Page last updated: 2024-08-17

ethinyl estradiol and acetaminophen

ethinyl estradiol has been researched along with acetaminophen in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's1 (3.85)18.2507
2000's10 (38.46)29.6817
2010's10 (38.46)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bult, A; Halvax, JJ; Van Bennekom, WP; Wiese, G1
Back, DJ; Grimmer, SF; Orme, ML; Rogers, SM; Stevenson, PJ1
Back, DJ; Orme, ML; Rogers, SM1
Catania, VA; Luquita, MG; Mottino, AD; Ruiz, ML; Villanueva, SS; Vore, M1
Intravijit, J; Kibbey, TC; Lorphensri, O; Osathaphan, K; Sabatini, DA; Saiwan, C1
Kibbey, TC; Lorphensri, O; Osathaphan, K; Sabatini, DA; Saiwan, C1
Catania, VA; Ikushiro, S; Luquita, MG; Mottino, AD; Ruiz, ML; Villanueva, SS1
Gore, E; Groothuis, GM; Olinga, P; Pennings, JL; Vatakuti, S1
Belmonte, PRH; Cardoso, CSG; da Silva, JCGE; Mota, AAR; Oliveira, MACG; Santos, AJM1
Belini, AD; Bernardelli, JKB; Carvalho, KQ; Lima, MX; Marcelino, GR; Nagalli, A; Passig, FH1
Afonso, RJCF; Alves, MCP; Aquino, SF; Freitas, MG; Quaresma, AV; Sanson, AL1

Reviews

2 review(s) available for ethinyl estradiol and acetaminophen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005

Other Studies

24 other study(ies) available for ethinyl estradiol and acetaminophen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
On-line phase-transfer catalysed dansylation of phenolic compounds followed by normal-phase liquid chromatography with fluorescence detection.
    Journal of pharmaceutical and biomedical analysis, 1992, Volume: 10, Issue:5

    Topics: Acetaminophen; Chromatography, Liquid; Dansyl Compounds; Estradiol; Ethinyl Estradiol; Fluorescence

1992
Paracetamol interaction with oral contraceptive steroids: increased plasma concentrations of ethinyloestradiol.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:6

    Topics: Acetaminophen; Adult; Contraceptives, Oral, Hormonal; Drug Interactions; Ethinyl Estradiol; Female; Humans; Kinetics; Levonorgestrel; Norgestrel

1987
Intestinal metabolism of ethinyloestradiol and paracetamol in vitro: studies using Ussing chambers.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:6

    Topics: Acetaminophen; Chromatography, High Pressure Liquid; Ethinyl Estradiol; Humans; Ileum; In Vitro Techniques; Intestinal Mucosa; Jejunum; Membrane Potentials

1987
Ethynylestradiol increases expression and activity of rat liver MRP3.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:6

    Topics: Acetaminophen; Animals; ATP-Binding Cassette Transporters; Bile; Ethinyl Estradiol; Liver; Male; Multidrug Resistance-Associated Proteins; Perfusion; Rats; Rats, Wistar; Time Factors; Up-Regulation

2006
Sorption of acetaminophen, 17alpha-ethynyl estradiol, nalidixic acid, and norfloxacin to silica, alumina. and a hydrophobic medium.
    Water research, 2006, Volume: 40, Issue:7

    Topics: Acetaminophen; Adsorption; Aluminum Oxide; Analgesics, Non-Narcotic; Anti-Infective Agents; Bioreactors; Estrogens; Ethinyl Estradiol; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Nalidixic Acid; Norfloxacin; Silicon Dioxide

2006
Sorption and transport of acetaminophen, 17alpha-ethynyl estradiol, nalidixic acid with low organic content aquifer sand.
    Water research, 2007, Volume: 41, Issue:10

    Topics: Acetaminophen; Ethinyl Estradiol; Hydrogen-Ion Concentration; Kinetics; Models, Theoretical; Nalidixic Acid; Pharmaceutical Preparations; Sorption Detoxification; Water

2007
Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

    Topics: Acetaminophen; Animals; Anion Transport Proteins; Antiporters; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Cholestasis, Intrahepatic; Ethinyl Estradiol; Gene Expression; Glucuronosyltransferase; Glutathione; Liver; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organ Size; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SLC4A Proteins; Spironolactone; Up-Regulation

2007
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
    Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3

    Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis; Colchicine; Cyclosporine; Diethylnitrosamine; Drug-Related Side Effects and Adverse Reactions; Ethinyl Estradiol; Female; Gene Expression Profiling; Hepatocytes; Humans; Liver; Male; Methyltestosterone; Middle Aged; Necrosis; Phenotype; Toxicogenetics; Young Adult

2016
Fate and behaviour of acetaminophen, 17α-ethynylestradiol and carbamazepine in aqueous solution.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2020, Volume: 81, Issue:2

    Topics: Acetaminophen; Animals; Carbamazepine; Chlorine; Ethinyl Estradiol; Water Pollutants, Chemical

2020
Construction waste as substrate in vertical subsuperficial constructed wetlands treating organic matter, ibuprofenhene, acetaminophen and ethinylestradiol from low-strength synthetic wastewater.
    The Science of the total environment, 2020, Aug-01, Volume: 728

    Topics: Acetaminophen; Biodegradation, Environmental; Ethinyl Estradiol; Nitrogen; Phosphorus; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Wetlands

2020
Occurrence and removal of drugs and endocrine disruptors in water supply systems in the metropolitan region of Belo Horizonte (Minas Gerais State, Brazil).
    Environmental monitoring and assessment, 2022, Jun-03, Volume: 194, Issue:7

    Topics: Acetaminophen; Brazil; Dexamethasone; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estrone; Ethinyl Estradiol; Losartan; Sulfamethoxazole; Water Pollutants, Chemical; Water Supply

2022