Page last updated: 2024-08-17

estrone and ketoconazole

estrone has been researched along with ketoconazole in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's5 (27.78)18.2507
2000's3 (16.67)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adelmann, B; Engelhardt, D; Weber, MM; Will, A1
Capelli, M; Dal Prato, L; Fabbri, R; Flamigni, C; Magrini, O; Mantovani, B; Venturoli, S1
Ayub, M; Levell, MJ1
Cantwell, BM; Dowsett, M; Harris, AL1
Adamski, J; Hohls, E; Jungblut, PW1
Bhatnagar, AS; King, EJ; Purba, HS; Richert, P1
Kikuchi, A; Maeda, T; Nozawa, T; Tamai, I; Wakasawa, T1
Blode, H; Kunz, M; Mellinger, U; Parke, S; Rohde, B; Zeun, S; Zimmermann, T1
Liu, J; Lu, G; Yan, Z; Ye, Q1
Baj, F; Baravalle, R; Ciaramella, A; Di Nardo, G; Gilardi, G1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Reviews

1 review(s) available for estrone and ketoconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for estrone and ketoconazole

ArticleYear
Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women.
    Contraception, 2012, Volume: 86, Issue:4

    Topics: Aged; Anti-Infective Agents; Biotransformation; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Combinations; Drug Interactions; Enzyme Induction; Erythromycin; Estradiol; Estrogen Replacement Therapy; Estrone; Female; Humans; Ketoconazole; Middle Aged; Nandrolone; Postmenopause; Rifampin

2012

Other Studies

16 other study(ies) available for estrone and ketoconazole

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effect of ketoconazole on human ovarian C17,20-desmolase and aromatase.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androstenedione; Aromatase; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Female; Granulosa Cells; Humans; Hydroxyprogesterones; Ketoconazole; Ovary; Steroid 17-alpha-Hydroxylase

1991
Ketoconazole therapy for women with acne and/or hirsutism.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:2

    Topics: Acne Vulgaris; Adrenocorticotropic Hormone; Adult; Androgens; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hair; Hirsutism; Humans; Hydrocortisone; Ketoconazole; Luteinizing Hormone

1990
The inhibition of human prostatic aromatase activity by imidazole drugs including ketoconazole and 4-hydroxyandrostenedione.
    Biochemical pharmacology, 1990, Oct-01, Volume: 40, Issue:7

    Topics: Androstenedione; Aromatase Inhibitors; Estradiol; Estrone; Humans; Imidazoles; Ketoconazole; Male; Prostate; Structure-Activity Relationship

1990
High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer.
    British journal of cancer, 1988, Volume: 58, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Menopause; Middle Aged; Sex Hormone-Binding Globulin; Testosterone

1988
Characterization of estrone hydroxylase activities in porcine endometrial cells.
    Experimental and clinical endocrinology, 1994, Volume: 102, Issue:5

    Topics: Alcohol Oxidoreductases; Animals; Cell Fractionation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endometrium; Estrone; Female; Hydrogen-Ion Concentration; Hydroxylation; Ketoconazole; Microsomes; Substrate Specificity; Swine

1994
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:2-3

    Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity

1994
Transporter-mediated intestinal absorption of fexofenadine in rats.
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:4

    Topics: Animals; Anti-Allergic Agents; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane Permeability; Dose-Response Relationship, Drug; Estrone; Intestinal Absorption; Ketoconazole; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; Terfenadine; Xenopus

2006
Modulation of 17β-estradiol induced estrogenic responses in male goldfish (Carassius auratus) by benzo[a]pyrene and ketoconazole.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:9

    Topics: Animals; Benzo(a)pyrene; Biotransformation; Cytochrome P-450 CYP1A1; Estradiol; Estrone; Goldfish; Ketoconazole; Liver; Male; Vitellogenins; Water Pollutants, Chemical

2016
Identification of endocrine disrupting chemicals acting on human aromatase.
    Biochimica et biophysica acta. Proteins and proteomics, 2018, Volume: 1866, Issue:1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Biological Assay; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estrone; Gene Expression; Humans; Ketoconazole; Ligands; NADP; Nicotine; Nitriles; Phenols; Protein Binding; Recombinant Proteins; Resveratrol; Sildenafil Citrate; Small Molecule Libraries; Stilbenes; Triazoles

2018
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016