Compounds > ethacrynic acid

ethacrynic acid and dinitrochlorobenzene

ethacrynic acid has been researched along with dinitrochlorobenzene in 57 studies

*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]

*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19906 (10.53)18.7374
1990's27 (47.37)18.2507
2000's19 (33.33)29.6817
2010's5 (8.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baell, JB; Board, PG; Casarotto, MG; Dahlin, JL; Oakley, AJ; Xie, Y1
Inaba, T; Takamatsu, Y2
Watkins, JB1
Inoue, H; Kong, KH; Takahashi, K2
Mantle, TJ; Phillips, MF1
Lei, SB; Peng, RX1
Ploemen, JH; van Bladeren, PJ; van Ommen, B1
Awasthi, YC; Gupta, S; Leal, T; Medh, RD1
Aceto, A; Columbano, A; Di Ilio, C; Federici, G; Ledda-Columbano, GM1
Cochrane, BJ; LeBlanc, GA2
Jaffe, JJ; Lambert, RA1
Awasthi, YC; Singh, SV; Srivastava, SK1
Kaplowitz, N; Yamada, T1
Coban, T; Eke, BC; Iscan, M3
LaFollette, JW; Sanders, RA; Watkins, JB1
Dauterman, WC; Egaas, E; Falls, JG1
Henderson, GB; Hughes, TR; Saxena, M2
Buetler, TM; Eaton, DL; Van Ness, KP1
Bowie, A; Brennan, P; O'Neill, LA1
Bogaards, JJ; Jansen, DH; Ploemen, JH; van Bladeren, PJ; van Ommen, B; Veldink, GA1
Kohli, KK; Puri, S1
Dai, H; Edens, FW; Roe, RM1
Battistoni, A; Lo Bello, M; Mazzarese, G; Mazzetti, AP; Nuccetelli, M; Oakley, AJ; Parker, MW; Ricci, G; Rossjohn, J1
Anderson, K; Andrews, R; Grant, MH; Hayes, JD; MacDonald, C; McLeod, R; Yin, L1
Bammler, TK; Eaton, DL; McHugh, TE; Van Ness, KP1
Aimoto, T; Imai, K; Inoue, N1
Allardyce, CS; Lian, LY; McDonagh, PD; Roberts, GC; Wolf, CR1
Kulkarni, AP; Sajan, M1
Alves, MV; Bastos, JC; Camacho, L; Cunha Bastos, VL; Felzenszwalb, I1
Ketterman, AJ; Koottathep, S; Prapanthadara, L; Promtet, N; Somboon, P1
Di Giulio, RT; Gardinali, PR; Lienesch, LA; Willett, KL1
Antonini, G; Caccuri, AM; Federici, G; Lo Bello, M; Mazzetti, AP; McKinstry, WJ; Micaloni, C; Nuccetelli, M; Oakley, AJ; Parker, MW; Ricci, G; Rossjohn, J1
Girard, JP; Gnassia-Barelli, M; Hoarau, P; Romeo, M1
Habdous, M; Siest, G; Vincent-Viry, M; Visvikis, S1
Boersma, MG; Cnubben, NH; Rietjens, IM; Spenkelink, B; Usta, M; van Bladeren, PJ; van der Velde, AE; van Zanden, JJ; Wortelboer, HM1
Nauen, R; Rauch, N1
Li, EQ; Yang, HL; Zeng, QY; Zhou, XW; Zhu, SG1
Kirikbakan, A; Sen, A1
Gupta, S; Rathaur, S1
Donham, RT; Jewell, WT; Lamé, MW; Morin, D; Segall, HJ; Tjeerdema, RS1
Donham, RT; Morin, D; Tjeerdema, RS1
Semiz, A; Sen, A1
Doneanu, C; Gallagher, E; Gallis, B; Goodlett, D; Shaffer, S; Trute, M1
Seyfried, J; Wüllner, U1
Ahn, IY; Cheon, J; Kim, M; Park, H1
Setlíková, I; Wiegand, C1
Gold-Bouchot, G; Richardson, KL; Schlenk, D1
Arbildi, P; Chalar, C; Fernandez, C; Fernandez, V; García, G; Harispe, L; Pascovich, L; Zaha, A1
Bunderson, BR; Coulombe, RA; Croasdell, A; Kim, JE; Reed, KM1
Bunderson, BR; Coulombe, RA; Croasdell, A; Kim, JE; Mendoza, KM; Reed, KM1
Alparslan, MM; Danış, Ö1

