ethacrynic acid has been researched along with probenecid in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (64.29) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Beyer, KH; Bohn, DL; Fanelli, GM; Scriabine, A | 1 |
| Czazkes, W; Gutman, Y; Wald, H | 1 |
| Clifton, G; Kaplowitz, N; Wallin, JD | 1 |
| Czaczkes, W; Gutman, Y; Wald, H | 1 |
| Frederiksen, A; Heinemann, HO; Wagner, M | 1 |
| Braun, W; Damm, KH | 1 |
| al-Awqati, Q; Hedrich, R; Landry, DW; Marten, I; Redhead, C; Zeilinger, C | 1 |
| Bonet Domingo, E; García Alvarez-Coque, MC; Medina Hernández, MJ; Ramis Ramos, G | 1 |
| Rybak, LP; Scott, V; Whitworth, C | 1 |
| Madshus, IH; Olsnes, S | 1 |
| Damm, KH; Woermann, C | 1 |
| Christiansen, PA; Frederick, PK; Reiser, S | 1 |
| Bárány, EH | 1 |
| Almeida, AF; Charnock, JS | 1 |
| Ina, K; Ito, M; Suzuki, Y; Yamagami, I | 1 |
| Foulkes, EC; Nolan, RP | 1 |
| Kürten, M; Vogel, G | 1 |
| Cafruny, EJ; Gussin, RZ | 1 |
| Binder, HJ; Katz, LA; Spencer, RP; Spiro, HM | 1 |
| Bartholomew, TC; Billing, BH; Corbett, CL; Summerfield, JA | 1 |
| KUNIN, CM | 1 |
2 review(s) available for ethacrynic acid and probenecid
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
26 other study(ies) available for ethacrynic acid and probenecid
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Saluretic and uricosuric effects of (6, 7-dichloro-2-methyl=1-oxo-2-phenyl-5-indanyloxy) acetic acid (MK-196) in the chimpanzee.
Topics: Animals; Diuresis; Drug Interactions; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Indans; Indenes; Male; Mersalyl; p-Aminohippuric Acid; Pan troglodytes; Potassium; Probenecid; Rats; Sodium Chloride; Stimulation, Chemical; Time Factors; Uric Acid; Uricosuric Agents | 1977 |
Differences in characteristics of ethacrynic acid accumulation in kidney cortex, medulla and papilla.
Topics: Animals; Ethacrynic Acid; Ethylmaleimide; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Medulla; Male; Ouabain; Probenecid; Rats; Time Factors | 1975 |
The effect of phenobarbital, probenecid and diethyl maleate on the pharmaco-kinetics and biliary excretion of ethacrynic acid in the rat.
Topics: Animals; Bile; Cytosol; Ethacrynic Acid; Glutathione Transferase; Kidney; Kinetics; Liver; Male; Maleates; Metabolic Clearance Rate; Phenobarbital; Probenecid; Protein Binding; Rats | 1978 |
Ethacrynic acid influx and efflux in kidney cortex slices: dependence on sodium gradient.
Topics: Animals; Depression, Chemical; Ethacrynic Acid; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Ouabain; Probenecid; Rats; Sodium; Time Factors | 1978 |
Palmitic acid utilization by the renal cortex of the rat.
Topics: Adipose Tissue; Animals; Carbon Dioxide; Ethacrynic Acid; Fatty Acids, Nonesterified; Female; Kidney Cortex; Liver; Lung; Myocardium; Oligomycins; Organomercury Compounds; Ouabain; Oxidation-Reduction; Palmitic Acids; Probenecid; Rats; Sodium; Time Factors | 1975 |
Drug interactions in intestinal absorption of 3H-digitoxin in rats.
Topics: Animals; Digitoxin; Ethacrynic Acid; Intestinal Absorption; Intestine, Small; Kidney; Liver; Male; Mersalyl; Muscles; Organomercury Compounds; Probenecid; Rats | 1976 |
Identification and modulation of a voltage-dependent anion channel in the plasma membrane of guard cells by high-affinity ligands.
Topics: Benzoates; Benzoic Acid; Blotting, Western; Cell Membrane; Ethacrynic Acid; Fabaceae; Glycolates; Ion Channels; Membrane Potentials; Membrane Proteins; Niflumic Acid; Nitrobenzoates; Plants, Medicinal; Probenecid; Protoplasts | 1992 |
High-performance liquid chromatographic determination of diuretics in urine by micellar liquid chromatography.
Topics: Acetazolamide; Bendroflumethiazide; Chlorothiazide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Micelles; Probenecid; Sodium Dodecyl Sulfate | 1992 |
Organic acids do not alter the cochlear effects of ethacrynic acid.
Topics: Action Potentials; Animals; Aspirin; Chinchilla; Cochlea; Ethacrynic Acid; Female; Male; Penicillin G; Probenecid | 1990 |
Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells.
