Page last updated: 2024-08-17

ethinyl estradiol and ethinylestradiol-3-sulfate

ethinyl estradiol has been researched along with ethinylestradiol-3-sulfate in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199029 (63.04)18.7374
1990's2 (4.35)18.2507
2000's5 (10.87)29.6817
2010's7 (15.22)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Böhm, WD; Geissler, W; Gorski, J; Illig, HD; Koch, R1
Göretzlehner, G; Leminski, A; Ulrich, U; Weber, A; Wodrig, W1
Göretzlehner, G; Lembke, J; Leminski, A; Weber, A; Wodrig, W1
Bär, CM; Dörner, G; Fröhlich, G; Schnorr, D; Stahl, F1
Dörner, G; Guddat, HM; Rohde, W; Schnorr, D; Stahl, F2
Fiedler, R; Klebingat, KJ; Lorenz, G; Panzig, E; Steinhauser, I1
Guddat, HM; Schnorr, D; Zemke, F1
Dörner, G; Guddat, HM; Rhode, W; Schnorr, D; Stahl, F1
Dörner, G; Rohde, W; Schnorr, D; Stahl, F2
Drawz, B; Drawz, G; Hoffmann, L; Russbüldt, R1
Schott, H; Zade, W1
Sladczyk, E1
Brachmann, K; Göretzlehner, G; Männchen, E; Nikschick, S2
Kunkel, S; Meissner, J; Rudolf, K; Rüting, M1
Blödow, K; Kunkel, S; Rudolf, K1
Kunkel, S; Rudolf, K; Woltanski, KP1
Kunkel, S; Rudolf, H; Rudolf, K1
Görlich, M; Gürtler, R1
Carol, W; Klinger, G; Lauterbach, H1
Kindt, J; Retzke, U; Scheunert, EU1
Chemnitius, KH; Machnik, G; Niekrenz, H1
Chemnitius, KH; Claussen, C; Huebler, D; Naumann, A1
Castracane, VD; Goldzieher, JW; Moore, PH; Newburger, J; Williams, MC1
Bodek, B; Gürtler, R; Morack, G; Tanneberger, S1
Claussen, C; Klinger, G; Schröder, S1
Fotherby, K; Reed, MJ1
Carver, JM; Lundeen, SG; McKean, ML; Winneker, RC1
Benet, LZ; Bornheim, LM; Correia, MA; Hanstein, WG; Jäger, W; Mahnke, A; Xue, L1
Braun, MP; Chu, XY; Evans, DC; Evers, R; Huskey, SE; Sarkadi, B1
Kagayama, A; Niwa, T; Ohno, Y; Shiraga, T1
Bosveld, AT; Rouhani Rankouhi, T; Sanderson, JT; van den Berg, M; van Holsteijn, I; van Kooten, P1
Hayashi, M; Kawashima, K; Mizuma, T; Sakaguchi, S; Sakai, S1
Busler, D; Chen, C; Han, YH; Hong, Y; Rodrigues, AD; Tian, Y2
Miyazawa, Y; Nakano, K; Nakata, S; Sasaki, Y; Takahashi, H1
Day, JS; Hillgren, KM; Phillips, DL; Zamek-Gliszczynski, MJ1
Chen, S; Fu, Z; Jin, Y; Li, Y; Lin, X; Miao, W; Pan, Q; Shen, H; Wu, T1
Berman, J; Burlington, DB; Chaudry, IH; Grudzinskas, C; Hubbard, W; Keith, J; Miller, M; Peck, C; Scott, C1
Berman, J; Chaudry, IH; Hubbard, W; Keith, J; Miller, M; Peck, C; Scott, C1
Chaudry, IH; Hubbard, WJ; Yang, S1
Abdou, H; Berman, J; Chaudry, IH; Edwards, J; Elansary, N; Gopalakrishnan, M; Hubbard, WJ; Lang, E; Morrison, JJ; Patel, N; Richmond, MJ; Scalea, TM1
Cap, AP; Le, TD; Martini, WZ; Xia, H1

