estrone has been researched along with letrozole in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 10 (31.25) | 29.6817 |
| 2010's | 9 (28.13) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Demers, LM | 1 |
| Bhatnagar, AS; Dickes, I; Monnet, G; Mueller, P; Trunet, PF; White, G | 1 |
| Ahern, J; Dowsett, M; Iveson, TJ; Smith, IE; Smithers, DA; Trunet, PF | 2 |
| Brady, C; Demers, LM; Grossberg, H; Harvey, HA; Kambic, KB; Lipton, A; Santen, RJ | 1 |
| Choate, JV; Resko, JA | 1 |
| Bisagni, G; Cocconi, G; Fraschini, F; Pfister, C; Scaglione, F; Trunet, PF | 1 |
| Dowsett, M; Jacobs, S; Johnston, SR; Jones, A; Smith, IE; Trunet, P | 1 |
| Bonneterre, J; Feutrie, ML | 1 |
| Heshmati, HM; Khosla, S; Melton, LJ; O'Fallon, WM; Riggs, BL; Robins, SP | 1 |
| Anker, G; Dowsett, M; Geisler, J; Haynes, B; Lønning, PE | 1 |
| Dixon, JM; Miller, WR | 1 |
| Adachi, I; Ikeda, T; Ohashi, Y; Sasaki, Y; Suwa, T; Tabei, T; Takatsuka, Y; Toi, M; Tominaga, T | 1 |
| Bhatnagar, AS; Dixon, JM; Dowsett, M; Haynes, BP; Miller, WR | 1 |
| Hori, H; Kagawa, N; Waterman, MR; Yoshioka, S | 1 |
| Aberdeen, GW; Albrecht, ED; Pepe, GJ | 1 |
| Lykkesfeldt, AE; Sonne-Hansen, K | 1 |
| A'Hern, RP; Cameron, DA; Dixon, JM; Dowsett, M; Folkerd, E; Macaskill, EJ; McHugh, M; Murray, J; Renshaw, L; Young, O | 1 |
| Aas, T; Duong, NK; Ekse, D; Evans, DB; Geisler, J; Helle, H; Lønning, PE; Nordbø, Y | 1 |
| Chen, S; Hong, Y; Rashid, R | 1 |
| Horie, T; Shitara, Y; Tanii, H | 1 |
| A'Hern, RP; Dixon, JM; Dowsett, M; Folkerd, EJ; Renshaw, L | 1 |
| Bighin, C; Bisagni, G; Bruzzi, P; Cavazzini, G; Clavarezza, M; Del Mastro, L; Garrone, O; Lastraioli, S; Lunardi, G; Mansutti, M; Marroni, P; Notaro, R; Piccioli, P; Ponzone, R; Porpiglia, M; Puglisi, F; Serra, M | 1 |
| Bighin, C; Bisagni, G; Cirillo, M; Del Mastro, L; Giraudi, S; Gnoni, R; Levaggi, A; Lunardi, G; Mansutti, M; Marenco, D; Picardo, E; Piccioli, P; Ponzone, R; Porpiglia, M; Puglisi, F; Sini, V; Stridi, G; Turazza, M | 1 |
| Dowsett, M; Haynes, BP; Lønning, PE | 1 |
| Berger, T; Conley, A; Kucera, H; Puschner, B | 1 |
| Almås, B; Bertelsen, BE; Geisler, J; Hagland, M; Helland, T; Lende, TH; Lønning, PE; Mellgren, G; Sagen, JV; Søiland, H; Viste, K | 1 |
| Coleman, RL; Copeland, LJ; Filiaci, VL; Finkelstein, KA; Fleury, AC; Holman, LL; Miller, DS; Moroney, JW; Muller, CY; Slomovitz, BM; Taub, MC; Walker, JL | 1 |
| Babbitt, C; Edwards, M; Lacreuse, A; Lam, S; Pereira, M; Ranjan, R | 1 |
| Blomqvist, C; Faltinová, M; Haanpää, M; Hämäläinen, E; Lyytinen, H; Mattson, J; Tiitinen, A; Vehmanen, L | 1 |
3 review(s) available for estrone and letrozole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Aromatase inhibitors].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles | 1999 |
The pharmacology of letrozole.
Topics: Adrenocorticotropic Hormone; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estradiol; Estrone; Humans; Letrozole; Nitriles; Triazoles | 2003 |
15 trial(s) available for estrone and letrozole
| Article | Year |
|---|---|
Effects of Fadrozole (CGS 16949A) and Letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients.
Topics: Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens; Estrone; Fadrozole; Female; Humans; Letrozole; Middle Aged; Nitriles; Radioimmunoassay; Triazoles | 1994 |
Open dose-finding study of a new potent and selective nonsteroidal aromatase inhibitor, CGS 20 267, in healthy male subjects.
Topics: Administration, Oral; Adult; Aldosterone; Aromatase Inhibitors; Blood Pressure; Dose-Response Relationship, Drug; Estradiol; Estrone; Follicle Stimulating Hormone; Headache; Humans; Hydrocortisone; Letrozole; Luteinizing Hormone; Male; Middle Aged; Nitriles; Testosterone; Triazoles | 1993 |
Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in healthy postmenopausal women.
Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Aged; Aldosterone; Androstenedione; Aromatase Inhibitors; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Hydroxyprogesterones; Letrozole; Luteinizing Hormone; Male; Menopause; Middle Aged; Nitriles; Random Allocation; Testosterone; Thyrotropin; Time Factors; Triazoles | 1993 |
Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer.
Topics: Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Humans; Letrozole; Microsomes; Middle Aged; Nitriles; Triazoles | 1993 |
The efficacy of CGS 20267 in suppressing estrogen biosynthesis in patients with advanced stage breast cancer.
Topics: Aldosterone; Anti-Inflammatory Agents, Non-Steroidal; Aromatase Inhibitors; Breast Neoplasms; Cosyntropin; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Letrozole; Neoplasm Staging; Nitriles; Potassium; Sodium; Time Factors; Triazoles | 1993 |
Letrozole, a new oral non-steroidal aromastase inhibitor in treating postmenopausal patients with advanced breast cancer. A pilot study.
Topics: Adult; Aged; Aldosterone; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Hydrocortisone; Letrozole; Middle Aged; Nitriles; Pilot Projects; Triazoles | 1996 |
In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with breast cancer.
Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrone; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Nitriles; Postmenopause; Triazoles | 1995 |
Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women.
Topics: Aged; Aromatase Inhibitors; Bone Remodeling; Bone Resorption; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Menopause; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Prospective Studies; Triazoles | 2002 |
Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study.
Topics: Aged; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Chromatography, High Pressure Liquid; Cross-Over Studies; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2002 |
Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer.
Topics: Administration, Oral; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrone; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Safety; Survival Rate; Triazoles | 2003 |
Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Estradiol; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2008 |
Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women.
Topics: Aged; Antineoplastic Agents; Aromatase Inhibitors; Aryl Hydrocarbon Hydroxylases; Asian People; Bilirubin; Body Weight; Creatinine; Cytochrome P-450 CYP2A6; Estradiol; Estrone; Female; Genotype; Humans; Letrozole; Nitriles; Polymorphism, Genetic; Postmenopause; Triazoles | 2011 |
A randomized phase II trial of everolimus and letrozole or hormonal therapy in women with advanced, persistent or recurrent endometrial carcinoma: A GOG Foundation study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Endometrial Neoplasms; Estradiol; Estriol; Estrone; Everolimus; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases | 2022 |
Effects of letrozole on serum estradiol and estrone in postmenopausal breast cancer patients and tolerability of treatment: a prospective trial using a highly sensitive LC-MS/MS (liquid chromatography-tandem mass spectrometry) method for estrogen measurem
Topics: Breast Neoplasms; Chromatography, Liquid; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Postmenopause; Prospective Studies; Quality of Life; Tandem Mass Spectrometry | 2023 |
14 other study(ies) available for estrone and letrozole
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Paradoxical effect of an aromatase inhibitor, CGS 20267, on aromatase activity in guinea pig brain.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Brain; Enzyme Inhibitors; Estradiol; Estrone; Guinea Pigs; Kinetics; Letrozole; Male; Microsomes; Nitriles; Orchiectomy; Testosterone; Triazoles | 1996 |
Local endocrine effects of aromatase inhibitors within the breast.
