Page last updated: 2024-08-17

estrone and methotrexate

estrone has been researched along with methotrexate in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (9.68)	18.7374
1990's	1 (3.23)	18.2507
2000's	12 (38.71)	29.6817
2010's	15 (48.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Sugimoto, Y; Sugiyama, Y; Suzuki, H; Suzuki, M	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Davis, TE; Rose, DP	1
Beattie, CW; Das Gupta, TK; Mehta, RR	1
Benz, C; DeGregorio, M; Drakes, T; Gandara, D; Miller, B; Monroe, S; Wilbur, B	1
Bartosik, DB; Romanoff, EB; Willmott, M	1
Cole, SP; Deeley, RG; Haimeur, A	1
Gan, LS; Liu, N; Miwa, G; Xia, CQ; Yang, D	1
Bow, DA; Perry, JL; Pritchard, JB; Simon, JD	1
Gan, LS; Liu, N; Miwa, GT; Xia, CQ	1
Jang, JE; Jeong, HE; Jung, HJ; Kim, EY; Lee, SJ; Lee, SS; Shin, JG; Yi, JM	1
Hasegawa, M; Kondo, T; Kusuhara, H; Nakazawa, H; Nozaki, Y; Okano, T; Shiroyanagi, Y; Sugiyama, Y	1
Báthori, G; Gedey, S; Glavinas, H; Janáky, T; Krajcsi, P; Méhn, D; Mészáros, P; Molnár, E; Nagy, T; Pál, A; Szente, L; von Richter, O	1
Fricker, G; Miller, DS; Reichel, V	1
Cole, SP; Deeley, RG; DeGorter, MK; Gao, M; Grant, CE	1
Honjo, H; Iwamoto, K; Uwai, Y	1
Dankers, AC; Hoenderop, JG; Masereeuw, R; Mutsaers, HA; Ringens, LH; Russel, FG; van den Heuvel, LP; Wetzels, JF	1
Bikadi, Z; Elmquist, WF; Li, L; Sham, YY	1
Honjo, H; Isaka, T; Iwamoto, K; Ozeki, Y; Uwai, Y	1
Hong, M; Huang, J; Liu, X; Sun, Y; Zhan, K; Zhang, Z	1
Fujita, Y; Katayama, K; Noguchi, K; Sugimoto, Y; Suzuki, T	1
Becquemont, L; Chioukh, R; Fournier, N; Noel-Hudson, MS; Ribes, S; Verstuyft, C	1
Chan, T; Grewal, T; Murray, M; Zheng, J; Zhou, F; Zhu, L	1
Hamada, Y; Ikemura, K; Iwamoto, T; Okuda, M	1

