Page last updated: 2024-08-17

estrone and indole-3-carbinol

estrone has been researched along with indole-3-carbinol in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's8 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bradlow, HL; Michnovicz, JJ1
Bradlow, HL; Levy, I; Michnovicz, J; Murtezani, S; Osborne, MP; Sepkovic, DW1
Michnovicz, JJ1
Bradlow, HL; Ganguly, S; Garbers, SV; Garte, SJ; Osborne, MP; Sepkovic, DW; Taioli, E; Trachman, J1
Bell, MC; Bradlow, HL; Crowley-Nowick, P; Howell, P; Mathis, JM; Mayeaux, EJ; Schmidt-Grimminger, D; Sepkovic, DW; Tucker, A; Turbat-Herrera, EA1
Gaston, K; Taylor, A; Webster, K1
Malejka-Giganti, D; Prigge, WF; Reichert, MA; Ritter, CL1
Beppu, M; Ebihara, K; Izumi, T; Kishida, T; Nashiki, K1
Chen, T; Gulin, J; Klug, T; Lahita, R; McAlindon, TE; Nuite, M1
Ashok, BT; Bradlow, HL; Chen, Y; Liu, X; Mittelman, A; Tiwari, RK1
Bliss, RL; Horn, TL; Malejka-Giganti, D; Reichert, MA1
Laciński, M; Ociepa-Zawal, M; Rubiś, B; Trzeciak, WH1

Trials

4 trial(s) available for estrone and indole-3-carbinol

ArticleYear
Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1998, Volume: 22, Issue:3

    Topics: Administration, Oral; Adult; Antioxidants; Cohort Studies; Estradiol; Estriol; Estrogen Antagonists; Female; Humans; Hydroxyestrones; Hydroxylation; Indoles; Middle Aged; Obesity; Premenopause

1998
Role of estradiol metabolism and CYP1A1 polymorphisms in breast cancer risk.
    Cancer detection and prevention, 1999, Volume: 23, Issue:3

    Topics: Adult; Black People; Breast Neoplasms; Case-Control Studies; Cytochrome P-450 CYP1A1; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Genotype; Humans; Hydroxyestrones; Indoles; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; RNA, Messenger; White People

1999
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.
    Gynecologic oncology, 2000, Volume: 78, Issue:2

    Topics: Administration, Oral; Anticarcinogenic Agents; DNA, Viral; Dose-Response Relationship, Drug; Female; Humans; Hydroxyestrones; Indoles; Papillomaviridae; Papillomavirus Infections; Placebos; Polymerase Chain Reaction; Precancerous Conditions; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2000
Indole-3-carbinol in women with SLE: effect on estrogen metabolism and disease activity.
    Lupus, 2001, Volume: 10, Issue:11

    Topics: Adult; Estrogen Antagonists; Estrogens; Female; Humans; Hydroxyestrones; Indoles; Lupus Erythematosus, Systemic; Middle Aged; Severity of Illness Index

2001

Other Studies

8 other study(ies) available for estrone and indole-3-carbinol

ArticleYear
Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol.
    Nutrition and cancer, 1991, Volume: 16, Issue:1

    Topics: Adult; Antioxidants; Body Mass Index; Body Water; Estradiol; Estriol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Indoles; Male; Tritium

1991
Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or beta-naphthaflavone: a comparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods.
    Steroids, 1994, Volume: 59, Issue:5

    Topics: Animals; Ascorbic Acid; Benzoflavones; beta-Naphthoflavone; Estradiol; Estrogens, Catechol; Female; Gas Chromatography-Mass Spectrometry; Hydroxyestrones; Hydroxylation; Indoles; Microsomes, Liver; Radiometry; Rats; Rats, Sprague-Dawley

1994
Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins.
    The Journal of general virology, 2001, Volume: 82, Issue:Pt 1

    Topics: Apoptosis; DNA-Binding Proteins; Dose-Response Relationship, Drug; Estrogens; HeLa Cells; Humans; Hydroxyestrones; Indoles; Mifepristone; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Progesterone; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

2001
Oxidations of 17beta-estradiol and estrone and their interconversions catalyzed by liver, mammary gland and mammary tumor after acute and chronic treatment of rats with indole-3-carbinol or beta-naphthoflavone.
    Canadian journal of physiology and pharmacology, 2001, Volume: 79, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrone; Female; Indoles; Isoenzymes; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution

2001
Effect of dietary soy isoflavone aglycones on the urinary 16alpha-to-2-hydroxyestrone ratio in C3H/HeJ mice.
    Nutrition and cancer, 2000, Volume: 38, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Biomarkers; Cytochrome P-450 Enzyme System; Female; Genistein; Glycine max; Hydroxyestrones; Indoles; Isoflavones; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Microsomes, Liver; Organ Size; Plant Extracts

2000
Abrogation of estrogen-mediated cellular and biochemical effects by indole-3-carbinol.
    Nutrition and cancer, 2001, Volume: 41, Issue:1-2

    Topics: Brassicaceae; Breast Neoplasms; Cell Division; Cytochrome P-450 CYP1A1; Estradiol; Estrogen Antagonists; Estrogens; Estrone; Humans; Hydroxylation; Indoles; Phosphorylation; Receptors, Estrogen; Signal Transduction; Tumor Cells, Cultured; Vegetables

2001
Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol.
    Biochemical pharmacology, 2002, Aug-01, Volume: 64, Issue:3

    Topics: Animals; Breast; Cytochrome P-450 Enzyme System; Estradiol; Estrogen Antagonists; Estrogens; Estrone; Female; Gene Expression; Indoles; Liver; Models, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger

2002
The effect of indole-3-carbinol on the expression of CYP1A1, CYP1B1 and AhR genes and proliferation of MCF-7 cells.
    Acta biochimica Polonica, 2007, Volume: 54, Issue:1

    Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Estradiol; Estrogen Receptor Modulators; Estrone; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Indoles; Receptors, Aryl Hydrocarbon

2007