Page last updated: 2024-08-17

ethinyl estradiol and erythromycin

ethinyl estradiol has been researched along with erythromycin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's3 (12.00)18.2507
2000's7 (28.00)29.6817
2010's9 (36.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Dansette, PM; Fontana, E; Poli, SM1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Jaffe, P; Liberman, MM; McFadyen, I; Valman, HB1
Delaforge, M; Sartori, E1
Cunliffe, WJ1
Rajka, G1
Back, DJ; Orme, ML1
Adlercreutz, H; Hämäläinen, EK; Korpela, JT; Pulkkinen, MO1
Gerny, H1
Chandler, MH; Collins, D; Muse, KN; Sides, GD; Wermeling, DP1
Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC1
De Guise, S; Fortier, M; Fournier, M; Hammill, M; Kleinert, C; Lacaze, E1

Reviews

3 review(s) available for ethinyl estradiol and erythromycin

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
Acne vulgaris. The past. The present and the future.
    Acta dermato-venereologica. Supplementum, 1985, Volume: 120

    Topics: Acne Vulgaris; Androgen Antagonists; Androgens; Benzoyl Peroxide; Cyproterone; Cyproterone Acetate; Dermatitis, Seborrheic; Drug Combinations; Erythromycin; Ethinyl Estradiol; Female; Humans; Isotretinoin; Male; Propionibacterium acnes; Sebum; Tetracycline; Tretinoin

1985
Interactions between oral contraceptive steroids and broad-spectrum antibiotics.
    Clinical and experimental dermatology, 1986, Volume: 11, Issue:4

    Topics: Acne Vulgaris; Animals; Anti-Bacterial Agents; Contraceptives, Oral, Synthetic; Drug Interactions; Erythromycin; Ethinyl Estradiol; Female; Humans; Pregnancy; Tetracycline

1986

Trials

2 trial(s) available for ethinyl estradiol and erythromycin

ArticleYear
Studies on the role of intestinal bacteria in metabolism of synthetic and natural steroid hormones.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: Adult; Contraceptive Agents, Female; Erythromycin; Estradiol; Estrone; Ethinyl Estradiol; Feces; Female; Humans; Intestines; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Norethindrone; Oxytetracycline; Trimethoprim

1984
Dirithromycin increases ethinyl estradiol clearance without allowing ovulation.
    Obstetrics and gynecology, 1995, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Drug Combinations; Erythromycin; Ethinyl Estradiol; Female; Humans; Macrolides; Mestranol; Metabolic Clearance Rate; Norethindrone; Ovulation

1995

Other Studies

20 other study(ies) available for ethinyl estradiol and erythromycin

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Letter: Incidence of congenital limb-reduction deformities.
    Lancet (London, England), 1975, Mar-01, Volume: 1, Issue:7905

    Topics: Abnormalities, Drug-Induced; Arm; Benzyl Compounds; Birth Weight; Congenital Abnormalities; England; Erythromycin; Ethinyl Estradiol; Ethisterone; Ethylenediamines; Female; Fingers; Hallux Valgus; Humans; Infant, Newborn; Leg; Male; Maternal Age; Meclizine; Norethindrone; Pyridines; Pyridoxine; Seasons; Sulfamethoxazole; Tibia; Trimethoprim

1975
Specific drug binding to rat liver cytochrome P-450 isozymes induced by pregnenolone-16 alpha-carbonitrile and macrolide antibiotics. Implications for drug interactions.
    Chemico-biological interactions, 1990, Volume: 73, Issue:2-3

    Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Enzyme Induction; Ergotamine; Ergotamines; Erythromycin; Ethinyl Estradiol; Ethylmorphine; Ferricyanides; Isoenzymes; Male; Microsomes, Liver; Norethindrone; Prednisolone; Prednisone; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Spectrophotometry; Theophylline

1990
On therapeutic approaches to some special types of acne.
    Acta dermato-venereologica. Supplementum, 1985, Volume: 120

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Androgen Antagonists; Anti-Inflammatory Agents; Benzoyl Peroxide; Clindamycin; Cyproterone; Cyproterone Acetate; Diazepam; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Erythromycin; Ethinyl Estradiol; Female; Humans; Hydrocortisone; Male; Sulfamethoxazole; Tetracycline; Tretinoin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
[Experiences in dermatologic practice with combined external treatment of acne with benzoyl peroxide and erythromycin].
    Zeitschrift fur Hautkrankheiten, 1984, Jul-01, Volume: 59, Issue:13

    Topics: Acne Vulgaris; Adolescent; Adult; Androgen Antagonists; Benzoyl Peroxide; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Erythromycin; Ethinyl Estradiol; Female; Humans; Male; Peroxides; Tetracycline; Ultraviolet Therapy

1984
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Animals; Carbon Monoxide; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ethinyl Estradiol; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Protein Binding; Quinidine; Recombinant Proteins; Spodoptera; Substrate Specificity; Testosterone; Time Factors; Transfection; Warfarin

1995
T lymphocyte-proliferative responses of harbor seal (Phoca vitulina) peripheral blood mononuclear cells (PBMCs) exposed to pharmaceuticals in vitro.
    Marine pollution bulletin, 2018, Volume: 127

    Topics: Animals; Carbamazepine; Cell Proliferation; Erythromycin; Ethinyl Estradiol; Female; Leukocytes, Mononuclear; Male; Naproxen; Phoca; T-Lymphocytes; Water Pollutants, Chemical

2018