Page last updated: 2024-08-21

ethambutol and clofazimine

ethambutol has been researched along with clofazimine in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19906 (8.82)18.7374
1990's32 (47.06)18.2507
2000's9 (13.24)29.6817
2010's18 (26.47)24.3611
2020's3 (4.41)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S1
Aínsa, JA; Martín, C; Ramón-García, S; Thompson, CJ1
Barry, CE; Dartois, V1
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P1
Boido, V; Cannas, S; Loddo, R; Molicotti, P; Novelli, F; Parapini, S; Sparatore, A; Sparatore, F; Tasso, B; Tonelli, M; Zanetti, S1
Centárová, I; Cole, ST; Čonka, P; Hrabálek, A; Karabanovich, G; Klimešová, V; Mikušová, K; Němeček, J; Pávek, P; Pávková, I; Roh, J; Šarkan, M; Smutný, T; Stolaříková, J; Székely, R; Vávrová, K; Vejsová, M; Vocat, A; Zemanová, J1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Sychra, P; Valášková, L; Vávrová, K; Vlčková, H1
Bera, S; Mondal, D1
Dušek, J; Hrabálek, A; Huszár, S; Jand'ourek, O; Karabanovich, G; Klimešová, V; Kočová Vlčková, H; Konečná, K; Konyariková, Z; Korábečný, J; Korduláková, J; Kučera, T; Mikušová, K; Pávek, P; Pávková, I; Pavliš, O; Roh, J; Savková, K; Stolaříková, J; Vávrová, K1
Cynamon, MH; DeStefano, MS; Klemens, SP1
Cynamon, MH; Klemens, SP; Swenson, CE1
Dautzenberg, B; Grosset, J; Katlama, C; Mignon, A; Parrot, R; Perronne, C; Rozenbaum, W; Truffot, C1
Bartok, AE; Chiu, J; Deresinski, SC; Feigal, DF; Kemper, CA; Leedom, JM; McCutchan, JA; Meng, TC; Nussbaum, J; Tilles, JG1
Benson, CA; Kessler, HA; Pottage, JC; Trenholme, GM1
Dwyer, B; Grayson, L; Hoy, J; Lucas, R; Mijch, A; Sandland, M1
Saito, H; Sato, K1
Blanche, S; Bodemer, C; De Prost, Y; Durand, C; Teillac, D1
Gharpuray, MB; Kulkarni, DS; Kulkarni, V1
Agins, BD; Berman, DS; el-Sadr, W; Rahal, JJ; Simberkoff, MS; Spicehandler, D1
Farhi, DC; Gangadharam, PR; Iseman, MD; Jairam, BT; Nguyen, AK; Perumal, VK; Rao, PN1
Nash, DR; Steele, LC; Steingrube, V; Wallace, RJ1
De Micco, P; Gevaudan, MJ1
Dekio, S; Hidaka, T; Kawahara, S; Saito, H; Sato, K; Tomioka, H1
Gordin, FM; Sullam, PM; Wynne, BA1
Dautzenberg, B; Olliaro, P1
Bartok, AE; Dubé, M; Haghighat, D; Havlir, D; Kemper, CA; Leedom, JM; Sison, JP; Tilles, JG; Yangco, B; Yao, Y1
Bartok, AE; Camp, B; Deresinski, SC; Havlir, D; Kane, C; Kemper, CA; Lane, N1
Bryskier, A; Goh, KS; Rastogi, N1
Andreoli, A; Kohn, A; Luzi, C; Mangiarotti, R; Prantera, C1
Gordon, SM; Havlik, JA; Heifets, L; Horsburgh, CR; McGowan, JE; Metchock, B; Peloquin, CA; Thompson, SE1
