Page last updated: 2024-08-17

estrone and formestane

estrone has been researched along with formestane in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (41.67)	18.7374
1990's	9 (37.50)	18.2507
2000's	3 (12.50)	29.6817
2010's	2 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Bellavance, E; Luu-The, V; Poirier, D	1
Barmade, MA; Murumkar, PR; Tamboli, RS; Yadav, MR	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Dowsett, M; Jacobs, S; Jones, AL; Lonning, PE; MacNeill, F; Powles, TJ	1
Aherne, GW; Chakraborty, J; Ghilchik, MW; Patel, S; Reed, MJ	1
Ayub, M; Levell, MJ	1
Coldham, NG; Ghilchik, MW; James, VH; Lai, LC; Owen, AM; Purohit, A; Reed, MJ; Shaikh, NA; Singh, A	1
Bartsch, W; Klein, H; Stürenburg, HJ; Voigt, KD	1
Coldham, NG; Ghilchik, MW; James, VH; Lai, LC; Owen, AM; Reed, MJ; Shaikh, NA	1
Oakey, RE; Purohit, A	1
Coombes, RC; Cunningham, DC; Dehennin, L; Dowsett, M; Evans, S; Hedley, A; Stein, RC	1
Brodie, AM; Coombes, RC; Dowsett, M; Gazet, JC; Goss, PE; Hutchison, G; Powles, TJ	1
Longcope, C; Mordes, JP; Orczyk, GP	1
Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C	1
Gelly, C; Pasqualini, JR; Sumida, C	1
Feil, PD; Santen, RJ; Santner, SJ; Tilson-Mallett, N	1
Abul-Hajj, YJ	1
Reed, MJ	1
Bhatnagar, AS; King, EJ; Purba, HS; Richert, P	1
Ekse, D; Lønning, PE	1
Amichetti, M; Attili, A; Bajetta, E; Barni, S; Bichisao, E; Bolelli, GF; Bombardieri, E; Buzzoni, R; Comella, G; D'Aprile, M; Ferrari, L; Jirillo, A; Martinetti, A; Noberasco, C; Schieppati, G; Zilembo, N	1
Bonneterre, J; Feutrie, ML	1

Reviews

4 review(s) available for estrone and formestane

Article	Year
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer. European journal of medicinal chemistry, 2015, Nov-13, Volume: 105 Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Molecular Structure	2015
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways. Annals of the New York Academy of Sciences, 1986, Volume: 464 Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone	1986
The role of aromatase in breast tumors. Breast cancer research and treatment, 1994, Volume: 30, Issue:1 Topics: Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; DNA Polymerase II; Estrogens; Estrone; Female; Humans; Prognosis; Receptors, Progesterone; Tumor Cells, Cultured	1994
[Aromatase inhibitors]. Bulletin du cancer, 1999, Volume: 86, Issue:10 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles	1999

Trials

2 trial(s) available for estrone and formestane

Article	Year
Dose-related endocrine effects and pharmacokinetics of oral and intramuscular 4-hydroxyandrostenedione in postmenopausal breast cancer patients. Cancer research, 1989, Mar-01, Volume: 49, Issue:5 Topics: Administration, Oral; Androstenedione; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Half-Life; Humans; Injections, Intramuscular; Menopause; Sex Hormone-Binding Globulin	1989
A multicentre, randomized, pharmacokinetic, endocrine and clinical study to evaluate formestane in breast cancer patients at first relapse: endocrine and clinical results. The Italian Trials in Medical Oncology (I.T.M.O.) group. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Injections, Intramuscular; Middle Aged; Postmenopause; Survival Analysis; Treatment Outcome	1997

Article

Year

Cancer research, 1989, Mar-01, Volume: 49, Issue:5

Topics: Administration, Oral; Androstenedione; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Half-Life; Humans; Injections, Intramuscular; Menopause; Sex Hormone-Binding Globulin

1989

A multicentre, randomized, pharmacokinetic, endocrine and clinical study to evaluate formestane in breast cancer patients at first relapse: endocrine and clinical results. The Italian Trials in Medical Oncology (I.T.M.O.) group.

Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7

Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Injections, Intramuscular; Middle Aged; Postmenopause; Survival Analysis; Treatment Outcome

1997

Other Studies

18 other study(ies) available for estrone and formestane

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity	2009
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
The influence of intramuscular 4-hydroxyandrostenedione on peripheral aromatisation in breast cancer patients. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:10 Topics: Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estriol; Estrone; Female; Humans; Injections, Intramuscular; Middle Aged	1992
Concentrations of oestrone and 4-hydroxyandrostenedione in malignant and normal breast tissues. International journal of cancer, 1991, Oct-21, Volume: 49, Issue:4 Topics: Aged; Androstenedione; Aromatase Inhibitors; Breast; Breast Neoplasms; DNA Polymerase II; Estrone; Female; Humans; Neoplasm Staging	1991
The inhibition of human prostatic aromatase activity by imidazole drugs including ketoconazole and 4-hydroxyandrostenedione. Biochemical pharmacology, 1990, Oct-01, Volume: 40, Issue:7 Topics: Androstenedione; Aromatase Inhibitors; Estradiol; Estrone; Humans; Imidazoles; Ketoconazole; Male; Prostate; Structure-Activity Relationship	1990
Effect of treatment with 4-hydroxyandrostenedione on the peripheral conversion of androstenedione to estrone and in vitro tumor aromatase activity in postmenopausal women with breast cancer. Cancer research, 1990, Jan-01, Volume: 50, Issue:1 Topics: Aged; Androstenedione; Antineoplastic Agents; Aromatase; Breast Neoplasms; DNA Polymerase II; Estrone; Female; Humans; Kinetics; Metabolic Clearance Rate	1990
Metabolism of androgens in human benign prostatic hyperplasia: aromatase and its inhibition. Journal of steroid biochemistry, 1987, Volume: 27, Issue:1-3 Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Estrone; Humans; Male; Microsomes; Placenta; Prostate; Prostatic Hyperplasia; Testolactone	1987
In situ oestrone synthesis in normal breast and breast tumour tissues: effect of treatment with 4-hydroxyandrostenedione. International journal of cancer, 1989, Aug-15, Volume: 44, Issue:2 Topics: Aged; Androstenedione; Aromatase; Breast; Breast Neoplasms; DNA Polymerase II; Estrone; Female; Humans; Middle Aged	1989
Evidence for separate sites for aromatisation of androstenedione and 16 alpha-hydroxyandrostenedione in human placental microsomes. Journal of steroid biochemistry, 1989, Volume: 33, Issue:3 Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; In Vitro Techniques; Kinetics; Microsomes; Placenta; Pregnancy; Radioimmunoassay	1989
Treatment of advanced postmenopausal breast cancer with an aromatase inhibitor, 4-hydroxyandrostenedione: phase II report. Cancer research, 1986, Volume: 46, Issue:9 Topics: Adult; Aged; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Drug Evaluation; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Sex Hormone-Binding Globulin	1986
Aromatase activity in a rat Leydig cell tumor. Endocrinology, 1987, Volume: 120, Issue:4 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Bucladesine; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Estrone; Leydig Cell Tumor; Male; Neoplasm Transplantation; Rats; Rats, Inbred WF; Testicular Neoplasms; Testosterone; Tetradecanoylphorbol Acetate; Water	1987
4-Hydroxyandrostenedione is not an aromatase inhibitor in the neonatal guinea pig. Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6 Topics: Androstenedione; Animals; Animals, Newborn; Aromatase Inhibitors; Estradiol; Estrone; Female; Guinea Pigs; Organ Culture Techniques; Organ Size; Receptors, Estrogen; Receptors, Progesterone; Uterus	1987
Biological significance of aromatase activity in human breast tumors. The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:6 Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrone; Female; Humans; Oxidoreductases; Receptors, Estrogen; Receptors, Progesterone; Testolactone	1983
Inhibition of androgen aromatization in human breast cancer. Journal of steroid biochemistry, 1980, Volume: 13, Issue:12 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estradiol; Estrone; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy	1980
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver. The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:2-3 Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity	1994
A sensitive assay for measurement of plasma estrone sulphate in patients on treatment with aromatase inhibitors. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrone; Female; Humans; Hydrolysis; Menopause; Radioimmunoassay; Sensitivity and Specificity	1995