Trials

4 trial(s) available for ethinyl estradiol and ethinylestradiol-3-sulfate

ArticleYear
[Clinical value of ethinyl estradiol sulfonate (Turisteron)--long-term results of a randomized compound study].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Aged; Clinical Trials as Topic; Combined Modality Therapy; Ethinyl Estradiol; Follow-Up Studies; Humans; Male; Neoplasm Staging; Palliative Care; Prostatic Neoplasms; Random Allocation

1987
[Cellular immunity in prostatic cancer modified by Cytonal, Estrazyt and Turisteron].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Aged; Antineoplastic Agents; Clinical Trials as Topic; Combined Modality Therapy; Diethylstilbestrol; Estramustine; Ethinyl Estradiol; Humans; Immunity, Cellular; Macrophages; Male; Middle Aged; Nitrogen Mustard Compounds; Prostatic Neoplasms; Random Allocation

1987
[Initial results of a phase IV multicenter clinical trial of Turisteron in the treatment of prostate cancer].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Combined Modality Therapy; Ethinyl Estradiol; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Prostatic Neoplasms

1987
Assessment of ethynylestradiol-3-sulfate on coagulation, metabolism, and survival in pigs with traumatic hemorrhage.
    The journal of trauma and acute care surgery, 2023, 11-01, Volume: 95, Issue:5

    Topics: Animals; Blood Coagulation; Ethinyl Estradiol; Hemorrhage; Oxygen; Resuscitation; Shock, Hemorrhagic; Swine

2023

Other Studies

42 other study(ies) available for ethinyl estradiol and ethinylestradiol-3-sulfate

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Pituitary response in the doubled GnRH-TRH test on the 5th day post partum or post abortum after ablactation by oral means of ethinylestradiol sulfonate.
    Experimental and clinical endocrinology, 1989, Volume: 94, Issue:1-2

    Topics: Abortion, Spontaneous; Administration, Oral; Adolescent; Adult; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypophyseal System; Lactation; Luteinizing Hormone; Pituitary Hormone-Releasing Hormones; Postpartum Period; Pregnancy; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone

1989
[The double GnRH-TRH test following control of lactation with ethinyl estradiol sulfonate after abortion, early and term labor].
    Gynakologische Rundschau, 1989, Volume: 29 Suppl 2

    Topics: Abortion, Spontaneous; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Infant, Newborn; Lactation; Obstetric Labor, Premature; Pregnancy; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone

1989
Suppression of plasma androgen levels with a combination therapy of depot-estrogen (Turisteron) and Dexamethasone in patients with prostatic cancer.
    Experimental and clinical endocrinology, 1989, Volume: 94, Issue:3

    Topics: Aged; Aged, 80 and over; Androgens; Dexamethasone; Drug Therapy, Combination; Ethinyl Estradiol; Humans; Male; Middle Aged; Prostatic Neoplasms

1989
[Conservative therapy of prostate cancer using Turisteron].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Ethinyl Estradiol; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Prostatic Neoplasms; Testosterone

1987
[Behavior of LH, FSH, total testosterone, free testosterone and SHBG serum levels in the therapy of prostatic cancer with Turisteron (ethinyl estradiol sulfonate)].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:12

    Topics: Ethinyl Estradiol; Follicle Stimulating Hormone; Follow-Up Studies; Gonadal Steroid Hormones; Humans; Luteinizing Hormone; Male; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Testosterone

1987
[Clinical study of ethinyl estradiol sulfonate in conservative therapy of prostate cancer].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Combined Modality Therapy; Drug Implants; Ethinyl Estradiol; Humans; Luteinizing Hormone; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Testosterone

1987
[Inhibition of the free, biologically active testosterone level by Turisteron in patients with prostate cancer].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Delayed-Action Preparations; Diethylstilbestrol; Ethinyl Estradiol; Humans; Luteinizing Hormone; Male; Middle Aged; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Testosterone

1987
[Experiences in the treatment of advanced prostatic cancer using Turisteron with special reference to cardiovascular complications].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Carcinoma; Cardiovascular Diseases; Ethinyl Estradiol; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk

1987
[Liver damage in hormone therapy of prostate cancer].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Diethylstilbestrol; Ethinyl Estradiol; Humans; Liver Function Tests; Male; Middle Aged; Prostatic Neoplasms

1987
[Clinical experience using Turisteron in the treatment of prostatic cancer].
    Zeitschrift fur Urologie und Nephrologie, 1987, Volume: 80, Issue:3

    Topics: Aged; Drug Resistance; Ethinyl Estradiol; Humans; Male; Prognosis; Prostatic Neoplasms

1987
The influence of a sequential-type oral contraceptive with ethinylestradiol-sulfonate soft gelatin capsules and norethisterone acetate on carbohydrate metabolism during the first twelve months.
    Experimental and clinical endocrinology, 1985, Volume: 85, Issue:3

    Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Contraceptives, Oral; Contraceptives, Oral, Sequential; Delayed-Action Preparations; Ethinyl Estradiol; Female; Humans; Insulin; Norethindrone; Norethindrone Acetate; Time Factors

1985
Successful treatment of prostatic cancer with the orally active depot estrogen ethinylestradiol sulfonate (Turisteron).
    Experimental and clinical endocrinology, 1985, Volume: 86, Issue:2

    Topics: Aged; Delayed-Action Preparations; Ethinyl Estradiol; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testosterone

1985
[Effect of ethinyl estradiol sulfonate/norethisterone acetate on gonadotropin secretion in pubertal girls].
    Zentralblatt fur Gynakologie, 1985, Volume: 107, Issue:22

    Topics: Adolescent; Body Height; Child; Drug Therapy, Combination; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Norethindrone; Norethindrone Acetate; Pituitary Hormone-Releasing Hormones; Puberty; Radioimmunoassay

1985
[Effect of ethinyl estradiol sulfonate/norethisterone acetate on PRI secretion in pubertal girls].
    Zentralblatt fur Gynakologie, 1985, Volume: 107, Issue:22

    Topics: Adolescent; Body Height; Child; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Norethindrone; Norethindrone Acetate; Prolactin; Puberty; Radioimmunoassay; Thyrotropin-Releasing Hormone

1985
[Effect of ethinyl estradiol sulfonate/norethisterone acetate on HGH secretion in pubertal girls].
    Zentralblatt fur Gynakologie, 1985, Volume: 107, Issue:22

    Topics: Adolescent; Adult; Arginine; Body Height; Chorionic Gonadotropin; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Norethindrone; Norethindrone Acetate; Pituitary Hormone-Releasing Hormones; Puberty; Radioimmunoassay; Thyrotropin-Releasing Hormone

1985
[Effect of ethinyl estradiol sulfonate/norethisterone acetate on TSH, T4, TBC and the FT4 index in pubertal girls].
    Zentralblatt fur Gynakologie, 1985, Volume: 107, Issue:22

    Topics: Adolescent; Arginine; Body Height; Child; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Norethindrone; Norethindrone Acetate; Pituitary Hormone-Releasing Hormones; Puberty; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Thyroxine-Binding Proteins

1985
Clinical relevance of steroid hormone receptors.
    Archiv fur Geschwulstforschung, 1985, Volume: 55, Issue:5

    Topics: Adrenal Cortex Hormones; Breast Neoplasms; Ethinyl Estradiol; Female; Humans; Prognosis; Receptors, Estradiol; Receptors, Progesterone; Receptors, Steroid; Tamoxifen

1985
[Effect of sequential preparation with ethinyl estradiol sulfonate soft gelatin capsules and norethindrone acetate on carbohydrate metabolism].
    Zentralblatt fur Gynakologie, 1984, Volume: 106, Issue:6

    Topics: Adult; Blood Glucose; Capsules; Drug Administration Schedule; Ethinyl Estradiol; Female; Gelatin; Glucose Tolerance Test; Humans; Insulin; Norethindrone; Norethindrone Acetate; Pharmaceutical Vehicles

1984
[Testing of the steroid-related suppressive effect on the hypothalamo-hypophyseal system using twofold stimulation].
    Zentralblatt fur Gynakologie, 1984, Volume: 106, Issue:6

