Page last updated: 2024-08-17

estrone and estramustine

estrone has been researched along with estramustine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199011 (50.00)18.7374
1990's8 (36.36)18.2507
2000's0 (0.00)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Forsberg, JG; Hoisaeter, PA1
Høisaeter, PA1
Hoisaeter, PA1
Carrell, HL; Duax, WL; Flocco, MM; Glusker, JP; Griffin, JF; Punzi, JS; Strong, P; Tew, KD; Zacharias, DE1
Andersson, SB; Ellman, M; Gunnarsson, PO; Sandberg, AA1
Andrén-Sandberg, A; Björk, P; Jönsson, U1
Andersson, SB; Backman, C; Davidsson, T; Gunnarsson, PO; Johansson, SA1
Andersson, SB; Björk, P; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ1
Sandberg, AA1
Forshell, GP; Gunnarsson, PO1
Björk, P; Forsgren, B1
Shida, K; Yamanaka, H1
Karr, JP; Kirdani, RY; Murphy, GP; Sandberg, AA1
Forshell, GP; Fritjofsson, A; Gunnarsson, PO; Norlén, BJ1
Brooks, M; Dixon, R; Gill, G1
Chen, Z; Keefe, DL; Lin, TT; Naftolin, F; Piepmeier, JM; Weinstein, MA; Yoshida, D; Zielinski, J1
Bergenheim, AT; Edman, K; Gunnarsson, PO; Hariz, MI; Henriksson, R; von Schoultz, E1
Björk, P; Edman, K; Gunnarsson, PO; Hartley-Asp, B; Walz, PH1
Budman, DR; Kreis, W; Liu, XM; Wang, LG1
Brown, CB; Garrett, TE; Mack, JT; Tew, KD; Townsend, DM; Uys, JD1

Reviews

5 review(s) available for estrone and estramustine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Effects of hormone-cytostatic complexes on the rat ventral prostate in vivo and in vitro.
    Vitamins and hormones, 1975, Volume: 33

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amino Acids; Animals; Castration; Cell Nucleus; Cytosol; Dihydrotestosterone; Estradiol; Estramustine; Estrone; Female; Macromolecular Substances; Male; Nitrogen Mustard Compounds; Organ Culture Techniques; Prostate; Rats; Receptors, Cell Surface; Structure-Activity Relationship; Thymidine

1975
Metabolic parameters of Estracyt pertinent to its effects in prostatic cancer.
    Urology, 1984, Volume: 23, Issue:6 Suppl

    Topics: Adenocarcinoma; Animals; Bile; Biotransformation; Estradiol; Estramustine; Estrone; Half-Life; Humans; Hydrocortisone; Hydrolysis; Male; Nitrogen Mustard Compounds; Papio; Prostatic Neoplasms; Time Factors; Tissue Distribution; Transcortin

1984
Clinical pharmacokinetics of estramustine phosphate.
    Urology, 1984, Volume: 23, Issue:6 Suppl

    Topics: Absorption; Dose-Response Relationship, Drug; Estradiol; Estramustine; Estrone; Feces; Half-Life; Humans; Hydrolysis; Kinetics; Male; Metabolic Clearance Rate; Nitrogen Mustard Compounds; Prostatic Neoplasms; Time Factors; Tissue Distribution

1984
Specific binding of estramustine to prostatic proteins.
    Urology, 1984, Volume: 23, Issue:6 Suppl

    Topics: Animals; Carrier Proteins; Cytosol; Epithelium; Estradiol; Estramustine; Estrone; Humans; Male; Nitrogen Mustard Compounds; Organ Specificity; Prostate; Prostatic Neoplasms; Prostatic Secretory Proteins; Protein Binding; Rabbits; Rats

1984

Trials

1 trial(s) available for estrone and estramustine

ArticleYear
Impairment of estramustine phosphate absorption by concurrent intake of milk and food.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:2

    Topics: Aged; Animals; Biological Availability; Chromatography, Gas; Estramustine; Estrone; Food; Humans; Male; Middle Aged; Milk; Nitrogen Mustard Compounds; Prostatic Neoplasms; Radioimmunoassay; Random Allocation; Solubility

1990

Other Studies

16 other study(ies) available for estrone and estramustine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of a steroidal alkylating agent (estramustine phosphate) in rat ventral prostate.
    Scandinavian journal of urology and nephrology. Supplementum, 1977, Issue:46

    Topics: Amino Acids; Animals; Antineoplastic Agents; Cell Nucleus; Dihydrotestosterone; Estradiol; Estramustine; Estrone; Macromolecular Substances; Male; Models, Biological; Nitrogen Mustard Compounds; Organ Culture Techniques; Oxidoreductases; Prostate; Rats; Receptors, Androgen; Receptors, Estrogen; Testosterone; Thymidine

1977
Studies on the conversion of oestradiol linked to a cytostatic agent (Estracyt) in various rat tissues.
    Acta endocrinologica, 1976, Volume: 82, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Estradiol; Estradiol Dehydrogenases; Estramustine; Estrone; Liver; Male; Nitrogen Mustard Compounds; Prostate; Rats; Scintillation Counting

