Page last updated: 2024-09-02

ethacizine and verapamil

ethacizine has been researched along with verapamil in 6 studies

Compound Research Comparison

Studies
(ethacizine)
Trials
(ethacizine)
Recent Studies (post-2010)
(ethacizine)
Studies
(verapamil)
Trials
(verapamil)
Recent Studies (post-2010) (verapamil)
8720217,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomyethacizine (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Baldenkov, GN; Ratner, EI; Tkachuk, VA1
Denisiuk, VI; Kotsuta, GI; Lipnitskiĭ, TN; Stepaniuk, AV1
Shpektor, AV; Susliak, NN1
Antonchenko, IV; Borisova, EV; Chekhov, AM; Gimrikh, EO; Plekhanov, IG; Popov, SV; Savenkova, GM1
Bankuzov, VA; Golitsyn, SP; Islam, MN; Malakhov, VI; Smetnev, AS; Sokolov, SF1
Kondratenko, SN; Kovachevich, IV; Kukes, VG; Polyakov, AV; Repenkova, LG; Savelyeva, MI; Svistunov, AA1

Trials

2 trial(s) available for ethacizine and verapamil

ArticleYear
[Evaluation of the possibility of selection of individual anti-arrhythmia therapy].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Humans; Middle Aged; Phenothiazines; Propranolol; Tachycardia, Atrioventricular Nodal Reentry; Verapamil

1991
[Comparative study of the effects of verapamil, ethmozin and ethacizine on provoked attacks of atrioventricular nodal reciprocal tachycardia].
    Kardiologiia, 1990, Volume: 30, Issue:2

    Topics: Adult; Atrioventricular Node; Cardiac Pacing, Artificial; Clinical Trials as Topic; Female; Heart Conduction System; Humans; Male; Middle Aged; Moricizine; Phenothiazines; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Supraventricular; Verapamil

1990

Other Studies

4 other study(ies) available for ethacizine and verapamil

ArticleYear
Effect of moracizine and ethacizine on receptors of potential-operated calcium channels and calcium-binding proteins.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Anti-Arrhythmia Agents; Calcium Channels; Calcium-Binding Proteins; Chlorpromazine; Electrophysiology; In Vitro Techniques; Ligands; Membrane Potentials; Moricizine; Phenothiazines; Phosphoric Diester Hydrolases; Protein Binding; Rabbits; Receptors, Nicotinic; Verapamil

1992
[Clinical efficacy of combined therapy with verapamil and fast sodium channel blockers for refractory atrial fibrillation].
    Kardiologiia, 1991, Volume: 31, Issue:11

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therapy, Combination; Humans; Middle Aged; Moricizine; Phenothiazines; Procainamide; Quinidine; Sodium Channels; Verapamil

1991
[Treatment of ventricular arrhythmia resistant to sodium channel blockaders].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Resistance; Humans; Middle Aged; Phenothiazines; Sodium Channels; Tachycardia, Paroxysmal; Verapamil

1991
Peculiarities of Pharmacokinetics and Bioavailability of Some Cardiovascular Drugs under Conditions of Antiorthostatic Hypokinesia.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:4

    Topics: Adult; Area Under Curve; Biological Availability; Cardiovascular Agents; Half-Life; Humans; Hypokinesia; Male; Middle Aged; Phenothiazines; Propranolol; Verapamil; Weightlessness Simulation

2020