Topics: Animals; Bicarbonates; Biological Transport, Active; Carrier Proteins; Chloride-Bicarbonate Antiporters; Chlorides; Ethacrynic Acid; Kinetics; Probenecid; Pyridoxal Phosphate; Sodium; Vero Cells | 1987 |
The effect of probenecid on the in vitro absorption of cardiac glycosides.
Topics: Animals; Biological Transport; Body Water; Calcium; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Ethacrynic Acid; Furosemide; Glucose; Hydrochlorothiazide; In Vitro Techniques; Intestinal Absorption; Jejunum; Mersalyl; Mice; Mice, Inbred Strains; Osmolar Concentration; Ouabain; Oxygen Consumption; Potassium; Probenecid; Sodium; Tritium | 1974 |
Effect of inhibitors on sodium-independent lysine transport in intact intestine.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Dinitrophenols; Ethacrynic Acid; Ethylmaleimide; Fluorides; In Vitro Techniques; Intestine, Small; Leucine; Lysine; Male; Probenecid; Rats; Sodium | 1973 |
The liver-like anion transport system in rabbit kidney, uvea and choroid plexus. I. Selectivity of some inhibitors, direction of transport, possible physiological substrates.
Topics: Animals; Bile; Biological Transport; Cephaloridine; Choroid Plexus; Depression, Chemical; Ethacrynic Acid; Female; Furosemide; Hippurates; Humans; In Vitro Techniques; Iodipamide; Iodohippuric Acid; Iopanoic Acid; Kidney Cortex; Male; Phenolphthaleins; Probenecid; Rabbits; Uvea | 1973 |
Ethacrynic acid accumulation by renal tissue.
Topics: Aerobiosis; Animals; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Ethacrynic Acid; Extracellular Space; Glucose; In Vitro Techniques; Kidney; Liver; Mannitol; Microscopy, Electron; Mitochondrial Swelling; Nitrogen; Nitrophenols; Ouabain; Oxygen; Probenecid; Rabbits; Temperature | 1972 |
[Pharmacological studies of diuretics. 4. Changes of serum uric acid level by the succesive administration of thiazide diuretics and other drugs and effects of uricosuric drugs].
Topics: Administration, Oral; Allopurinol; Ammonium Chloride; Animals; Barbiturates; Blood Glucose; Chlorothiazide; Cyclohexanes; Diuretics; Electrolytes; Ethacrynic Acid; Glycine; Hydrochlorothiazide; Hydroflumethiazide; Injections, Subcutaneous; Male; Nucleosides; Phenylbutazone; Probenecid; Quinolines; Rats; Sulfinpyrazone; Sulfonamides; Thiadiazines; Uric Acid; Uricosuric Agents; Xanthenes | 1971 |
Studies on renal urate secretion in the dog.
Topics: Aminohippuric Acids; Animals; Carbon Isotopes; Chlormerodrin; Chlorothiazide; Dogs; Ethacrynic Acid; Female; Furosemide; Inulin; Kidney; Lactates; Male; Probenecid; Pyrazines; Renal Artery; Time Factors; Tritium; Uric Acid | 1971 |
[Studies on the Na+ -dependency of renal tubular urea secretion in Rana ridibunda].
Topics: Alkaloids; Aminohippuric Acids; Animals; Anura; Biological Transport, Active; Depression, Chemical; Ethacrynic Acid; Furosemide; Glucose; In Vitro Techniques; Kidney Tubules; Organomercury Compounds; Perfusion; Plants, Medicinal; Probenecid; Sodium; Urea | 1967 |
Renal sites of action of ethacrynic acid.
Topics: Animals; Diuresis; Dogs; Ethacrynic Acid; Kidney Tubules; Mannitol; Potassium; Probenecid | 1966 |
The effect of inhibitors of renal transport on the small intestine.
Topics: Animals; Biological Transport; Chlorothiazide; Cricetinae; Ethacrynic Acid; Glucose; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Lysine; Methionine; Probenecid; Uracil | 1966 |
Urinary excretion of bile acids in cholestasis: evidence for renal tubular secretion in man.
Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Ethacrynic Acid; Female; Furosemide; Glycocholic Acid; Humans; Kidney Tubules; Male; Metabolic Clearance Rate; Middle Aged; Probenecid | 1981 |
INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS.
Topics: Acetazolamide; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Aspirin; Benzoates; Biguanides; Blood Proteins; Carbon Isotopes; Chlorothiazide; Diuretics; Ethacrynic Acid; Guanidines; Oxazoles; p-Aminohippuric Acid; Penicillin G; Penicillin V; Penicillins; Pharmacology; Phenylbutazone; Probenecid; Rabbits; Research; Salicylates; Sulfinpyrazone; Sulfonamides; Tolbutamide | 1965 |