Compounds > ethacrynic acid

ethacrynic acid and colchicine

ethacrynic acid has been researched along with colchicine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Breslow, JL; Davidson, RL; Epstein, J1
Gray, GM1
Brunet, C; Cazin, M; Delacourte, A; Lesieur, D; Luyckx, M; Mallevais, ML1
Epstein, DL; Harding, TW; Kinch, M; O'Brien, ET1
Epstein, DL; Gills, JP; Roberts, BC1

Reviews

2 review(s) available for ethacrynic acid and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drugs, malnutrition, and carbohydrate absorption.
    The American journal of clinical nutrition, 1973, Volume: 26, Issue:1

    Topics: Aged; Animals; Atropine; Carbohydrate Metabolism; Clinical Enzyme Tests; Colchicine; Cortisone; Dietary Carbohydrates; Digitoxin; Drug-Related Side Effects and Adverse Reactions; Ethacrynic Acid; Glycoside Hydrolases; Humans; Infant; Infant, Newborn; Intestinal Absorption; Intestinal Mucosa; Malabsorption Syndromes; Neomycin; Nutrition Disorders; Phenformin; Protein Deficiency; Sympathomimetics; Xylose

1973

Other Studies

9 other study(ies) available for ethacrynic acid and colchicine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increased dexamethasone resistance of cystic fibrosis fibroblasts.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:12

    Topics: Aminopterin; Biological Transport; Cell Survival; Cells, Cultured; Colchicine; Cystic Fibrosis; Dexamethasone; Ethacrynic Acid; Humans; Ouabain; Strophanthidin; Structure-Activity Relationship

1977
Antimicrotubular effects of ethacrynic acid.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:11

    Topics: Animals; Binding, Competitive; Brain; Cattle; Colchicine; Cysteine; Ethacrynic Acid; In Vitro Techniques; Mercaptoethanol; Microtubules

1984
A mechanism for trabecular meshwork cell retraction: ethacrynic acid initiates the dephosphorylation of focal adhesion proteins.
    Experimental eye research, 1997, Volume: 65, Issue:4

    Topics: Actins; Animals; Cattle; Cell Adhesion; Cell Adhesion Molecules; Cell Size; Cells, Cultured; Colchicine; Cytoskeletal Proteins; Endothelium, Vascular; Ethacrynic Acid; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Pulmonary Artery; Trabecular Meshwork

1997
Microtubule disruption leads to cellular contraction in human trabecular meshwork cells.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Cell Movement; Cell Size; Colchicine; Ethacrynic Acid; Humans; Microtubules; Trabecular Meshwork; Vinblastine

1998