Brummer, E; Deresinski, SC; Hamilton, JR; Kemper, CA; Sison, JP; Stevens, DA; Yao, Y2
Fanning, MM; Fong, IW; Gill, MJ; Lalonde, RG; Phillips, P; Rachlis, AR; Salit, I; Shafran, SD; Singer, J; Tsoukas, CM; Walmsley, SL; Zarowny, DP1
Carosi, GP; Dautzenberg, B; Esposito, R; Hoy, JF; L'Age, M; Micoud, M; Olliaro, P; Opravil, M; Pirotta, N; Rozenbaum, W; Ruf, B; Sassella, D1
Coker, RJ; Fisher, M; Tomlinson, DR1
Bryskier, A; Devallois, A; Goh, KS; Rastogi, N1
Benson, CA; Chaisson, RE; Craft, JC; Fessel, WJ; Keiser, P; Lahart, C; Meek, K; Pierce, M; Ruskin, J; Siepman, N1
Beuscart, C; Brel, F; Dautzenberg, B; Doco-Lecompte, T; Grosset, J; May, T; Perronne, C; Saint-Marc, T; Vincent, V1
Butts, JD; Faris, MA; Hopfer, RL; Raasch, RH1
Barber, TW; Currier, J; Ellner, JJ; Hafner, R; Hojczyk, P; Hooton, TM; Jacobs, MR; Limjoco, M; Parenti, DM; Powderly, WG; Simpson, G; van der Horst, C; Williams, PL1
Dubé, MP; Havlir, DV; Kemper, CA; Leedom, JM; McCutchan, JA; Sattler, FR; See, D; Tilles, JG; Torriani, FJ1
Burguière, AM; Eliaszewicz, M; Flahault, A; Fournier, S; Treilhou, MP; Vincent, V1
Khorasheh, S; Lemieux, C; Raboud, JM; Salit, I; Shafran, SD; Singer, J; Thorne, A; Tsoukas, CM; Wu, AW1
Cheng, B1
Prescott, LM1
Currier, J1
Cocco, MT; Congiu, C; De Logu, A; Onnis, V; Saddi, B; Schivo, ML1
Cowie, RL; Field, SK1
Janulionis, E; Sofer, C; Song, HY; Wallis, RS1
Chimara, E; da Silva Telles, MA; Ferrazoli, L; Riley, LW1
Agnihotri, SP; Gupta, P; Gupta, S; Jain, NK; Sharma, KK1
Hassan, G; Kant, S; Parengal, J; Saheer, S1
Chiang, CY; Madan, J; Meredith, SK; Nunn, AJ; Phillips, PP; Rusen, ID; Squire, SB; Torrea, G; Van Deun, A1
Boukary, I; Daouda, M; Hanki, Y; Harouna, SH; Morou, S; Piubello, A; Souleymane, MB; Van Deun, A1
Abena Foe, JL; Aït-Khaled, N; Kuaban, C; Noeske, J; Rieder, HL; Trébucq, A1
Cowie, RL; Davis, JP; Field, SK; Fisher, DA; Jarand, J1
Adamson, J; Almeida, DV; Ammerman, NC; Bester, LA; Dorasamy, A; Grosset, JH; Mgaga, Z; Moodley, C; Moodley, S; Ngcobo, B; Singh, SD; Swanson, RV1
Chande, N; MacDonald, JK; Parker, CE; Patton, PH1
Blackmore, T; McNaughton, A; McNaughton, H1
Cao, P; Doan, TN; Emeto, TI; McBryde, ES; McCaw, JM1
Ding, X; Fan, G; Ho, CM; Jiang, J; Lan, L; Lou, Y; Wu, S1
Chaudhary, S; Garg, V; Maji, S; Singh, V1
Ahmad, N; Atif, M; Ghafoor, A; Iqbal, Q; Khan, S; Latif, A; Saleem, F; Wahid, A1
Anderson, R; Cholo, MC; Mashele, SA; Matjokotja, MT; Rasehlo, SSM; Steel, HC1

