etanidazole and azomycin

etanidazole has been researched along with azomycin in 145 studies

Research

Studies (145)

Timeframe	Studies, this research(%)	All Research%
pre-1990	82 (56.55)	18.7374
1990's	52 (35.86)	18.2507
2000's	8 (5.52)	29.6817
2010's	3 (2.07)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Stratford, MR	1
Buswell, L; Coleman, CN; Noll, L; Riese, N; Rose, MA	1
Abe, M; Oya, N; Sasai, K; Shibamoto, Y; Streffer, C	1
Abe, M; Iwai, H; Kitakabu, Y; Nishimoto, S; Oya, N; Sasai, K; Shibamoto, Y; Takahashi, M; Yoshizawa, T	1
Miyata, Y; Mori, T; Murayama, C; Sakaguchi, M; Sato, C; Shoji, T; Suzuki, A; Suzuki, T; Tanabe, Y	1
Coleman, CN; Cosmatos, D; Davis, LW; Lee, DJ; Marcial, VA; Phillips, TL; Rubin, P; Wasserman, TH	1
Alexander, E; Buswell, L; Coleman, CN; Hurwitz, SJ; Kramer, RA; Loeffler, JS; Neben, TY; Riese, N; Shargel, L	1
Alexander, E; Buswell, L; Coleman, CN; Harris, JR; Howes, AE; Kramer, RA; Loeffler, JS; Noll, L; Riese, N; Wen, P	1
Charreau, I; Chassagne, D; Eschwege, F; Malaise, EP; Sancho-Garnier, H	2
Bertoni, F; Breccia, A; Busutti, L; Falcone, F; Ferri, E	1
Degraff, WG; Garg, PK; Garg, S; Mitchell, JB; Zalutsky, MR	1
Moore, SK; Wallen, CA; Wheeler, KT	1
Bump, EA; Cerce, BA; Coleman, CN; McGinnis, DJ	1
Hall, EJ; Hei, TK	2
Chapman, JD; McPhee, MS; Santus, R; Stobbe, CC	1
Basas, RA; Ling, CC; Wong, RS	1
LaCreta, FP; O'Dwyer, PJ	1
Brown, TD; Burris, HA; Havlin, KA; O'Rourke, TJ; Rodriguez, GI; Wall, JG; Weiss, GR	1
Bubley, G; Coleman, CN; Eder, JP; Frei, E; Herman, TS; Holden, SA; Tanaka, J; Teicher, BA	1
Alberti, D; Arzoomanian, RZ; Bailey, H; Mulcahy, RT; Rozental, JM; Tombes, MB; Trump, DL; Tutsch, KD; Wilding, G	1
Brown, DQ; Curran, WJ; Evans, SM; Hanks, G; Helfand, S; LaCreta, F; VanWinkle, T	1
Herman, TS; Holden, SA; Teicher, BA	1
Coleman, N; Cosmatos, D; Davis, L; Lee, DJ; Marcial, V; Phillips, T; Stetz, J; Wasserman, TH	1
Bleehen, NM; Maughan, TS; Newman, HF; Stenning, S; Ward, R; Workman, P	1
Brown, JM; Cribbs, R; Hirst, VK; Luu, YH; Stone, HB	1
Hisanaga, Y; Kagiya, T; Kitakabu, Y; Nishimoto, S; Sasai, K; Shibamoto, Y; Shimokawa, K; Takahashi, M; Wang, J; Zhou, L	1
Bubley, G; Coleman, CN; Frei, E; Herman, TS; Shulman, L; Teicher, BA	1
Wallen, CA; Wheeler, KT; Wong, KH	2
Guichard, ME; Lespinasse, F; Taghian, A	1
Basas, RD; Ling, CC; Wong, RS	1
Herman, TS; Holden, SA; Jones, SM; Pfeffer, MR; Teicher, BA	1
Abe, M; Hori, H; Inayama, S; Nagasawa, H; Sasai, K; Shibamoto, Y; Shibata, T; Takahashi, M; Zhou, L	1
Bleehen, NM; Maughan, TS; Newman, HF; Ward, R; Workman, P	2
Chapnick, RM; Herman, TS; Kalick, GS; Khandekar, V; Pfeffer, MR; Rabow, A; Teicher, BA	1
Mori, T; Murayama, C	2
Hirst, DG	1
Coleman, CN; Halsey, J; Hancock, S; Noll, L; Phillips, TL; Urtasun, RC; Wasserman, TH	1
Coldwell, DM; Coldwell, SG; Huff, J; Marcellus, H	1
Workman, P	1
DeGraff, WG; Gamson, J; Mitchell, JB; Russo, A	1
abd el Baki, H; Akoush, H; Awwad, HK; el Badawy, S; el Moneim Osman, A; Fairchild, K; Zaghloul, M	1
Coleman, CN; Harris, JR; Howes, AE; Kramer, RA; Noll, L; Zakar, J	1
Bonnay, M; Guichard, M; Lespinasse, F; Malaise, EP; Thomas, C	1
Calderwood, SK; Coleman, CN; Stevenson, MA	1
Hickson, ID; Robson, CN; Stephens, M; Stratford, IJ	1
Howes, AE; Kramer, RA; Montoya, VP; Soble, M	1
Albright, N; DeGraff, WG; Mitchell, JB; Phillips, TL; Rajpal, R; Russo, A	1
Mori, T	1
Herman, TS; Holden, SA; Jones, SM; Teicher, BA	1
Miyata, Y; Mori, T; Murayama, C; Sakaguchi, M; Suzuki, A; Suzuki, T; Tanabe, Y; Tanaka, N	1
Abe, M; Kagiya, T; Nishimoto, S; Sasai, K; Shibamoto, Y; Takahashi, M; Wang, J; Zhou, L	1
Allalunis-Turner, J; Applebaum, FR; Chapman, JD; Deeg, HJ; Graham, T; Shields, AF; Storb, R	1
Bleehen, NM; Maughan, TS; Newman, HF; Workman, P	1
Chapman, JD; Kanclerz, A	1
Bleehen, NM; Newman, HF; Ward, R; Workman, P	2
Edwards, MS; Gordon, DG	1
Adams, GE; Stratford, IJ	1
Astor, MB; Biaglow, JE; Clark, EP; Epp, ER; Hall, EJ; Roizen-Towle, L; Varnes, ME	1
Bleehen, NM; Newman, HF; Workman, P	2
Hill, RP	1
Durand, RE; Harrison, I; Palcic, B; Skarsgard, LD	1
Lam, KN; Luu, YH; Stone, HB	1
Bennett, MH; Des Rochers, C; Dische, S; Dunphy, EP; Minchinton, AI; Orchard, RA; Saunders, MI; Stratford, MR	1
Minchinton, AI; Stratford, MR	1
Dobson, PP; Fornace, AJ; Kinsella, TJ; Mitchell, JB; Russo, A	1
Carmichael, J; DeGraff, W; Mitchell, JB; Phillips, TL; Rajpal, RK; Russo, A	1
Biaglow, JE; Clark, EP; Donahue, LL; Epp, ER; Tuttle, SW; Varnes, ME	1
Varghese, AJ; Whitmore, GF	1
de Graff, W; Glatstein, E; Mitchell, JB; Phillips, TL; Russo, A	1
Bussanich, N; Gallie, B; Kumi, C; Palcic, B; Rogers, B; Rootman, J	1
Ling, CC; Schell, MC; Spiro, IJ; Stickler, R	1
Biscay, P; Guichard, M; Lespinasse, F; Malaise, EP	1
Ward, R; Workman, P	1
Dennis, MF; Watts, ME; Woodcock, M	1
Abe, M; Fushiki, M; Nishidai, T; Ono, K; Sasai, K; Shibamoto, Y; Takahashi, M; Tsutsui, K	1
Freedman, LS; Workman, P	1
Bleehen, NM; Honess, DJ; Ward, R; Wasserman, TH; Workman, P	1
Wasserman, TH	2
Bleehen, NM; Walton, MI; Workman, P	1
Berenbaum, MC	1
Brown, JM	3
Coleman, CN; Halsey, J; Hancock, S; Hirst, VK; Phillips, TL; Urtasun, RC; Wasserman, TH	1
Blaschke, T; Coleman, CN; Cox, RS; Halsey, J; Hancock, S; Hirst, VK; Howes, AE; Pajak, T; Urtasun, RC; Wasserman, TH	1
Roizin-Towle, L	1
Coleman, CN	1
Dische, S	1
DeGraff, W; Gamson, J; McPherson, S; Mitchell, JB; Russo, A; Zabell, A	1
Harris, JW; Shrieve, DC	1
Sinesi, MS; Stone, HB	1
Geard, CR; Rutledge-Freeman, MH; Spunberg, JJ	1
Abe, M; Hamanaka, D; Hiraoka, M; Nishidai, T; Ono, K; Takahashi, M	1
Brown, JM; Hazlehurst, JL; Hirst, DG	1
Brown, DM; Brown, JM; Dionet, C	1
Abe, M; Nishidai, T; Ono, K; Shibamoto, Y; Takahashi, M	1
Biaglow, JE; Meltzer, HL; Roizin-Towle, L; Varnes, ME	1
Kehrberg, G; Moldenhauer, H; Rose, H; Saul, G; Wolf, G	1
Adams, GE	1
Brown, JM; Yu, NY	2
Brown, JM; Eifel, PJ	1
Battistella, R; McClelland, RA; Michaels, HB; Rauth, AM	1
Blanke, G; Luscher, G; Streffer, C; Tamulevicius, P	1
Hinchliffe, M; McNally, NJ	1
Brown, JM; Hazlehurst, JL; Hirst, DG; Horsman, MR	1
Coleman, CN; Phillips, TL; Urtasun, RC; Wasserman, TH	1
Denekamp, J; Fowler, JF; Williams, MV	1
Nelson, JS; VonGerichten, D; Wasserman, TH	1
Coleman, CN; Halsey, J; Hancock, S; Harris, JW; Hirst, VK; Urtasun, RC; Wasserman, TH	1
Brown, JM; White, RA; Workman, P	1
Brown, DM; Brown, JM; Lee, WW; Yu, NY	1
Siemann, DW	1
Abe, M; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Sugiyama, T	1
Streffer, C; Tamulevicius, P	1
Abe, M; Ishigaki, T; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T	1
Abe, M; Iwai, H; Matsuno, E; Sasai, K; Shibamoto, Y	1
el Gamoussi, R; Guichard, M; Stratford, IJ	1
Giandomenico, AR; Iyengar, CW; Koch, CJ	1
Harwell, L; Koch, CJ; Lord, EM	1
Abe, M; Oya, N; Sasai, K; Shibamoto, Y; Sugiyama, T	1
el Gamoussi, R; Guichard, M; Prade, M; Stratford, IJ; Threadgill, MD	1
Miyata, Y; Mori, T; Murayama, C; Nishio, A; Sakaguchi, M; Sato, C; Shoji, T; Suzuki, A; Suzuki, T; Tanabe, Y	1