Reviews

1 review(s) available for ethacrynic acid and dinitrochlorobenzene

ArticleYear
Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example.
    Journal of medicinal chemistry, 2018, 09-13, Volume: 61, Issue:17

    Topics: Drug Design; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescence Polarization; Glutathione Transferase; Humans

2018

Other Studies

56 other study(ies) available for ethacrynic acid and dinitrochlorobenzene

ArticleYear
Inhibition of human hepatic glutathione S-transferase isozymes by ethacrynic acid and its metabolites.
    Toxicology letters, 1992, Volume: 62, Issue:2-3

    Topics: Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Liver

1992
Effect of microsomal enzyme inducing agents on hepatic biotransformation in cotton rats (Sigmodon hispidus): comparison to that in Sprague-Dawley rats.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 98, Issue:2-3

    Topics: Animals; Arylsulfotransferase; Biotransformation; Cytochrome P-450 Enzyme System; Dinitrochlorobenzene; Enzyme Induction; Ethacrynic Acid; Female; Glucuronosyltransferase; Glutathione Transferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Sulfobromophthalein; Sulfotransferases

1991
Non-essentiality of cysteine and histidine residues for the activity of human class PI glutathione S-transferase.
    Biochemical and biophysical research communications, 1991, Dec-16, Volume: 181, Issue:2

    Topics: Base Sequence; Cysteine; Dinitrochlorobenzene; DNA; Escherichia coli; Ethacrynic Acid; Glutathione Transferase; Histidine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Structure-Activity Relationship; Transfection

1991
The initial-rate kinetics of mouse glutathione S-transferase YfYf. Evidence for an allosteric site for ethacrynic acid.
    The Biochemical journal, 1991, May-01, Volume: 275 ( Pt 3)

    Topics: Allosteric Site; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cattle; Computer Simulation; Dinitrochlorobenzene; Enzyme Activation; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Isoelectric Point; Kinetics; Male; Mice; Molecular Sequence Data; Rats; Sequence Homology, Nucleic Acid

1991
[Subcellular distribution of glutathione S-transferase in Chinese fetal liver].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:5

    Topics: Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Fetus; Glutathione Transferase; Humans; Liver; Microsomes, Liver; Nitrobenzenes; Substrate Specificity

1990
Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate.
    Biochemical pharmacology, 1990, Oct-01, Volume: 40, Issue:7

    Topics: Animals; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Male; Rats; Rats, Inbred Strains

1990
Selective expression of the three classes of glutathione S-transferase isoenzymes in mouse tissues.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Animals; Blotting, Western; Brain; Dinitrochlorobenzene; Ethacrynic Acid; Female; Gene Expression; Glutathione Peroxidase; Glutathione Transferase; Isoelectric Focusing; Isoenzymes; Kidney; Liver; Mice; Mice, Inbred Strains; Muscles; Myocardium; Spleen; Sulfobromophthalein

1990
Induction of rat liver glutathione transferase subunit 7 by lead nitrate.
    Cancer letters, 1989, Volume: 46, Issue:3

    Topics: Animals; Blotting, Western; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethacrynic Acid; Glutathione Transferase; Lead; Liver; Male; Nitrates; Rats; Rats, Inbred Strains

1989
Modulation of substrate-specific glutathione S-transferase activity in Daphnia magna with concomitant effects on toxicity tolerance.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 82, Issue:1

    Topics: Animals; Daphnia; Dinitrochlorobenzene; Enzyme Induction; Epoxy Compounds; Ethacrynic Acid; Glutathione Transferase; Nitrobenzenes; Nitrophenols; Pentachlorophenol; Substrate Specificity

