ethacrynic acid and cysteine
ethacrynic acid has been researched along with cysteine in 45 studies
Research
Studies (45)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 22 (48.89) | 18.7374 |
1990's | 12 (26.67) | 18.2507 |
2000's | 5 (11.11) | 29.6817 |
2010's | 6 (13.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
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Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Magro, AM | 1 |
Jaques, R | 1 |
Tokita, S | 1 |
Ahlers, J; Günther, T | 1 |
Schnermann, J | 1 |
Barnes, LD; Dousa, TP; Hui, YS | 1 |
Cafruny, EJ; Koechel, DA | 1 |
Brown, RD | 2 |
Burg, MB | 1 |
Epstein, DL; Epstein, MP; Hooshmand, LB | 1 |
Inoue, H; Kong, KH; Takahashi, K | 1 |
Carraway, RE; Doh, PS; Han, DS; Lee, CJ; Miller, TB; Park, CS | 1 |
Dobrowolski, L; Kompanowska-Jezierska, E; Sadowski, J | 1 |
Brodie, AE; Reed, DJ | 1 |
Gescher, A; Harpur, ES; Lazenby, CM; Lee, SJ | 1 |
Jakschik, B; Johnson, EM; Needleman, P | 1 |
Davis, PW | 1 |
Gisvold, O; Koechel, DA | 1 |
Chang, M; Ferrendelli, JA; Johnson, EM; Needleman, P | 1 |
Burg, M; Green, N | 1 |
Epstein, RW | 2 |
Geck, P; Heinz, E; Pfeiffer, B | 1 |
Brunet, C; Cazin, M; Delacourte, A; Lesieur, D; Luyckx, M; Mallevais, ML | 1 |
Weiner, MW | 1 |
Bank, N; Lief, PD; Mutz, BF | 1 |
Brosch, SF; Li, CG; Rand, MJ | 1 |
Andrisano, V; Bonazzi, D; Cavrini, V; Di Pietra, AM; Gotti, R | 1 |
Epstein, DL; Ludueña, RF; Roach, MC | 1 |
Kachar, B; Kalinec, F | 1 |
Mutschler, E; Spahn-Langguth, H; Voith, B | 1 |
Franklin, E; Mantle, TJ; Walsh, SB | 1 |
Bertucci, C; Nanni, B; Raffaelli, A; Salvadori, P | 1 |
Büyüknacar, HS; Dikmen, A; Göçmen, C; Onder, S; Resim, S | 1 |
Ergün, Y; Ogülener, N | 1 |
Bowes, TJ; Gupta, RS | 1 |
Delude, RL; Englert, JA; Fink, MP; Han, Y | 1 |
Arnold, JJ; Challa, P; Chen, X; Choksi, Y; Epstein, DL; Hatten, J; Shimazaki, A; Toone, EJ | 1 |
Carbone, V; Gambarini, G; Giardina, B; Lupi, A; Martorana, GE; Nocca, G; Ragno, R; Rossetti, DV | 1 |
Casini, A; De Luca, A; Dyson, PJ; Hartinger, CG; Lo Bello, M | 1 |
Aydinoglu, F; Kıroğlu, OE; Oğülener, N | 1 |
Abegg, D; Adibekian, A; Barluenga, S; Daguer, JP; Müller, S; Tallant, C; Winssinger, N; Zambaldo, C | 1 |
Chen, X; Lei, X; Song, T; Wang, C; Ye, Z; Zhang, X; Zhu, Y | 1 |
Reviews
2 review(s) available for ethacrynic acid and cysteine
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Regulation of single nephron filtration rate by feedback-facts and theories.
Topics: Animals; Blood Pressure; Choline; Cysteine; Dogs; Ethacrynic Acid; Feedback; Furosemide; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Microinjections; Models, Biological; Nephrons; Perfusion; Pressure; Rats | 1975 |
Other Studies
43 other study(ies) available for ethacrynic acid and cysteine
Article | Year |
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Blocking of histamine release from human basophils in vitro by the ATPase inhibitor, ethacrynic acid.
Topics: Adenosine Triphosphatases; Basophils; Calcimycin; Cysteine; Dose-Response Relationship, Immunologic; Ethacrynic Acid; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Ouabain; Sulfhydryl Compounds | 1977 |
Antagonism of non-steroidal anti-inflammatory drugs and narcotic analgesics against ethacrynic acid induced writhing.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Cysteine; Ethacrynic Acid; Male; Mice; Narcotic Antagonists; Spasm | 1977 |
[Effect of ethacrynic acid on contractility and Ca flux of guinea pig taenia coli smooth muscle (author's transl)].
