etanidazole and misonidazole

etanidazole has been researched along with misonidazole in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	48 (69.57)	18.7374
1990's	17 (24.64)	18.2507
2000's	2 (2.90)	29.6817
2010's	2 (2.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anderson, RF; Bonnet, M; Gu, Y; Hay, MP; Hicks, KO; Hong, CR; Jamieson, SMF; Liew, LP; Pruijn, FB; Qi, W; Shome, A; Stevenson, RJ; Wang, J; Wilson, WR; Wong, WW	1
Stratford, MR	1
Moore, SK; Wallen, CA; Wheeler, KT	1
Chapman, JD; McPhee, MS; Santus, R; Stobbe, CC	1
Wallen, CA; Wheeler, KT; Wong, KH	2
Herman, TS; Holden, SA; Jones, SM; Pfeffer, MR; Teicher, BA	1
Abe, M; Hori, H; Inayama, S; Nagasawa, H; Sasai, K; Shibamoto, Y; Shibata, T; Takahashi, M; Zhou, L	1
Chapnick, RM; Herman, TS; Kalick, GS; Khandekar, V; Pfeffer, MR; Rabow, A; Teicher, BA	1
Mori, T; Murayama, C	2
DeGraff, WG; Gamson, J; Mitchell, JB; Russo, A	1
Calderwood, SK; Coleman, CN; Stevenson, MA	1
Hall, EJ; Hei, TK	1
Hickson, ID; Robson, CN; Stephens, M; Stratford, IJ	1
Mori, T	1
Herman, TS; Holden, SA; Jones, SM; Teicher, BA	1
Miyata, Y; Mori, T; Murayama, C; Sakaguchi, M; Suzuki, A; Suzuki, T; Tanabe, Y; Tanaka, N	1
Abe, M; Kagiya, T; Nishimoto, S; Sasai, K; Shibamoto, Y; Takahashi, M; Wang, J; Zhou, L	1
Allalunis-Turner, J; Applebaum, FR; Chapman, JD; Deeg, HJ; Graham, T; Shields, AF; Storb, R	1
Chapman, JD; Kanclerz, A	1
Adams, GE; Stratford, IJ	1
Astor, MB; Biaglow, JE; Clark, EP; Epp, ER; Hall, EJ; Roizen-Towle, L; Varnes, ME	1
Hill, RP	1
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Orchard, RA; Saunders, MI; Stratford, MR	1
Minchinton, AI; Stratford, MR	1
Biaglow, JE; Clark, EP; Donahue, LL; Epp, ER; Tuttle, SW; Varnes, ME	1
Ling, CC; Schell, MC; Spiro, IJ; Stickler, R	1
Abe, M; Fushiki, M; Nishidai, T; Ono, K; Sasai, K; Shibamoto, Y; Takahashi, M; Tsutsui, K	1
Bleehen, NM; Walton, MI; Workman, P	1
Brown, JM	3
Blaschke, T; Coleman, CN; Cox, RS; Halsey, J; Hancock, S; Hirst, VK; Howes, AE; Pajak, T; Urtasun, RC; Wasserman, TH	1
Roizin-Towle, L	1
Coleman, CN	1
Dische, S	1
Harris, JW; Shrieve, DC	1
Sinesi, MS; Stone, HB	1
Geard, CR; Rutledge-Freeman, MH; Spunberg, JJ	1
Abe, M; Hamanaka, D; Hiraoka, M; Nishidai, T; Ono, K; Takahashi, M	1
Brown, JM; Hazlehurst, JL; Hirst, DG	1
Brown, DM; Brown, JM; Dionet, C	1
Abe, M; Nishidai, T; Ono, K; Shibamoto, Y; Takahashi, M	1
Kehrberg, G; Moldenhauer, H; Rose, H; Saul, G; Wolf, G	1
Adams, GE	1
Brown, JM; Yu, NY	1
Brown, JM; Eifel, PJ	1
Battistella, R; McClelland, RA; Michaels, HB; Rauth, AM	1
Blanke, G; Luscher, G; Streffer, C; Tamulevicius, P	1
Hinchliffe, M; McNally, NJ	1
Coleman, CN; Phillips, TL; Urtasun, RC; Wasserman, TH	1
Denekamp, J; Fowler, JF; Williams, MV	1
Nelson, JS; VonGerichten, D; Wasserman, TH	1
Brown, JM; White, RA; Workman, P	1
Brown, DM; Brown, JM; Lee, WW; Yu, NY	1
Wasserman, TH	1
Siemann, DW	1
Streffer, C; Tamulevicius, P	1
Abe, M; Iwai, H; Matsuno, E; Sasai, K; Shibamoto, Y	1
MacPhail, S; Skov, KA	1
Giandomenico, AR; Iyengar, CW; Koch, CJ	1
Giuliano, J; Lee, DJ; Moini, M; Westra, WH	1
Akuta, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M	1
Battino, M; Breccia, A; Ferri, E; Gattavecchia, E; Genova, ML; Lenaz, G; Littarru, GP	1
Chin, LK; Hofstrand, PD; Rasey, JS; Tewson, TJ	1
Glaholm, J; Watkinson, JC	1
Chen, Q; Deng, X; He, F; Huang, Y; Li, GC; Ling, CC; Liu, Y; Minami, A; Sun, X; Wen, B; Xing, L; Zanzonico, PB	1
Aguilera, TA; Giaccia, AJ	1