1985
Genetics of xenobiotic metabolism in Drosophila. I. Genetic and environmental factors affecting glutathione-S-transferase in larvae.
    Biochemical pharmacology, 1986, May-15, Volume: 35, Issue:10

    Topics: Benzene Derivatives; Chromosome Mapping; Dinitrochlorobenzene; Drosophila melanogaster; Ethacrynic Acid; Glutathione Transferase; Hydrogen-Ion Concentration; Isoenzymes; Larva; Substrate Specificity

1986
Glutathione S-transferase in adult Dirofilaria immitis and Brugia pahangi.
    Molecular and biochemical parasitology, 1986, Volume: 20, Issue:2

    Topics: Animals; Brugia; Chromatography, Affinity; Dinitrochlorobenzene; Dirofilaria immitis; Electrophoresis, Polyacrylamide Gel; Ethacrynic Acid; Female; Filarioidea; Glutathione Transferase; Microsomes, Liver; Molecular Weight; Nitrobenzenes; Rats; Rats, Inbred Strains

1986
Effect of 3,5-di-t-butyl-4-hydroxytoluene (BHT) on glutathione-linked detoxification mechanisms of rat ocular lens.
    Experimental eye research, 1985, Volume: 41, Issue:3

    Topics: Animals; Butylated Hydroxytoluene; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione Peroxidase; Glutathione Transferase; Isoenzymes; Lens, Crystalline; Male; Nitrobenzenes; Rats; Rats, Inbred Strains

1985
Propylthiouracil. A substrate for the glutathione S-transferases that competes with glutathione.
    The Journal of biological chemistry, 1980, Apr-25, Volume: 255, Issue:8

    Topics: Animals; Binding, Competitive; Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Kinetics; Liver; Male; Propylthiouracil; Protein Binding; Rats; Spectrophotometry, Ultraviolet; Substrate Specificity

1980
Differential responses of hepatic monooxygenases and glutathione S-transferases of mice to a combination of cadmium and nickel.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 111, Issue:1

    Topics: Aniline Hydroxylase; Animals; Cadmium; Cytochrome P-450 Enzyme System; Cytochromes b5; Dinitrochlorobenzene; Drug Synergism; Epoxy Compounds; Ethacrynic Acid; Ethylmorphine-N-Demethylase; Glutathione; Glutathione Transferase; Liver; Male; Mice; Mixed Function Oxygenases; Nickel; Nitrobenzenes; Nitrophenols; Protease Inhibitors; Substrate Specificity

1995
Differential combined effect of cadmium and nickel on hepatic and renal glutathione S-transferases of the guinea pig.
    Environmental health perspectives, 1994, Volume: 102 Suppl 9

    Topics: Animals; Benzoates; Benzoic Acid; Cadmium; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Guinea Pigs; Kidney; Liver; Male; Nickel; Nitrobenzenes; Nitrophenols; Organophosphorus Compounds; Substrate Specificity

1994
Biotransformation in Egyptian spiny mouse Acomys cahirinus.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 110, Issue:1

    Topics: 2-Naphthylamine; Animals; Benzo(a)pyrene; Benzphetamine; Biotransformation; Coumarins; Cytochrome P-450 Enzyme System; Dinitrochlorobenzene; Epoxide Hydrolases; Epoxy Compounds; Ethacrynic Acid; Female; Fluorenes; Glucuronosyltransferase; Glutathione Transferase; Intestines; Kidney; Liver; Male; Methylation; Muridae; Naphthols; Oxazines; Oxygenases; Sex Factors

1995
A study of gender, strain and age differences in mouse liver glutathione-S-transferase.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 110, Issue:1

    Topics: Aging; Animals; Atrazine; Benzene Derivatives; Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Female; Glutathione Transferase; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitrobenzenes; Rats; Rats, Sprague-Dawley; Sex Characteristics; Species Specificity; Substrate Specificity

1995
Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells.
    Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1

    Topics: Biological Transport; Cells, Cultured; Cholic Acid; Cholic Acids; Dinitrochlorobenzene; Ethacrynic Acid; Hematopoietic Stem Cells; Humans; Indomethacin; Lymphocytes; Methotrexate; Prostaglandins A