Topics: Acetylcholine; Animals; Calcium; Cysteine; Ethacrynic Acid; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium | 1977 |
Specificity of ethacrynic acid as a sulfhydryl reagent.
Topics: Cysteine; Ethacrynic Acid; Histidine; Imidazoles; L-Lactate Dehydrogenase; Lysine; Serine; Sulfhydryl Reagents | 1976 |
Interaction of ethacrynic acid and cysteine with renal medullary adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cysteine; Dogs; Ethacrynic Acid; Fluorides; Kidney; Kidney Medulla; Kinetics; Protein Binding | 1975 |
Thiol adducts of ethacrynic acid: a correlation of the rate of liberation of ethacrynic acid with the onset and magnitude of the diuretic response.
Topics: Analysis of Variance; Animals; Biotransformation; Chlorides; Cysteine; Diuresis; Dogs; Dose-Response Relationship, Drug; Drug Stability; Ethacrynic Acid; Female; Male; Potassium; Sodium; Sulfhydryl Compounds; Sulfides; Time Factors | 1975 |
Comparison of the cochlear toxicity of sodium ethacrynate, furosemide, and the cysteine adduct of sodium ethacrynate in cats.
Topics: Animals; Cats; Cochlea; Cysteine; Depression, Chemical; Ethacrynic Acid; Female; Furosemide; Hearing; Male; Time Factors | 1975 |
Renal chloride transport and diuretics.
Topics: Biological Transport, Active; Chlorides; Cysteine; Depression, Chemical; Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Natriuresis; Organomercury Compounds | 1976 |
Thiol adducts of ethacrynic acid increase outflow facility in enucleated calf eyes.
Topics: Animals; Anterior Chamber; Aqueous Humor; Cattle; Cysteamine; Cysteine; Ethacrynic Acid; Eye Enucleation; Glutathione; Perfusion | 1992 |
Non-essentiality of cysteine and histidine residues for the activity of human class PI glutathione S-transferase.
Topics: Base Sequence; Cysteine; Dinitrochlorobenzene; DNA; Escherichia coli; Ethacrynic Acid; Glutathione Transferase; Histidine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Structure-Activity Relationship; Transfection | 1991 |
Cellular mechanism of stimulation of renin secretion by the mercurial diuretic mersalyl.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Chlorides; Cysteine; Ethacrynic Acid; In Vitro Techniques; Kidney Cortex; Mersalyl; Potassium; Rabbits; Renin; Sodium; Stimulation, Chemical | 1991 |
Cysteine enhances in vivo natriuretic potency of ethacrynic acid in the rat.
Topics: Animals; Cysteine; Ethacrynic Acid; Kidney; Kidney Medulla; Loop of Henle; Male; Natriuresis; Rats; Rats, Inbred Strains | 1990 |
Cellular recovery of glyceraldehyde-3-phosphate dehydrogenase activity and thiol status after exposure to hydroperoxides.
Topics: Cell Line; Cysteamine; Cysteine; Cystine; Dithiothreitol; Ethacrynic Acid; Ethylmaleimide; Glutathione; Glutathione Disulfide; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Kinetics; Lung Neoplasms; Oxidation-Reduction; Peroxides; Sulfhydryl Compounds; tert-Butylhydroperoxide; Ultrasonics | 1990 |
Glutathione depletion in the guinea pig and its effect on the acute cochlear toxicity of ethacrynic acid.
Topics: Animals; Buthionine Sulfoximine; Cochlea; Cysteine; Ethacrynic Acid; Female; Glutathione; Guinea Pigs; Kidney; Liver; Male; Methionine Sulfoximine; Species Specificity | 1988 |
Sulfhydryl requirement for relaxation of vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Cysteine; Dose-Response Relationship, Drug; Ethacrynic Acid; Furosemide; Hydrogen-Ion Concentration; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nitrites; Nitroglycerin; Norepinephrine; Rabbits; Refractory Period, Electrophysiological; Sulfhydryl Compounds; Vasodilator Agents | 1973 |
Inhibition of renal Na + ,K + -activated adenosine triphosphatase activity by ethacrynic acid.
Topics: Adenosine Triphosphatases; Animals; Benzoates; Benzocycloheptenes; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Enzyme Activation; Ethacrynic Acid; Guinea Pigs; Indenes; Kidney; Magnesium; Male; Mercury; Microsomes; Organometallic Compounds; Ouabain; Potassium Chloride; Sodium Chloride; Sulfhydryl Reagents; Sulfides | 1970 |
Synthesis and pharmacology of an epoxide derivative of ethacrynic acid.