Akuta, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M	1
Battino, M; Breccia, A; Ferri, E; Gattavecchia, E; Genova, ML; Lenaz, G; Littarru, GP	1
Skarsgard, LD; Wouters, BG	1
De Bast, M; Gillart, J; Grégoire, V; Labar, D; Mahy, P	1
Le, QT	1
Koch, CJ	1
Humm, JL; Li, GC; Li, XF; Ling, CC; Russell, J; Sun, X; Urano, M; Xing, L	1
Chen, Q; Deng, X; He, F; Huang, Y; Li, GC; Ling, CC; Liu, Y; Minami, A; Sun, X; Wen, B; Xing, L; Zanzonico, PB	1
Eskola, O; Grönroos, TJ; Komar, G; Lehtiö, K; Minn, H; Seppänen, M; Solin, O; Tuomela, J	1
Burke, SA; Carlin, S; Ling, CC; Russell, J; Wen, B; Yang, KM	1
Cho, H; Koutcher, JA; Li, XF; Ling, CC; Lupu, ME; Russell, J; Yang, KM	1
Forsback, S; Heinonen, SE; Knuuti, J; Laine, VJ; Roivainen, A; Saraste, A; Saukko, P; Silvola, JM; Ylä-Herttuala, S	1
Carlin, S; Humm, JL	1
Ackerley, DF; Anderson, RF; Ashoorzadeh, A; Copp, JN; Flanagan, JU; Guise, CP; Mowday, AM; Patterson, AV; Rich, MH; Smaill, JB; Williams, EM	1

Reviews

14 review(s) available for etanidazole and azomycin

Article	Year
Pharmacokinetics and subcellular localization of radiosensitizers. BJR supplement, 1992, Volume: 24 Topics: Etanidazole; Humans; Hydrogen-Ion Concentration; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1992
Pharmacology and clinical investigation of SR-2508 (etanidazole). Cancer treatment and research, 1991, Volume: 58 Topics: Etanidazole; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1991
New anticancer agents. Cancer chemotherapy and biological response modifiers, 1991, Volume: 12 Topics: Alkaloids; Animals; Antineoplastic Agents; Azacitidine; Biphenyl Compounds; Chrysenes; Deoxycytidine; Echinomycin; Epirubicin; Etanidazole; Flavonoids; Gemcitabine; Guanidines; Humans; Idarubicin; Menogaril; Mitoguazone; Neoplasms; Nitroimidazoles; Nogalamycin; Organoplatinum Compounds; Paclitaxel; Pentostatin; Polymers; Propylene Glycols; Ribavirin; Sulfonylurea Compounds; Trimetrexate; Vidarabine Phosphate	1991
[Radiosensitizer: hypoxic cell radiosensitizer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2 Topics: Animals; DNA; Dogs; Etanidazole; Hydroxamic Acids; Hydroxylation; Intercalating Agents; Lethal Dose 50; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Thymine	1989
Hypoxia-mediated nitro-heterocyclic drugs in the radio- and chemotherapy of cancer. An overview. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Alkylating Agents; Animals; Cell Survival; Drug Synergism; Etanidazole; Hypoxia; Misonidazole; Neoplasms, Experimental; Nitrofurans; Nitrofurazone; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents; Structure-Activity Relationship	1986
Biochemistry of reduction of nitro heterocycles. Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1 Topics: Animals; Buthionine Sulfoximine; Catalase; Cell Division; Cell Survival; Etanidazole; Free Radicals; Glucose; Glutathione; Glycolysis; Hexosephosphates; Humans; Hypoxia; Methionine Sulfoximine; Microbodies; Microsomes; Misonidazole; Mitochondria; Nitroimidazoles; Oxidation-Reduction; Pentoses; Peroxidases; Sulfhydryl Compounds	1986
Sensitizers and radiation dose fractionation: results and interpretations. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Combined Modality Therapy; Etanidazole; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage	1986
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
[Intensification of cytostatic action by radiosensitizers--a review of the present status of chemosensitization]. Radiobiologia, radiotherapia, 1984, Volume: 25, Issue:2 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cricetinae; Cyclophosphamide; Doxorubicin; Etanidazole; Lomustine; Melphalan; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Clinical Trials as Topic; Combined Modality Therapy; Dexamethasone; Drug Evaluation; Etanidazole; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Imaging of tumor hypoxia to predict treatment sensitivity. Current pharmaceutical design, 2008, Volume: 14, Issue:28 Topics: Animals; Cell Hypoxia; Drug Resistance, Neoplasm; Etanidazole; Humans; Hydrocarbons, Fluorinated; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals	2008
PET of hypoxia: current and future perspectives. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:8 Topics: Etanidazole; Humans; Hydrocarbons, Fluorinated; Hypoxia; Nitroimidazoles; Positron-Emission Tomography; Radioactive Tracers; Triazoles	2012

Trials

22 trial(s) available for etanidazole and azomycin

Article	Year
The efficacy of pharmacokinetic monitoring and dose modification of etanidazole on the incidence of neurotoxicity: results from a phase II trial of etanidazole and radiation therapy in locally advanced prostate cancer. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Adenocarcinoma; Combined Modality Therapy; Drug Evaluation; Etanidazole; Humans; Male; Nitroimidazoles; Peripheral Nervous System Diseases; Prostatic Neoplasms; Radiation-Sensitizing Agents	1992
Logistics in designing clinical trials for etanidazole (SR 2508): an RTOG experience. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Research Design	1992
Final report of the phase I trial of continuous infusion etanidazole (SR 2508): a Radiation Therapy Oncology Group study. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Brachytherapy; Combined Modality Therapy; Drug Evaluation; Etanidazole; Female; Humans; Infusions, Intravenous; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1992
First analysis of tumor regression for the European randomized trial of etanidazole combined with radiotherapy in head and neck carcinomas. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Etanidazole; Female; Head and Neck Neoplasms; Humans; Male; Nitroimidazoles; Radiation-Sensitizing Agents	1992
Kinetic uptake of etanidazole in lung carcinoma and normal tissue in vivo. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Aged; Carcinoma, Bronchogenic; Combined Modality Therapy; Etanidazole; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents; Reference Values	1992
Pharmacology and clinical investigation of SR-2508 (etanidazole). Cancer treatment and research, 1991, Volume: 58 Topics: Etanidazole; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1991
A phase I study of SR-2508 and cyclophosphamide administered by intravenous injection. Cancer research, 1991, Feb-15, Volume: 51, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Etanidazole; Female; Humans; Injections, Intravenous; Male; Middle Aged; Nitroimidazoles	1991
Progress report of a phase II and a phase III trial with etanidazole (SR-2508): a multicentre European study. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Europe; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Clinical trials with etanidazole (SR-2508) by the Radiation Therapy Oncology Group (RTOG). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Evaluation; Etanidazole; Head and Neck Neoplasms; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1991