Reviews

4 review(s) available for ethambutol and clofazimine

ArticleYear
A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Lung; Mycobacterium tuberculosis; Tuberculosis

2013
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Treatment and prophylaxis of disseminated Mycobacterium avium complex in HIV-infected individuals.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: 4-Quinolones; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clofazimine; Ethambutol; Humans; Macrolides; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifamycins

1998
Anti-tuberculous therapy for maintenance of remission in Crohn's disease.
    The Cochrane database of systematic reviews, 2016, Jul-22, Volume: 7

    Topics: Antitubercular Agents; Clarithromycin; Clofazimine; Crohn Disease; Ethambutol; Glucocorticoids; Humans; Maintenance Chemotherapy; Methylprednisolone; Prednisone; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Rifabutin; Rifampin; Secondary Prevention

2016

Trials

18 trial(s) available for ethambutol and clofazimine

ArticleYear
Rifabutin in combination with clofazimine, isoniazid and ethambutol in the treatment of AIDS patients with infections due to opportunist mycobacteria. Groupe d'Etude et de Traitement des Infections à Mycobacteries Résistantes.
    Tubercle, 1991, Volume: 72, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antitubercular Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Mycobacterium Infections; Opportunistic Infections; Prospective Studies; Rifabutin; Rifamycins

1991
Treatment of Mycobacterium avium complex bacteremia in AIDS with a four-drug oral regimen. Rifampin, ethambutol, clofazimine, and ciprofloxacin. The California Collaborative Treatment Group.
    Annals of internal medicine, 1992, Mar-15, Volume: 116, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Amikacin; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Clofazimine; Colony Count, Microbial; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Prospective Studies; Rifampin

1992
Efficacy of rifabutin in the treatment of disseminated infection due to Mycobacterium avium complex. The Rifabutin Treatment Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 19, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Bacteremia; Clofazimine; Ethambutol; Humans; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Prospective Studies; Rifabutin

1994
Control of the body burden of M. avium complex is associated with improved quality of life and prolonged survival of patients with AIDS: a prospective trial with rifabutin combined with isoniazid, clofazimine, ethambutol.
    Journal of chemotherapy (Florence, Italy), 1994, Volume: 6, Issue:3

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Body Burden; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Prospective Studies; Quality of Life; Rifabutin

1994
The individual microbiologic effect of three antimycobacterial agents, clofazimine, ethambutol, and rifampin, on Mycobacterium avium complex bacteremia in patients with AIDS.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:1

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Bacteremia; Clofazimine; Ethambutol; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium avium-intracellulare Infection; Rifampin

1994
Transient bacteremia due to Mycobacterium avium complex in patients with AIDS.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Bacteremia; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Life Tables; Mycobacterium avium-intracellulare Infection; Prospective Studies; Recurrence; Rifampin; Risk Factors; Survival Analysis

1994
Antimycobacterial therapy in Crohn's disease: results of a controlled, double-blind trial with a multiple antibiotic regimen.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Antitubercular Agents; Clofazimine; Crohn Disease; Dapsone; Double-Blind Method; Drug Therapy, Combination; Ethambutol; Female; Humans; Male; Mycobacterium Infections, Nontuberculous; Prospective Studies; Rifampin; Time Factors

1994
Treatment of Mycobacterium avium complex infection: do the results of in vitro susceptibility tests predict therapeutic outcome in humans?
    The Journal of infectious diseases, 1996, Volume: 173, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antitubercular Agents; Bacteremia; Clofazimine; Ethambutol; Humans; In Vitro Techniques; Macrophages; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifampin

1996
Treatment of Myocardium avium complex infection: does the beige mouse model predict therapeutic outcome in humans?
    The Journal of infectious diseases, 1996, Volume: 173, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Animals; Antitubercular Agents; Clofazimine; Colony Count, Microbial; Disease Models, Animal; Ethambutol; Humans; Liver; Mice; Mycobacterium avium-intracellulare Infection; Rifampin; Species Specificity; Spleen

1996
A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group.
    The New England journal of medicine, 1996, Aug-08, Volume: 335, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antitubercular Agents; Bacteremia; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; Female; Humans; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifampin; Survival Analysis; Treatment Outcome; Uveitis

1996
Rifabutin versus placebo in combination with three drugs in the treatment of nontuberculous mycobacterial infection in patients with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antitubercular Agents; Clofazimine; Double-Blind Method; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Mycobacterium Infections; Placebos; Rifabutin

1996
Clarithromycin and ethambutol with or without clofazimine for the treatment of bacteremic Mycobacterium avium complex disease in patients with HIV infection.
    AIDS (London, England), 1997, Volume: 11, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Male; Mycobacterium avium-intracellulare Infection