Topics: Adenosine Triphosphatases; Animals; Cysteine; Diuresis; Ethacrynic Acid; Ethers, Cyclic; Glomerular Filtration Rate; Kidney; Kinetics; Potassium; Protein Binding; Sodium; Structure-Activity Relationship; Sulfhydryl Compounds | 1971 |
Cochlear N1 depression produced by the sodium salts of ethacrynic acid and its cysteine adduct.
Topics: Animals; Auditory Threshold; Cats; Cochlea; Cysteine; Depression, Chemical; Dose-Response Relationship, Drug; Ethacrynic Acid; Female; Isotonic Solutions; Male; Sodium; Time Factors | 1973 |
Inhibition of brain adenylate cyclase by ethacrynic acid and dithiobisnitrobenzoic acid.
Topics: Adenylyl Cyclase Inhibitors; Animals; Benzoates; Brain; Cerebral Cortex; Cysteine; Disulfides; Dithiothreitol; Ethacrynic Acid; Female; Mice; Nitro Compounds | 1973 |
Effect of ethacrynic acid on the thick ascending limb of Henle's loop.
Topics: Absorption; Animals; Biological Transport, Active; Buffers; Chlorides; Cysteine; Electric Conductivity; Epithelium; Ethacrynic Acid; In Vitro Techniques; Kidney Tubules; Loop of Henle; Membrane Potentials; Potassium; Rabbits; Sodium; Time Factors | 1973 |
The binding of ethacrynic acid to rabbit kidney cortex.
Topics: Animals; Binding Sites; Biological Transport; Carbon Isotopes; Cysteine; Dinitrophenols; Ethacrynic Acid; Hexoses; In Vitro Techniques; Kidney; Kinetics; Ouabain; Rabbits; Sodium; Sulfhydryl Reagents; Temperature | 1972 |
The effects of ethacrynic acid on active transport of sugars and ions and on other metabolic processes in rabbit kidney cortex.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Chlorides; Cysteine; Ethacrynic Acid; Glycolates; Glycosides; Hexoses; In Vitro Techniques; Ketones; Kidney; Kinetics; Ouabain; Oxygen Consumption; Potassium; Rabbits; Sodium; Structure-Activity Relationship; Water-Electrolyte Balance | 1972 |
Influence of high ceiling diuretics on ion fluxes and cell volume of ehrlich ascites tumour cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Chlorides; Cysteine; Diuretics; Ethacrynic Acid; Furosemide; Ion Channels; Ion Exchange; Osmotic Fragility; Ouabain; Potassium; Potassium Radioisotopes; Sodium; Theophylline | 1981 |
Antimicrotubular effects of ethacrynic acid.
Topics: Animals; Binding, Competitive; Brain; Cattle; Colchicine; Cysteine; Ethacrynic Acid; In Vitro Techniques; Mercaptoethanol; Microtubules | 1984 |
Effects of furosemide and ethacrynic acid on sodium transport and CO2 production of toad bladders: evidence for direct inhibition of active transport.
Topics: Animals; Biological Transport, Active; Bufo marinus; Carbon Dioxide; Cysteine; Dinitrophenols; Energy Metabolism; Ethacrynic Acid; Furosemide; In Vitro Techniques; Mucous Membrane; Osmolar Concentration; Sodium; Urinary Bladder | 1980 |
Diuretics stimulate H+ secretion in turtle urinary bladder.
Topics: Animals; Borates; Chlorothiazide; Cysteine; Diuretics; Electric Conductivity; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Mucous Membrane; Sodium; Sulfisoxazole; Time Factors; Turtles; Urinary Bladder | 1980 |
Inhibition by ethacrynic acid of NO-mediated relaxations of the rat anococcygeus muscle.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cysteine; Drug Interactions; Electric Stimulation; Ethacrynic Acid; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Papaverine; Rats; Rats, Sprague-Dawley | 1994 |
HPLC determination of glutathione and L-cysteine in pharmaceuticals after derivatization with ethacrynic acid.
Topics: Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cysteine; Dithiothreitol; Ethacrynic Acid; Glutathione; Oxidation-Reduction; Powders; Stereoisomerism; Tablets | 1994 |
Interaction of ethacrynic acid with bovine brain tubulin.
Topics: Alkylation; Animals; Brain; Cattle; Cysteine; Ethacrynic Acid; Iodoacetamide; Microtubules; Tubulin | 1994 |
Inhibition of outer hair cell electromotility by sulfhydryl specific reagents.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Cell Movement; Cysteine; Cystine; Diamide; Electric Stimulation; Ethacrynic Acid; Ethylmaleimide; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Proteins; Mersalyl; Nerve Tissue Proteins; Protein Conformation; Sulfhydryl Reagents | 1993 |
New specific and sensitive HPLC-assays for ethacrynic acid and its main metabolite--the cysteine conjugate--in biological material.
