Page last updated: 2024-08-17

estrone and fadrozole

estrone has been researched along with fadrozole in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (75.00)18.2507
2000's4 (20.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aupetit, B; Bhatnagar, AS; Ezzet, F; Girard, F; Menard, J; Mueller, P; Trunet, PF; Zognbi, F1
Demers, LM; Garber, JE; Hanagan, J; Harvey, H; Henderson, IC; Lipton, A; Lynch, J; Mulagha, M; Navari, RM; Santen, RJ1
Dowsett, M; Haynes, B; Jacobs, S; Jones, A; Lønning, PE; Powles, T1
Horiuchi, R; Iino, Y; Maemura, M; Morishita, Y; Owada, S; Sato, H; Sugamata, N; Tago, T; Yokoe, T1
Coombes, RC; Dowsett, M; Mehta, A; Stein, RC1
Klepp, R; Kvinnsland, S; Lønning, PE1
Hayashi, K; Kosaki, G; Shimozuma, K; Tominaga, T; Yoshida, Y1
Demers, L; Entwistle, EA; Kochak, GM; Lipton, A; Mangat, S; Mulagha, MT; Santen, RJ1
Beretta, KR; Bhatnagar, AS; Cavalli, F; Chaudri, HA; Goldhirsch, A; Hoeffken, K; Kvinnsland, S; Trunet, P1
Coombes, RC; Dowsett, M; Moore, J; Powles, TJ; Rubens, R; Smith, IE; Smithers, D; Trunet, PF1
Demers, LM1
Arnold, AP; Hodges, L; Schlinger, BA; Wade, J1
Abe, O; Koyama, H; Nomura, Y; Oohashi, Y; Takashima, S; Wada, T1
Bhatnagar, AS; King, EJ; Purba, HS; Richert, P1
Demers, LM; Hanagan, J; Harvey, HA; Lipton, A; Mulagha, M; Santen, RJ1
Fusani, L; Gahr, M; Hutchison, JB1
Adachi, I; Ikeda, T; Ohashi, Y; Sasaki, Y; Suwa, T; Tabei, T; Takatsuka, Y; Toi, M; Tominaga, T1
Calis, K; Cutler, GB; Feuillan, PP; Jones, J; Nunez, SB1
Hori, H; Kagawa, N; Waterman, MR; Yoshioka, S1
Yahr, P1

Trials

8 trial(s) available for estrone and fadrozole

ArticleYear
The effects of fadrozole hydrochloride on aldosterone secretion in healthy male subjects.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:3

    Topics: Adult; Aldosterone; Cosyntropin; Desoxycorticosterone; Double-Blind Method; Estradiol; Estrogen Antagonists; Estrone; Fadrozole; Furosemide; Humans; Hydrocortisone; Imidazoles; Nitriles; Posture; Reference Values; Renin

1992
Potency and selectivity of the non-steroidal aromatase inhibitor CGS 16949A in postmenopausal breast cancer patients.
    Clinical endocrinology, 1990, Volume: 32, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Estrone; Fadrozole; Female; Gonadal Steroid Hormones; Humans; Imidazoles; Menopause; Middle Aged; Neoplasm Metastasis; Nitriles; Randomized Controlled Trials as Topic

1990
CGS 16949A, a new aromatase inhibitor in the treatment of breast cancer--a phase I study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1990, Volume: 1, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Estradiol; Estrone; Fadrozole; Female; Humans; Hydrocortisone; Imidazoles; Middle Aged; Nitriles; Remission Induction

1990
Endocrine changes with the aromatase inhibitor fadrozole hydrochloride in breast cancer.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aromatase Inhibitors; Breast Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Estradiol; Estrogens; Estrone; Fadrozole; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Postmenopause

1994
Effects of Fadrozole (CGS 16949A) and Letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients.
    Breast cancer research and treatment, 1994, Volume: 30, Issue:1

    Topics: Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens; Estrone; Fadrozole; Female; Humans; Letrozole; Middle Aged; Nitriles; Radioimmunoassay; Triazoles

1994
[Late phase II study of CGS16949A, a new aromatase inhibitor--a multicentral cooperative study (Western Japan Group)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Estradiol; Estrone; Fadrozole; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Postmenopause