    Topics: Contraceptives, Oral, Combined; Drug Combinations; Ethinyl Estradiol; Ethinyl Estradiol-Norgestrel Combination; Female; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Menstruation; Norethindrone; Norgestrel; Pituitary Hormone-Releasing Hormones; Prolactin; Thyrotropin-Releasing Hormone

1984
[Effect of ethinyl estradiol sulfonate on the urethral epithelium after bilateral oophorectomy].
    Zentralblatt fur Gynakologie, 1984, Volume: 106, Issue:14

    Topics: Adult; Castration; Drug Evaluation; Epithelial Cells; Epithelium; Ethinyl Estradiol; Female; Humans; Male; Middle Aged; Postoperative Period; Time Factors; Urethra

1984
Liver neoplasms after long-term steroid application in rats.
    Experimental pathology, 1983, Volume: 24, Issue:2-3

    Topics: Adrenal Gland Neoplasms; Animals; Ethinyl Estradiol; Female; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Pituitary Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1983
Pharmacokinetics of ethynyl estradiolsulfonate in minipigs.
    Hormone research, 1984, Volume: 19, Issue:1

    Topics: Administration, Oral; Animals; Ethinyl Estradiol; Injections, Intravenous; Kinetics; Male; Swine; Swine, Miniature

1984
The pharmacokinetics and metabolism of ethinyl estradiol and its three sulfates in the baboon.
    American journal of obstetrics and gynecology, 1983, May-01, Volume: 146, Issue:1

    Topics: Administration, Oral; Animals; Castration; Ethinyl Estradiol; Female; Half-Life; Injections, Intravenous; Kinetics; Models, Biological; Papio; Radioimmunoassay

1983
[Clinical experience with the depot estrogen Turisteron in the treatment of metastatic breast cancer (author's transl)].
    Archiv fur Geschwulstforschung, 1982, Volume: 52, Issue:2

    Topics: Aged; Breast Neoplasms; Delayed-Action Preparations; Drug Evaluation; Ethinyl Estradiol; Female; Humans; Middle Aged; Prognosis

1982
[Excretion of ethinyloestradiol sulfonate in the human milk (author's transl)].
    Zentralblatt fur Gynakologie, 1981, Volume: 103, Issue:2

    Topics: Chromatography, Thin Layer; Ethinyl Estradiol; Female; Humans; Lactation; Milk, Human; Pregnancy

1981
Interaction of ethynyloestradiol sulphate with plasma proteins.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:5

    Topics: Binding Sites; Binding, Competitive; Blood Proteins; Chemical Phenomena; Chemistry; Estrone; Ethinyl Estradiol; Female; Humans; Male; Protein Binding; Serum Albumin

1980
Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels.
    Endocrinology, 1997, Volume: 138, Issue:4

    Topics: Animals; Cholesterol; Dexamethasone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Lipids; Ovariectomy; Piperidines; Progesterone; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1997
Ethynylestradiol-mediated induction of hepatic CYP3A9 in female rats: implication for cyclosporine metabolism.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:12

    Topics: Actins; Animals; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethinyl Estradiol; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunosuppressive Agents; Liver; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats

1999
Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1

    Topics: Animals; Biological Transport; Cell Line; Cell Membrane; Drug Interactions; Estradiol; Ethinyl Estradiol; Insecta; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Tritium

2004
Interindividual variability in 2-hydroxylation, 3-sulfation, and 3-glucuronidation of ethynylestradiol in human liver.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:12

    Topics: Adolescent; Adult; Aged; Ethinyl Estradiol; Female; Glucuronides; Humans; Hydroxylation; Liver; Male; Middle Aged; Sulfates

2004
Effects of environmental and natural estrogens on vitellogenin production in hepatocytes of the brown frog (Rana temporaria).
    Aquatic toxicology (Amsterdam, Netherlands), 2005, Jan-18, Volume: 71, Issue:1

    Topics: Animals; Benzhydryl Compounds; Diethylstilbestrol; Estradiol; Estrogens; Estrone; Ethinyl Estradiol; Female; Hepatocytes; Male; Methoxychlor; Phenols; Rana temporaria; Vitellogenesis; Vitellogenins

