ethinyl estradiol has been researched along with heme in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hollenberg, PF; Kent, UM; Lin, HL | 1 |
| Hollenberg, PF; Sridar, C; Von Weymarn, LB | 1 |
| Hollenberg, PF; Lin, HL | 1 |
| Atkins, WM; Bowman, MK; Conner, KP; Krzyaniak, MD; Vennam, P; Woods, CM | 1 |
| Cerny, D; Dolezelova, E; Farghali, H; Fuksa, L; Lenicek, M; Micuda, S; Muchova, L; Suk, J; Vanova, K; Vitek, L; Vreman, HJ; Wong, RJ; Zelenkova, M | 1 |
5 other study(ies) available for ethinyl estradiol and heme
| Article | Year |
|---|---|
Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein.
Topics: Apoproteins; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Ethinyl Estradiol; Gas Chromatography-Mass Spectrometry; Heme; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Protein Binding; Solubility; Spectrometry, Mass, Electrospray Ionization | 2002 |
Identification of amino acid residues involved in the inactivation of cytochrome P450 2B1 by two acetylenic compounds: the role of three residues in nonsubstrate recognition Sites.
Topics: Alkynes; Amino Acids; Animals; Cytochrome P-450 CYP2B1; Enzyme Inhibitors; Ethers; Ethinyl Estradiol; Heme; Mutation; Rats; Recombinant Fusion Proteins | 2004 |
The inactivation of cytochrome P450 3A5 by 17alpha-ethynylestradiol is cytochrome b5-dependent: metabolic activation of the ethynyl moiety leads to the formation of glutathione conjugates, a heme adduct, and covalent binding to the apoprotein.
Topics: Apoproteins; Biotransformation; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochromes b5; Endopeptidases; Enzyme Inhibitors; Ethinyl Estradiol; Glutathione; Heme; Humans; Mass Spectrometry; NADP; Spectrometry, Mass, Electrospray Ionization | 2007 |
1,2,3-Triazole-heme interactions in cytochrome P450: functionally competent triazole-water-heme complexes.
Topics: Click Chemistry; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ethinyl Estradiol; Heme; Imidazoles; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Protein Binding; Quantum Theory; Thermodynamics; Triazoles; Water | 2012 |
Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis.
Topics: Alkaline Phosphatase; Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Bilirubin; Cells, Cultured; Cholestasis; Enzyme Induction; Ethinyl Estradiol; Female; Gene Expression; Heme; Heme Oxygenase (Decyclizing); Hepatocytes; Multidrug Resistance-Associated Proteins; Primary Cell Culture; Protective Agents; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Taurocholic Acid | 2015 |