Page last updated: 2024-08-17

ethinyl estradiol and piperidines

ethinyl estradiol has been researched along with piperidines in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's9 (47.37)18.2507
2000's5 (26.32)29.6817
2010's2 (10.53)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Veldhuis, JD1
Bryant, HU; Cole, HW; Draper, MW; Fuchs-Young, R; Glasebrook, AL; Magee, DE; Rippy, MK; Short, LL; Termine, JD1
Draper, MW; Flowers, DE; Huster, WJ; Neild, JA; Zerbe, RL1
Bryant, HU; Kim, J; Sato, M; Short, LL; Slemenda, CW1
Bryant, HU; Sato, M; Turner, CH1
Bekele, A; Bendele, R; Bensch, WR; Black, LJ; Cullinan, GJ; Kauffman, RF; Magee, DE; Rowley, ER; Sato, M; Williams, DC1
Bryant, HU; Evans, GL; Magee, DE; Turner, RT1
Carver, JM; Lundeen, SG; McKean, ML; Winneker, RC1
Cheskis, BJ; Karathanasis, S; Lyttle, CR1
Andersson-Ross, C; Barkhem, T; Höglund, M; Nilsson, S1
Bryant, HU; Burris, LL; Glasebrook, AL; Palkowitz, AD; Pearce, HL; Peer, C; Sporn, MB; Starling, JJ; Suh, N; Wang, Y; Williams, C1
Amari, G; Armani, E; Caruso, PL; Civelli, M; Delcanale, M; Galbiati, E; Ghirardi, S1
Arshad, M; Ghosh, R; Sawlani, V; Sengupta, S; Sharma, S; Singh, MM1
Adrian, MD; Bryant, HU; Cohen, IR; Dodge, JA; Donnelly, KB; Draper, MW; Geiser, AG; Henck, JW; Hummel, CW; McCann, DJ; Oldham, SW; Rudmann, DG; Sato, M; Shepherd, TA; Wallace, OB1
Armamento-Villareal, R; Brodt, MD; Caruso, PL; Civelli, M; Civitelli, R; Galbiati, E; Halstead, LR; Mueller, C; Napoli, N; Nawaz, A; Sheikh, S; Silva, MJ1
Mayer, GD; Notch, EG1
Alvey, CW; Krishnaswami, S; Menon, S; Petit, W; Riese, R; Shi, H; Wang, R1
Cordoba, R; de Jong, J; Dlugosz-Danecka, M; Hellemans, P; Jiao, J; Jurczak, W; Mitselos, A; Ouellet, D; Panizo, C; Sukbuntherng, J; Wrobel, T1
Fukuda, K; Ieda, M; Kurokawa, J; Sakamoto, K; Sugimoto, M; Sugimoto, S; Suzuki, T; Tamura, F; Yamaguchi, M1

Trials

3 trial(s) available for ethinyl estradiol and piperidines

ArticleYear
Antiestrogenic properties of raloxifene.
    Pharmacology, 1995, Volume: 50, Issue:4

    Topics: Adult; Analysis of Variance; Drug Interactions; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Luteinizing Hormone; Male; Middle Aged; Piperidines; Pituitary Hormones, Anterior; Prolactin; Raloxifene Hydrochloride; Sex Hormone-Binding Globulin; Tamoxifen; Testosterone; Transcortin

1995
Evaluation of the Effect of Tofacitinib on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Volunteers.
    Clinical pharmacology in drug development, 2016, Volume: 5, Issue:5

    Topics: Adult; Area Under Curve; Contraceptives, Oral, Combined; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Half-Life; Humans; Levonorgestrel; Middle Aged; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Young Adult

2016
Ibrutinib does not have clinically relevant interactions with oral contraceptives or substrates of CYP3A and CYP2B6.
    Pharmacology research & perspectives, 2020, Volume: 8, Issue:5

    Topics: Adenine; Administration, Oral; Adult; Aged; Aged, 80 and over; Area Under Curve; Bupropion; Contraceptives, Oral; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Drug Interactions; Ethinyl Estradiol; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Levonorgestrel; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Metabolic Clearance Rate; Midazolam; Middle Aged; Piperidines; Waldenstrom Macroglobulinemia

2020

Other Studies

16 other study(ies) available for ethinyl estradiol and piperidines

ArticleYear
Mechanisms subserving the bipotential actions of estrogen on ovarian cells: studies with a selective anti-estrogen, LY156758, and the sparingly metabolizable estrogen agonist, moxestrol.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Dose-Response Relationship, Drug; Estradiol; Ethinyl Estradiol; Female; Ovary; Piperidines; Pregnenolone; Progesterone; Raloxifene Hydrochloride; Receptors, Estradiol; Swine

1986
Raloxifene is a tissue-selective agonist/antagonist that functions through the estrogen receptor.
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Animals; Bone Density; Breast Neoplasms; Cell Division; Cholesterol; Ethinyl Estradiol; Female; Humans; Middle Aged; Organ Size; Organ Specificity; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured; Uterus

1995
Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Aging; Animals; Bone Density; Ethinyl Estradiol; Female; Lipids; Organ Size; Osteoporosis; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Tomography, X-Ray Computed; Uterus