1995
Enzymatic characteristics of chimeric mYc/rYc1 glutathione S-transferases.
    Cancer research, 1994, Sep-01, Volume: 54, Issue:17

    Topics: Aflatoxin B1; Amino Acid Sequence; Androstenedione; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Molecular Sequence Data; Recombinant Fusion Proteins; Structure-Activity Relationship

1994
Combined effects of cadmium and nickel on hepatic glutathione S-transferases in rats.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1993, Volume: 104, Issue:3

    Topics: Animals; Cadmium; Dinitrochlorobenzene; Drug Interactions; Ethacrynic Acid; Glutathione Transferase; Liver; Male; Nickel; Nitrobenzenes; Rats

1993
The effects of thiol modifiers on the activation of NF kappa B by interleukin-1.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Acetylcysteine; Animals; Cell Line; Cell Nucleus; Diamide; Dinitrochlorobenzene; Ethacrynic Acid; Humans; Hydrogen Peroxide; Interleukin-1; Mice; NF-kappa B; Sulfhydryl Reagents; T-Lymphocytes; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured

1993
Inter-individual variability of human hepatic glutathione S-transferase isozymes assessed by inhibitory capacity.
    Toxicology, 1994, Mar-11, Volume: 88, Issue:1-3

    Topics: Benzene Derivatives; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Humans; Individuality; Isoenzymes; Liver; Substrate Specificity

1994
Functional implications from the effects of 1-chloro-2,4-dinitrobenzene and ethacrynic acid on efflux routes for methotrexate and cholate in L1210 cells.
    The Journal of biological chemistry, 1994, May-06, Volume: 269, Issue:18

    Topics: Adenosine Triphosphate; Animals; Anions; Biological Transport; Cholic Acid; Cholic Acids; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Leukemia L1210; Methotrexate; Mice; Tumor Cells, Cultured

1994
Site-directed mutagenesis study on the roles of evolutionally conserved aspartic acid residues in human glutathione S-transferase P1-1.
    Protein engineering, 1993, Volume: 6, Issue:1

    Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Biological Evolution; Conserved Sequence; Dinitrochlorobenzene; Enzyme Stability; Ethacrynic Acid; Glutathione; Glutathione Transferase; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship

1993
Isoenzyme selective irreversible inhibition of rat and human glutathione S-transferases by ethacrynic acid and two brominated derivatives.
    Biochemical pharmacology, 1993, Feb-09, Volume: 45, Issue:3

    Topics: Animals; Binding Sites; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Rats

1993
Differences in hepatic drug metabolizing enzymes and their response to lindane in rat, rabbit and monkey.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Catalase; Cytochrome P-450 Enzyme System; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Ethacrynic Acid; Glutathione Transferase; Heme Oxygenase (Decyclizing); Hexachlorocyclohexane; Insecticides; Irritants; Lipid Peroxidation; Liver; Macaca mulatta; Molecular Weight; NADPH-Ferrihemoprotein Reductase; Rabbits; Rats; Rats, Wistar; Species Specificity

1995
Glutathione S-transferases in the Japanese quail: tissue distribution and purification of the liver isozymes.
    Journal of biochemical toxicology, 1996, Volume: 11, Issue:2

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Brain; Butanones; Coturnix; Cytosol; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Epoxy Compounds; Ethacrynic Acid; Etiocholanolone; Female; Glutathione Transferase; Isoelectric Focusing; Kidney; Liver; Lung; Male; Molecular Sequence Data; Nitrobenzenes; Nitrophenols; Protease Inhibitors; Sequence Alignment; Sequence Homology, Amino Acid; Stilbenes; Tissue Distribution

1996
Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
    Biochemistry, 1997, May-20, Volume: 36, Issue:20

    Topics: 4-Chloro-7-nitrobenzofurazan; Crystallography, X-Ray; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Substrate Specificity; Tyrosine; Viscosity

