Page last updated: 2024-08-21

ethidium bromide and camptothecin

ethidium bromide has been researched along with camptothecin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.76)29.6817
2010's18 (85.71)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Hranjec, M; Karminski-Zamola, G; Kralj, M; Pavelić, K; Piantanida, I; Suman, L1
Dong, G; Guo, Z; Miao, Z; Sheng, C; Wang, S; Yao, J; Zhang, W; Zhang, Y1
Banerjee, UC; Baviskar, AT; Das, D; Guchhait, SK; Kandekar, S; Kashyap, M; Kundu, CN; Mohapatra, P; Preet, R; Satapathy, SR; Siddharth, S1
Chang, IH; Jun, KY; Kwon, Y; Lee, E; Lee, ES; Na, Y; Park, SE1
Chen, SB; Gu, LQ; Huang, SL; Huang, ZS; Li, D; Mai, YW; Ou, TM; Tan, JH; Wang, HG; Xie, HT; Yao, BL; Yao, PF1
Amrutkar, S; Banerjee, UC; Guchhait, SK; Kundu, CN; Nayak, A; Priyadarshani, G1
Chang, YQ; Chen, WM; Hou, W; Jiang, RW; Lin, H; Lin, J; Liu, X; Peng, CK; Sun, PH; Wang, ZY; Xu, J1
Chang, YQ; Chen, WM; Hou, W; Lin, H; Lin, J; Lu, K; Peng, CK; Sun, PH; Xu, XJ; Zeng, T1
Dong, G; Fang, Y; Liu, N; Liu, Y; Sheng, C; Wu, S; Zhang, W1
Ajitha, A; Akunuri, R; Kamal, A; Kovvuri, J; Nagaraju, B; Nagesh, N; Nayak, VL; Rao, MPN1
Chowdhury, SR; Dhatchana Moorthy, N; Ganesan, K; Gunasekaran, K; Iqbal, S; Mageshwaran, T; Majumder, HK; Mohanakrishnan, AK; Muthu Ramalingam, B; Rajesh, BN; Saha, S; Siva, R; Vellaichamy, E1
Chen, HX; Dong, CZ; Du, ZY; Huang, ZS; Jiang, H; Li, PH; Li, YL; Tang, YD; Zhang, LY; Zhang, WJ; Zhao, MC; Zhou, W1
Chen, HX; Dong, CZ; Du, ZY; Jiang, H; Li, PH; Wang, J; Zhang, K; Zhang, WJ1
An, LK; Chen, JW; Gu, LQ; Huang, ZS; Yang, H; Yu, LM; Yu, Q; Zhu, TW1
Banwell, MG; Chen, WM; Hou, W; Lin, H; Lin, J; Sun, PH; Wang, ZY; Zeng, T1
Chen, H; Dong, C; Du, Z; Jiang, H; Li, P; Li, Y; Zhang, K; Zhang, W1
Agama, K; An, LK; Hu, DX; Kiselev, E; Marchand, C; Ofori-Atta, K; Pommier, Y; Ravji, A; Tang, WL; Wang, HW; Yang, H; Zhang, XR; Zhang, Y1
An, LK; Hao, XJ; Jin, LY; Khan, A; Liu, H; Liu, HY; Qin, XJ; Yan, H; Yu, Q1
Chen, NY; Mo, DL; Pan, CX; Su, GF; Wei, K; Wei, XW; Yuan, JM; Zhang, GH1
Che, T; Hu, DX; Li, D; Shu, B; Yu, Q; Zhang, SS1
Chen, S; Li, M; Meng, C; Wang, Y; Yin, X; Yuan, C1

Other Studies

21 other study(ies) available for ethidium bromide and camptothecin

ArticleYear
Novel amidino-substituted thienyl- and furylvinylbenzimidazole: derivatives and their photochemical conversion into corresponding diazacyclopenta[c]fluorenes. synthesis, interactions with DNA and RNA, and antitumor evaluation. 4.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; Circular Dichroism; DNA; DNA Topoisomerases, Type I; Fluorenes; Humans; Nucleic Acid Denaturation; Photochemistry; RNA; Spectrophotometry, Ultraviolet

2008
New tricks for an old natural product: discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure-activity relationship analysis and biological evaluations.
    Journal of medicinal chemistry, 2012, Sep-13, Volume: 55, Issue:17

    Topics: Antineoplastic Agents, Phytogenic; Biological Products; Cell Line, Tumor; Drug Screening Assays, Antitumor; Evodia; Humans; Quinazolines; Structure-Activity Relationship

2012
Indenoindolone derivatives as topoisomerase II-inhibiting anticancer agents.
    Bioorganic & medicinal chemistry letters, 2013, Feb-15, Volume: 23, Issue:4

    Topics: Antineoplastic Agents; DNA Topoisomerases, Type II; Humans; Indoles; Models, Molecular; Neoplasms; Topoisomerase II Inhibitors