The combination of multiple doses of etanidazole and pimonidazole in 48 patients: a toxicity and pharmacokinetic study. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1 Topics: Adult; Aged; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Combinations; Etanidazole; Female; Humans; Male; Middle Aged; Neoplasms; Nervous System Diseases; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Abnormal clinical pharmacokinetics of the developmental radiosensitizers pimonidazole (Ro 03-8799) and etanidazole (SR 2508). International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5 Topics: Aged; Clinical Trials as Topic; Etanidazole; Humans; Male; Middle Aged; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1990
Final report of the phase I trial of the hypoxic cell radiosensitizer SR 2508 (etanidazole) Radiation Therapy Oncology Group 83-03. International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2 Topics: Adult; Canada; Combined Modality Therapy; Drug Evaluation; Etanidazole; Humans; Infusions, Intravenous; Multicenter Studies as Topic; Neoplasms; Nitroimidazoles; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents; United States	1990
Initial results of a phase I trial of continuous infusion SR 2508 (etanidazole): a radiation therapy oncology group study. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Brachytherapy; Combined Modality Therapy; Drug Evaluation; Etanidazole; Humans; Infusions, Intravenous; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1989
A multiple dose study of the combined radiosensitizers Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Drug Combinations; Etanidazole; Humans; Neoplasms; Nitroimidazoles; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents	1989
Hypoxic cell radiosensitizers: illusion or elusion? International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:3 Topics: Clinical Trials as Topic; Drug Therapy, Combination; Etanidazole; Humans; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1988
Sensitizers and protectors in radiotherapy. Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl Topics: Amifostine; Animals; Aziridines; Clinical Trials as Topic; Drug Evaluation; Etanidazole; Glutathione; Humans; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy	1985
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Clinical trials with hypoxic cell sensitizers: time to retrench or time to push forward? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Clinical Trials as Topic; Combined Modality Therapy; Dexamethasone; Drug Evaluation; Etanidazole; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Dose-response relationships for human tumors: implications for clinical trials of dose modifying agents. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Clinical Trials as Topic; Dose-Response Relationship, Radiation; Etanidazole; Humans; Mice; Misonidazole; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Neuropathy of nitroimidazole radiosensitizers: clinical and pathological description. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Etanidazole; Humans; Misonidazole; Nervous System Diseases; Nitroimidazoles; Radiation-Sensitizing Agents; Sural Nerve	1984
Hypoxic cell radiosensitizers--present and future. International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:6 Topics: Animals; Central Nervous System; Clinical Trials as Topic; Etanidazole; Humans; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1981

Other Studies

114 other study(ies) available for etanidazole and azomycin

Article	Year
Radiosensitization efficacy of KU-2285, RP-170 and etanidazole at low radiation doses: assessment by in vitro cytokinesis-block micronucleus assay. International journal of radiation biology, 1992, Volume: 61, Issue:4 Topics: Animals; Cell Hypoxia; Dose-Response Relationship, Drug; Etanidazole; Mice; Micronucleus Tests; Nitroimidazoles; Nucleosides; Radiation Dosage; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1992
Pharmacokinetics of fluorinated 2-nitroimidazole hypoxic cell radiosensitizers in murine peripheral nervous tissue. International journal of radiation biology, 1992, Volume: 62, Issue:2 Topics: Animals; Cell Hypoxia; Etanidazole; Female; Half-Life; Mice; Mice, Inbred C3H; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents	1992
Radiosensitization by 2-nitroimidazole nucleoside analog RP-170: radiosensitizing effects under both intravenous and oral administration. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Administration, Oral; Animals; Combined Modality Therapy; Etanidazole; Female; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains	1992
Distribution of etanidazole into human brain tumors: implications for treating high grade gliomas. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Brain Neoplasms; Combined Modality Therapy; Drug Evaluation; Etanidazole; Humans; Infusions, Intravenous; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1992
4-Fluorobenzylamine and phenylalanine methyl ester conjugates of 2-nitroimidazole: evaluation as hypoxic cell radiosensitizers. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3 Topics: Animals; Cell Hypoxia; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Drug Evaluation; Etanidazole; In Vitro Techniques; Nitroimidazoles; Radiation-Sensitizing Agents	1992
Modification of alkylating agent induced cell kill by 2-nitroimidazoles in unclamped and clamped SC 9L tumors. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cell Survival; Cyclophosphamide; Etanidazole; Ifosfamide; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344	1992
Sensitization of Chinese hamster ovary cells to melphalan by etanidazole under intermittent hypoxia. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4 Topics: Animals; Cell Hypoxia; Cell Survival; CHO Cells; Cricetinae; Etanidazole; Melphalan; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1992
Oncogenic transforming potential of etanidazole. International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Etanidazole; Mice; Neoplasms, Second Primary; Nitroimidazoles; Radiation-Sensitizing Agents; Risk	1992
Protection against light-activated photofrin II killing of tumor cells by nitroimidazoles. Radiation research, 1992, Volume: 130, Issue:1 Topics: Animals; Dihematoporphyrin Ether; Drug Interactions; Etanidazole; Hematoporphyrins; Lasers; Mice; Misonidazole; Nitroimidazoles; Photochemotherapy; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1992
