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ethinyl estradiol and raloxifene hydrochloride

ethinyl estradiol has been researched along with raloxifene hydrochloride in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's9 (36.00)18.2507
2000's8 (32.00)29.6817
2010's7 (28.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Veldhuis, JD1
Bryant, HU; Cole, HW; Draper, MW; Fuchs-Young, R; Glasebrook, AL; Magee, DE; Rippy, MK; Short, LL; Termine, JD1
Draper, MW; Flowers, DE; Huster, WJ; Neild, JA; Zerbe, RL1
Bryant, HU; Kim, J; Sato, M; Short, LL; Slemenda, CW1
Bryant, HU; Sato, M; Turner, CH1
Bekele, A; Bendele, R; Bensch, WR; Black, LJ; Cullinan, GJ; Kauffman, RF; Magee, DE; Rowley, ER; Sato, M; Williams, DC1
Bryant, HU; Evans, GL; Magee, DE; Turner, RT1
Carver, JM; Lundeen, SG; McKean, ML; Winneker, RC1
Cheskis, BJ; Karathanasis, S; Lyttle, CR1
Andersson-Ross, C; Barkhem, T; Höglund, M; Nilsson, S1
Bean, JS; Bensch, WR; Cox, DA; Cullinan, GJ; Fahey, KJ; Kauffman, RF1
Bayraktar, F; Oge, A; Ozgönül, M; Sezer, ED; Sözmen, EY2
Bryant, HU; Cole, HW; Hoover, J; Jee, WS; Ma, YL; Sato, M; Schmidt, A; Yao, W; Zeng, Q1
Armamento-Villareal, R; Brodt, MD; Caruso, PL; Civelli, M; Civitelli, R; Galbiati, E; Halstead, LR; Mueller, C; Napoli, N; Nawaz, A; Sheikh, S; Silva, MJ1
Birkenes, B; Dahm, AE; Iversen, N; Ree, AH; Sandset, PM1
Brown, KH; Cline, JM; Hutchison, J; Lees, CJ; Lundeen, S; Register, TC; Sikoski, P1
Kluft, C1
Boudot, A; Flouriot, G; Habauzit, D; Kerdivel, G; Pakdel, F1
Adamo, EB; Altavilla, D; Bitto, A; Calò, M; Irrera, N; Marini, H; Minutoli, L; Polito, F; Squadrito, F; Vaccaro, M1
Cavileer, TD; Nagler, JJ; Shyu, C; Ytreberg, FM1
Adamo, EB; Altavilla, D; Bitto, A; Irrera, N; Marini, H; Micali, A; Minutoli, L; Polito, F; Squadrito, F; Vaccaro, M1
Endo, S; Fukami, T; Higuchi, S; Miyashita, T; Nakajima, M; Toyoda, Y; Tsukui, T; Tsuneyama, K; Yokoi, T; Yoshikawa, Y1
Kari, S; Lammintausta, R; Unkila, M; Yatkin, E1
Bloom, RA; Laurenson, JP; Pinto, CL1

Reviews

1 review(s) available for ethinyl estradiol and raloxifene hydrochloride

ArticleYear
Effects of hormone treatment on hemostasis variables.
    Climacteric : the journal of the International Menopause Society, 2007, Volume: 10 Suppl 2

    Topics: Administration, Oral; Administration, Topical; Dose-Response Relationship, Drug; Estrogen Receptor Modulators; Estrogen Replacement Therapy; Ethinyl Estradiol; Female; Hemostasis; Humans; Inflammation; Norpregnenes; Progestins; Raloxifene Hydrochloride; Tamoxifen; Venous Thromboembolism

2007

Trials

2 trial(s) available for ethinyl estradiol and raloxifene hydrochloride

ArticleYear
Antiestrogenic properties of raloxifene.
    Pharmacology, 1995, Volume: 50, Issue:4

    Topics: Adult; Analysis of Variance; Drug Interactions; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Luteinizing Hormone; Male; Middle Aged; Piperidines; Pituitary Hormones, Anterior; Prolactin; Raloxifene Hydrochloride; Sex Hormone-Binding Globulin; Tamoxifen; Testosterone; Transcortin

1995
Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopause.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 138

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Ethinyl Estradiol; Female; Humans; Menopause; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen; Vagina; Vaginal Diseases; Vulva

