Compounds > ethacrynic acid

ethacrynic acid and cyclosporine

ethacrynic acid has been researched along with cyclosporine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Hoffman, DW; Rybak, LP; Wiebkin, P1
Osmak, M; Vuković, L1
Boersma, MG; Cnubben, NH; Rietjens, IM; Spenkelink, B; Usta, M; van Bladeren, PJ; van der Velde, AE; van Zanden, JJ; Wortelboer, HM1
Muyderman, H; Nilsson, M; Sims, NR1

Reviews

1 review(s) available for ethacrynic acid and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for ethacrynic acid and cyclosporine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Inhibition of glutathione-related enzymes and cytotoxicity of ethacrynic acid and cyclosporine.
    Biochemical pharmacology, 1995, Jan-31, Volume: 49, Issue:3

    Topics: Animals; Chemotherapy, Adjuvant; Cyclosporine; Drug Interactions; Ethacrynic Acid; Glutathione; Glutathione Reductase; Glutathione Transferase; Inactivation, Metabolic; Kidney; Rats

1995
Reversal of carboplatin resistance in human laryngeal carcinoma cells.
    Neoplasma, 1999, Volume: 46, Issue:6

    Topics: Amphotericin B; Antineoplastic Agents; Aphidicolin; Buthionine Sulfoximine; Carboplatin; Cyclosporine; Drug Resistance, Neoplasm; Drug Synergism; Ethacrynic Acid; Humans; Laryngeal Neoplasms; Tumor Cells, Cultured

1999
Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin.
    Chemical research in toxicology, 2003, Volume: 16, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Baculoviridae; Cell Line; Curcumin; Cyclosporine; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Ethacrynic Acid; Fluoresceins; Glutathione; Glutathione Transferase; Humans; Propionates; Quinolines; Recombinant Proteins; Spodoptera

2003
Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Cell Death; Cells, Cultured; Citrate (si)-Synthase; Cyclosporine; Cytoplasm; Electron Transport; Electron Transport Complex I; Ethacrynic Acid; Glutathione; Intracellular Membranes; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Molsidomine; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley

2004