ethinyl estradiol has been researched along with ketoconazole in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Remmel, RP; Tracy, TS; Zhou, J | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Back, DJ; Stevenson, P; Tjia, JF | 1 |
| Hámori, M; Kovács, I; Somos, P | 1 |
| Friedman, HL; Greenblatt, DJ; Karsov, D; Schmider, J; Shader, RI; Vena, R; von Moltke, LL | 1 |
| Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S | 1 |
| Haehner, T; Müller-Enoch, D; Refaie, MO | 1 |
| Celander, MC; Hasselberg, L; Wassmur, B; Westerberg, S | 1 |
| Fortuny, A; Mañanós, E; Solé, M | 1 |
| Berse, M; Gschwend, S; Höchel, J; Klein, S; Schütt, B; Wiesinger, H; Zollmann, FS | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
2 trial(s) available for ethinyl estradiol and ketoconazole
| Article | Year |
|---|---|
A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism.
Topics: Adult; Cyproterone Acetate; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Hormones; Humans; Ketoconazole; Prospective Studies | 1999 |
Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol.
Topics: Adult; Androstenes; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Estradiol; Ethinyl Estradiol; Female; Humans; Ketoconazole; Middle Aged | 2015 |
17 other study(ies) available for ethinyl estradiol and ketoconazole
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors.
Topics: Bilirubin; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Humans; Pharmaceutical Preparations; Recombinant Proteins; Substrate Specificity | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparative effects of two antimycotic agents, ketoconazole and terbinafine on the metabolism of tolbutamide, ethinyloestradiol, cyclosporin and ethoxycoumarin by human liver microsomes in vitro.
Topics: Antifungal Agents; Coumarins; Cyclosporins; Cytochrome P-450 Enzyme System; Ethinyl Estradiol; Female; Humans; In Vitro Techniques; Ketoconazole; Male; Microsomes, Liver; Naphthalenes; Terbinafine; Tolbutamide | 1989 |
Examination of the potential interaction between ketoconazole (Nizoral) and oral contraceptives with special regard to products of low hormone content (Rigevidon, anteovin).
Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Contraceptives, Oral, Hormonal; Contraceptives, Postcoital; Contraceptives, Postcoital, Hormonal; Drug Interactions; Ethinyl Estradiol; Ethinyl Estradiol-Norgestrel Combination; Female; Humans; Ketoconazole; Menstruation Disturbances; Norgestrel | 1986 |
Biotransformation of mestranol to ethinyl estradiol in vitro: the role of cytochrome P-450 2C9 and metabolic inhibitors.
Topics: Adult; Antifungal Agents; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol Congeners; Ethinyl Estradiol; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Mestranol; Microsomes, Liver | 1997 |
Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.
Topics: Antifungal Agents; Antimalarials; Catalysis; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Estrogen Antagonists; Ethinyl Estradiol; Flavanones; Hormone Antagonists; Humans; Immunosuppressive Agents; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Mifepristone; NADPH-Ferrihemoprotein Reductase; Phospholipids; Quinidine; Quinine; Tacrolimus | 2004 |
Ketoconazole, an antifungal imidazole, increases the sensitivity of rainbow trout to 17alpha-ethynylestradiol exposure.
Topics: Animals; Antibodies; Antifungal Agents; Blotting, Western; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Estrogens; Ethinyl Estradiol; Female; Gene Expression Regulation; Gonadal Hormones; Ketoconazole; Male; Microsomes, Liver; Oncorhynchus mykiss; RNA, Messenger; Time Factors; Vitellogenins | 2008 |
Effects of selected xenobiotics on hepatic and plasmatic biomarkers in juveniles of Solea senegalensis.
Topics: Animals; Biomarkers; Ethinyl Estradiol; Flatfishes; Flavones; Gemfibrozil; Gonadal Steroid Hormones; Hydrolysis; Ketoconazole; Microsomes, Liver; Phenols; Receptors, Aryl Hydrocarbon; Statistics, Nonparametric; Vitellogenins; Xenobiotics | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |