Page last updated: 2024-08-17

estrone and metformin

estrone has been researched along with metformin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's10 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bellows, AB; Eagleson, CA; Gingrich, MB; Hu, K; Marshall, JC1
Bahtiyar, G; Sacerdote, AS; Weiss, K1
Carlsen, SM; Vanky, E1
Li, L; Nouraldeen, A; Wilson, AG1
Fukuhara, A; Ishiguro, N; Kusuhara, H; Lechner, C; Nishiyama, K; Ohtsu, N; Shimizu, H; Takatani, M; Washio, I; Yamamura, N1
Agturk, G; Dogan, H; Dokuyucu, R; Karateke, A; Ozgur, T; Tas, ZA; Tumer, C; Tutuk, O1

Reviews

2 review(s) available for estrone and metformin

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for estrone and metformin

ArticleYear
Obese patients with polycystic ovary syndrome: evidence that metformin does not restore sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by ovarian steroids.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adult; Androstenedione; Estrone; Feedback, Physiological; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Luteinizing Hormone; Metformin; Obesity; Polycystic Ovary Syndrome; Pulsatile Flow; Testosterone

2003
Metformin influence on hormone levels at birth, in PCOS mothers and their newborns.
    Human reproduction (Oxford, England), 2010, Volume: 25, Issue:3

    Topics: Adult; Androgens; Androstane-3,17-diol; Estradiol; Estrone; Female; Fetal Blood; Humans; Hypoglycemic Agents; Infant, Newborn; Male; Metformin; Polycystic Ovary Syndrome; Pregnancy; Sex Hormone-Binding Globulin; Testosterone

2010

Other Studies

8 other study(ies) available for estrone and metformin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Novel endocrine disrupter effects of classic and atypical antipsychotic agents and divalproex: induction of adrenal hyperandrogenism, reversible with metformin or rosiglitazone.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2007, Volume: 13, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adult; Aged; Antipsychotic Agents; Cortodoxone; Dehydroepiandrosterone; Endocrine Disruptors; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin Resistance; Luteinizing Hormone; Male; Metformin; Middle Aged; Radioimmunoassay; Rosiglitazone; Testosterone; Thiazolidinediones; Valproic Acid

2007
Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:3

    Topics: Animals; Atorvastatin; Biological Assay; Biological Transport; Blood Proteins; Cells, Cultured; Cryopreservation; Estrone; Female; Hepatocytes; Heptanoic Acids; High-Throughput Screening Assays; Humans; Kinetics; Liver; Male; Metformin; Organic Anion Transporters; Pravastatin; Pyrroles; Radioactivity; Reproducibility of Results; Species Specificity; Time Factors

2013
Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:8

    Topics: 1-Methyl-4-phenylpyridinium; Biological Transport; Buffers; Dose-Response Relationship, Drug; Drug Interactions; Estrone; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Modulators; Metformin; Organic Cation Transport Proteins; Rhodamine 123; Risk Assessment; Thiamine; Transfection

2016
Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2018, Volume: 27, Issue:6

    Topics: Analysis of Variance; Animals; Blood Glucose; Cholesterol; Disease Models, Animal; Estrone; Expectorants; Female; Hypoglycemic Agents; Insulin Resistance; Metformin; Ovary; Oxidative Stress; Polycystic Ovary Syndrome; Random Allocation; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Treatment Outcome; Uterus

2018