ethacrynic acid has been researched along with chlorambucil in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Begleiter, A; Israels, LG; Johnston, JB; Mowat, MR; Yang, WZ | 1 |
| Ciaccio, PJ; LaCreta, FP; Tew, KD | 1 |
| Bomber, AM; Hoffman, SJ; Tew, KD | 1 |
| Caracciolo, F; Conte, A; Grassi, B; Petrini, M; Ronca, G; Sabbatini, A | 1 |
| Bello, ML; Ciccone, S; Hancock, NC; Italiano, LC; Morton, CJ; Oakley, AJ; Parker, LJ; Parker, MW; Primavera, A | 1 |
| Andersson, BS; Hassan, M; Valdez, BC | 1 |
1 review(s) available for ethacrynic acid and chlorambucil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
10 other study(ies) available for ethacrynic acid and chlorambucil
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Role of glutathione and glutathione S-transferase in chlorambucil resistance.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Buthionine Sulfoximine; Cell Survival; Chlorambucil; DNA; Drug Interactions; Drug Resistance; Ethacrynic Acid; Gene Rearrangement; Glutathione; Glutathione Transferase; Isoenzymes; Methionine Sulfoximine; Mice; RNA, Messenger | 1992 |
Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid.
Topics: Animals; Chlorambucil; Chromatography, High Pressure Liquid; Ethacrynic Acid; Female; Glutathione; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoelectric Focusing; Kinetics; Liver; Mice; Ovary | 1991 |
Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines.
Topics: Animals; Carcinoma 256, Walker; Cell Survival; Chlorambucil; Drug Resistance; Drug Synergism; Epoprostenol; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; In Vitro Techniques; Rats; Tumor Cells, Cultured | 1988 |
Reversing of chlorambucil resistance by ethacrynic acid in a B-CLL patient.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Resistance; Ethacrynic Acid; Glutathione Transferase; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphocytes; Male | 1993 |
The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants.
Topics: Alleles; Antineoplastic Agents; Chlorambucil; Crystallography, X-Ray; Enzyme Stability; Ethacrynic Acid; Glutathione; Glutathione S-Transferase pi; Humans; Kinetics; Mutant Proteins; Polymorphism, Genetic; Protein Structure, Secondary; Substrate Specificity; Temperature | 2008 |
Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions.
Topics: Antineoplastic Agents, Alkylating; Biological Transport; Busulfan; Cell Line, Tumor; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Interactions; Ethacrynic Acid; Everolimus; Flow Cytometry; Fluoresceins; Humans; Ketoconazole; Melphalan; Multidrug Resistance-Associated Proteins; Reproducibility of Results; Sirolimus | 2017 |