Reviews

2 review(s) available for estrone and methotrexate

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

29 other study(ies) available for estrone and methotrexate

Article	Year
ABCG2 transports sulfated conjugates of steroids and xenobiotics. The Journal of biological chemistry, 2003, Jun-20, Volume: 278, Issue:25 Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Dehydroepiandrosterone Sulfate; Drug Resistance, Neoplasm; Humans; Kinetics; Lymphoma; Mice; Neoplasm Proteins; Recombinant Proteins; Steroids; Sulfuric Acids; Transfection; Tumor Cells, Cultured; Xenobiotics	2003
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Ovarian function in patients receiving adjuvant chemotherapy for breast cancer. Lancet (London, England), 1977, Jun-04, Volume: 1, Issue:8023 Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Dehydroepiandrosterone; Drug Therapy, Combination; Estradiol; Estrone; Female; Fluorouracil; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Lymphatic Metastasis; Melphalan; Menopause; Methotrexate; Middle Aged; Ovary; Vincristine	1977
Endocrine profile in breast cancer patients receiving chemotherapy. Breast cancer research and treatment, 1992, Volume: 20, Issue:2 Topics: Adult; Age Factors; Amenorrhea; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Estradiol; Estrone; Female; Fluorouracil; Hormones; Humans; Luteinizing Hormone; Methotrexate; Middle Aged; Obesity; Prolactin	1992
Chemoendocrine therapy with prolonged estrogen priming in advanced breast cancer: endocrine pharmacokinetics and toxicity. Cancer treatment reports, 1987, Volume: 71, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Estrone; Female; Fluorouracil; Humans; Kinetics; Leucovorin; Methotrexate; Middle Aged; Tamoxifen	1987
The effect of folic acid on superovulation in the immature rat. The Journal of endocrinology, 1968, Volume: 41, Issue:3 Topics: Age Factors; Animals; Chorionic Gonadotropin; Depression, Chemical; Estrone; Female; Folic Acid; Folic Acid Deficiency; Gonadotropins, Equine; Hypophysectomy; Methotrexate; Organ Size; Ovary; Ovulation; Rats; Uterus	1968
Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. The Journal of biological chemistry, 2002, Nov-01, Volume: 277, Issue:44 Topics: Amino Acid Sequence; Biological Transport; Cell Membrane; Estradiol; Estrone; Glutathione; Humans; Leukotriene C4; Methotrexate; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Protein Structure, Secondary; Structure-Activity Relationship; Transfection	2002
Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells. Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:5 Topics: Acridines; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Caco-2 Cells; Estrone; Female; Fluorescent Antibody Technique; Folic Acid Antagonists; Humans; Immunohistochemistry; Kinetics; Methotrexate; Neoplasm Proteins; Tetrahydroisoquinolines	2005
The impact of plasma protein binding on the renal transport of organic anions. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:1 Topics: Animals; Biological Transport, Active; Blood Proteins; Cell Line; Dogs; Estrone; Folic Acid Antagonists; In Vitro Techniques; Kidney; Methotrexate; Ochratoxins; Oocytes; Organic Anion Transporters; Protein Binding; RNA, Complementary; Serum Albumin; Xenopus laevis	2006
Interactions of cyclosporin a with breast cancer resistance protein. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Cell Membrane Permeability; Cyclosporine; Daunorubicin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrone; Female; Humans; Immunosuppressive Agents; Methotrexate; Mutation; Neoplasm Proteins; Transfection	2007
Identification and functional assessment of BCRP polymorphisms in a Korean population. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4 Topics: Adenosine Triphosphatases; Animals; Asian People; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; China; Estrone; Gene Frequency; Genotype; Haplotypes; Humans; In Vitro Techniques; Insecta; Korea; Methotrexate; Microsomes; Neoplasm Proteins; Phenotype; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Vietnam	2007
Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1 Topics: 2,4-Dichlorophenoxyacetic Acid; Biological Transport, Active; Cell Line; Dehydroepiandrosterone Sulfate; Estrone; Humans; In Vitro Techniques; Kidney; Kinetics; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; RNA, Messenger; Transfection	2007
Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Baculoviridae; Benzimidazoles; Biological Transport, Active; Cell Line; Cell Membrane; Cholesterol; Estrone; Glycosylation; Humans; Kinetics; Methotrexate; Neoplasm Proteins; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Pharmaceutical Preparations; Prazosin; Spodoptera; Sulfasalazine; Topotecan	2007
Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:4 Topics: Animals; Biological Transport; Choroid Plexus; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrone; Female; In Vitro Techniques; Kinetics; Leukotriene C4; Male; Meglumine; Methotrexate; Models, Biological; Organic Anion Transporters; p-Aminohippuric Acid; Potassium; Propionates; Protein Kinase C; Quinolines; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Squalus acanthias; Taurocholic Acid; Tetradecanoylphorbol Acetate; Xanthenes	2008
Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3). Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:12 Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line; Cell Membrane; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Estradiol; Estrone; Etoposide; Glutathione; Humans; Kinetics; Leukotriene C4; Methotrexate; Models, Molecular; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Protein Binding; Recombinant Fusion Proteins; Substrate Specificity; Transfection; Vincristine	2008
Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:5 Topics: Animals; Binding, Competitive; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Estrone; Etoricoxib; Humans; Inhibitory Concentration 50; Isoxazoles; Kinetics; Lactones; Methotrexate; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pyrazoles; Pyridines; RNA, Complementary; Sulfonamides; Sulfones; Xenopus laevis	2010
Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations. PloS one, 2011, Apr-04, Volume: 6, Issue:4 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Membrane; Dose-Response Relationship, Drug; Estrone; Gene Expression Regulation; HEK293 Cells; Humans; Kidney Failure, Chronic; Methotrexate; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Substrate Specificity; Toxins, Biological; Uremia	2011
pH-Dependent transport of pemetrexed by breast cancer resistance protein. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:9 Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Transformed; Estrone; Female; Glutamates; Guanine; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Methotrexate; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Proteins; Pemetrexed; Protein Binding; Protein Conformation; Protein Transport; Transport Vesicles; Tumor Microenvironment	2011
Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction. Drug metabolism and pharmacokinetics, 2011, Volume: 26, Issue:5 Topics: Acyclovir; Animals; Caffeic Acids; Chlorogenic Acid; Coffee; Estrone; Food-Drug Interactions; Fruit; Guanine; Humans; Inhibitory Concentration 50; Methotrexate; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Quinic Acid; RNA, Complementary; Vegetables; Xenopus laevis	2011
Identification of multiple binding sites for substrate transport in bovine organic anion transporting polypeptide 1a2. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:3 Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cattle; Estrone; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Organic Anion Transporters; Protein Structure, Secondary; Recombinant Proteins; Rifampin; Sulfobromophthalein; Taurocholic Acid; Transfection	2013
Biochemical interaction of anti-HCV telaprevir with the ABC transporters P-glycoprotein and breast cancer resistance protein. BMC research notes, 2013, Nov-06, Volume: 6 Topics: Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Binding, Competitive; Biological Transport; Cell Membrane; Estrone; Humans; Iodine Radioisotopes; K562 Cells; Kinetics; Methotrexate; Neoplasm Proteins; Oligopeptides; Protein Binding; Subcellular Fractions; Tritium; Vincristine	2013
Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:12 Topics: Biological Transport; Cell Line; Drug Interactions; Estrone; HEK293 Cells; Humans; Kidney Tubules, Proximal; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Proton Pump Inhibitors	2014
Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control. Molecular pharmaceutics, 2015, Jan-05, Volume: 12, Issue:1 Topics: Base Sequence; Biotinylation; Cell Line; Estrone; HEK293 Cells; Humans; Immunoblotting; Kinetics; Methotrexate; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters; Pharmacogenetics; Protein Binding; Protein Structure, Tertiary; Protein Transport	2015
Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers. Pharmacology, 2018, Volume: 101, Issue:3-4 Topics: Drug Interactions; Estrone; HEK293 Cells; Humans; Kidney; Lansoprazole; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pemetrexed; Probenecid; Proton Pump Inhibitors; Stereoisomerism	2018