1997
Cytotoxicity of xenobiotics and expression of glutathione-S-transferases in immortalised rat hepatocyte cell lines.
    Human & experimental toxicology, 1998, Volume: 17, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Immunoblotting; Isoenzymes; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Toxicity Tests; Xenobiotics

1998
Identification of amino acid residues essential for high aflatoxin B1-8,9-epoxide conjugation activity in alpha class glutathione S-transferases through site-directed mutagenesis.
    Toxicology and applied pharmacology, 1998, Volume: 152, Issue:1

    Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Binding Sites; Dinitrochlorobenzene; Epitopes; Escherichia coli; Ethacrynic Acid; Glutathione Transferase; Mice; Microsomes, Liver; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid

1998
Circadian variation of hepatic glutathione S-transferase activities in the mouse.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:1

    Topics: Animals; Circadian Rhythm; Darkness; Dinitrochlorobenzene; Epoxy Compounds; Ethacrynic Acid; Female; Glutathione; Glutathione Transferase; Light; Liver; Male; Mice; Mice, Inbred Strains; Nitrobenzenes; Nitrophenols; Protease Inhibitors; Seasons; Sex Factors

1999
The role of tyrosine-9 and the C-terminal helix in the catalytic mechanism of Alpha-class glutathione S-transferases.
    The Biochemical journal, 1999, Nov-01, Volume: 343 Pt 3

    Topics: Amino Acid Substitution; Binding Sites; Catalysis; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Tyrosine

1999
Lipoxygenase-another pathway for glutathione conjugation of xenobiotics: A study with human term placental lipoxygenase and ethacrynic acid.
    Archives of biochemistry and biophysics, 1999, Nov-15, Volume: 371, Issue:2

    Topics: Chromatography, Affinity; Dinitrochlorobenzene; Ethacrynic Acid; Female; Glutathione; Humans; Linoleic Acid; Lipoxygenase; Placenta; Pregnancy; Xenobiotics

1999
Effects of beta-naphthoflavone on the levels of glutathione S-transferase from liver of Pacu, Piaractus mesopotamicus.
    Bulletin of environmental contamination and toxicology, 2000, Volume: 64, Issue:2

    Topics: Analysis of Variance; Animals; Benzene Derivatives; beta-Naphthoflavone; Brazil; Cytosol; Dinitrochlorobenzene; Enzyme Inhibitors; Ethacrynic Acid; Fishes; Glutathione Transferase; Liver; Nitrobenzenes; Substrate Specificity

2000
Isoenzymes of glutathione S-transferase from the mosquito Anopheles dirus species B: the purification, partial characterization and interaction with various insecticides.
    Insect biochemistry and molecular biology, 2000, Volume: 30, Issue:5

    Topics: Animals; Anopheles; Dinitrochlorobenzene; Drug Resistance; Ethacrynic Acid; Glutathione Transferase; Inactivation, Metabolic; Insecticides; Isoenzymes; Lyases; Substrate Specificity; Sulfobromophthalein

2000
Comparative metabolism and excretion of benzo(a)pyrene in 2 species of ictalurid catfish.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Animals; Benzo(a)pyrene; Bile; Carcinogens; Cytochrome P-450 CYP1A1; Cytosol; Dinitrochlorobenzene; DNA; DNA Adducts; Epoxide Hydrolases; Ethacrynic Acid; Glutathione Transferase; Ictaluridae; In Vitro Techniques; Liver; Microsomes, Liver; Species Specificity

2000
Valine 10 may act as a driver for product release from the active site of human glutathione transferase P1-1.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Alanine; Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Glycine; Humans; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Spectrophotometry; Substrate Specificity; Valine

2000
Differential induction of glutathione S-transferases in the clam Ruditapes decussatus exposed to organic compounds.
    Environmental toxicology and chemistry, 2001, Volume: 20, Issue:3

    Topics: Animals; Antibody Specificity; Benzo(a)pyrene; Bivalvia; Blotting, Western; Cytosol; Dichloroethylenes; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethacrynic Acid; Excitatory Amino Acid Antagonists; Glutathione Transferase; Immunoblotting; Organic Chemicals; Phenobarbital