2013

Other Studies

22 other study(ies) available for ethinyl estradiol and raloxifene hydrochloride

ArticleYear
Mechanisms subserving the bipotential actions of estrogen on ovarian cells: studies with a selective anti-estrogen, LY156758, and the sparingly metabolizable estrogen agonist, moxestrol.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Dose-Response Relationship, Drug; Estradiol; Ethinyl Estradiol; Female; Ovary; Piperidines; Pregnenolone; Progesterone; Raloxifene Hydrochloride; Receptors, Estradiol; Swine

1986
Raloxifene is a tissue-selective agonist/antagonist that functions through the estrogen receptor.
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Animals; Bone Density; Breast Neoplasms; Cell Division; Cholesterol; Ethinyl Estradiol; Female; Humans; Middle Aged; Organ Size; Organ Specificity; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured; Uterus

1995
Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Aging; Animals; Bone Density; Ethinyl Estradiol; Female; Lipids; Organ Size; Osteoporosis; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Tomography, X-Ray Computed; Uterus

1995
Raloxifene preserves bone strength and bone mass in ovariectomized rats.
    Endocrinology, 1994, Volume: 135, Issue:5

    Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Densitometry; Estrogens; Ethinyl Estradiol; Female; Femur Neck; Lumbar Vertebrae; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Time Factors; Uterus

1994
Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Administration, Oral; Alkaline Phosphatase; Animals; Body Weight; Bone Density; Bone Resorption; Calcium; Cholesterol; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Estrogen Antagonists; Ethinyl Estradiol; Female; Hypertrophy; Ovariectomy; Phosphorus; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Triglycerides; Uterus

1994
Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia.
    Endocrinology, 1996, Volume: 137, Issue:10

    Topics: Animals; Bone and Bones; Bone Diseases, Metabolic; Dose-Response Relationship, Drug; Estrogen Antagonists; Ethinyl Estradiol; Female; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley

1996
Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels.
    Endocrinology, 1997, Volume: 138, Issue:4

    Topics: Animals; Cholesterol; Dexamethasone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Lipids; Ovariectomy; Piperidines; Progesterone; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1997
Estrogen receptor ligands modulate its interaction with DNA.
    The Journal of biological chemistry, 1997, Apr-25, Volume: 272, Issue:17

    Topics: DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Fulvestrant; Humans; Ligands; Piperidines; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Tamoxifen; Transcription Factors

1997
Characterization of the "estrogenicity" of tamoxifen and raloxifene in HepG2 cells: regulation of gene expression from an ERE controlled reporter vector versus regulation of the endogenous SHBG and PS2 genes.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 62, Issue:1

    Topics: Alkaline Phosphatase; Carcinoma, Hepatocellular; Clone Cells; Estradiol; Estradiol Congeners; Estrogen Antagonists; Ethinyl Estradiol; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Kinetics; Liver Neoplasms; Piperidines; Placenta; Pregnancy; Protein Biosynthesis; Proteins; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Sex Hormone-Binding Globulin; Tamoxifen; Tetradecanoylphorbol Acetate; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1997
Raloxifene and estrogen inhibit neointimal thickening after balloon injury in the carotid artery of male and ovariectomized female rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:4

    Topics: Animals; Carotid Artery Injuries; Catheterization; Cholesterol; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Fulvestrant; Male; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley

2000
The effects of estrogen and raloxifene treatment on the antioxidant enzymes and nitrite-nitrate levels in brain cortex of ovariectomized rats.
    Neuroscience letters, 2003, Mar-06, Volume: 338, Issue:3

    Topics: Animals; Catalase; Cerebral Cortex; Ethinyl Estradiol; Female; Nitrates; Nitric Oxide; Nitrites; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Superoxide Dismutase

2003
New bone formation with teriparatide [human parathyroid hormone-(1-34)] is not retarded by long-term pretreatment with alendronate, estrogen, or raloxifene in ovariectomized rats.
    Endocrinology, 2003, Volume: 144, Issue:5

    Topics: Alendronate; Animals; Biomechanical Phenomena; Bone Density; Bone Resorption; Drug Administration Schedule; Ethinyl Estradiol; Female; Femur; Osteogenesis; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Spine; Tensile Strength; Teriparatide; Tibia; Time Factors

2003
The effects of estrogen and raloxifene treatment on antioxidant enzymes in brain and liver of ovarectomized female rats.
    Endocrine research, 2003, Volume: 29, Issue:2

    Topics: Analysis of Variance; Animals; Antioxidants; Brain; Catalase; Estrogens; Ethinyl Estradiol; Female; In Vitro Techniques; Liver; Ovariectomy; Oxidoreductases; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Superoxide Dismutase