Enhancement of SR 2508 (etanidazole) radiosensitization by buthionine sulphoximine at low-dose-rate irradiation. International journal of radiation biology, 1991, Volume: 59, Issue:1 Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Hypoxia; Dose-Response Relationship, Radiation; Drug Combinations; Drug Synergism; Etanidazole; In Vitro Techniques; Methionine Sulfoximine; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Modulation of alkylating agents by etanidazole and Fluosol-DA/carbogen in the FSaIIC fibrosarcoma and EMT6 mammary carcinoma. Cancer research, 1991, Feb-15, Volume: 51, Issue:4 Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carbon Dioxide; Carboplatin; Carmustine; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Etanidazole; Fibrosarcoma; Flow Cytometry; Fluorocarbons; Hydroxyethyl Starch Derivatives; Mammary Neoplasms, Experimental; Melphalan; Mice; Nitroimidazoles; Organoplatinum Compounds; Oxygen; Radiation-Sensitizing Agents; Thiotepa	1991
Technique, pharmacokinetics, toxicity, and efficacy of intratumoral etanidazole and radiotherapy for treatment of spontaneous feline oral squamous cell carcinoma. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:4 Topics: Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats; Combined Modality Therapy; Etanidazole; Mouth Neoplasms; Necrosis; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage	1991
Effect of pH, oxygenation, and temperature on the cytotoxicity and radiosensitization by etanidazole. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:4 Topics: Animals; Benzimidazoles; Cell Division; Cell Line; Cell Survival; Etanidazole; Fibrosarcoma; Flow Cytometry; Fluorescent Dyes; Hydrogen-Ion Concentration; Hyperthermia, Induced; Hypoxia; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; Temperature	1991
A comparison of radiosensitization by etanidazole and pimonidazole in mouse tumors. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:5 Topics: Animals; Cell Survival; Combined Modality Therapy; Etanidazole; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1991
A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer. International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:6 Topics: Animals; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etanidazole; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1991
Combination of etanidazole with cyclophosphamide and platinum complexes. Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Cells; Carboplatin; Cell Survival; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Etanidazole; Fibrosarcoma; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Nitroimidazoles; Time Factors	1991
2-Nitroimidazole potentiation of nitrosourea induced cytotoxicity in subcutaneous implants of rat 9L brain tumor cells. Journal of neuro-oncology, 1991, Volume: 11, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Nitroimidazoles; Rats; Rats, Inbred F344; Streptozocin; Tumor Stem Cell Assay	1991
Radiosensitization by the combination of etanidazole (SR-2508) and pimonidazole (Ro 03-8799) in human tumor xenografts. International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:6 Topics: Adenocarcinoma; Animals; Cell Survival; Drug Synergism; Etanidazole; Female; Humans; Melanoma; Mice; Mice, Nude; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rectal Neoplasms	1991
Glutathione depletion and cytotoxicity of buthionine sulphoximine and SR2508 in rodent and human cells. International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:2 Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Drug Synergism; Etanidazole; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Nitroimidazoles; Radiation-Sensitizing Agents	1990
Addition of 2-nitroimidazole radiosensitizers to cis-diamminedichloroplatinum(II) with radiation and with or without hyperthermia in the murine FSaIIC fibrosarcoma. Cancer research, 1990, May-01, Volume: 50, Issue:9 Topics: Animals; Cell Survival; Cisplatin; Combined Modality Therapy; Drug Therapy, Combination; Etanidazole; Fibrosarcoma; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1990
KIH-802, an acetohydroxamic acid derivative of 2-nitroimidazole, as a new potent hypoxic cell radiosensitizer: radiosensitizing activity, acute toxicity, and pharmacokinetics. Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:2 Topics: Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Etanidazole; Female; Hydroxamic Acids; Hypoxia; Injections, Intravenous; Lethal Dose 50; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1990
Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations. International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:5 Topics: Animals; Carmustine; Drug Synergism; Etanidazole; Lomustine; Male; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Nitrosourea Compounds; Rats; Rats, Inbred F344; Structure-Activity Relationship	1990
Effect of acidic pH on radiosensitization of FSaIIC cells in vitro by misonidazole, etanidazole, or cis-diamminedichloroplatinum (II). Radiation research, 1990, Volume: 124, Issue:1 Topics: Animals; Cell Line; Cell Survival; Cisplatin; Etanidazole; Fibrosarcoma; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1990
[Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer]. Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:13 Topics: Cell Hypoxia; Etanidazole; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1990
Tumour radiosensitization by clofibrate and its analogs: possible mechanisms. Advances in experimental medicine and biology, 1990, Volume: 277 Topics: Animals; Bezafibrate; Clofibrate; Combined Modality Therapy; Etanidazole; Female; Hypoxia; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Regional Blood Flow	1990
Experimental intra-arterial administration of SR-2508 in the rabbit V2 carcinoma model. The British journal of radiology, 1989, Volume: 62, Issue:735 Topics: Animals; Etanidazole; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Neoplasms, Experimental; Nitroimidazoles; Rabbits; Radiation-Sensitizing Agents	1989
Accelerated elimination of pimonidazole following microsomal enzyme induction in mice: a possible approach to reduced neurotoxicity of the pimonidazole-etanidazole combination. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Brain; Drug Combinations; Enzyme Induction; Etanidazole; Mice; Mice, Inbred C3H; Microsomes, Liver; Neoplasm Transplantation; Nitroimidazoles; Phenobarbital; Radiation-Sensitizing Agents; Sarcoma, Experimental	1989
Evaluation of nitroimidazole hypoxic cell radiosensitizers in a human tumor cell line high in intracellular glutathione. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Cell Line; Drug Evaluation, Preclinical; Etanidazole; Glutathione; Humans; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989
Pharmacokinetics of etanidazole (SR-2508) in bladder and cervical cancer: evidence of diffusion from urine. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Carcinoma, Squamous Cell; Diffusion; Etanidazole; Female; Humans; Nitroimidazoles; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	1989