1994
The effects of long term fadrozole hydrochloride treatment in patients with advanced stage breast cancer.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Adrenocorticotropic Hormone; Aldosterone; Breast Neoplasms; Estradiol; Estrone; Fadrozole; Female; Humans; Hydrocortisone; Neoplasm Staging

1993
Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrone; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Safety; Survival Rate; Triazoles

2003

Other Studies

12 other study(ies) available for estrone and fadrozole

ArticleYear
Specificity of low dose fadrozole hydrochloride (CGS 16949A) as an aromatase inhibitor.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Fadrozole; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Imidazoles; Kinetics; Menopause; Nitriles

1991
The influence of CGS 16949A on peripheral aromatisation in breast cancer patients.
    British journal of cancer, 1991, Volume: 63, Issue:5

    Topics: Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Estrone; Fadrozole; Female; Humans; Imidazoles; Middle Aged; Nitriles

1991
Antitumor effects of a nonsteroidal aromatase inhibitor (CGS 16949A) on 7, 12-dimethylbenz[alpha]anthracene-induced mammary tumors in rats.
    Japanese journal of clinical oncology, 1991, Volume: 21, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Estradiol; Estrone; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Organ Size; Progesterone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Testosterone; Uterus

1991
Plasma estrone and estrone sulphate in breast cancer patients treated with the aromatase inhibitor CGS 16949A.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:4

    Topics: Aged; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estrone; Fadrozole; Humans; Imidazoles; Male; Middle Aged; Nitriles; Time Factors

1990
Effect of CGS 16949A plus tamoxifen on induced mammary tumours in rats.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrone; Fadrozole; Female; Follicle Stimulating Hormone; Imidazoles; Luteinizing Hormone; Mammary Neoplasms, Experimental; Nitriles; Prolactin; Rats; Rats, Inbred Strains; Tamoxifen

1990
The pharmacodynamic inhibition of estrogen synthesis by fadrozole, an aromatase inhibitor, and its pharmacokinetic disposition.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:5

    Topics: Aged; Aromatase Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation; Estradiol; Estrogens; Estrone; Fadrozole; Female; Humans; Imidazoles; Metabolic Clearance Rate; Middle Aged; Nitriles; Testosterone

1990
Fadrozole: a potent and specific inhibitor of aromatase in the zebra finch brain.
    General and comparative endocrinology, 1994, Volume: 94, Issue:1

    Topics: Androstatrienes; Animals; Aromatase Inhibitors; Birds; Brain; Cells, Cultured; Estradiol; Estrone; Fadrozole; Oxidoreductases; Telencephalon; Testosterone

1994
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:2-3

    Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity

1994
Aromatase inhibition reduces specifically one display of the ring dove courtship behavior.
    General and comparative endocrinology, 2001, Volume: 122, Issue:1

    Topics: Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Columbidae; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Fadrozole; Male; Sexual Behavior, Animal; Testosterone

2001
Lack of efficacy of fadrozole in treating precocious puberty in girls with the McCune-Albright syndrome.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:12

    Topics: Age Determination by Skeleton; Aging; Aromatase Inhibitors; Child; Child, Preschool; Drug Therapy, Combination; Enzyme Inhibitors; Estradiol; Estrone; Fadrozole; Female; Fibrous Dysplasia, Polyostotic; Gonadotropin-Releasing Hormone; Growth; Humans; Menstruation; Ovary; Puberty, Precocious; Treatment Failure; Triptorelin Pamoate; Ultrasonography

2003
Characterization of stable human aromatase expressed in E. coli.
    Steroids, 2004, Volume: 69, Issue:4

    Topics: Amino Acid Sequence; Androstenedione; Arginine; Aromatase; Aromatase Inhibitors; Cell Membrane; Chaperonin 10; Chaperonin 60; Chloramphenicol; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Stability; Escherichia coli; Estradiol; Estrone; Fadrozole; Gene Expression; Humans; Letrozole; Molecular Sequence Data; Nitriles; Polymorphism, Genetic; Protein Structure, Secondary; Protein Synthesis Inhibitors; Recombinant Proteins; Solubility; Testosterone; Triazoles

2004
Two aromatase inhibitors inhibit the ability of a third to promote mating in male rats.
    Hormones and behavior, 2015, Volume: 75

    Topics: Androgens; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Drug Interactions; Estradiol; Estrone; Fadrozole; Female; Male; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reproduction; Sexual Behavior, Animal; Testosterone

2015