2005
Differentiation of organ availability by sequential and simultaneous analyses: intestinal conjugative metabolism impacts on intestinal availability in humans.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:3

    Topics: Albuterol; Biological Availability; Ethinyl Estradiol; Models, Biological; Organ Specificity; Pharmaceutical Preparations; Terbutaline; Tissue Distribution

2005
Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human liver drug transporters.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:7

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Carrier Proteins; Cell Line, Transformed; Ethinyl Estradiol; Hepatocytes; Humans; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Symporters; Transfection

2010
Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:7

    Topics: Animals; Biological Transport; Carrier Proteins; Cell Line, Transformed; Dogs; Ethinyl Estradiol; Humans; Insecta; Kidney; Kinetics; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Substrate Specificity; Transfection

2010
[Prognostic factors for estrogen therapy of relapsed prostate cancer after maximal androgen blockade (MAB)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2010, Volume: 101, Issue:4

    Topics: Aged; Androgen Antagonists; Combined Modality Therapy; Diethylstilbestrol; Drug Therapy, Combination; Estramustine; Estrogens; Ethinyl Estradiol; Humans; Kaplan-Meier Estimate; Male; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Prostatic Neoplasms; Survival Rate; Time Factors

2010
Efflux transport is an important determinant of ethinylestradiol glucuronide and ethinylestradiol sulfate pharmacokinetics.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:10

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biliary Tract; Biological Transport; Cell Membrane; Estradiol; Ethinyl Estradiol; Half-Life; Intestinal Mucosa; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats; Rats, Wistar

2011
Chronic exposure of mice to environmental endocrine-disrupting chemicals disturbs their energy metabolism.
    Toxicology letters, 2014, Mar-21, Volume: 225, Issue:3

    Topics: Adipose Tissue; Animals; Atrazine; Body Weight; Cholesterol; Endocrine Disruptors; Energy Metabolism; Ethinyl Estradiol; Fatty Acids, Nonesterified; Liver; Male; Mice; Mice, Inbred C57BL; Pyrethrins; Random Allocation; Real-Time Polymerase Chain Reaction; RNA, Messenger; Triglycerides

2014
Efficacy of 17α-ethynylestradiol-3-sulfate for severe hemorrhage in minipigs in the absence of fluid resuscitation.
    The journal of trauma and acute care surgery, 2014, Volume: 76, Issue:6

    Topics: Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Ethinyl Estradiol; Fluid Therapy; Hemorrhage; Injections, Intravenous; Male; Resuscitation; Severity of Illness Index; Survival Rate; Swine; Swine, Miniature; Treatment Outcome

2014
17α-Ethynylestradiol-3-sulfate treatment of severe blood loss in rats.
    The Journal of surgical research, 2015, Volume: 193, Issue:1

    Topics: Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Ethinyl Estradiol; Hemorrhage; Hydrogen-Ion Concentration; Kaplan-Meier Estimate; Lactic Acid; Male; Rats, Sprague-Dawley; Sodium Chloride; Survival Rate; Trauma Severity Indices

2015
Ethinyl estradiol sulfate acts without fluid resuscitation through estrogen receptors to rapidly protect the cardiovascular system from severe hemorrhage.
    The journal of trauma and acute care surgery, 2021, 02-01, Volume: 90, Issue:2

    Topics: Animals; Apoptosis; Cardiovascular System; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens; Ethinyl Estradiol; Inflammation; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Receptors, Estrogen; Shock, Hemorrhagic; Signal Transduction; Swine; Treatment Outcome

2021
An estrogen (17α-ethinyl estradiol-3-sulfate) reduces mortality in a swine model of multiple injuries and hemorrhagic shock.
    The journal of trauma and acute care surgery, 2022, 01-01, Volume: 92, Issue:1

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Monitoring; Estrogens; Ethinyl Estradiol; Male; Multiple Trauma; Myocardial Contraction; Shock, Hemorrhagic; Survival Analysis; Swine; Treatment Outcome

2022