ethacrynic acid and indomethacin

ethacrynic acid has been researched along with indomethacin in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199013 (38.24)18.7374
1990's7 (20.59)18.2507
2000's4 (11.76)29.6817
2010's10 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Board, PG; Christ, AN; Clark, AG; Flanagan, JU; Hall, R; Hayes, JD; Hume, DA; Oakley, AJ; Smythe, ML; Weber, JE1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cheung, CC; Fung, KP; Lai, PB; Lee, WY; Liu, KW; Wong, J; Yeung, JH1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Das Gupta, V; Ghanekar, AG; Gibbs, CW1
Jarabak, J; Lin, YM1
Bourland, WA; Farley, DB; Marchand, GR; Van Orden, DE; Williamson, HE1
Hart, M; Stone, KJ1
Granley, K; Jang, Y; Mishra, U; Singh, AK1
Bugge, JF; Kiil, F; Stokke, ES; Vikse, A1
Fujii, Y; Hayaishi, O; Hayashi, H; Watanabe, K1
Elías, MM; Rodriguez, JV; Torres, AM1
Bugge, JF; Kiil, F; Stokke, ES1
Goppelt-Strübe, M; Kaever, V; Resch, K1
Bourland, WA; Marchand, GR; Williamson, HE1
Jacoby, HI; Marshall, CH1
Finkelstein, RA; Goth, A; Lexomboon, U1
Hartmann, A; Kiil, F; Langberg, H; Vikse, A1
Ahrens, FA; Zhu, B1
Kern, F; Mallory, A1
Nakamura, S; Nomura, T; Ryoyama, K1
Henderson, GB; Hughes, TR; Saxena, M1
Berman, JD; Brendle, J; Middleton, W; Ray, P1
Fayz, S; Inaba, T1
Chew, M; Mack, P; Wong, KP; Yang, EB; Zhang, K1
Christoffers, J; Joachim, A; Lautscham, E; Ruttkowski, B1

Reviews

3 review(s) available for ethacrynic acid and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced pancreatitis: a critical review.
    Gastroenterology, 1980, Volume: 78, Issue:4

    Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Cholestyramine Resin; Cimetidine; Cyproheptadine; Dextropropoxyphene; Diazoxide; Diuretics; Estrogens; Ethacrynic Acid; Furosemide; Histamine; Humans; Hypercalcemia; Indomethacin; Isoniazid; Mercaptopurine; Narcotics; Pancreatitis; Phenformin; Procainamide; Rifampin; Salicylates; Sodium Chloride Symporter Inhibitors; Sulfonamides; Tetracycline

1980

Other Studies

31 other study(ies) available for ethacrynic acid and indomethacin

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:2

    Topics: Binding Sites; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutathione Transferase; Hematopoiesis; Humans; Intramolecular Oxidoreductases; Lipocalins; Models, Molecular; Molecular Conformation; Nocodazole

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells.
    Journal of natural products, 2010, May-28, Volume: 73, Issue:5

    Topics: Abietanes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Doxorubicin; Drug Resistance, Neoplasm; Humans; Models, Biological; Molecular Structure; Phenanthrenes; Plants, Medicinal; Salvia miltiorrhiza

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Stability of pediatric liquid dosage forms of ethacrynic acid, indomethacin, methyldopate hydrochloride, prednisone and spironolactone.
    American journal of hospital pharmacy, 1978, Volume: 35, Issue:11

    Topics: Child; Drug Compounding; Drug Stability; Ethacrynic Acid; Humans; Indomethacin; Methyldopa; Pharmaceutical Vehicles; Prednisone; Solutions; Spironolactone; Suspensions

1978
Isolation of two proteins with 9-ketoprostaglandin reductase and NADP-linked 15-hydroxyprostaglandin dehydrogenase activities and studies on their inhibition.
    Biochemical and biophysical research communications, 1978, Apr-28, Volume: 81, Issue:4

    Topics: Ethacrynic Acid; Female; Furosemide; Humans; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Placenta; Pregnancy

1978
Ethacrynic acid induced release of prostaglandin E to increase renal blood flow.
    Prostaglandins, 1976, Volume: 11, Issue:3

    Topics: Animals; Dogs; Ethacrynic Acid; Indomethacin; Kidney; Male; Prostaglandins E; Regional Blood Flow; Stimulation, Chemical

1976
Inhibition of renal PGE2-9-ketoreductase by diuretics.
    Prostaglandins, 1976, Volume: 12, Issue:2

    Topics: Alcohol Oxidoreductases; Animals; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydralazine; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Kidney Cortex; Phentolamine; Prostaglandins E; Rabbits; Rats; Thiazines

1976
Simultaneous analysis of flunixin, naproxen, ethacrynic acid, indomethacin, phenylbutazone, mefenamic acid and thiosalicylic acid in plasma and urine by high-performance liquid chromatography and gas chromatography-mass spectrometry.
    Journal of chromatography, 1991, Aug-23, Volume: 568, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Chromatography, High Pressure Liquid; Clonixin; Ethacrynic Acid; Gas Chromatography-Mass Spectrometry; Horses; Indomethacin; Mefenamic Acid; Naproxen; Phenylbutazone; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Thimerosal

1991
Stimulation of renin release by PGE2 and PGI2 infusion in the dog: enhancing effect of ureteral occlusion or administration of ethacrynic acid.
    Acta physiologica Scandinavica, 1990, Volume: 138, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epoprostenol; Ethacrynic Acid; Female; Indomethacin; Infusions, Intra-Arterial; Kidney; Male; Renal Circulation; Renin; Ureteral Obstruction