Ro 03-8799: preferential relative uptake in human tumor xenografts compared to a murine tumor: comparison with SR-2508. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4 Topics: Animals; Cell Line; Etanidazole; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Transplantation, Heterologous	1989
Effects of nitroimidazoles on neuronal cells in vitro. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Axons; Cell Line; Etanidazole; Intermediate Filaments; Mice; Misonidazole; Neurons; Nitroimidazoles; Radiation-Sensitizing Agents; Rats	1989
Oncogenic transforming potential of nitroimidazole radiosensitizers. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Etanidazole; Mice; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1989
Radiosensitizing and cytotoxic effects of nitroimidazoles in CHO cells expressing elevated levels of glutathione-S-transferase. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Etanidazole; Glutathione Transferase; Melphalan; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1989
The effect of glutathione (GSH) depletion in vivo by buthionine sulfoximine (BSO) on the radiosensitization of SR 2508. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Buthionine Sulfoximine; Etanidazole; Glutathione; Methionine Sulfoximine; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage	1989
Modification of SR 2508 sensitization in hypoxic V79 cells by manipulation of glutathione levels. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Etanidazole; Glutathione; Methionine Sulfoximine; Nitroimidazoles; Oxygen; Pyrrolidonecarboxylic Acid; Radiation-Sensitizing Agents; Thiazoles; Thiazolidines	1989
Addition of misonidazole, etanidazole, or hyperthermia to treatment with fluosol-DA/carbogen/radiation. Journal of the National Cancer Institute, 1989, Jun-21, Volume: 81, Issue:12 Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Drug Combinations; Etanidazole; Fibrosarcoma; Fluorocarbons; Hydroxyethyl Starch Derivatives; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental	1989
Estimation of plasma area under the curve for etanidazole (SR 2508) in toxicity prediction and dose adjustment. International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:1 Topics: Etanidazole; Half-Life; Humans; Monitoring, Physiologic; Nitroimidazoles; Radiation-Sensitizing Agents	1989
Radiosensitization by a new nucleoside analogue: 1-[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl-2-nitroimidazole (RP-170). International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:3 Topics: Animals; Cell Survival; Combined Modality Therapy; Etanidazole; In Vitro Techniques; Mice; Mice, Inbred Strains; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1989
A new, potent 2-nitroimidazole nucleoside hypoxic cell radiosensitizer, RP170. Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:11 Topics: Animals; Cell Survival; Etanidazole; Female; Lethal Dose 50; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1989
Bone marrow toxicity of total-body irradiation combined with radiosensitizers. Radiation research, 1989, Volume: 120, Issue:2 Topics: Animals; Bone Marrow; Dogs; Etanidazole; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Whole-Body Irradiation	1989
Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice. International journal of radiation oncology, biology, physics, 1988, Volume: 14, Issue:2 Topics: Amifostine; Animals; Etanidazole; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasm Metastasis; Neoplasms, Experimental; Nitroimidazoles; Radiation-Protective Agents; Radiation-Sensitizing Agents	1988
Hypoxic cell radiosensitizers in the treatment of high grade gliomas: a new direction using combined Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:3 Topics: Brain Neoplasms; Drug Therapy, Combination; Etanidazole; Glioblastoma; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1988
Evaluation of SR-2508 induced neurotoxicity and myotoxicity in rats using brainstem auditory evoked potentials and the posterior auricular muscle response. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:10 Topics: Animals; Brain Stem; Ear; Etanidazole; Evoked Potentials; Muscles; Neural Conduction; Neurotoxins; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Reflex	1985
A phase I study of the combined hypoxic cell radiosensitizers, Ro 03-8799 and SR 2508: a preliminary report of single-dose toxicity, pharmacokinetics and tumour concentrations. The British journal of radiology, 1986, Volume: 59, Issue:700 Topics: Adenocarcinoma; Drug Combinations; Drug Evaluation; Etanidazole; Humans; Melanoma; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Radiosensitization of hypoxic cells at low doses. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Radiation; Etanidazole; In Vitro Techniques; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1986
Sensitization by SR-2508 plus Ro 03-8799. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Combined Modality Therapy; Drug Combinations; Etanidazole; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Concentrations achieved in human tumors after administration of misonidazole, SR-2508 and Ro 03-8799. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Aged; Etanidazole; Female; Humans; Male; Middle Aged; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1986
A phase I study of the combination of two hypoxic cell radiosensitizers, Ro 03-8799 and SR-2508: toxicity and pharmacokinetics. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Drug Combinations; Drug Evaluation; Etanidazole; Humans; Middle Aged; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1986
A comparison of tumor and normal tissue levels of acidic, basic and neutral 2-nitroimidazole radiosensitizers in mice. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Etanidazole; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Tissue Distribution	1986
Modulation of X ray DNA damage by SR-2508 +/- buthionine sulfoximine. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Buthionine Sulfoximine; Cell Line; Cricetinae; DNA; Drug Synergism; Etanidazole; Glutathione; In Vitro Techniques; Methionine Sulfoximine; Nitroimidazoles; Radiation-Sensitizing Agents	1986
The relationship of SR-2508 sensitizer enhancement ratio to cellular glutathione levels in human tumor cell lines. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Cell Line; Etanidazole; Glutathione; Humans; In Vitro Techniques; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Etanidazole; Glutathione; Humans; Hydrogen Peroxide; In Vitro Techniques; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Pyrazoles; Radiation-Sensitizing Agents	1986
Identification of a reactive glutathione conjugate as a metabolite of SR-2508 in CHO cells. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Animals; Cell Line; Cricetinae; Etanidazole; Glutathione; Imidazoles; In Vitro Techniques; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Variation in sensitizing efficiency for SR 2508 in human cells dependent on glutathione content. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:9 Topics: Cell Line; Cell Survival; Etanidazole; Glutathione; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1986
