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ethinyl estradiol and phenobarbital

ethinyl estradiol has been researched along with phenobarbital in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199035 (70.00)18.7374
1990's4 (8.00)18.2507
2000's7 (14.00)29.6817
2010's4 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kauffmann, HM; Schrenk, D1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Paumgartner, G; Reichen, J1
Mackinnon, M; Simon, F1
Gaito, JM; Miner, PB1
Coussediere, D; Cousty, C; Delaroff, V; Raynaud, JP; Salmon, J1
Mackinnon, AM; Simon, FR; Sutherland, E1
Challiner, MR; Park, BK; Whittaker, AD1
Fujimoto, JM; Peterson, RE1
Dybing, E; Mitchell, JR; Nelson, SD; Sasame, HA1
Davis, RA; Kern, F1
Shi, YE; Yager, JD1
Paumgartner, G1
Kitagawa, T; Lee, GH; Nomura, K1
Nakano, T; Sakamoto, M; Yanagi, S1
Connors, S; Vore, M1
Matangkasombut, OP; Sookvanichsilp, N1
Fischer, E; Pfeifenróth, A; Varga, F1
Bolt, HM; Kappus, H; Remmer, H3
Hom, FS; Miskel, JJ1
Accatino, L; Contreras, A; Gumucio, JJ; Macho, AM1
Götz, HG1
Arias, IM; Gatmaitan, Z; Levi, AJ; Reyes, H1
Hönicke, J; Köster, G; Wenzel, M1
Conney, AH; Levin, W; Welch, RM1
Patil, BJ; Souza, JM1
Accatino, L; Davis, RA; Gonzalez, M; Simon, FR; Sutherland, E1
Benrekassa, J; Decloitre, F1
Ito, N; Kurata, Y; Sakata, T; Shirai, T; Tamano, S; Tsuda, H1
Grabowski, PS; Maggs, JL; Park, BK1
Back, DJ; Breckenridge, AM; Crawford, F; Cross, K; MacIver, M; Orme, ML; Rowe, PH; Smith, E1
Cameron, RG; Imaida, K; Ito, N; Tsuda, H1
Cameron, R; Imaida, K; Ito, N1
Cole, FM; Sweeney, GD1
Back, DJ; Breckenridge, AM; Crawford, FE; Orme, ML; Rowe, PH1
Back, DJ; Bates, M; Bowden, A; Breckenridge, AM; Hall, MJ; Jones, H; MacIver, M; Orme, M; Perucca, E; Richens, A; Rowe, PH; Smith, E1
Guzelian, PS; Kocarek, TA; Schuetz, EG1
Asamoto, M; Baba-Toriyama, H; Ito, N; Kato, T; Kim, DJ; Mutai, M; Ozaki, K; Tsuda, H; Wada, S; Yamaguchi, S1
Alworth, WL; Hollenberg, PF; Kent, UM; Mills, DE; Rajnarayanan, RV1
Min, G1

Reviews

2 review(s) available for ethinyl estradiol and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
[Anti-dysmenorrhea drugs. 17].
    Pharmazeutische Praxis, 1967, Volume: 9

    Topics: Aminopyrine; Amphetamine; Analgesics; Aspirin; Atropa belladonna; Codeine; Dysmenorrhea; Ergot Alkaloids; Ergotamine; Esters; Ethinyl Estradiol; Female; Glycine; Hormones; Humans; Hypnotics and Sedatives; Methyltestosterone; Muscles; Papaverine; Phenacetin; Phenobarbital; Phytotherapy; Plants, Medicinal; Plants, Toxic; Quinine; Salicylamides

1967

Other Studies

48 other study(ies) available for ethinyl estradiol and phenobarbital

ArticleYear
Sequence analysis and functional characterization of the 5'-flanking region of the rat multidrug resistance protein 2 (mrp2) gene.
    Biochemical and biophysical research communications, 1998, Apr-17, Volume: 245, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Binding Sites; Carcinoma, Hepatocellular; Cisplatin; Clofibrate; Cloning, Molecular; Ethinyl Estradiol; Gene Expression Regulation, Neoplastic; Genes, MDR; Genes, Reporter; Phenobarbital; Rats; RNA, Messenger; Sequence Analysis, DNA; Transfection; Tumor Cells, Cultured

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Relationship between bile flow and Na+, K+-adenosinetriphosphatase in liver plasma membranes enriched in bile canaliculi.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Bile; Body Weight; Cell Membrane; Enzyme Activation; Ethinyl Estradiol; Gallbladder; Liver; Male; Methylcholanthrene; Microscopy, Electron; Organ Size; Phenobarbital; Potassium; Propylene Glycols; Rats; Sodium

