Page last updated: 2024-08-17

ethinyl estradiol and efavirenz

ethinyl estradiol has been researched along with efavirenz in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's5 (55.56)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Nightingale, SL1
Bumpus, NN; Hollenberg, PF1
Bertz, R; Eley, T; Garner, D; Krantz, K; Nettles, R; Persson, A; Sevinsky, H; Yones, C; Zhang, J1
Ahluwalia, J; Ananworanich, J; Chaithongwongwatthana, S; Gorowara, M; Kriengsinyot, R; Landolt, NK; Lange, JM; Phanuphak, N; Pinyakorn, S; Thammajaruk, N; Thongpaeng, P; Ubolyam, S1
Ahluwalia, J; Ananworanich, J; Chaithongwongwatthana, S; Cremers, S; Kerr, S; Landolt, NK; Lange, JM; Phanuphak, N; Pinyakorn, S; Thammajaruk, N; Thomas, T; Thongpaeng, P; Ubolyam, S1
Aweeka, F; Baker, P; Berzins, B; Cohn, SE; Coombs, R; Coughlin, K; Cramer, YS; Gingrich, D; Godfrey, C; Haas, DW; Moran, LE; Rosenkranz, SL; Scarsi, KK; Zorrilla, CD1
Chaturvedula, A; Cicali, B; Cristofoletti, R; Hoechel, J; Lingineni, K; Schmidt, S; Vozmediano, V; Wendl, T; Wiesinger, H1

Trials

2 trial(s) available for ethinyl estradiol and efavirenz

ArticleYear
Efavirenz, in contrast to nevirapine, is associated with unfavorable progesterone and antiretroviral levels when coadministered with combined oral contraceptives.
    Journal of acquired immune deficiency syndromes (1999), 2013, Apr-15, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptives, Oral, Synthetic; Cyclopropanes; Desogestrel; Drug Interactions; Ethinyl Estradiol; Female; HIV; HIV Infections; Humans; Logistic Models; Middle Aged; Nevirapine; Progesterone; Prospective Studies; Thailand; Young Adult

2013
Pharmacogenetic interactions between antiretroviral drugs and vaginally administered hormonal contraceptives.
    Pharmacogenetics and genomics, 2020, Volume: 30, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Contraceptive Agents, Female; Contraceptive Agents, Hormonal; Contraceptive Devices, Female; Cyclopropanes; Cytochrome P-450 CYP2B6; Desogestrel; Drug Interactions; Ethinyl Estradiol; Female; Genetic Association Studies; Genotype; HIV Infections; Humans; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Ritonavir; Vagina

2020

Other Studies

7 other study(ies) available for ethinyl estradiol and efavirenz

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
From the Food and Drug Administration.
    JAMA, 1998, Nov-04, Volume: 280, Issue:17

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptives, Postcoital; Cyclopropanes; Drug Approval; Ethinyl Estradiol; Humans; Levonorgestrel; Oxazines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration

1998
Investigation of the mechanisms underlying the differential effects of the K262R mutation of P450 2B6 on catalytic activity.
    Molecular pharmacology, 2008, Volume: 74, Issue:4

    Topics: Alkynes; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Benzphetamine; Binding Sites; Catalysis; Cyclopropanes; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Cytochromes b5; Escherichia coli; Ethinyl Estradiol; Humans; Kinetics; Molecular Structure; Mutation; NADPH-Ferrihemoprotein Reductase; Oxidants; Oxidoreductases, N-Demethylating; Protein Binding; Spectrophotometry, Ultraviolet; tert-Butylhydroperoxide

2008
The effect of efavirenz on the pharmacokinetics of an oral contraceptive containing ethinyl estradiol and norgestimate in healthy HIV-negative women.
    Antiviral therapy, 2011, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Area Under Curve; Benzoxazines; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Cyclopropanes; Drug Interactions; Estrogens; Ethinyl Estradiol; Female; Humans; Norgestrel; Reverse Transcriptase Inhibitors; Young Adult

2011
Significant decrease of ethinylestradiol with nevirapine, and of etonogestrel with efavirenz in HIV-positive women.
    Journal of acquired immune deficiency syndromes (1999), 2014, Jun-01, Volume: 66, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Contraceptive Agents, Female; Cyclopropanes; Desogestrel; Dose-Response Relationship, Drug; Drug Interactions; Ethinyl Estradiol; Female; HIV Infections; Humans; Nevirapine; Prospective Studies

2014
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.
    CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:1

    Topics: Adult; Alkynes; Benzoxazines; Body Mass Index; Carbamazepine; Clarithromycin; Computer Simulation; Contraceptives, Oral, Combined; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Humans; Itraconazole; Levonorgestrel; Models, Biological; Obesity; Rifampin; Sex Hormone-Binding Globulin

2021