Page last updated: 2024-08-17

ethinyl estradiol and antipyrine

ethinyl estradiol has been researched along with antipyrine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Campillo, NE; Guerra, A; Páez, JA1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Branch, RA; Halliwell, M; Homeida, M1
Challiner, MR; Park, BK; Whittaker, AD1
Ehnholm, C; Heikkinen, JE; Luoma, PV; Ylöstalo, PR1
Back, DJ; Breckenridge, AM; Purba, HS1
Back, DJ; Maggs, JL; Newby, S; Park, BK; Purba, HS1
Back, DJ; Breckenridge, AM; Crawford, F; Cross, K; MacIver, M; Orme, ML; Rowe, PH; Smith, E1
Chambers, DM; Chambers, M; Jefferson, GC; Loudon, NB1
Back, DJ; Barkfeldt, JO; Breckenridge, AM; Odlind, V; Orme, M; Park, BK; Purba, H; Tjia, J; Victor, A1
Bartoli, A; Barzaghi, N; Cipolla, G; Fattore, C; Gatti, G; Mumford, J; Perucca, E; Veliz, G1

Trials

1 trial(s) available for ethinyl estradiol and antipyrine

ArticleYear
A double-blind, placebo-controlled study on the effect of vigabatrin on in vivo parameters of hepatic microsomal enzyme induction and on the kinetics of steroid oral contraceptives in healthy female volunteers.
    Epilepsia, 1997, Volume: 38, Issue:6

    Topics: Adult; Anticonvulsants; Antipyrine; Aryl Hydrocarbon Hydroxylases; Contraceptives, Oral, Combined; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Enzyme Induction; Estradiol Congeners; Ethinyl Estradiol; Female; gamma-Aminobutyric Acid; gamma-Glutamyltransferase; Half-Life; Humans; Levonorgestrel; Microsomes, Liver; Oxidoreductases, N-Demethylating; Placebos; Vigabatrin

1997

Other Studies

14 other study(ies) available for ethinyl estradiol and antipyrine

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of an oral contraceptive on hepatic size and antipyrine metabolism in premenopausal women.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Antipyrine; Contraceptives, Oral; Contraceptives, Oral, Combined; Ethinyl Estradiol; Female; Half-Life; Humans; Liver; Menopause; Norgestrel; Organ Size; Time Factors

1978
The effect of enzyme induction on the irreversible binding of ethynyloestradiol to guinea pig liver microsomes.
    Life sciences, 1978, Dec-18, Volume: 23, Issue:25

    Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Ethinyl Estradiol; Flavonoids; Guinea Pigs; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rifampin; Spironolactone

1978
One year study of effects of an oestrogen-dominant oral contraceptive on serum high-density lipoprotein cholesterol, apolipoproteins A-I and A-II and hepatic microsomal function.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:5

    Topics: Adult; Antipyrine; Apolipoproteins A; Cholesterol; Cholesterol, HDL; Contraceptives, Oral; Contraceptives, Oral, Sequential; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Metabolic Clearance Rate; Microsomes, Liver; Norgestrel; Triglycerides

1987
Inhibition of estrogen 2-hydroxylase.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:5

    Topics: Animals; Antipyrine; Chloroquine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Diethylstilbestrol; Estradiol; Ethinyl Estradiol; Imidazoles; Kinetics; Male; Metronidazole; Microsomes, Liver; Primaquine; Rats; Rats, Inbred Strains; Steroid Hydroxylases

1986
2-Hydroxylation of ethinyloestradiol in relation to the oxidation of sparteine and antipyrine.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:4

    Topics: Adult; Animals; Antipyrine; Ethinyl Estradiol; Humans; Hydroxylation; Male; Middle Aged; Oxidation-Reduction; Primaquine; Rats; Rats, Inbred Strains; Sparteine

1984
Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.
    Ciba Foundation symposium, 1980, Volume: 76

    Topics: Animals; Antipyrine; Contraceptives, Oral; Environment; Ethinyl Estradiol; Female; Half-Life; Humans; Intestinal Mucosa; Jejunum; Kinetics; Norethindrone; Norgestrel; Phenobarbital; Rats; Rifampin

1980
Antipyrine elimination in saliva after low-dose combined or progestogen-only oral contraceptive steroids.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Antipyrine; Contraceptives, Oral; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Ethinyl Estradiol; Female; Half-Life; Humans; Kinetics; Norgestrel; Saliva

1982
The enzyme inducing effect of rifampicin in the rhesus monkey and its lack of interaction with oral contraceptive steroids.
    Contraception, 1982, Volume: 25, Issue:3

    Topics: Animals; Antipyrine; Drug Interactions; Enzyme Induction; Ethinyl Estradiol; Female; Hydroxycholesterols; Macaca mulatta; Metabolic Clearance Rate; Microsomes, Liver; Norethindrone; Rifampin

1982