2013
3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones

2013
Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Amines; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; K562 Cells; Molecular Structure; Phenazines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2015
Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Design; Flavonoids; Humans; Neoplasm Invasiveness; Pyrimidinones; Topoisomerase II Inhibitors

2016
Novel securinine derivatives as topoisomerase I based antitumor agents.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Antineoplastic Agents; Azepines; Cell Line, Tumor; Cell Proliferation; DNA Cleavage; DNA Topoisomerases, Type I; Drug Design; Heterocyclic Compounds, Bridged-Ring; Humans; Lactones; Models, Molecular; Piperidines; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors

2016
Novel 4-(4-substituted amidobenzyl)furan-2(5H)-one derivatives as topoisomerase I inhibitors.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Cleavage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Design; Furans; Humans; Molecular Docking Simulation; Nucleic Acid Conformation; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors

2017
Design, synthesis and evaluation of 4-substituted anthra[2,1-c][1,2,5]thiadiazole-6,11-dione derivatives as novel non-camptothecin topoisomerase I inhibitors.
    Bioorganic & medicinal chemistry letters, 2017, 05-01, Volume: 27, Issue:9

    Topics: Anthraquinones; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Drug Design; Humans; Molecular Docking Simulation; Neoplasms; Thiadiazoles; Topoisomerase I Inhibitors

2017
Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Antineoplastic Agents; Binding Sites; Carbolines; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Docking Simulation; Molecular Structure; Photosensitizing Agents; Structure-Activity Relationship; Topoisomerase I Inhibitors

2018
Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues.
    Journal of medicinal chemistry, 2018, 02-08, Volume: 61, Issue:3

    Topics: Carbazoles; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; DNA Damage; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Humans; Indole Alkaloids; Models, Molecular; Nucleic Acid Conformation; Oxygen; Topoisomerase II Inhibitors

2018
Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers.
    European journal of medicinal chemistry, 2018, Feb-10, Volume: 145

    Topics: Antineoplastic Agents; Apoptosis; Biocatalysis; Carbazoles; Cell Cycle Checkpoints; Cell Proliferation; Chalcone; DNA Cleavage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Molecular Structure; Plasmids; Structure-Activity Relationship; Topoisomerase II Inhibitors

2018
Synthesis and biological evaluation of novel carbazole-rhodanine conjugates as topoisomerase II inhibitors.
    Bioorganic & medicinal chemistry letters, 2018, 05-01, Volume: 28, Issue:8

    Topics: Antineoplastic Agents; Carbazoles; Cell Line, Tumor; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Etoposide; Humans; Intercalating Agents; Rhodanine; Topoisomerase II Inhibitors

2018
Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors.
    European journal of medicinal chemistry, 2018, May-25, Volume: 152

    Topics: Antineoplastic Agents; Biocatalysis; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indolizines; Molecular Structure; Quinolones; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2018
Novel bivalent securinine mimetics as topoisomerase I inhibitors.
    MedChemComm, 2017, Feb-01, Volume: 8, Issue:2

    Topics:

2017
Design, synthesis and biological evaluation of benzimidazole-rhodanine conjugates as potent topoisomerase II inhibitors.
    MedChemComm, 2018, Jul-01, Volume: 9, Issue:7

    Topics:

2018
Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
    Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; DNA Cleavage; DNA Topoisomerases, Type I; Drug Design; Humans; Models, Molecular; Phenanthridines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors

2018
Eucalypglobulusals A-J, Formyl-Phloroglucinol-Terpene Meroterpenoids from Eucalyptus globulus Fruits.
    Journal of natural products, 2018, 12-28, Volume: 81, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Eucalyptus; Fruit; Humans; Molecular Structure; Terpenes; Topoisomerase I Inhibitors

2018
Cryptolepine and aromathecin based mimics as potent G-quadruplex-binding, DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis.
    European journal of medicinal chemistry, 2019, May-01, Volume: 169

    Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Breaks, Double-Stranded; DNA Cleavage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; G-Quadruplexes; Heterocyclic Compounds, 4 or More Rings; Humans; Indole Alkaloids; Mice; Molecular Structure; Neoplasms, Experimental; Quinolines; Structure-Activity Relationship

2019
Synthesis and biological evaluation of novel indole-pyrazoline hybrid derivatives as potential topoisomerase 1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2020, 02-15, Volume: 30, Issue:4

    Topics: Binding Sites; DNA Topoisomerases, Type I; DNA, Superhelical; Drug Design; Humans; Indoles; Molecular Dynamics Simulation; Pyrazoles; Structure-Activity Relationship; Topoisomerase I Inhibitors

2020
Discovery, Topo I inhibitory activity and mechanism evaluation of two novel cytisine-type alkaloid dimers from the seeds of Sophora alopecuroides L.
    Bioorganic & medicinal chemistry, 2022, 05-01, Volume: 61

    Topics: Alkaloids; Azocines; Molecular Docking Simulation; Quinolizines; Seeds; Sophora

2022