Ocular penetration, toxicity, and radiosensitization effects of two hypoxic cell radiosensitizers on retinoblastoma. Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:11 Topics: Absorption; Animals; Cell Line; Etanidazole; Eye; Eye Neoplasms; Female; Hypoxia; Nitroimidazoles; Rabbits; Radiation-Sensitizing Agents; Retinoblastoma	1986
The effect of hypoxic cell sensitizers at different irradiation dose rates. Radiation research, 1987, Volume: 109, Issue:3 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Etanidazole; Lung; Misonidazole; Nitroimidazoles; Regression Analysis	1987
SR-2508 plus buthionine sulfoximine or SR-2508 alone: effects on the radiation response and the glutathione content of a human tumor xenograft. Radiation research, 1987, Volume: 110, Issue:1 Topics: Buthionine Sulfoximine; Cell Survival; Cysteine; Etanidazole; Glutathione; Humans; Methionine Sulfoximine; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1987
Gradient high-performance liquid chromatographic method for simultaneous assay of the radiosensitizers etanidazole (SR 2508) and pimonidazole (Ro 03-8799) in biological materials. Journal of chromatography, 1987, Sep-04, Volume: 420, Issue:1 Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Etanidazole; Humans; Nitroimidazoles; Radiation-Sensitizing Agents	1987
Uptake and additivity of the radiosensitizing effects of Ro 03-8799 and SR-2508 in mammalian cells in vitro. The British journal of radiology, 1987, Volume: 60, Issue:720 Topics: Animals; Cell Line; Cricetinae; Drug Synergism; Etanidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1987
[Present status of hypoxic cell sensitizers and PLDR inhibitors]. Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:13 Topics: Animals; Cell Cycle; Cell Line; Etanidazole; Humans; Lung Neoplasms; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage	1987
When can the infusion period be safely ignored in the estimation of pharmacokinetic parameters of drugs in humans? Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:2 Topics: Algorithms; Antineoplastic Agents; Carmustine; Etanidazole; Humans; Infusions, Intravenous; Models, Biological; Nitroimidazoles; Time Factors	1988
Additivity of radiosensitization by the combination of SR 2508 (etanidazole) and Ro 03-8799 (pimonidazole) in a murine tumor system. International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:3 Topics: Animals; Cell Survival; Drug Therapy, Combination; Etanidazole; Female; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1988
Interactions of hyperthermia with hypoxic cell sensitisers. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 109 Topics: Animals; Combined Modality Therapy; Etanidazole; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1988
The multi-dose clinical tolerance and pharmacokinetics of the combined radiosensitizers, Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole). International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:5 Topics: Adult; Aged; Combined Modality Therapy; Drug Therapy, Combination; Etanidazole; Humans; Middle Aged; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1988
Antagonism between radiosensitizing agents. The British journal of radiology, 1988, Volume: 61, Issue:730 Topics: Dose-Response Relationship, Drug; Etanidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1988
[Development of new hypoxic cell radiosensitizer in Japan]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:13 Topics: Animals; Dogs; Drug Evaluation, Preclinical; Etanidazole; Hydroxamic Acids; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1988
Phase I trial of the hypoxic cell radiosensitizer SR-2508: the results of the five to six week drug schedule. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Drug Administration Schedule; Drug Evaluation; Etanidazole; Humans; Nitroimidazoles; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents	1986
Relationship between the neurotoxicity of the hypoxic cell radiosensitizer SR 2508 and the pharmacokinetic profile. Cancer research, 1987, Jan-01, Volume: 47, Issue:1 Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Etanidazole; Humans; Kinetics; Misonidazole; Nitroimidazoles; Peripheral Nervous System Diseases; Radiation-Sensitizing Agents	1987
Selective enhancement of hypoxic cell killing by melphalan via thiol depletion: in vitro studies with hypoxic cell sensitizers and buthionine sulfoximine. Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1 Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Etanidazole; Melphalan; Methionine Sulfoximine; Misonidazole; Nitroimidazoles; Oxygen; Sulfhydryl Compounds	1985
Oxygen dependence of hematoporphyrin derivative-induced photoinactivation of Chinese hamster cells. Cancer research, 1985, Volume: 45, Issue:5 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Etanidazole; Hematoporphyrins; Neoplasms; Nitroimidazoles; Oxygen; Photochemotherapy	1985
The in vitro sensitivity of chronically hypoxic EMT6/SF cells to X-radiation and hypoxic cell radiosensitizers. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:1 Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Etanidazole; Female; Mammary Neoplasms, Experimental; Mice; Misonidazole; Nitroimidazoles; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Rats; Sulfhydryl Compounds; X-Rays	1985
Testing of new hypoxic cell sensitizers in vivo. Radiation research, 1982, Volume: 91, Issue:1 Topics: Animals; Drug Evaluation, Preclinical; Etanidazole; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1982
A comparison of the cytological effects of three hypoxic cell radiosensitizers. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:7 Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Etanidazole; Lung; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Sister Chromatid Exchange	1982
Clinical perspectives for the use of new hypoxic cell sensitizers. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:9 Topics: Animals; Cyclophosphamide; Dogs; Drug Therapy, Combination; Etanidazole; Humans; Melphalan; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Solubility	1982
[Studies in radiosensitizing effects of misonidazole and SR-2508 on experimental animal tumors]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1983, Feb-25, Volume: 43, Issue:2 Topics: Animals; Etanidazole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1983