1977
Pharmacological reversal of cholestasis-associated decrease in hepatic cytochrome P-450.
    Biochemical pharmacology, 1975, Mar-15, Volume: 24, Issue:6

    Topics: Animals; Bile Ducts; Cholestasis; Cytochrome P-450 Enzyme System; Depression, Chemical; Ethinyl Estradiol; Glucose-6-Phosphatase; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Rats

1975
Bile flow in response to pharmacologic agents. Hepatic DNA as a reference standard.
    Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7

    Topics: Animals; Bile; Body Weight; DNA; Ethinyl Estradiol; Liver; Male; Methylcholanthrene; Methylprednisolone; Organ Size; Phenobarbital; Rats

1979
Reference compounds for the study of moxestrol metabolism.
    Steroids, 1979, Volume: 34, Issue:4

    Topics: Animals; Bile; Chemical Phenomena; Chemistry; Estradiol Congeners; Ethinyl Estradiol; Gibberella; Hydroxylation; Phenobarbital; Rats

1979
Qualitative alteration in hepatic microsomal cytochrome P-450 apoproteins associated with bile duct ligation, and the administration of ethinyl estradiol, phenobarbital and 3-methylcholanthrene.
    Biochemical pharmacology, 1978, Jan-01, Volume: 27, Issue:1

    Topics: Animals; Apoproteins; Common Bile Duct; Cytochrome P-450 Enzyme System; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Ethinyl Estradiol; Ligation; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats

1978
The effect of enzyme induction on the irreversible binding of ethynyloestradiol to guinea pig liver microsomes.
    Life sciences, 1978, Dec-18, Volume: 23, Issue:25

    Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Ethinyl Estradiol; Flavonoids; Guinea Pigs; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rifampin; Spironolactone

1978
Increased biliary tree permeability produced in rats by hepatoactive agents.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:3

    Topics: Animals; Bile; Biliary Tract; Body Temperature; Cholic Acids; Dehydrocholic Acid; Drug Interactions; Ethinyl Estradiol; Female; Glycocholic Acid; Indocyanine Green; Injections; Liver; Mannitol; Permeability; Phenobarbital; Rats; Sucrose; Taurocholic Acid

1977
Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates.
    Biochemical and biophysical research communications, 1976, Jun-21, Volume: 70, Issue:4

    Topics: Aerobiosis; Anaerobiosis; Animals; Cytochrome P-450 Enzyme System; Estradiol; Estrogens; Estrone; Ethinyl Estradiol; Hydroxysteroids; Male; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Rats; Superoxide Dismutase

1976
Effects of ethinyl estradiol and phenobarbital on bile acid synthesis and biliary bile acid and cholesterol excretion.
    Gastroenterology, 1976, Volume: 70, Issue:6

    Topics: Animals; Bile Acids and Salts; Cholesterol; Ethinyl Estradiol; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats

1976
Stimulation of hepatocyte DNA synthesis by ethinyl estradiol.
    Progress in clinical and biological research, 1991, Volume: 369

    Topics: Animals; Cells, Cultured; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Ethinyl Estradiol; Female; Growth Substances; Hepatocyte Growth Factor; Kinetics; Liver; Liver Regeneration; Phenobarbital; Rats; Rats, Inbred Strains; Thymidine

1991
[Transport processes of bile secretion and its pharmacologic modification].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1986, Volume: 21

    Topics: Acid-Base Equilibrium; Bile; Bile Acids and Salts; Bile Canaliculi; Bile Ducts, Intrahepatic; Ethinyl Estradiol; Humans; Membrane Potentials; Phenobarbital; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Water-Electrolyte Balance

1986
Comparative study of diethylnitrosamine-initiated two-stage hepatocarcinogenesis in C3H, C57BL and BALB mice promoted by various hepatopromoters.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Animals; Clofibrate; Diethylnitrosamine; Ethinyl Estradiol; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Phenobarbital; Species Specificity

1989
Comparative study on pyruvate kinase activity-reducing action of various promoters of hepatocarcinogenesis.
    International journal of cancer, 1986, Mar-15, Volume: 37, Issue:3

    Topics: Animals; Body Weight; Carcinogens; Dexamethasone; Diet; Ethinyl Estradiol; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Niacin; Organ Size; Phenobarbital; Pyruvate Kinase; Rats; Rats, Inbred Strains

1986
Coregulation of C3-hydroxyl versus C17-hydroxyl glucuronidation of beta-estradiol in pregnancy and after treatment with phenobarbital or ethinyl-estradiol.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: Algorithms; Animals; Estradiol; Ethinyl Estradiol; Female; Kinetics; Ovary; Phenobarbital; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains

1988
Effect of diazepam and phenobarbital sodium on postcoital contraceptive efficacy of ethinyl estradiol in rats.
    Contraception, 1986, Volume: 34, Issue:2

    Topics: Animals; Contraceptives, Postcoital; Diazepam; Drug Interactions; Embryo Implantation; Ethinyl Estradiol; Female; Phenobarbital; Pregnancy; Rats; Uterine Contraction

1986
The role of bile acids in the effect of ethinylestradiol on the biliary excretion of exogenous organic anions.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1985, Volume: 8

    Topics: Animals; Anions; Bile; Bile Acids and Salts; Cholestyramine Resin; Drug Interactions; Ethinyl Estradiol; Liver; Phenobarbital; Rats; Rose Bengal; Taurocholic Acid

1985
Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro.
    Steroids, 1973, Volume: 22, Issue:2

    Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Charcoal; Chromatography, Gel; Chromatography, Ion Exchange; Endoplasmic Reticulum; Estradiol; Ethinyl Estradiol; Female; Hydroxylation; Male; Microsomes, Liver; NADP; Peptide Fragments; Phenobarbital; Proadifen; Protein Binding; Proteins; Rats; Serum Albumin, Bovine; Time Factors; Tritium; Trypsin

1973
Studies on the metabolism of ethynylestradiol in vitro and in vivo: the significance of 2-hydroxylation and the formation of polar products.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:12

    Topics: Animals; Carbon Monoxide; Chromatography; Chromatography, Thin Layer; Estradiol; Estrone; Ethinyl Estradiol; Glutathione; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Silicon Dioxide; Spectrophotometry, Ultraviolet; Tritium

1973
Oral dosage form design and its influence on dissolution rates for a series of drugs.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:6

    Topics: Administration, Oral; Capsules; Dicumarol; Diethylstilbestrol; Digitoxin; Dosage Forms; Drug Compounding; Ethinyl Estradiol; Gastric Juice; Hydrocortisone; Phenobarbital; Phenylbutazone; Propylthiouracil; Reserpine; Solubility; Spectrophotometry; Sulfadiazine; Surface-Active Agents; Tablets; Time Factors; Ultraviolet Rays

1970
Demethylation of mestranol to ethinyloestradiol in vitro and in vivo.
    Acta endocrinologica, 1972, Volume: 71, Issue:2

    Topics: Animals; Body Water; Carbon Isotopes; Chromatography; DDT; Ethinyl Estradiol; Female; Hydrogenation; In Vitro Techniques; Male; Mestranol; Methods; Methylation; Microsomes, Liver; Phenobarbital; Rats; Spirometry; Time Factors; Tritium

1972
Effect of phenobarbital on the ethynyl estradiol-induced cholestasis in the rat.
    Gastroenterology, 1973, Volume: 65, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Cycloheximide; Dactinomycin; Ethinyl Estradiol; Female; Injections, Intraperitoneal; Injections, Intravenous; Liver; Phenobarbital; Rats; Stimulation, Chemical; Time Factors

1973
Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:11

    Topics: Allyl Compounds; Animals; Benzopyrenes; Cholestasis; DDT; Densitometry; Dieldrin; Dwarfism, Pituitary; Electrophoresis, Disc; Ethinyl Estradiol; Hypophysectomy; Indocyanine Green; Liver; Male; Methylcholanthrene; Phenobarbital; Protein Binding; Proteins; Rats; Sulfobromophthalein; Thyroid Hormones; Thyroidectomy

1971
[A simple in vivo test for barbiturate induced hydroxylases using tritium labelled steroids as indicators].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1970, Volume: 8, Issue:3

    Topics: Animals; Body Fluids; Enzyme Induction; Estradiol; Ethinyl Estradiol; Female; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Testosterone; Tritium

1970
Decreased uterotropic potency of oral contraceptives in rats pretreated with phenobarbital.
    Endocrinology, 1968, Volume: 83, Issue:1

    Topics: Animals; Carbon Isotopes; Contraceptives, Oral; Diethylstilbestrol; Ethinyl Estradiol; Female; Liver; Mestranol; Microsomes; Norethindrone; Norethynodrel; Organ Size; Phenobarbital; Rats; Tritium; Uterus

1968
A study of 'Menopax Forte' in menopausal and postmenopausal disorders.
    The Indian practitioner, 1966, Volume: 19, Issue:12

    Topics: Adult; Ethinyl Estradiol; Female; Humans; Menopause; Methyltestosterone; Middle Aged; Phenobarbital; Tablets