Reviews

11 review(s) available for etanidazole and misonidazole

Article	Year
Pharmacokinetics and subcellular localization of radiosensitizers. BJR supplement, 1992, Volume: 24 Topics: Etanidazole; Humans; Hydrogen-Ion Concentration; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1992
[Radiosensitizer: hypoxic cell radiosensitizer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2 Topics: Animals; DNA; Dogs; Etanidazole; Hydroxamic Acids; Hydroxylation; Intercalating Agents; Lethal Dose 50; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Thymine	1989
Hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer. An overview. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Alkylating Agents; Animals; Cell Survival; Drug Synergism; Etanidazole; Hypoxia; Misonidazole; Neoplasms, Experimental; Nitrofurans; Nitrofurazone; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents; Structure-Activity Relationship	1986
Biochemistry of reduction of nitro heterocycles. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Animals; Buthionine Sulfoximine; Catalase; Cell Division; Cell Survival; Etanidazole; Free Radicals; Glucose; Glutathione; Glycolysis; Hexosephosphates; Humans; Hypoxia; Methionine Sulfoximine; Microbodies; Microsomes; Misonidazole; Mitochondria; Nitroimidazoles; Oxidation-Reduction; Pentoses; Peroxidases; Sulfhydryl Compounds	1986
Sensitizers and radiation dose fractionation: results and interpretations. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Combined Modality Therapy; Etanidazole; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage	1986
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
[Intensification of cytostatic action by radiosensitizers--a review of the present status of chemosensitization]. Radiobiologia, radiotherapia, 1984, Volume: 25, Issue:2 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cricetinae; Cyclophosphamide; Doxorubicin; Etanidazole; Lomustine; Melphalan; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Clinical Trials as Topic; Combined Modality Therapy; Dexamethasone; Drug Evaluation; Etanidazole; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Hypoxic sensitizer and cytotoxin for head and neck cancer. Annals of the Academy of Medicine, Singapore, 1996, Volume: 25, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Hypoxia; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Etanidazole; Head and Neck Neoplasms; Humans; Hyperbaric Oxygenation; Mice; Microelectrodes; Misonidazole; Oxygen Consumption; Radiation Tolerance; Radiation-Sensitizing Agents; Survival Rate; Tirapazamine; Treatment Outcome; Triazines	1996

Trials

7 trial(s) available for etanidazole and misonidazole

Article	Year
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Clinical Trials as Topic; Combined Modality Therapy; Dexamethasone; Drug Evaluation; Etanidazole; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Dose-response relationships for human tumors: implications for clinical trials of dose modifying agents. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Clinical Trials as Topic; Dose-Response Relationship, Radiation; Etanidazole; Humans; Mice; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Neuropathy of nitroimidazole radiosensitizers: clinical and pathological description. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Etanidazole; Humans; Misonidazole; Nervous System Diseases; Nitroimidazoles; Radiation-Sensitizing Agents; Sural Nerve	1984
Hypoxic cell radiosensitizers--present and future. International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:6 Topics: Animals; Central Nervous System; Clinical Trials as Topic; Etanidazole; Humans; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1981