Topics: Chromatography, High Pressure Liquid; Cysteine; Diuretics; Drug Stability; Ethacrynic Acid; Humans; Sensitivity and Specificity | 1995 |
Evidence for modulation of the interaction between Cys-47 and Lys-54 in glutathione S-transferase Pi by the nature of the residue at position 56.
Topics: Animals; Binding Sites; Cysteine; Ethacrynic Acid; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Lysine; Mice | 1997 |
Chemical modification of human albumin at cys34 by ethacrynic acid: structural characterisation and binding properties.
Topics: Albumins; Bilirubin; Binding Sites; Circular Dichroism; Cysteine; Diazepam; Electrophoresis; Ethacrynic Acid; Humans; Mass Spectrometry; Molecular Structure; Phenylbutazone; Protein Binding | 1998 |
A possible effect of sulfhydryl reagents on the contractile activity of the rat detrusor muscle.
Topics: Acetylcholine; Animals; Cysteine; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Ethacrynic Acid; Ethylmaleimide; Glutathione; In Vitro Techniques; Muscle Contraction; Rats; Rats, Inbred WKY; Sulfhydryl Reagents; Urinary Bladder; Vasodilator Agents; Verapamil | 2002 |
A putative role for S-nitrosoglutathione as the source of nitric oxide in photorelaxation of the mouse gastric fundus.
Topics: Acetylcysteine; Animals; Cysteine; Diamide; Enzyme Inhibitors; Ethacrynic Acid; Female; Gastric Fundus; Glutathione; In Vitro Techniques; Isoproterenol; Male; Mice; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; S-Nitrosoglutathione; S-Nitrosothiols; Ultraviolet Rays | 2002 |
Induction of mitochondrial fusion by cysteine-alkylators ethacrynic acid and N-ethylmaleimide.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line; Cell Survival; Cricetinae; Cysteine; Ethacrynic Acid; Ethylmaleimide; Glutathione; Membrane Fusion; Mitochondria; Molecular Structure; Sulfhydryl Reagents; Vitamin E | 2005 |
Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cell-Free System; Cysteine; Cytosol; Dimerization; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethacrynic Acid; Genes, Reporter; Glutathione; Humans; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Mice; Models, Chemical; Models, Molecular; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Transcription Factor RelA; Transcription Factors | 2005 |
Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits.
Topics: Administration, Topical; Animals; Biological Availability; Chromatography, High Pressure Liquid; Cinnamates; Conjunctiva; Conjunctival Diseases; Cornea; Cysteine; Dose-Response Relationship, Drug; Drug Combinations; Ethacrynic Acid; Hyperemia; In Vitro Techniques; Intraocular Pressure; Male; Ophthalmic Solutions; Permeability; Prodrugs; Rabbits | 2009 |
Identification of glutathione-methacrylates adducts in gingival fibroblasts and erythrocytes by HPLC-MS and capillary electrophoresis.
Topics: Biocatalysis; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Cysteine; Cytoplasm; Erythrocytes; Ethacrynic Acid; Extracellular Space; Fibroblasts; Gingiva; Glutathione; Glutathione Transferase; Humans; Materials Testing; Methacrylates; Molecular Conformation; Polyethylene Glycols; Polymethacrylic Acids; Tandem Mass Spectrometry | 2011 |
A new target for gold(I) compounds: glutathione-S-transferase inhibition by auranofin.
Topics: Antineoplastic Agents; Antirheumatic Agents; Auranofin; Binding Sites; Cysteine; Enzyme Inhibitors; Ethacrynic Acid; Glutathione S-Transferase pi; Humans; Kinetics; Mutation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared | 2013 |
The effects of thiol modulators on nitrergic nerve- and S-nitrosothiols-induced relaxation in duodenum.
Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cysteine; Diuretics; Dose-Response Relationship, Drug; Duodenum; Ethacrynic Acid; Female; Glutamate-Cysteine Ligase; Glutathione Transferase; Male; Mice; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Sulfhydryl Reagents; Sulfobromophthalein; Synaptic Transmission; Vasodilator Agents | 2013 |
Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules.
Topics: Binding Sites; Cysteine; DNA; Epigenesis, Genetic; Ethacrynic Acid; Humans; Models, Molecular; Molecular Probes; Molecular Structure; Protein Structure, Tertiary; Proteomics; Small Molecule Libraries | 2015 |
Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function.
Topics: Cell Line, Tumor; Cysteine; Drug Repositioning; Drug Screening Assays, Antitumor; Ethacrynic Acid; Humans; Mitochondria; Mitochondrial ADP, ATP Translocases; Neoplasms; Proteome; Proteomics; Reactive Oxygen Species | 2018 |