1976
Molecular conformation of estramustine and two analogues.
    Molecular pharmacology, 1992, Volume: 41, Issue:3

    Topics: Estramustine; Estrone; Half-Life; Mechlorethamine; Molecular Conformation; Nitrogen Mustard Compounds; X-Ray Diffraction

1992
Accumulation of estramustine and estromustine in adipose tissue of rats and humans.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:5

    Topics: Adipose Tissue; Aged; Animals; Estramustine; Estrone; Female; Germ-Free Life; Humans; Liver; Male; Middle Aged; Muscles; Nitrogen Mustard Compounds; Pancreatic Neoplasms; Plasma; Preoperative Care; Rats; Rats, Inbred Strains; Time Factors

1991
Binding sites for the cytotoxic metabolites of estramustine phosphate (Estracyt) in rat and human pancreas that are distinct from pancreatic estrogen-binding protein.
    Pancreas, 1991, Volume: 6, Issue:1

    Topics: Aged; Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Chemical Phenomena; Chemistry, Physical; Estradiol; Estramustine; Estrone; Female; Humans; Male; Middle Aged; Molecular Weight; Nitrogen Mustard Compounds; Pancreas; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Receptors, Estrogen

1991
Uptake of estramustine phosphate (estracyt) metabolites in prostatic cancer.
    The Journal of urology, 1988, Volume: 140, Issue:5

    Topics: Aged; Carcinoma; Carrier Proteins; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged; Nitrogen Mustard Compounds; Prostate; Prostatic Neoplasms; Prostatic Secretory Proteins

1988
[Pharmacology and metabolism of a new therapeutic drug for prostatic cancer "Estracyt"].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Estramustine; Estrone; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Mechlorethamine; Nitrogen Mustard Compounds; Prostate; Prostatic Neoplasms; Rats

1984
Prostate cancer; plasma concentrations of estramustine phosphate and its metabolites.
    New York state journal of medicine, 1980, Volume: 80, Issue:9

    Topics: Estradiol; Estramustine; Estrone; Humans; Male; Nitrogen Mustard Compounds; Prostatic Neoplasms

1980
Plasma concentrations of estramustine phosphate and its major metabolites in patients with prostatic carcinoma treated with different doses of estramustine phosphate (Estracyt).
    Scandinavian journal of urology and nephrology, 1981, Volume: 15, Issue:3

    Topics: Administration, Oral; Aged; Carcinoma; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged; Nitrogen Mustard Compounds; Prostatic Neoplasms; Time Factors

1981
Estramustine phosphate: plasma concentrations of its metabolites following oral administration to man, rat and dog.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 27, Issue:1

    Topics: Administration, Oral; Animals; Biotransformation; Dogs; Estradiol; Estramustine; Estrone; Humans; Male; Nitrogen Mustard Compounds; Rats; Species Specificity; Time Factors

1980
Estramustine and estrone analogs rapidly and reversibly inhibit deoxyribonucleic acid synthesis and alter morphology in cultured human glioblastoma cells.
    Neurosurgery, 1993, Volume: 32, Issue:3

    Topics: Brain Neoplasms; Cell Division; Cell Line; DNA Replication; Dose-Response Relationship, Drug; Estramustine; Estrone; Glioblastoma; Humans; Microtubule Proteins; Structure-Activity Relationship; Tumor Cells, Cultured

1993
Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans.
    British journal of cancer, 1993, Volume: 67, Issue:2

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carrier Proteins; Ependymoma; Estramustine; Estrone; Female; Glioma; Humans; Immunohistochemistry; Male; Middle Aged; Nitrogen Mustard Compounds; Prostatic Secretory Proteins

1993
Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Aged; Antineoplastic Agents, Hormonal; Carrier Proteins; Estradiol; Estramustine; Estrone; Humans; Male; Middle Aged; Phosphates; Prostatectomy; Prostatic Neoplasms; Prostatic Secretory Proteins

1998
Androgen antagonistic effect of estramustine phosphate (EMP) metabolites on wild-type and mutated androgen receptor.
    Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9

    Topics: Androgen Antagonists; Antineoplastic Agents, Alkylating; Binding, Competitive; Estramustine; Estrogens; Estrone; Genes, Reporter; HeLa Cells; Humans; Kinetics; Luciferases; Male; Metribolone; Mutagenesis; Nitrogen Mustard Compounds; Prostatic Neoplasms; Receptors, Androgen; Recombinant Proteins; Transcriptional Activation; Transfection; Triamcinolone Acetonide; Tumor Cells, Cultured

1998
Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:6

    Topics: Animals; ATP-Binding Cassette Transporters; Biotransformation; Disease Susceptibility; Estradiol; Estramustine; Estrogens; Estrone; Female; Gastric Mucosa; Intestinal Mucosa; Male; Metabolic Clearance Rate; Mice; Mice, Knockout; Mucositis; Nitric Oxide Synthase Type III; Penile Erection; Penis; Seizures; Sexual Dysfunction, Physiological; Tissue Distribution

2012