2001
Rapid spectrophotometric method for serum glutathione S-transferases activity.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 326, Issue:1-2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Child; Child, Preschool; Dinitrochlorobenzene; Enzyme Inhibitors; Enzyme Stability; Ethacrynic Acid; Ethanol; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Isoenzymes; Liver Diseases; Male; Middle Aged; Reference Standards; Sensitivity and Specificity; Spectrophotometry; Triazines

2002
Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin.
    Chemical research in toxicology, 2003, Volume: 16, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Baculoviridae; Cell Line; Curcumin; Cyclosporine; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Ethacrynic Acid; Fluoresceins; Glutathione; Glutathione Transferase; Humans; Propionates; Quinolines; Recombinant Proteins; Spodoptera

2003
Characterization and molecular cloning of a glutathione S-transferase from the whitefly Bemisia tabaci (Hemiptera: Aleyrodidae).
    Insect biochemistry and molecular biology, 2004, Volume: 34, Issue:4

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cloning, Molecular; Dicumarol; Dinitrochlorobenzene; DNA, Complementary; Enzyme Inhibitors; Ethacrynic Acid; Glutathione Transferase; Hemiptera; Inhibitory Concentration 50; Kinetics; Molecular Sequence Data; Phylogeny; Pyrazoles; Recombinant Proteins; Sequence Analysis, Protein; Species Specificity; Substrate Specificity

2004
Molecular cloning, expression and characterization of glutathione S-transferase from Mytilus edulis.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2004, Volume: 139, Issue:2

    Topics: Animals; Base Sequence; Bivalvia; Cloning, Molecular; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Substrate Specificity; Temperature

2004
Biochemical characterization and distribution of glutathione S-transferases in leaping mullet (Liza saliens).
    Biochemistry. Biokhimiia, 2004, Volume: 69, Issue:9

    Topics: Animals; Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Mediterranean Sea; Smegmamorpha; Temperature; Turkey

2004
Filarial glutathione S-transferase: its induction by xenobiotics and potential as drug target.
    Acta biochimica Polonica, 2005, Volume: 52, Issue:2

    Topics: Animals; Butylated Hydroxyanisole; Dactinomycin; Diethylcarbamazine; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Ellagic Acid; Enzyme Activation; Ethacrynic Acid; Female; Glutathione Transferase; Phenobarbital; Setaria Nematode; Substrate Specificity

2005
Characterization of cytosolic glutathione S-transferases in juvenile Chinook salmon (Oncorhynchus tshawytscha).
    Aquatic toxicology (Amsterdam, Netherlands), 2005, Jul-01, Volume: 73, Issue:3

    Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Computational Biology; Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Immunoblotting; Mass Spectrometry; Molecular Sequence Data; Salmon; Sequence Alignment

2005
Salinity effects on activity and expression of glutathione S-transferases in white sturgeon and Chinook salmon.
    Ecotoxicology and environmental safety, 2006, Volume: 63, Issue:2

    Topics: Animals; Dinitrochlorobenzene; Ethacrynic Acid; Fishes; Glutathione; Glutathione Transferase; Liver; Salmon; Sodium Chloride

2006
Effects of metals and detergents on biotransformation and detoxification enzymes of leaping mullet (Liza saliens).
    Ecotoxicology and environmental safety, 2007, Volume: 68, Issue:3

    Topics: Animals; Biomarkers; Biotransformation; Cytochrome P-450 CYP1A1; Detergents; Dinitrochlorobenzene; Environmental Monitoring; Enzyme Inhibitors; Ethacrynic Acid; Fish Proteins; Glutathione Transferase; Inactivation, Metabolic; Liver; Metals; Microsomes, Liver; Oxazines; Smegmamorpha; Substrate Specificity; Water Pollutants, Chemical

2007
Characterization of hepatic glutathione S-transferases in coho salmon (Oncorhynchus kisutch).
    Aquatic toxicology (Amsterdam, Netherlands), 2007, Feb-28, Volume: 81, Issue:2

