Page last updated: 2024-08-17

ethinyl estradiol and cyclosporine

ethinyl estradiol has been researched along with cyclosporine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's5 (27.78)29.6817
2010's10 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Duane, WC; Eckfeldt, JH; Furne, J; Hillstrom, J; Levitt, MD1
Eckfeldt, J; Levitt, MD; Pieper-Bigelow, C1
Benet, LZ; Bornheim, LM; Correia, MA; Hanstein, WG; Jäger, W; Mahnke, A; Xue, L1
Haehner, T; Müller-Enoch, D; Refaie, MO1
Gore, E; Groothuis, GM; Olinga, P; Pennings, JL; Vatakuti, S1
Groothuis, GMM; Olinga, P; Pennings, JLA; Vatakuti, S1
Brauers, K; Coonen, MLJ; Jennen, D; Kleinjans, JCS; Olde Damink, SWM; Schaap, FG; Van den Hof, WFPM; van Herwijnen, M1
Gorelick, DA; Souder, JP1

Reviews

1 review(s) available for ethinyl estradiol and cyclosporine

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005

Other Studies

17 other study(ies) available for ethinyl estradiol and cyclosporine

ArticleYear
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
    Molecular pharmacology, 2003, Volume: 63, Issue:2

    Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection

2003
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Lack of benefit of ursodeoxycholic acid in drug-induced cholestasis in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 200, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Cholestasis; Cyclosporine; Ethinyl Estradiol; Male; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1992
Sensitivity of HPLC and conventional bilirubin measurements in the detection of early cholestasis.
    The Journal of laboratory and clinical medicine, 1995, Volume: 125, Issue:5

    Topics: Animals; Bile Ducts; Bilirubin; Cholestasis; Chromatography, High Pressure Liquid; Cyclosporine; Ethinyl Estradiol; Guinea Pigs; Ligation; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity

1995
Ethynylestradiol-mediated induction of hepatic CYP3A9 in female rats: implication for cyclosporine metabolism.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:12

    Topics: Actins; Animals; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethinyl Estradiol; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunosuppressive Agents; Liver; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats

1999
Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Antifungal Agents; Antimalarials; Catalysis; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Estrogen Antagonists; Ethinyl Estradiol; Flavanones; Hormone Antagonists; Humans; Immunosuppressive Agents; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Mifepristone; NADPH-Ferrihemoprotein Reductase; Phospholipids; Quinidine; Quinine; Tacrolimus

2004
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
    Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3

    Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis; Colchicine; Cyclosporine; Diethylnitrosamine; Drug-Related Side Effects and Adverse Reactions; Ethinyl Estradiol; Female; Gene Expression Profiling; Hepatocytes; Humans; Liver; Male; Methyltestosterone; Middle Aged; Necrosis; Phenotype; Toxicogenetics; Young Adult

2016
Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.
    Archives of toxicology, 2017, Volume: 91, Issue:3

    Topics: 1-Naphthylisothiocyanate; Aged; Chlorpromazine; Cholestasis; Cyclosporine; Dose-Response Relationship, Drug; Ethinyl Estradiol; Female; Gene Expression Profiling; Humans; Liver; Male; Methyltestosterone; Middle Aged; Signal Transduction; Transcriptome; Young Adult

2017
Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 44

    Topics: Animals; Bile Acids and Salts; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Cyclosporine; Ethinyl Estradiol; Hep G2 Cells; Hepatocytes; Humans; Liver; Mice; Transcriptome

2017
Assaying uptake of endocrine disruptor compounds in zebrafish embryos and larvae.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2018, Volume: 208

    Topics: Age Factors; Animals; ATP-Binding Cassette Transporters; Benzhydryl Compounds; Cyclosporine; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Endocrine Disruptors; Estradiol; Ethinyl Estradiol; Halogenated Diphenyl Ethers; Larva; Phenols; Time Factors; Water Pollutants, Chemical; Zebrafish; Zebrafish Proteins

2018