2003
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Absorptiometry, Photon; Amino Acids; Animals; Benzopyrans; Biomechanical Phenomena; Blood; Body Composition; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Cholesterol; Compressive Strength; Estrogen Receptor Modulators; Ethinyl Estradiol; Female; Femur; Femur Neck; Lumbar Vertebrae; Organ Size; Osteoclasts; Osteogenesis; Ovariectomy; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Tibia; Tomography, X-Ray Computed; Triglycerides; Uterus; Weight-Bearing

2005
Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1.
    BMC cardiovascular disorders, 2006, Oct-09, Volume: 6

    Topics: Cells, Cultured; Down-Regulation; Endothelial Cells; Estradiol; Estrogen Receptor alpha; Ethinyl Estradiol; Fulvestrant; Humans; Lipoproteins; Raloxifene Hydrochloride; RNA, Messenger; Selective Estrogen Receptor Modulators

2006
Effects of two novel selective estrogen receptor modulators, raloxifene, tamoxifen, and ethinyl estradiol on the uterus, vagina and breast in ovariectomized cynomolgus monkeys (Macaca fascicularis).
    American journal of obstetrics and gynecology, 2007, Volume: 196, Issue:1

    Topics: Animals; Estrogens; Ethinyl Estradiol; Female; Macaca fascicularis; Mammary Glands, Animal; Ovariectomy; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Uterus; Vagina

2007
Development and validation of a test for environmental estrogens: Checking xeno-estrogen activity by CXCL12 secretion in BREAST CANCER CELL LINES (CXCL-test).
    Environmental toxicology, 2010, Volume: 25, Issue:5

    Topics: Benzhydryl Compounds; Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Dose-Response Relationship, Drug; Environmental Monitoring; Environmental Pollutants; Estradiol; Estrogen Receptor Modulators; Estrogens; Ethinyl Estradiol; Female; Genistein; Humans; Phenols; Raloxifene Hydrochloride; Tamoxifen; Time Factors

2010
Genistein aglycone improves skin repair in an incisional model of wound healing: a comparison with raloxifene and oestradiol in ovariectomized rats.
    British journal of pharmacology, 2010, Volume: 160, Issue:5

    Topics: Animals; Dermatologic Surgical Procedures; Disease Models, Animal; Dose-Response Relationship, Drug; Ethinyl Estradiol; Female; Genistein; GTP-Binding Proteins; Ovariectomy; Phytoestrogens; Protein Glutamine gamma Glutamyltransferase 2; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Sprague-Dawley; Skin; Tensile Strength; Transforming Growth Factor beta1; Transglutaminases; Vascular Endothelial Growth Factor A; Wound Healing

2010
Computational estimation of rainbow trout estrogen receptor binding affinities for environmental estrogens.
    Toxicology and applied pharmacology, 2011, Feb-01, Volume: 250, Issue:3

    Topics: Animals; Atrazine; Benzhydryl Compounds; Computational Biology; Endocrine Disruptors; Environmental Pollutants; Estradiol Congeners; Ethinyl Estradiol; Humans; In Vitro Techniques; Oncorhynchus mykiss; Phenols; Protein Isoforms; Raloxifene Hydrochloride; Receptors, Estrogen; Testosterone

2011
Genistein aglycone, a soy-derived isoflavone, improves skin changes induced by ovariectomy in rats.
    British journal of pharmacology, 2012, Volume: 165, Issue:4

    Topics: Animals; Ethinyl Estradiol; Female; Genistein; Glycine max; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Animal; Ovariectomy; Phytoestrogens; Postmenopause; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Skin Aging; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2012
Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries.
    Toxicology and applied pharmacology, 2012, Oct-01, Volume: 264, Issue:1

    Topics: Animals; Cell Differentiation; Chemical and Drug Induced Liver Injury; Estrogen Receptor alpha; Ethinyl Estradiol; Female; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Raloxifene Hydrochloride; RNA, Messenger; RNA, Small Interfering; Selective Estrogen Receptor Modulators; Tamoxifen; Up-Regulation

2012
An Approach for Using In Vitro and In Silico Data to Identify Pharmaceuticals with Potential (Anti-)Estrogenic Activity in Aquatic Vertebrates at Environmentally Relevant Concentrations.
    Environmental toxicology and chemistry, 2019, Volume: 38, Issue:10

    Topics: Animals; Biological Assay; Environmental Exposure; Estradiol; Estrogens; Ethinyl Estradiol; Fishes; Indoles; Pharmaceutical Preparations; Raloxifene Hydrochloride; Receptors, Estrogen

2019