Page last updated: 2024-08-17

ethinyl estradiol and methotrexate

ethinyl estradiol has been researched along with methotrexate in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's0 (0.00)18.2507
2000's6 (28.57)29.6817
2010's9 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I1
Jolivette, LJ; Ward, KW1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Flubacher, P; Hartmann, D; Meier, V; Obrecht, JP1
Dalcq, JM; Derriks, R; Laurent, C; Mannes, P; Moens, R1
Aherne, GW; English, J; Marks, V1
Byland, W; Nagel, G; Senn, HJ1
Derriks, R; Heynen, E; Mannes, P; Moens, R1
DEDERICK, MM; HALL, TC; LOJANANOND, P; TAFT, PD1
Chi, HY; Choi, MK; Choi, YA; Kang, YJ; Kim, MJ; Kwon, M; Shim, CK; Song, IS; Yoo, HH1

Other Studies

21 other study(ies) available for ethinyl estradiol and methotrexate

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
    Molecular pharmacology, 2003, Volume: 63, Issue:2

    Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection

2003
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Cytostatic pneumopathy following chemotherapy for metastasizing breast neoplasm].
    Schweizerische medizinische Wochenschrift, 1977, Oct-08, Volume: 107, Issue:40

    Topics: Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Ethinyl Estradiol; Female; Femoral Vein; Fluorouracil; Humans; Lung Diseases; Methotrexate; Prednisone; Pulmonary Alveoli; Pulmonary Fibrosis; Thrombophlebitis; Vincristine

1977
Multidisciplinary curative treatment for disseminated carcinoma of the breast.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Androgens; Antineoplastic Agents; Breast Neoplasms; Castration; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Ethinyl Estradiol; Female; Fluorouracil; Humans; Medroxyprogesterone; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous; Thoracic Neoplasms; Vincristine

1976
The role of immunoassay in the analysis of microcontaminants in water samples.
    Ecotoxicology and environmental safety, 1985, Volume: 9, Issue:1

    Topics: Ethinyl Estradiol; Hospitals; Immunoassay; Methotrexate; Norethindrone; Progesterone; Sewage; Steroids; Water Pollutants; Water Pollutants, Chemical; Water Supply

1985
[Hormone therapy and chemotherapy of metastasizing breast cancer. Experiences of the Basle Oncology Center, 1969-72].
    Schweizerische medizinische Wochenschrift, 1974, Aug-03, Volume: 104, Issue:31

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Castration; Cyclophosphamide; Drug Therapy, Combination; Estradiol; Estrogens; Ethinyl Estradiol; Female; Fluorouracil; Hormones; Humans; Hypophysectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Ovary; Prednisone; Recurrence; Remission, Spontaneous; Vincristine

1974
[Antineoplastic polychemotherapy in thoracic pathology].
    Le Poumon et le coeur, 1968, Volume: 24, Issue:1

    Topics: Adrenalectomy; Aged; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cortisone; Cyclophosphamide; Drug Synergism; Ethinyl Estradiol; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrazines; Hypophysectomy; Kidney Neoplasms; Lung Neoplasms; Male; Melanoma; Melphalan; Mesothelioma; Methotrexate; Middle Aged; Nandrolone; Neoplasm Metastasis; Ovarian Neoplasms; Podophyllin; Sarcoma; Thiotepa; Vinblastine

1968
EFFECT OF THERAPY UPON VAGINAL SMEARS IN BREAST CANCER PATIENTS.
    Surgery, gynecology & obstetrics, 1964, Volume: 118

    Topics: Animals; Biomedical Research; Breast Neoplasms; Diethylstilbestrol; Ethinyl Estradiol; Female; Fluorometholone; Gonadotropins; Gonadotropins, Equine; Horses; Humans; Methotrexate; Methyltestosterone; Pharmacology; Prednisone; Testosterone; Vaginal Smears

1964
Ursodeoxycholate Restores Biliary Excretion of Methotrexate in Rats with Ethinyl Estradiol Induced-Cholestasis by Restoring Canalicular Mrp2 Expression.
    International journal of molecular sciences, 2018, Apr-09, Volume: 19, Issue:4

    Topics: Administration, Oral; Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis; Down-Regulation; Drug Administration Schedule; Ethinyl Estradiol; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Rats; Treatment Outcome; Ursodeoxycholic Acid

2018