1966
Reversal of ethinyl estradiol-induced bile secretory failure with Triton WR-1339.
    The Journal of clinical investigation, 1980, Volume: 65, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Cycloheximide; Ethinyl Estradiol; Liver; Male; Membrane Lipids; Membranes; Organ Size; Phenobarbital; Polyethylene Glycols; Rats; Sodium-Potassium-Exchanging ATPase

1980
Inhibition by 17-alpha-ethinyl estradiol of benzo[a]-pyrene metabolism in isolated adult rat hepatocytes.
    Biochemical pharmacology, 1983, Jan-15, Volume: 32, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; DNA; Ethinyl Estradiol; In Vitro Techniques; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains

1983
Modification of N-methyl-N-nitrosourea initiated carcinogenesis in the rat by subsequent treatment with antioxidants, phenobarbital and ethinyl estradiol.
    Cancer letters, 1984, Volume: 24, Issue:1

    Topics: Animals; Antioxidants; Cocarcinogenesis; Ethinyl Estradiol; Male; Methylnitrosourea; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344

1984
Drug-protein conjugates--II. An investigation of the irreversible binding and metabolism of 17 alpha-ethinyl estradiol in vivo.
    Biochemical pharmacology, 1983, Jan-15, Volume: 32, Issue:2

    Topics: Animals; Bile; Cysteine; Enzyme Induction; Ethinyl Estradiol; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains

1983
Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.
    Ciba Foundation symposium, 1980, Volume: 76

    Topics: Animals; Antipyrine; Contraceptives, Oral; Environment; Ethinyl Estradiol; Female; Half-Life; Humans; Intestinal Mucosa; Jejunum; Kinetics; Norethindrone; Norgestrel; Phenobarbital; Rats; Rifampin

1980
Promotive effects of steroids and bile acids on hepatocarcinogenesis initiated by diethylnitrosamine.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Animals; Bile Acids and Salts; Carcinogens; Cortisone; Dexamethasone; Diethylnitrosamine; Ethinyl Estradiol; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred F344; Testosterone

1982
Promotive effects of ethinyl estradiol in hepatocarcinogenesis initiated by diethylnitrosamine in male rats.
    Gan, 1981, Volume: 72, Issue:2

    Topics: Animals; Diethylnitrosamine; Drug Synergism; Ethinyl Estradiol; Hyperplasia; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats

1981
Effects of ethynyl estradiol on liver microsomal mixed function oxygenase activity in male rats.
    Laboratory investigation; a journal of technical methods and pathology, 1980, Volume: 42, Issue:2

    Topics: Animals; Ethinyl Estradiol; Female; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Phenobarbital; Rats

1980
Phenobarbitone interaction with oral contraceptive steroids in the rabbit and rat.
    British journal of pharmacology, 1980, Volume: 69, Issue:3

    Topics: Animals; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Digestive System; Drug Interactions; Enzyme Induction; Ethinyl Estradiol; Female; Kinetics; Norethindrone; Phenobarbital; Rabbits; Rats; Sleep; Time Factors

1980
The interaction of phenobarbital and other anticonvulsants with oral contraceptive steroid therapy.
    Contraception, 1980, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Contraceptives, Oral; Drug Interactions; Ethinyl Estradiol; Female; Gonadal Steroid Hormones; Humans; Norethindrone; Norgestrel; Phenobarbital; Prospective Studies; Retrospective Studies

1980
Regulation of cytochrome P450 2B1/2 mRNAs by Kepone (chlordecone) and potent estrogens in primary cultures of adult rat hepatocytes on Matrigel.
    Toxicology letters, 1994, Volume: 71, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Cells, Cultured; Chloral Hydrate; Chlordecone; Cytochrome P-450 Enzyme System; Diethylstilbestrol; Estradiol; Estrogens; Ethinyl Estradiol; Female; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid Hydroxylases

1994
Modifying influence of swine-serum-induced liver fibrosis on development of preneoplastic lesions in rat liver.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Blood; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Deoxycholic Acid; Ethinyl Estradiol; Glutathione Transferase; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Liver Diseases; Male; Organ Size; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Swine

1996
Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethinyl Estradiol; Humans; In Vitro Techniques; Isoenzymes; Liver; Male; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Long-Evans; Spectrophotometry, Ultraviolet; Steroid Hydroxylases; Substrate Specificity

2002
Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells.
    Experimental & molecular medicine, 2010, Nov-30, Volume: 42, Issue:11

    Topics: Constitutive Androstane Receptor; Corticosterone; Estrogens; Ethinyl Estradiol; Hep G2 Cells; Humans; Liver; Liver X Receptors; Orphan Nuclear Receptors; Phenobarbital; Pregnane X Receptor; Pyridines; Receptor Cross-Talk; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Response Elements; Rifampin; Transcriptional Activation

2010