ethacrynic acid and ticrynafen

ethacrynic acid has been researched along with ticrynafen in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agnew, MN; Caldwell, SR; Kitzen, JM; Ong, HH; Profitt, JA; Ress, RJ; Tegeler, JJ; Wilker, JC1
Bunnell, PR; Crowley, SR; Dodge, PW; Fung, AK; Pariza, RJ; Parks, JA; Pernet, AG; Plattner, JJ1
Allen, RC; Försch, MF; Setescak, LL; Shutske, GM; Wilker, JC1
Allen, RC; Davis, L; Effland, RC; Kitzen, JM; Novick, WJ; Ranbom, K; Setescak, LL; Shutske, GM; Wilker, JC1
Board, PG; Christ, AN; Clark, AG; Flanagan, JU; Hall, R; Hayes, JD; Hume, DA; Oakley, AJ; Smythe, ML; Weber, JE1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Maass, AR; Snow, IB1
el Masry, S; Gray, PD; Janicki, RS; Luther, RR; Tolman, KG1
Bretz, NS; Budd, GC; Koechel, DA1
Ahokas, JT; Davies, C; Emmerson, BT; Ravenscroft, PJ1
Mutschler, E; Steinbach, D; Stüber, W1
Herbinger, W1
Alvarado, JA; Epstein, DL; Franse-Carman, L; Ichikawa, M; Rao, PV; Shimazaki, A1

Reviews

1 review(s) available for ethacrynic acid and ticrynafen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for ethacrynic acid and ticrynafen

ArticleYear
[(6,7-Dichlorobenzo[b]thien-5-yl)oxy]acetic acids and 1,1-dioxides. 1. A structurally novel class of diuretics with hypotensive activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:12

    Topics: Acetates; Animals; Antihypertensive Agents; Diuretics; Dogs; Female; Glycolates; Male; Mice; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Structure-Activity Relationship; Thiophenes

1987
Substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazole-6-carboxylic acids: high-ceiling diuretics with uricosuric activity.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:8

    Topics: Animals; Chlorides; Diuretics; Dogs; Dose-Response Relationship, Drug; Furans; Haplorhini; Isoxazoles; Mice; Models, Molecular; Natriuresis; Oxazoles; Potassium; Rats; Sodium; Stereoisomerism; Structure-Activity Relationship; Uricosuric Agents

1984
Heterocyclic oxyacetic acid diuretics: indazole, benzisothiazole, and benzisothiazole 1,1-dioxide analogues of [[7-chloro-3-(2-fluorophenyl)-1,2-benzisoxazol-6-yl]oxy]acetic acid.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:9

    Topics: Animals; Diuretics; Dogs; Isoxazoles; Mice; Natriuresis; Oxazoles

1983
[(3-aryl-1,2-benzisoxazol-6-yl)oxy]acetic acids. A new diuretic series.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:1

    Topics: Animals; Diuretics; Dogs; Isoxazoles; Male; Mice; Oxazoles; Structure-Activity Relationship; Uricosuric Agents

1982
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:2

    Topics: Binding Sites; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutathione Transferase; Hematopoiesis; Humans; Intramolecular Oxidoreductases; Lipocalins; Models, Molecular; Molecular Conformation; Nocodazole

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Renal pharmacology of tienilic acid.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Acid-Base Imbalance; Animals; Diuresis; Dogs; Ethacrynic Acid; Female; Glycolates; Kidney; Kidney Tubules; Natriuresis; p-Aminohippuric Acid; Ticrynafen; Water-Electrolyte Imbalance

1979
Toxicity of uricosuric diuretics in rat hepatocyte culture.
    Biochemical pharmacology, 1989, Apr-01, Volume: 38, Issue:7

    Topics: Animals; Benzene Derivatives; Cells, Cultured; Diuretics; Drug Evaluation, Preclinical; Ethacrynic Acid; Glycolates; Indans; Liver; Male; Models, Biological; Rats; Rats, Inbred Strains; Ticrynafen; Uricosuric Agents

1989
Acute effects of alkylating agents on canine renal function and ultrastructure: high-dose ethacrynic acid vs. dihydroethacrynic acid and ticrynafen.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3

    Topics: Animals; Dogs; Ethacrynic Acid; Female; Glomerular Filtration Rate; Glycolates; Kidney; Kidney Tubules, Proximal; Male; Proteinuria; Renal Circulation; Ticrynafen

1984
Inhibition of soluble glutathione S-transferase by diuretic drugs.
    Biochemical pharmacology, 1984, Jun-15, Volume: 33, Issue:12

    Topics: Animals; Diuretics; Ethacrynic Acid; Glutathione Transferase; Liver; Male; Rats; Rats, Inbred Strains; Solubility; Structure-Activity Relationship; Ticrynafen

1984
Determination of ethacrynic and tienilic acid in plasma by gas--liquid chromatography--mass spectrometry.
    Journal of chromatography, 1982, Jan-08, Volume: 227, Issue:1

    Topics: Ethacrynic Acid; Gas Chromatography-Mass Spectrometry; Glycolates; Humans; Ticrynafen

1982
[Diuretics in the therapy of chronic cardiac insufficiency].
    Wiener medizinische Wochenschrift (1946), 1982, Oct-15, Volume: 132, Issue:19

    Topics: Acetazolamide; Amiloride; Diuretics; Drug Interactions; Ethacrynic Acid; Heart Failure; Humans; Indapamide; Metolazone; Risk; Spironolactone; Sulfonamides; Thiazoles; Ticrynafen; Triamterene

1982
Effects of novel ethacrynic acid derivatives on human trabecular meshwork cell shape, actin cytoskeletal organization, and transcellular fluid flow.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:12

    Topics: Actins; Aqueous Humor; Cell Culture Techniques; Cell Shape; Cell Survival; Cinnamates; Cytoskeleton; Diuretics; Drug Evaluation, Preclinical; Ethacrynic Acid; Focal Adhesions; Humans; Intraocular Pressure; Ocular Hypotension; Sclera; Ticrynafen; Trabecular Meshwork

2005