1997
Comparison of combination therapy regimens for treatment of human immunodeficiency virus-infected patients with disseminated bacteremia due to Mycobacterium avium. ANRS Trial 033 Curavium Group. Agence Nationale de Recherche sur le Sida.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Bacteremia; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; Female; Humans; Male; Mycobacterium avium-intracellulare Infection; Prospective Studies; Recurrence; Rifabutin

1997
A phase II/III trial of antimicrobial therapy with or without amikacin in the treatment of disseminated Mycobacterium avium infection in HIV-infected individuals. AIDS Clinical Trials Group Protocol 135 Study Team.
    AIDS (London, England), 1998, Dec-24, Volume: 12, Issue:18

    Topics: Adult; AIDS-Related Opportunistic Infections; Amikacin; Bacteremia; Ciprofloxacin; Clofazimine; Colony Count, Microbial; Drug Therapy, Combination; Ethambutol; Female; Humans; Male; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifampin

1998
Successful short-term suppression of clarithromycin-resistant Mycobacterium avium complex bacteremia in AIDS. California Collaborative Treatment Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 28, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Bacteremia; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin

1999
Effect of adding clofazimine to combined clarithromycin-ethambutol therapy for Mycobacterium avium complex septicemia in AIDS patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1999, Volume: 18, Issue:1

    Topics: Aged; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal; Bacteremia; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; Female; Humans; Male; Middle Aged; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Survival Analysis

1999
Symptomatic and health status outcomes in the Canadian randomized MAC treatment trial (CTN010). Canadian HIV Trials Network Protocol 010 Study Group.
    International journal of STD & AIDS, 2000, Volume: 11, Issue:4

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Bacteremia; Canada; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; Health Status; Humans; Mycobacterium avium-intracellulare Infection; Outcome and Process Assessment, Health Care; Rifabutin; Rifampin; Treatment Outcome

2000
Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial.
    Trials, 2014, Sep-09, Volume: 15

    Topics: Antitubercular Agents; Bangladesh; Clinical Protocols; Clofazimine; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Moxifloxacin; Prothionamide; Pyrazinamide; Research Design; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2014

Other Studies

46 other study(ies) available for ethambutol and clofazimine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen

2007
Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Antitubercular Agents; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Clofazimine; Dithiothreitol; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Glutathione; Hydrogen Peroxide; Membrane Transport Proteins; Mutation; Mycobacterium tuberculosis; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rifampin; Valinomycin

2009
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines.
    Bioorganic & medicinal chemistry, 2014, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Antitubercular Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Humans; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Phenazines; Pyrrolidines; Quinolizidines; Structure-Activity Relationship; Tuberculosis; Vero Cells

2014
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Animals; Antitubercular Agents; Bacteria; Cell Line; Cell Survival; Drug Design; Drug Resistance, Multiple, Bacterial; Fungi; Humans; Latent Tuberculosis; Microbial Sensitivity Tests; Microsomes; Mutagens; Mycobacterium tuberculosis; Oxazoles; Primary Cell Culture; Rifampin; Structure-Activity Relationship; Thiadiazoles

2016
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents.
    European journal of medicinal chemistry, 2017, Jan-27, Volume: 126

    Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles

2017
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Antitubercular Agents; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Solubility; Structure-Activity Relationship; Tetrazoles; Water

2017
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Alcohol Oxidoreductases; Antitubercular Agents; Bacterial Proteins; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Development; Hydrocarbons, Fluorinated; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles

2019
Activity of clarithromycin against Mycobacterium avium complex infection in beige mice.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Amikacin; Animals; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Clofazimine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Humans; Mice; Mice, Inbred C57BL; Mycobacterium avium; Mycobacterium avium Complex; Quinolones; Rifabutin; Rifampin; Rifamycins; Time Factors; Tuberculosis

1992
TLC G-65 in combination with other agents in the therapy of Mycobacterium avium infection in beige mice.
    The Journal of antimicrobial chemotherapy, 1992, Volume: 29, Issue:6

    Topics: Amikacin; Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Culture Media; Drug Therapy, Combination; Erythromycin; Ethambutol; Gentamicins; Liposomes; Mice; Mice, Inbred C57BL; Mycobacterium avium; Rifampin; Tuberculosis

1992
Successful treatment of acquired immunodeficiency syndrome-related Mycobacterium avium complex disease with a multiple drug regimen including amikacin.
    Archives of internal medicine, 1991, Volume: 151, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amikacin; Antitubercular Agents; Ciprofloxacin; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Rifampin

1991
Quadruple-drug therapy for Mycobacterium avium-intracellulare bacteremia in AIDS patients.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Infective Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifamycins; Sepsis

1990
Activity of rifabutin alone and in combination with clofazimine, kanamycin and ethambutol against Mycobacterium intracellulare infections in mice.
    Tubercle, 1989, Volume: 70, Issue:3

    Topics: Animals; Antitubercular Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Female; Kanamycin; Liver; Lung; Mice; Mice, Inbred C57BL; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifamycins; Spleen

1989
[Disseminated Mycobacterium marinum infection].
    Annales de dermatologie et de venereologie, 1989, Volume: 116, Issue:11

    Topics: Child, Preschool; Clofazimine; Consanguinity; Drug Therapy, Combination; Ethambutol; Female; Hepatomegaly; Humans; Immunity, Cellular; Joint Diseases; Mycobacterium Infections; Rifampin; Skin Diseases; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Multiple cold abscesses in a borderline lepromatous patient on multidrug therapy.
    Indian journal of leprosy, 1989, Volume: 61, Issue:4

    Topics: Abscess; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Ethambutol; Hip Joint; Humans; Isoniazid; Leprosy, Borderline; Leprosy, Lepromatous; Male; Rifampin; Tuberculosis, Osteoarticular

1989
Effect of combined therapy with ansamycin, clofazimine, ethambutol, and isoniazid for Mycobacterium avium infection in patients with AIDS.
    The Journal of infectious diseases, 1989, Volume: 159, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Anti-Bacterial Agents; Antitubercular Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Lactams, Macrocyclic; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Respiratory Tract Infections; Retrospective Studies; Sepsis

1989
Activity of rifabutin alone or in combination with clofazimine or ethambutol or both against acute and chronic experimental Mycobacterium intracellulare infections.
    The American review of respiratory disease, 1987, Volume: 136, Issue:2

    Topics: Animals; Chronic Disease; Clofazimine; Drug Therapy, Combination; Ethambutol; Male; Mice; Mice, Inbred C57BL; Mycobacterium avium; Rifabutin; Rifamycins; Tuberculosis

1987
Susceptibility testing of slowly growing mycobacteria by a microdilution MIC method with 7H9 broth.
    Journal of clinical microbiology, 1986, Volume: 24, Issue:6

    Topics: Anti-Bacterial Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Mycobacterium tuberculosis; Nontuberculous Mycobacteria; Rifampin; Streptomycin; Sulfamethoxazole

1986
[Extra and intracellular activity of dirithromycin against Mycobacterium avium].
    Pathologie-biologie, 1995, Volume: 43, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Clofazimine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythromycin; Ethambutol; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macrolides; Macrophages; Mycobacterium avium; Rifabutin

1995
Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice.
    Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1995, Volume: 76, Issue:1

    Topics: Animals; Antitubercular Agents; Clarithromycin; Clofazimine; Drug Synergism; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Ofloxacin; Quinolones; Rifamycins; Streptomycin

1995
Activities of roxithromycin used alone and in combination with ethambutol, rifampin, amikacin, ofloxacin, and clofazimine against Mycobacterium avium complex.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6

    Topics: Amikacin; Clofazimine; Drug Synergism; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Ofloxacin; Rifampin; Roxithromycin

1994
Low serum levels of oral antimycobacterial agents in patients with disseminated Mycobacterium avium complex disease.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Ciprofloxacin; Clofazimine; Drug Monitoring; Ethambutol; Female; Humans; Male; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Prospective Studies; Rifampin

1993
The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group.
    International journal of STD & AIDS, 1996, Volume: 7, Issue:4

    Topics: Adrenal Cortex Hormones; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; HIV Infections; Humans; Isoniazid; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Nontuberculous Mycobacteria; Practice Guidelines as Topic; Pyrazinamide; Pyridoxine; Radiography; Rifabutin; Rifampin; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

1996
Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:11

    Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Clofazimine; Drug Combinations; Ethambutol; Humans; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium Complex; Ofloxacin; Rifampin; Roxithromycin

1996
Advances in prevention and treatment of MAC.
    PI perspective, 1995, Issue:no 17

    Topics: AIDS-Related Opportunistic Infections; Azithromycin; CD4 Lymphocyte Count; Clarithromycin; Clinical Trials as Topic; Clofazimine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethambutol; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifampin

1995
Macrolides, azalides, and streptogrammins.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacteremia; Bacterial Infections; Clarithromycin; Clofazimine; Cryptosporidiosis; Drug Therapy, Combination; Duodenal Ulcer; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium-intracellulare Infection; Pneumonia; Smoking; Virginiamycin

1996
Progress report: prophylaxis and therapy for MAC.
    AIDS clinical care, 1996, Volume: 8, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Antitubercular Agents; Azithromycin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin

1996
Pot shots.
    Notes from the underground (New York, N.Y.), 1996, Issue:No 33

    Topics: Acetylcysteine; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Agents; Antiviral Agents; Cattle; CD4 Lymphocyte Count; China; Clarithromycin; Clinical Trials as Topic; Clofazimine; Cryptosporidiosis; Drug Combinations; Ethambutol; Expectorants; Glutathione; Hepatitis B; Humans; Immunoglobulins; Interferon-alpha; Italy; Leprostatic Agents; Mycobacterium avium-intracellulare Infection; Philippines; Protease Inhibitors; Survival Rate; Taiwan; Thymosin; Zidovudine

1996
MAC management.
    PI perspective, 1996, Issue:No 20

    Topics: Acquired Immunodeficiency Syndrome; Amikacin; Antitubercular Agents; Ciprofloxacin; Clarithromycin; Clofazimine; Drug Interactions; Drug Therapy, Combination; Ethambutol; Humans; Mycobacterium avium-intracellulare Infection; Rifabutin; Rifampin; Tuberculin Test; Zidovudine

1996
Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis.
    The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:2

    Topics: Aminosalicylic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Chlorocebus aethiops; Clofazimine; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Ethambutol; Humans; Hydrazones; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Vero Cells

2002
Treatment of Mycobacterium avium-intracellulare complex lung disease with a macrolide, ethambutol, and clofazimine.
    Chest, 2003, Volume: 124, Issue:4

    Topics: Aged; Aged, 80 and over; Antitubercular Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Female; Humans; Leprostatic Agents; Lung Diseases; Macrolides; Male; Middle Aged; Mycobacterium avium-intracellulare Infection

2003
Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8

    Topics: Anti-Infective Agents; Antitubercular Agents; Area Under Curve; Blood; Cells, Cultured; Clofazimine; Colony Count, Microbial; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Serum Bactericidal Test

2004
Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates.
    Journal of medical microbiology, 2005, Volume: 54, Issue:Pt 10

    Topics: Amikacin; Anti-Bacterial Agents; Brazil; Ciprofloxacin; Clarithromycin; Clofazimine; Cycloserine; DNA Fingerprinting; DNA, Bacterial; Doxycycline; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rifabutin; Rifampin; Streptomycin

2005
Extensively drug resistance (XDR) tb is not always fatal.
    The Indian journal of tuberculosis, 2009, Volume: 56, Issue:1

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Aza Compounds; Capreomycin; Clarithromycin; Clofazimine; Drug Therapy, Combination; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; India; Injections; Male; Moxifloxacin; Quinolines; Sputum; Treatment Outcome

2009
Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
    BMJ case reports, 2012, May-08, Volume: 2012

    Topics: Adult; Antitubercular Agents; Clarithromycin; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; HIV Seronegativity; Humans; Isoniazid; Kanamycin; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant

2012
High cure rate with standardised short-course multidrug-resistant tuberculosis treatment in Niger: no relapses.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2014, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Aged; Body Mass Index; Body Weight; Clofazimine; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Fluoroquinolones; Follow-Up Studies; Gatifloxacin; HIV Infections; Humans; Kanamycin; Male; Middle Aged; Niger; Prospective Studies; Pyrazinamide; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2014
High effectiveness of a 12-month regimen for MDR-TB patients in Cameroon.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Cameroon; Clofazimine; Cohort Studies; Confidence Intervals; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Kanamycin; Male; Medication Adherence; Middle Aged; Odds Ratio; Prospective Studies; Prothionamide; Pyrazinamide; Risk Assessment; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2015
Long-term Follow-up of Mycobacterium avium Complex Lung Disease in Patients Treated With Regimens Including Clofazimine and/or Rifampin.
    Chest, 2016, Volume: 149, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clofazimine; Drug Therapy, Combination; Ethambutol; Female; Follow-Up Studies; Humans; Macrolides; Male; Middle Aged; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Pneumonia; Retrospective Studies; Rifampin

2016
Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5

    Topics: Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethambutol; Female; Isoniazid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis; Withholding Treatment

2016
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand.
    The European respiratory journal, 2016, Volume: 48, Issue:4

    Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Clofazimine; Depression; Drug Costs; Emigrants and Immigrants; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Health Care Costs; Humans; India; Isoniazid; Linezolid; Male; Mediastinum; Microbial Sensitivity Tests; Moxifloxacin; New Zealand; Pyrazinamide; Radiography, Thoracic; Rifampin; Schizophrenia, Paranoid; Tuberculosis, Lymph Node; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pleural; Tuberculosis, Pulmonary

2016
Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:12

    Topics: Antitubercular Agents; Clofazimine; Colony Count, Microbial; Computer Simulation; Diarylquinolines; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Bacterial; Drug Therapy, Combination; Ethambutol; Host-Pathogen Interactions; Humans; Immunity, Innate; Isoniazid; Kanamycin; Macrophages; Microbial Sensitivity Tests; Models, Statistical; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Prothionamide; Pyrazinamide; Time Factors; Tuberculosis, Multidrug-Resistant

2018
Simultaneous determination of the potent anti-tuberculosis regimen-Pyrazinamide, ethambutol, protionamide, clofazimine in beagle dog plasma using LC-MS/MS method coupled with 96-well format plate.
    Journal of pharmaceutical and biomedical analysis, 2019, May-10, Volume: 168

    Topics: Animals; Antitubercular Agents; Calibration; Chromatography, Liquid; Clofazimine; Dogs; Ethambutol; Prothionamide; Pyrazinamide; Reproducibility of Results; Tandem Mass Spectrometry

2019
Isolated multidrug-resistant tubercular tenosynovitis of the flexor tendon of the little finger.
    BMJ case reports, 2021, Feb-19, Volume: 14, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antitubercular Agents; Clofazimine; Cycloserine; Diagnosis, Differential; Drug Resistance, Multiple; Ethambutol; Female; Fingers; Humans; Levofloxacin; Linezolid; Magnetic Resonance Imaging; Tendons; Tenosynovitis; Tuberculosis; Young Adult

2021
Effectiveness of Shorter Treatment Regimen in Multidrug-Resistant Tuberculosis Patients in Pakistan: A Multicenter Retrospective Record Review.
    The American journal of tropical medicine and hygiene, 2021, 03-15, Volume: 104, Issue:5

    Topics: Adult; Amikacin; Antitubercular Agents; Clofazimine; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; Humans; Isoniazid; Lost to Follow-Up; Male; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Pakistan; Pyrazinamide; Retrospective Studies; Survival Analysis; Treatment Failure; Tuberculosis, Multidrug-Resistant

2021
Assessment of the efficacy of clofazimine alone and in combination with primary agents against Mycobacterium tuberculosis in vitro.
    Journal of global antimicrobial resistance, 2022, Volume: 29

    Topics: Animals; Antitubercular Agents; Clofazimine; Ethambutol; Humans; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis

2022