Other Studies

55 other study(ies) available for etanidazole and misonidazole

Article	Year
Next-Generation Hypoxic Cell Radiosensitizers: Nitroimidazole Alkylsulfonamides. Journal of medicinal chemistry, 2018, 02-08, Volume: 61, Issue:3 Topics: Animals; Cell Hypoxia; Cell Survival; Drug Discovery; Female; HCT116 Cells; Humans; Mice; Nitroimidazoles; Radiation-Sensitizing Agents; Tissue Distribution; Xenograft Model Antitumor Assays	2018
Modification of alkylating agent induced cell kill by 2-nitroimidazoles in unclamped and clamped SC 9L tumors. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cell Survival; Cyclophosphamide; Etanidazole; Ifosfamide; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344	1992
Protection against light-activated photofrin II killing of tumor cells by nitroimidazoles. Radiation research, 1992, Volume: 130, Issue:1 Topics: Animals; Dihematoporphyrin Ether; Drug Interactions; Etanidazole; Hematoporphyrins; Lasers; Mice; Misonidazole; Nitroimidazoles; Photochemotherapy; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1992
2-Nitroimidazole potentiation of nitrosourea induced cytotoxicity in subcutaneous implants of rat 9L brain tumor cells. Journal of neuro-oncology, 1991, Volume: 11, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Nitroimidazoles; Rats; Rats, Inbred F344; Streptozocin; Tumor Stem Cell Assay	1991
Addition of 2-nitroimidazole radiosensitizers to cis-diamminedichloroplatinum(II) with radiation and with or without hyperthermia in the murine FSaIIC fibrosarcoma. Cancer research, 1990, May-01, Volume: 50, Issue:9 Topics: Animals; Cell Survival; Cisplatin; Combined Modality Therapy; Drug Therapy, Combination; Etanidazole; Fibrosarcoma; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1990
KIH-802, an acetohydroxamic acid derivative of 2-nitroimidazole, as a new potent hypoxic cell radiosensitizer: radiosensitizing activity, acute toxicity, and pharmacokinetics. Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:2 Topics: Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Etanidazole; Female; Hydroxamic Acids; Hypoxia; Injections, Intravenous; Lethal Dose 50; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1990
Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations. International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5 Topics: Animals; Carmustine; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Rats; Rats, Inbred F344; Structure-Activity Relationship	1990
Effect of acidic pH on radiosensitization of FSaIIC cells in vitro by misonidazole, etanidazole, or cis-diamminedichloroplatinum (II). Radiation research, 1990, Volume: 124, Issue:1 Topics: Animals; Cell Line; Cell Survival; Cisplatin; Etanidazole; Fibrosarcoma; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1990
[Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer]. Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:13 Topics: Cell Hypoxia; Etanidazole; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1990
Evaluation of nitroimidazole hypoxic cell radiosensitizers in a human tumor cell line high in intracellular glutathione. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Cell Line; Drug Evaluation, Preclinical; Etanidazole; Glutathione; Humans; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989
Effects of nitroimidazoles on neuronal cells in vitro. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Axons; Cell Line; Etanidazole; Intermediate Filaments; Mice; Misonidazole; Neurons; Nitroimidazoles; Radiation-Sensitizing Agents; Rats	1989
Oncogenic transforming potential of nitroimidazole radiosensitizers. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Etanidazole; Mice; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1989
Radiosensitizing and cytotoxic effects of nitroimidazoles in CHO cells expressing elevated levels of glutathione-S-transferase. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Etanidazole; Glutathione Transferase; Melphalan; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1989
Addition of misonidazole, etanidazole, or hyperthermia to treatment with fluosol-DA/carbogen/radiation. Journal of the National Cancer Institute, 1989, Jun-21, Volume: 81, Issue:12 Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Drug Combinations; Etanidazole; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental	1989
Radiosensitization by a new nucleoside analogue: 1-[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl-2-nitroimidazole (RP-170). International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:3 Topics: Animals; Cell Survival; Combined Modality Therapy; Etanidazole; In Vitro Techniques; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1989
A new, potent 2-nitroimidazole nucleoside hypoxic cell radiosensitizer, RP170. Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:11 Topics: Animals; Cell Survival; Etanidazole; Female; Lethal Dose 50; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989
Bone marrow toxicity of total-body irradiation combined with radiosensitizers. Radiation research, 1989, Volume: 120, Issue:2 Topics: Animals; Bone Marrow; Dogs; Etanidazole; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Whole-Body Irradiation	1989
Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice. International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:2 Topics: Amifostine; Animals; Etanidazole; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents; Radiation-Sensitizing Agents	1988
