradiol; Female; Humans; Liver; Rifampin	1974
Amenorrhea following rifampin administration during oral contraceptive use. Obstetrics and gynecology, 1974, Volume: 44, Issue:5 Topics: Adult; Amenorrhea; Contraceptives, Oral; Ethinyl Estradiol; Female; Humans; Norethindrone; Rifampin; Tuberculosis, Pulmonary	1974
Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids. Ciba Foundation symposium, 1980, Volume: 76 Topics: Animals; Antipyrine; Contraceptives, Oral; Environment; Ethinyl Estradiol; Female; Half-Life; Humans; Intestinal Mucosa; Jejunum; Kinetics; Norethindrone; Norgestrel; Phenobarbital; Rats; Rifampin	1980
The enzyme inducing effect of rifampicin in the rhesus monkey and its lack of interaction with oral contraceptive steroids. Contraception, 1982, Volume: 25, Issue:3 Topics: Animals; Antipyrine; Drug Interactions; Enzyme Induction; Ethinyl Estradiol; Female; Hydroxycholesterols; Macaca mulatta; Metabolic Clearance Rate; Microsomes, Liver; Norethindrone; Rifampin	1982
The effect of rifampicin on the pharmacokinetics of ethynylestradiol in women. Contraception, 1980, Volume: 21, Issue:2 Topics: Adolescent; Adult; Ethambutol; Ethinyl Estradiol; Female; Humans; Isoniazid; Kinetics; Norethindrone; Norethindrone Acetate; Rifampin; Sex Hormone-Binding Globulin; Tuberculosis	1980
Drug interaction with oral contraceptive steroids. British medical journal, 1980, Jul-12, Volume: 281, Issue:6233 Topics: Anti-Bacterial Agents; Anticonvulsants; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Ethinyl Estradiol; Female; Humans; Pregnancy; Rifampin	1980
From the Clinical Effectiveness Committee. Use of rifampicin and contraceptive steroids. The British journal of family planning, 1999, Volume: 24, Issue:4 Topics: Contraceptives, Oral, Hormonal; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Rifampin	1999
Antibiotic interference with oral contraceptives. Journal of the American Dental Association (1939), 2002, Volume: 133, Issue:7 Topics: Adult; Anti-Bacterial Agents; Contraceptives, Oral, Hormonal; Drug Antagonism; Ethinyl Estradiol; Female; Humans; Rifampin	2002
Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells. Experimental & molecular medicine, 2010, Nov-30, Volume: 42, Issue:11 Topics: Constitutive Androstane Receptor; Corticosterone; Estrogens; Ethinyl Estradiol; Hep G2 Cells; Humans; Liver; Liver X Receptors; Orphan Nuclear Receptors; Phenobarbital; Pregnane X Receptor; Pyridines; Receptor Cross-Talk; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Response Elements; Rifampin; Transcriptional Activation	2010
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling. CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:1 Topics: Adult; Alkynes; Benzoxazines; Body Mass Index; Carbamazepine; Clarithromycin; Computer Simulation; Contraceptives, Oral, Combined; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Humans; Itraconazole; Levonorgestrel; Models, Biological; Obesity; Rifampin; Sex Hormone-Binding Globulin	2021