ethinyl estradiol has been researched along with nadp in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldziecher, JW; Helton, ED; Williams, MC | 1 |
| Bolt, HM; Kappus, H; Remmer, H | 2 |
| Bolt, HM; Kappus, H | 1 |
| Halterman, DR; Kuo, MC; Lucas, FV; Martin, AP; Vorbeck, ML | 1 |
| Barbieri, RL; Canick, JA; Petro, Z; Ryan, KJ | 1 |
| Barth, A; Karge, E; Klinger, W; Landmann, G; Liepold, K; Müller, D; Zapf, H | 1 |
| Hollenberg, PF; Kent, UM; Lin, HL | 1 |
| Hollenberg, PF; Lin, HL | 1 |
9 other study(ies) available for ethinyl estradiol and nadp
| Article | Year |
|---|---|
Oxidative metabolism and de-ethynylation of 17alpha-ethynylestradiol by baboon liver microsomes.
Topics: Animals; Biotransformation; Estradiol; Estrone; Ethinyl Estradiol; Female; Haplorhini; Male; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Papio; Protein Binding; Sexual Maturation | 1977 |
Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Charcoal; Chromatography, Gel; Chromatography, Ion Exchange; Endoplasmic Reticulum; Estradiol; Ethinyl Estradiol; Female; Hydroxylation; Male; Microsomes, Liver; NADP; Peptide Fragments; Phenobarbital; Proadifen; Protein Binding; Proteins; Rats; Serum Albumin, Bovine; Time Factors; Tritium; Trypsin | 1973 |
Studies on the metabolism of ethynylestradiol in vitro and in vivo: the significance of 2-hydroxylation and the formation of polar products.
Topics: Animals; Carbon Monoxide; Chromatography; Chromatography, Thin Layer; Estradiol; Estrone; Ethinyl Estradiol; Glutathione; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Silicon Dioxide; Spectrophotometry, Ultraviolet; Tritium | 1973 |
Irreversible binding of ethynylestradiol metabolites to protein: lack of methylation by S-adenosyl-methionine.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Catechol O-Methyltransferase; Chromatography, Gel; Cytosol; Ethinyl Estradiol; Glutathione; Isotope Labeling; Liver; Methylation; Microsomes, Liver; NADP; Oxidation-Reduction; Protein Binding; Proteins; Rats; Receptors, Drug; S-Adenosylmethionine; Tritium | 1974 |
Metabolism of norethynodre, a 19-nor progestin: subcellular localization of enzyme activity.
Topics: Animals; Chromatography; Ethinyl Estradiol; Humans; In Vitro Techniques; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; NADP; Norethynodrel; Rats; Spectrophotometry; Tritium | 1970 |
Aromatization of norethindrone to ethinyl estradiol by human placental microsomes.
Topics: Borohydrides; Cytochrome P-450 Enzyme System; Ethinyl Estradiol; Female; Humans; Kinetics; Microsomes; NADP; Norethindrone; Oxygen; Placenta; Pregnancy | 1983 |
Influence of oestrogens on formation of reactive oxygen species in liver microsomes of differently aged male Wistar rats.
Topics: Aging; Animals; Estradiol; Estrogens; Ethinyl Estradiol; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Luminescent Measurements; Male; Microsomes, Liver; NADP; Rats; Rats, Wistar; Reactive Oxygen Species | 1999 |
Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein.
Topics: Apoproteins; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Ethinyl Estradiol; Gas Chromatography-Mass Spectrometry; Heme; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Protein Binding; Solubility; Spectrometry, Mass, Electrospray Ionization | 2002 |
The inactivation of cytochrome P450 3A5 by 17alpha-ethynylestradiol is cytochrome b5-dependent: metabolic activation of the ethynyl moiety leads to the formation of glutathione conjugates, a heme adduct, and covalent binding to the apoprotein.
Topics: Apoproteins; Biotransformation; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochromes b5; Endopeptidases; Enzyme Inhibitors; Ethinyl Estradiol; Glutathione; Heme; Humans; Mass Spectrometry; NADP; Spectrometry, Mass, Electrospray Ionization | 2007 |