Concentrations achieved in human tumors after administration of misonidazole, SR-2508 and Ro 03-8799. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Aged; Etanidazole; Female; Humans; Male; Middle Aged; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1986
A comparison of tumor and normal tissue levels of acidic, basic and neutral 2-nitroimidazole radiosensitizers in mice. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Etanidazole; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Tissue Distribution	1986
Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Etanidazole; Glutathione; Humans; Hydrogen Peroxide; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Pyrazoles; Radiation-Sensitizing Agents	1986
The effect of hypoxic cell sensitizers at different irradiation dose rates. Radiation research, 1987, Volume: 109, Issue:3 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Etanidazole; Lung; Misonidazole; Nitroimidazoles; Regression Analysis	1987
[Present status of hypoxic cell sensitizers and PLDR inhibitors]. Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:13 Topics: Animals; Cell Cycle; Cell Line; Etanidazole; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage	1987
Interactions of hyperthermia with hypoxic cell sensitisers. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 109 Topics: Animals; Combined Modality Therapy; Etanidazole; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1988
[Development of new hypoxic cell radiosensitizer in Japan]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:13 Topics: Animals; Dogs; Drug Evaluation, Preclinical; Etanidazole; Hydroxamic Acids; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1988
Relationship between the neurotoxicity of the hypoxic cell radiosensitizer SR 2508 and the pharmacokinetic profile. Cancer research, 1987, Jan-01, Volume: 47, Issue:1 Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Etanidazole; Humans; Kinetics; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents	1987
Selective enhancement of hypoxic cell killing by melphalan via thiol depletion: in vitro studies with hypoxic cell sensitizers and buthionine sulfoximine. Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1 Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Etanidazole; Melphalan; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Sulfhydryl Compounds	1985
The in vitro sensitivity of chronically hypoxic EMT6/SF cells to X-radiation and hypoxic cell radiosensitizers. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:1 Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Etanidazole; Female; Mammary Neoplasms, Experimental; Mice; Misonidazole; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Rats; Sulfhydryl Compounds; X-Rays	1985
Testing of new hypoxic cell sensitizers in vivo. Radiation research, 1982, Volume: 91, Issue:1 Topics: Animals; Drug Evaluation, Preclinical; Etanidazole; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1982
A comparison of the cytological effects of three hypoxic cell radiosensitizers. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:7 Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Etanidazole; Lung; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Sister Chromatid Exchange	1982
Clinical perspectives for the use of new hypoxic cell sensitizers. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:9 Topics: Animals; Cyclophosphamide; Dogs; Drug Therapy, Combination; Etanidazole; Humans; Melphalan; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Solubility	1982
[Studies in radiosensitizing effects of misonidazole and SR-2508 on experimental animal tumors]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1983, Feb-25, Volume: 43, Issue:2 Topics: Animals; Etanidazole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1983
Sensitization of normal and malignant tissue to cyclophosphamide by nitroimidazoles with different partition coefficients. British journal of cancer, 1984, Volume: 49, Issue:1 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Etanidazole; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Inhibition of X-ray-induced potentially lethal damage (PLD) repair in aerobic plateau-phase Chinese hamster cells by misonidazole. Radiation research, 1984, Volume: 97, Issue:1 Topics: Aerobiosis; Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Etanidazole; Female; Misonidazole; Nitroimidazoles; Ovary; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Time Factors	1984
[Recent advances in hypoxic cell radiosensitizer]. Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:13 Topics: Animals; Cells, Cultured; Etanidazole; Maleates; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents	1983
Clinical trials of radiosensitizers: what should we expect? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:3 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Dogs; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Etanidazole; Humans; Kinetics; Lethal Dose 50; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Radiosensitizers: a conference preview. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Etanidazole; Glutathione; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Pharmacokinetics and toxicology of continuously infused nitroimidazoles. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Brain; Etanidazole; Female; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1984
The oxygen dependence of the reduction of nitroimidazoles in a radiolytic model system. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Acetophenones; Cobalt Radioisotopes; Etanidazole; Gamma Rays; Metronidazole; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Oxygen; Radiation-Sensitizing Agents	1984
The effects of radiosensitizers on intermediary metabolism in vivo. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenocarcinoma; Animals; Dihydroxyacetone Phosphate; Etanidazole; Glycerophosphates; Hydroxybutyrates; Lactates; Liver; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Pyruvates; Radiation-Sensitizing Agents	1984
A comparison of the ability of some radiosensitizers undergoing clinical trials to act as chemosensitizers. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Etanidazole; Fibrosarcoma; Melphalan; Mice; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents	1984
The pharmacokinetics and tumor and neural tissue penetrating properties of SR-2508 and SR-2555 in the dog--hydrophilic radiosensitizers potentially less toxic than misonidazole. Radiation research, 1980, Volume: 84, Issue:3 Topics: Administration, Oral; Animals; Biological Availability; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Etanidazole; Female; Injections, Intravenous; Kinetics; Male; Misonidazole; Neoplasms; Nervous System; Nitroimidazoles; Radiation-Sensitizing Agents; Structure-Activity Relationship	1980
SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use. International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:6 Topics: Animals; Carcinoma; Cell Line; Central Nervous System; Cricetinae; Dogs; Etanidazole; Female; In Vitro Techniques; Lipid Metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; X-Rays	1981
Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers. British journal of cancer, 1982, Volume: 45, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanidazole; Female; Leukocyte Count; Lomustine; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Sarcoma, Experimental	1982
Metabolic studies and neurotoxicity in tumors and brain of mice after hypoxic cell sensitizers. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Adenosine Triphosphate; Animals; Brain; Etanidazole; Glucose; Male; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1994
Radiosensitizing activity and pharmacokinetics of multiple dose administered KU-2285 in peripheral nerve tissue in mice. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Animals; Carcinoma, Squamous Cell; Etanidazole; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents	1994
Low concentrations of nitroimidazoles: effective radiosensitizers at low doses. International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1 Topics: Animals; CHO Cells; Cricetinae; Etanidazole; Hypoxia; In Vitro Techniques; Misonidazole; Nimorazole; Radiation-Sensitizing Agents	1994
Bioreductive metabolism of AF-2[2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles. Implications for use as hypoxic cell markers. Biochemical pharmacology, 1993, Sep-14, Volume: 46, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Drug Interactions; Etanidazole; Furylfuramide; Glucose; Guinea Pigs; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Oxygen Consumption; Rats; Tumor Cells, Cultured	1993
The radiosensitizing effects of hypoxic cell sensitizer on SCCVII tumors in mice evaluated by highly accurate colony formation assay assisted by microcomputer. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1996, Volume: 56, Issue:14 Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Etanidazole; Male; Mice; Mice, Inbred C3H; Microcomputers; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay	1996
Mitochondrial respiratory chain features after gamma-irradiation. Free radical research, 1997, Volume: 26, Issue:5 Topics: Animals; Cattle; Chromatography, Gas; Chromatography, High Pressure Liquid; Electron Transport; Etanidazole; Gamma Rays; Misonidazole; Mitochondria, Heart; Nitroimidazoles; Spectrophotometry; Succinate Dehydrogenase; Ubiquinone	1997
Characterization of [18F]fluoroetanidazole, a new radiopharmaceutical for detecting tumor hypoxia. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:6 Topics: Animals; Binding Sites; Blood-Brain Barrier; Cell Hypoxia; Chromatography, High Pressure Liquid; Contrast Media; Cricetinae; Cricetulus; Etanidazole; Female; Fibroblasts; Fibrosarcoma; Fluorine Radioisotopes; Glioma; Lung; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Rats; Sarcoma, Experimental; Time Factors; Tissue Distribution; Tumor Cells, Cultured	1999
Developments in radiotherapy and adjuvant chemotherapy for head and neck cancer. Clinical otolaryngology and allied sciences, 2003, Volume: 28, Issue:1 Topics: Antineoplastic Agents; Cell Hypoxia; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose Fractionation, Radiation; Etanidazole; Head and Neck Neoplasms; Humans; Misonidazole; Niacinamide; Vasodilator Agents	2003
Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. Cancer research, 2008, Oct-15, Volume: 68, Issue:20 Topics: Animals; Antigens, Neoplasm; Arabinofuranosyluracil; Autoradiography; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Etanidazole; Female; Gene Expression; Green Fluorescent Proteins; Herpesvirus 1, Human; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Immunohistochemistry; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Thymidine Kinase; Tissue Distribution; Transplantation, Heterologous	2008
The end of the hypoxic EPOch. International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5 Topics: Anemia; Blood Transfusion; Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Erythropoietin; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Misonidazole; Radiation-Sensitizing Agents; Receptors, Erythropoietin; Treatment Failure; Uterine Cervical Neoplasms	2015