Sensitization of normal and malignant tissue to cyclophosphamide by nitroimidazoles with different partition coefficients. British journal of cancer, 1984, Volume: 49, Issue:1 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Etanidazole; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Inhibition of X-ray-induced potentially lethal damage (PLD) repair in aerobic plateau-phase Chinese hamster cells by misonidazole. Radiation research, 1984, Volume: 97, Issue:1 Topics: Aerobiosis; Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Etanidazole; Female; Misonidazole; Nitroimidazoles; Ovary; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Time Factors	1984
[Recent advances in hypoxic cell radiosensitizer]. Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:13 Topics: Animals; Cells, Cultured; Etanidazole; Maleates; Mice; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents	1983
Clinical trials of radiosensitizers: what should we expect? International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:3 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Dogs; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Etanidazole; Humans; Kinetics; Lethal Dose 50; Mice; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Factors associated with the preincubation effect of hypoxic cell sensitizers in vitro and their possible implications in chemosensitization. Radiation research, 1984, Volume: 98, Issue:3 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cysteamine; Dose-Response Relationship, Drug; Drug Resistance; Etanidazole; Hydrogen Peroxide; Hyperthermia, Induced; Hypoxia; Melphalan; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Time Factors	1984
Radiosensitizers: a conference preview. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Radiosensitization of hypoxic cells in vivo by SR 2508 at low radiation doses: a preliminary report. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etanidazole; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1984
Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Buthionine Sulfoximine; Combined Modality Therapy; Etanidazole; Glutathione; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1984
Pharmacokinetics and toxicology of continuously infused nitroimidazoles. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Brain; Etanidazole; Female; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents	1984
The oxygen dependence of the reduction of nitroimidazoles in a radiolytic model system. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Acetophenones; Cobalt Radioisotopes; Etanidazole; Gamma Rays; Metronidazole; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Oxygen; Radiation-Sensitizing Agents	1984
The effects of radiosensitizers on intermediary metabolism in vivo. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenocarcinoma; Animals; Dihydroxyacetone Phosphate; Etanidazole; Glycerophosphates; Hydroxybutyrates; Lactates; Liver; Male; Mice; Mice, Inbred Strains; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Pyruvates; Radiation-Sensitizing Agents	1984
A comparison of the ability of some radiosensitizers undergoing clinical trials to act as chemosensitizers. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Etanidazole; Fibrosarcoma; Melphalan; Mice; Mice, Inbred CBA; Misonidazole; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents	1984
The effect of timing on chemosensitization by clinical levels of SR-2508. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Etanidazole; Melphalan; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
Initial report of the phase I trial of the hypoxic cell radiosensitizer SR-2508. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:9 Topics: Drug Evaluation; Etanidazole; Humans; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors	1984
The pharmacokinetics and tumor and neural tissue penetrating properties of SR-2508 and SR-2555 in the dog--hydrophilic radiosensitizers potentially less toxic than misonidazole. Radiation research, 1980, Volume: 84, Issue:3 Topics: Administration, Oral; Animals; Biological Availability; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Etanidazole; Female; Injections, Intravenous; Kinetics; Male; Misonidazole; Neoplasms; Nervous System; Nitroimidazoles; Radiation-Sensitizing Agents; Structure-Activity Relationship	1980
SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use. International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:6 Topics: Animals; Carcinoma; Cell Line; Central Nervous System; Cricetinae; Dogs; Etanidazole; Female; In Vitro Techniques; Lipid Metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; X-Rays	1981
Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers. British journal of cancer, 1982, Volume: 45, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanidazole; Female; Leukocyte Count; Lomustine; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Sarcoma, Experimental	1982
Combined cytokinesis-block micronucleus and chromosomal aberration assay for the evaluation of radiosensitizers at low radiation doses. International journal of radiation oncology, biology, physics, 1994, Dec-01, Volume: 30, Issue:5 Topics: Aerobiosis; Animals; Cell Line; Chromosome Aberrations; Dose-Response Relationship, Radiation; Etanidazole; Female; Mice; Mice, Inbred BALB C; Micronucleus Tests; Mutagenicity Tests; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents	1994
Metabolic studies and neurotoxicity in tumors and brain of mice after hypoxic cell sensitizers. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Adenosine Triphosphate; Animals; Brain; Etanidazole; Glucose; Male; Mice; Mice, Inbred C57BL; Misonidazole; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1994
Comparison of radiosensitizing effect of KU-2285 and SR-2508 at low drug concentrations and doses. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Animals; Carcinoma, Squamous Cell; Cell Survival; Dose-Response Relationship, Drug; Etanidazole; Female; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Nitroimidazoles; Radiation-Sensitizing Agents	1994
Radiosensitizing activity and pharmacokinetics of multiple dose administered KU-2285 in peripheral nerve tissue in mice. International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3 Topics: Animals; Carcinoma, Squamous Cell; Etanidazole; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Misonidazole; Nitroimidazoles; Peripheral Nerves; Radiation-Sensitizing Agents	1994
Relationship between intracellular concentration and radiosensitizing effect of pimonidazole and etanidazole on two human melanoma cell lines. International journal of radiation biology, 1993, Volume: 63, Issue:1 Topics: Etanidazole; Humans; In Vitro Techniques; Melanoma; Nitroimidazoles; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1993
Bioreductive metabolism of AF-2[2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide] combined with 2-nitroimidazoles. Implications for use as hypoxic cell markers. Biochemical pharmacology, 1993, Sep-14, Volume: 46, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line; Drug Interactions; Etanidazole; Furylfuramide; Glucose; Guinea Pigs; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Oxygen Consumption; Rats; Tumor Cells, Cultured	1993
Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts. Cancer research, 1993, Dec-01, Volume: 53, Issue:23 Topics: Animals; Antibodies, Monoclonal; Cell Hypoxia; Etanidazole; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitroimidazoles	1993
In vivo radiosensitization efficacy of KU-2285 and etanidazole at clinically relevant low radiation doses. International journal of radiation oncology, biology, physics, 1993, Dec-01, Volume: 27, Issue:5 Topics: Animals; Cell Division; Cell Line; Chromosome Aberrations; Dose-Response Relationship, Radiation; Etanidazole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Micronucleus Tests; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tumor Cells, Cultured	1993
Relationship between the melanin content of a human melanoma cell line and its radiosensitivity and uptake of pimonidazole. Cancer chemotherapy and pharmacology, 1993, Volume: 31, Issue:4 Topics: Animals; Autoradiography; Cell Line; Etanidazole; Humans; Melanins; Melanoma; Mice; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Tumor Cells, Cultured	1993
Radiosensitization by a new potent nucleoside analog: 1-(1',3',4'-trihydroxy-2'-butoxy)methyl-2-nitroimidazole(RP-343). International journal of radiation oncology, biology, physics, 1993, Jun-15, Volume: 26, Issue:3 Topics: Animals; Cell Hypoxia; Cell Survival; Dogs; Dose-Response Relationship, Drug; Etanidazole; Female; In Vitro Techniques; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Nucleosides; Radiation-Sensitizing Agents	1993
The radiosensitizing effects of hypoxic cell sensitizer on SCCVII tumors in mice evaluated by highly accurate colony formation assay assisted by microcomputer. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1996, Volume: 56, Issue:14 Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Etanidazole; Male; Mice; Mice, Inbred C3H; Microcomputers; Misonidazole; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay	1996
Mitochondrial respiratory chain features after gamma-irradiation. Free radical research, 1997, Volume: 26, Issue:5 Topics: Animals; Cattle; Chromatography, Gas; Chromatography, High Pressure Liquid; Electron Transport; Etanidazole; Gamma Rays; Misonidazole; Mitochondria, Heart; Nitroimidazoles; Spectrophotometry; Succinate Dehydrogenase; Ubiquinone	1997
Substructure in the cell survival response at low radiation dose: effect of different subpopulations. International journal of radiation biology, 1997, Volume: 71, Issue:6 Topics: Animals; Cell Separation; Cell Survival; Cricetinae; Dose-Response Relationship, Radiation; Etanidazole; Humans; Nitroimidazoles; Oxygen; Relative Biological Effectiveness; Tumor Cells, Cultured; X-Rays	1997
Detection of tumour hypoxia: comparison between EF5 adducts and [18F]EF3 uptake on an individual mouse tumour basis. European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:5 Topics: Animals; Cell Hypoxia; Drug Evaluation, Preclinical; Etanidazole; Fibrosarcoma; Fluorescent Antibody Technique; Hydrocarbons, Fluorinated; Male; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Mice; Mice, Inbred C3H; Nitroimidazoles; Organ Specificity; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution	2006
Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches. International journal of radiation oncology, biology, physics, 2007, Volume: 69, Issue:2 Suppl Topics: Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Electrodes; Etanidazole; Head and Neck Neoplasms; Humans; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Neoplasm Proteins; Nitroimidazoles; Osteopontin; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Tirapazamine; Triazines	2007
Importance of antibody concentration in the assessment of cellular hypoxia by flow cytometry: EF5 and pimonidazole. Radiation research, 2008, Volume: 169, Issue:6 Topics: Animals; Area Under Curve; Calibration; Cell Hypoxia; Cell Line, Tumor; Etanidazole; Flow Cytometry; Humans; Hydrocarbons, Fluorinated; Kinetics; Microscopy, Fluorescence; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Rats; Time Factors	2008
Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2 Topics: Adenocarcinoma; Analysis of Variance; Animals; Cell Hypoxia; Colorectal Neoplasms; Etanidazole; Female; Hydrocarbons, Fluorinated; Hyperthermia, Induced; Immunohistochemistry; Mice; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Transplantation, Heterologous	2008
Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. Cancer research, 2008, Oct-15, Volume: 68, Issue:20 Topics: Animals; Antigens, Neoplasm; Arabinofuranosyluracil; Autoradiography; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Etanidazole; Female; Gene Expression; Green Fluorescent Proteins; Herpesvirus 1, Human; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Immunohistochemistry; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Thymidine Kinase; Tissue Distribution; Transplantation, Heterologous	2008
Immunohistochemical detection of changes in tumor hypoxia. International journal of radiation oncology, biology, physics, 2009, Mar-15, Volume: 73, Issue:4 Topics: Animals; Antigens, Neoplasm; Biomarkers, Tumor; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Etanidazole; Female; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mice; Mice, Nude; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	2009
Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model. Cancer biology & therapy, 2009, Volume: 8, Issue:20 Topics: Adenocarcinoma; Animals; Atrasentan; Colonic Neoplasms; Combined Modality Therapy; Etanidazole; Gadolinium DTPA; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Hypoxia; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Nitroimidazoles; Perfusion; Pyrrolidines; Radiation-Sensitizing Agents; Radiotherapy; Treatment Outcome; Xenograft Model Antitumor Assays	2009
Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice. Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:5 Topics: Analysis of Variance; Animals; Aorta; Apolipoprotein B-100; Atherosclerosis; Autoradiography; Disease Models, Animal; Etanidazole; Female; Fluorine Radioisotopes; Genotype; Hydrocarbons, Fluorinated; Hypoxia; Immunohistochemistry; Insulin-Like Growth Factor II; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitroimidazoles; Phenotype; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, LDL; Tissue Distribution	2011
Engineering Biochemistry, 2019, 09-03, Volume: 58, Issue:35 Topics: Antineoplastic Agents; Biosensing Techniques; Cell Hypoxia; Drug Monitoring; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Etanidazole; Genetic Therapy; HCT116 Cells; Humans; Hydrocarbons, Fluorinated; Imidazoles; Molecular Imaging; Neoplasms; Nitroimidazoles; Nitroreductases; Positron-Emission Tomography; Prodrugs; Protein Engineering	2019