    Topics: Amino Acid Sequence; Animals; Atrazine; Bilirubin; Cytosol; Dinitrochlorobenzene; Enzyme Inhibitors; Ethacrynic Acid; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Herbicides; Insecticides; Liver; Methyl Parathion; Oncorhynchus kisutch; Sequence Alignment; Sequence Analysis, Protein; Water Pollutants, Chemical

2007
Inhibition of thioredoxin reductase induces apoptosis in neuronal cell lines: role of glutathione and the MKK4/JNK pathway.
    Biochemical and biophysical research communications, 2007, Aug-03, Volume: 359, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Dinitrochlorobenzene; Enzyme Inhibitors; Ethacrynic Acid; Glutathione; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Microscopy, Electron; Neurons; PC12 Cells; Rats; Reactive Oxygen Species; Thioredoxin-Disulfide Reductase

2007
Molecular cloning and thermal stress-induced expression of a pi-class glutathione S-transferase (GST) in the Antarctic bivalve Laternula elliptica.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2009, Volume: 152, Issue:2

    Topics: Adaptation, Physiological; Amino Acid Sequence; Animals; Antarctic Regions; Base Sequence; Bivalvia; Cloning, Molecular; Cold Temperature; Digestive System; Dinitrochlorobenzene; Enzyme Induction; Ethacrynic Acid; Gills; Glutathione S-Transferase pi; Hot Temperature; Hydrogen-Ion Concentration; Isoelectric Point; Molecular Sequence Data; Molecular Weight; Phylogeny; Recombinant Proteins; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Sequence Analysis, Protein; Stress, Physiological; Substrate Specificity

2009
Hepatic and branchial glutathione S-transferases of two fish species: substrate specificity and biotransformation of microcystin-LR.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 149, Issue:4

    Topics: Animals; Biotransformation; Carps; Chromatography, Affinity; Chromatography, Ion Exchange; Cyprinidae; Dinitrochlorobenzene; Ethacrynic Acid; Gills; Glutathione Transferase; Isoenzymes; Liver; Marine Toxins; Microcystins; Nitrobenzenes; Substrate Specificity

2009
The characterization of cytosolic glutathione transferase from four species of sea turtles: loggerhead (Caretta caretta), green (Chelonia mydas), olive ridley (Lepidochelys olivacea), and hawksbill (Eretmochelys imbricata).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 150, Issue:2

    Topics: Animals; Biotransformation; Cytosol; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione; Glutathione Transferase; Kinetics; Liver; Nitrobenzenes; Species Specificity; Substrate Specificity; Turtles

2009
Biochemical analysis of a recombinant glutathione transferase from the cestode Echinococcus granulosus.
    Acta tropica, 2010, Volume: 114, Issue:1

    Topics: Aldehydes; Animals; Benzene Derivatives; Dimerization; Dinitrochlorobenzene; Echinococcus granulosus; Enzyme Inhibitors; Ethacrynic Acid; Glutathione Peroxidase; Glutathione Transferase; Recombinant Proteins; Substrate Specificity

2010
Alpha-class glutathione S-transferases in wild turkeys (Meleagris gallopavo): characterization and role in resistance to the carcinogenic mycotoxin aflatoxin B1.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Aflatoxin B1; Animals; Benzene Derivatives; Carcinogens; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Isoenzymes; Nitrobenzenes; Phylogeny; Polymorphism, Single Nucleotide; Turkeys

2013
Heterologous expression and functional characterization of avian mu-class glutathione S-transferases.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2013, Volume: 158, Issue:2

    Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Benzene Derivatives; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Inactivation, Metabolic; Liver; Male; Molecular Sequence Data; Nitrobenzenes; Sequence Alignment; Substrate Specificity; Turkeys

2013
In Vitro Inhibition of Human Placental Glutathione S-Transferase by 3-Arylcoumarin Derivatives.
    Archiv der Pharmazie, 2015, Volume: 348, Issue:9

    Topics: Antineoplastic Agents; Coumarins; Dinitrochlorobenzene; Drug Design; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethacrynic Acid; Female; Glutathione S-Transferase pi; Humans; Molecular Structure; Placenta; Pregnancy; Structure-Activity Relationship

2015