1995
Raloxifene preserves bone strength and bone mass in ovariectomized rats.
    Endocrinology, 1994, Volume: 135, Issue:5

    Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Densitometry; Estrogens; Ethinyl Estradiol; Female; Femur Neck; Lumbar Vertebrae; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Time Factors; Uterus

1994
Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Administration, Oral; Alkaline Phosphatase; Animals; Body Weight; Bone Density; Bone Resorption; Calcium; Cholesterol; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Estrogen Antagonists; Ethinyl Estradiol; Female; Hypertrophy; Ovariectomy; Phosphorus; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Triglycerides; Uterus

1994
Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia.
    Endocrinology, 1996, Volume: 137, Issue:10

    Topics: Animals; Bone and Bones; Bone Diseases, Metabolic; Dose-Response Relationship, Drug; Estrogen Antagonists; Ethinyl Estradiol; Female; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley

1996
Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels.
    Endocrinology, 1997, Volume: 138, Issue:4

    Topics: Animals; Cholesterol; Dexamethasone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Lipids; Ovariectomy; Piperidines; Progesterone; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1997
Estrogen receptor ligands modulate its interaction with DNA.
    The Journal of biological chemistry, 1997, Apr-25, Volume: 272, Issue:17

    Topics: DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Fulvestrant; Humans; Ligands; Piperidines; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Tamoxifen; Transcription Factors

1997
Characterization of the "estrogenicity" of tamoxifen and raloxifene in HepG2 cells: regulation of gene expression from an ERE controlled reporter vector versus regulation of the endogenous SHBG and PS2 genes.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 62, Issue:1

    Topics: Alkaline Phosphatase; Carcinoma, Hepatocellular; Clone Cells; Estradiol; Estradiol Congeners; Estrogen Antagonists; Ethinyl Estradiol; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Kinetics; Liver Neoplasms; Piperidines; Placenta; Pregnancy; Protein Biosynthesis; Proteins; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Sex Hormone-Binding Globulin; Tamoxifen; Tetradecanoylphorbol Acetate; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1997
Arzoxifene, a new selective estrogen receptor modulator for chemoprevention of experimental breast cancer.
    Cancer research, 2001, Dec-01, Volume: 61, Issue:23

    Topics: Animals; Anticarcinogenic Agents; Binding, Competitive; Cell Division; Drug Interactions; Estradiol; Estradiol Congeners; Estrogen Antagonists; Ethinyl Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Piperidines; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Tumor Cells, Cultured; Uterus

2001
Effects of 3-phenyl-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]- 2H-1-benzopyran-7-ol (CHF 4056), a novel nonsteroidal estrogen agonist/antagonist, on reproductive and nonreproductive tissue.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Animals; Benzopyrans; Bone Density; Cholesterol; Dose-Response Relationship, Drug; Eosinophil Peroxidase; Estradiol Congeners; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Ethinyl Estradiol; Female; Humans; In Vitro Techniques; Ovariectomy; Peroxidases; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Uterus

2002
In vitro anti-resorptive activity and prevention of ovariectomy-induced osteoporosis in female Sprague-Dawley rats by ormeloxifene, a selective estrogen receptor modulator.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 91, Issue:1-2

    Topics: Animals; Autopsy; Benzopyrans; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Calcium; Centchroman; Chick Embryo; Densitometry; Disease Models, Animal; Epithelial Cells; Ethinyl Estradiol; Female; Femur; Osteocalcin; Osteoporosis; Ovary; Parathyroid Hormone; Piperidines; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen; Tibia

2004
A new selective estrogen receptor modulator with potent uterine antagonist activity, agonist activity in bone, and minimal ovarian stimulation.
    Endocrinology, 2005, Volume: 146, Issue:10

    Topics: Animals; Bone and Bones; Cell Line, Tumor; Ethinyl Estradiol; Female; Humans; Kinetics; Naphthalenes; Ovariectomy; Ovulation Induction; Piperidines; Rats; Receptors, Estrogen; Sexual Maturation; Uterus

2005
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Absorptiometry, Photon; Amino Acids; Animals; Benzopyrans; Biomechanical Phenomena; Blood; Body Composition; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Cholesterol; Compressive Strength; Estrogen Receptor Modulators; Ethinyl Estradiol; Female; Femur; Femur Neck; Lumbar Vertebrae; Organ Size; Osteoclasts; Osteogenesis; Ovariectomy; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Tibia; Tomography, X-Ray Computed; Triglycerides; Uterus; Weight-Bearing

2005
Efficacy of pharmacological estrogen receptor antagonists in blocking activation of zebrafish estrogen receptors.
    General and comparative endocrinology, 2011, Aug-01, Volume: 173, Issue:1

    Topics: Animals; Cell Line, Tumor; Estradiol; Ethinyl Estradiol; Fulvestrant; Humans; Piperidines; Pyrazoles; Pyrimidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Zebrafish

2011
The Effect of a Synthetic Estrogen, Ethinylestradiol, on the hERG Block by E-4031.
    Biomolecules, 2021, 09-20, Volume: 11, Issue:9

    Topics: Estradiol Congeners; Ether-A-Go-Go Potassium Channels; Ethinyl Estradiol; HEK293 Cells; Humans; Ion Channel Gating; Piperidines; Pyridines

2021