1990
Enzymatic formation of prostaglandin F2 alpha in human brain.
    Neurochemical research, 1990, Volume: 15, Issue:4

    Topics: Amino Acids; Binding Sites; Brain; Catalysis; Dinoprost; Dinoprostone; Ethacrynic Acid; Humans; Hydrogen-Ion Concentration; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Isoelectric Point; Molecular Weight; NADP; Phenanthrenes; Prostaglandins; Substrate Specificity; Triazines; Vitamin K

1990
Vulnerability of the thick ascending limb to glutathione depletion in rat kidney: effects of diuretics and indomethacin.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Animals; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Glutathione; In Vitro Techniques; Indomethacin; Kidney; Kidney Tubules; Loop of Henle; Male; Maleates; Rats; Rats, Inbred Strains

1989
Properties of the macula densa mechanism for renin release in the dog.
    Acta physiologica Scandinavica, 1988, Volume: 132, Issue:3

    Topics: Acetazolamide; Animals; Denervation; Dogs; Ethacrynic Acid; Female; Glomerular Filtration Rate; Homeostasis; Indomethacin; Isoproterenol; Kidney Tubules; Kidney Tubules, Distal; Male; Renal Artery; Renal Circulation; Renin; Ureter; Vascular Resistance

1988
Enhancement of eicosanoid synthesis in mouse peritoneal macrophages by the organic mercury compound thimerosal.
    Prostaglandins, 1988, Volume: 35, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Chromatography, High Pressure Liquid; Ethacrynic Acid; Ethylmercury Compounds; Female; Indomethacin; Macrophages; Masoprocol; Mice; Mice, Inbred Strains; Prostaglandins; Radioimmunoassay; SRS-A; Thimerosal; Thromboxanes

1988
Inhibition of ethacrynic acid induced increase in renal blood flow by indomethacin.
    Prostaglandins, 1974, Nov-25, Volume: 8, Issue:4

    Topics: Animals; Depression, Chemical; Dogs; Ethacrynic Acid; Female; Indomethacin; Kidney; Male; Regional Blood Flow; Stimulation, Chemical; Time Factors

1974
Antagonism of cholera enterotoxin by anti-inflammatory agents in the rat.
    Nature, 1972, Jan-21, Volume: 235, Issue:5334

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Body Weight; Cholera; Dexamethasone; Disease Models, Animal; Enterotoxins; Ethacrynic Acid; Female; Indomethacin; Injections, Subcutaneous; Phenylbutazone; Prednisolone; Rats; Rats, Inbred Strains; Sodium Salicylate

1972
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:2

    Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone

1971
Glomerulotubular balance and prostaglandin synthesis.
    Renal physiology, 1984, Volume: 7, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dogs; Ethacrynic Acid; Female; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Indomethacin; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Natriuresis; Prostaglandins; Renal Circulation; Water-Electrolyte Balance

1984
Effects of indomethacin, acetazolamide, ethacrynate sodium, and atropine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin in pig jejunum.
    Canadian journal of physiology and pharmacology, 1982, Volume: 60, Issue:10

    Topics: Acetazolamide; Animals; Atropine; Diarrhea; Enterotoxins; Escherichia coli; Ethacrynic Acid; Indomethacin; Intestinal Mucosa; Jejunum; Swine

1982
Inhibition of macrophage nitric oxide production by arachidonate-cascade inhibitors.
    Cancer immunology, immunotherapy : CII, 1993, Volume: 37, Issue:6

    Topics: Acetophenones; Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Caffeic Acids; Dexamethasone; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione Transferase; Indomethacin; Ketoconazole; Lipoxygenase; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Phospholipases A; Phospholipases A2; Sodium Nitrite; Umbelliferones

1993
Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells.
    Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1

    Topics: Biological Transport; Cells, Cultured; Cholic Acid; Cholic Acids; Dinitrochlorobenzene; Ethacrynic Acid; Hematopoietic Stem Cells; Humans; Indomethacin; Lymphocytes; Methotrexate; Prostaglandins A

1995
Botulinum toxin inhibits arachidonic acid release associated with acetylcholine release from PC12 cells.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Acetophenones; Acetylcholine; Animals; Arachidonic Acid; Botulinum Toxins; Cell Differentiation; Dose-Response Relationship, Drug; Ethacrynic Acid; Indomethacin; Kinetics; Masoprocol; Melitten; Models, Biological; Nerve Growth Factors; PC12 Cells; Phospholipases A; Phospholipases A2; Potassium; Protein Kinase C; Quinacrine; Terpenes

1993
Zidovudine azido-reductase in human liver microsomes: activation by ethacrynic acid, dipyridamole, and indomethacin and inhibition by human immunodeficiency virus protease inhibitors.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:7

    Topics: Chromatography, Thin Layer; Dipyridamole; Enzyme Activation; Enzyme Inhibitors; Enzyme Repression; Ethacrynic Acid; Humans; Indomethacin; Microsomes, Liver; Oxidoreductases; Zidovudine

1998
Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Biological Transport; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Carrier Proteins; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Hydrolyzable Tannins; Indomethacin; Membrane Transport Proteins; Oxidation-Reduction; Quercetin; Tumor Cells, Cultured

2001
Oesophagostomum dentatum: effect of glutathione S-transferase (GST) inhibitors on GST activity and larval development.
    Experimental parasitology, 2011, Volume: 127, Issue:4

    Topics: Animals; Biological Assay; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethacrynic Acid; Female; Glutathione Transferase; Hydrocortisone; Indomethacin; Inhibitory Concentration 50; Intestine, Large; Intramolecular Oxidoreductases; Larva; Lipocalins; Male; Oesophagostomum; Piperidines; Sulfobromophthalein; Swine; Temperature

2011