Topics: Anastrozole; Androstadienes; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Cells, Cultured; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogens; Estrone; Female; Fibroblasts; Humans; In Vitro Techniques; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2001 |
Characterization of stable human aromatase expressed in E. coli.
Topics: Amino Acid Sequence; Androstenedione; Arginine; Aromatase; Aromatase Inhibitors; Cell Membrane; Chaperonin 10; Chaperonin 60; Chloramphenicol; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Stability; Escherichia coli; Estradiol; Estrone; Fadrozole; Gene Expression; Humans; Letrozole; Molecular Sequence Data; Nitriles; Polymorphism, Genetic; Protein Structure, Secondary; Protein Synthesis Inhibitors; Recombinant Proteins; Solubility; Testosterone; Triazoles | 2004 |
Estrogen elicits cortical zone-specific effects on development of the primate fetal adrenal gland.
Topics: Adrenal Cortex; Animals; Dehydroepiandrosterone Sulfate; Estradiol; Estrogens; Estrone; Female; Fetal Development; Letrozole; Nitriles; Organ Size; Papio; Pituitary Gland; Pro-Opiomelanocortin; RNA, Messenger; Triazoles | 2005 |
Endogenous aromatization of testosterone results in growth stimulation of the human MCF-7 breast cancer cell line.
Topics: Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Culture Media; Dose-Response Relationship, Drug; Estrogen Antagonists; Estrogens; Estrone; Female; Humans; Letrozole; Nitriles; Receptors, Estrogen; Testosterone; Triazoles; Tumor Cells, Cultured | 2005 |
Binding features of steroidal and nonsteroidal inhibitors.
Topics: Amino Acids; Androgens; Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Catalytic Domain; Estrogens; Estrone; Female; Humans; Letrozole; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Neoplasms, Hormone-Dependent; Nitriles; Protein Conformation; Structure-Activity Relationship; Triazoles | 2011 |
Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles | 2012 |
Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrone; Female; Genetic Association Studies; Genotype; Humans; Letrozole; Middle Aged; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Prospective Studies; Triazoles | 2013 |
Body mass index and circulating oestrone sulphate in women treated with adjuvant letrozole.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Triazoles | 2014 |
Relationship of body mass index with aromatisation and plasma and tissue oestrogen levels in postmenopausal breast cancer patients treated with aromatase inhibitors.
Topics: Aged; Anastrozole; Androgens; Aromatase; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Outcome Assessment, Health Care; Postmenopause; Triazoles | 2014 |
Tissue steroid levels in response to reduced testicular estrogen synthesis in the male pig, Sus scrofa.
Topics: Animals; Aromatase Inhibitors; Estradiol; Estrogens; Estrone; Letrozole; Liver; Male; Prostate; Sus scrofa; Testis | 2019 |
Simultaneous Quantification of Aromatase Inhibitors and Estrogens in Postmenopausal Breast Cancer Patients.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Nitriles; Postmenopause; Tandem Mass Spectrometry | 2022 |
Letrozole treatment alters hippocampal gene expression in common marmosets (Callithrix jacchus).
Topics: Animals; Aromatase Inhibitors; Callithrix; Estrone; Female; Gene Expression; Hippocampus; Letrozole; Male; Nitriles; Triazoles | 2023 |