Page last updated: 2024-08-17

estrone and digoxin

estrone has been researched along with digoxin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's10 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Pribyl, T; Schreiber, V; Stárka, L; Stĕpán, J1
Ballatori, N; Boyer, JL; Koh, AS; Seward, DJ1
Ferguson, C; Hidalgo, IJ; Kardos, P; Li, J; Owen, A; Strab, R; Wang, Q1
Kamiyama, E; Miura, S; Nakai, D; Okazaki, O; Sugiyama, D1
Abe, T; Goto, J; Hishinuma, T; Mano, N; Mikkaichi, T; Okada, M; Shimada, M; Sugie, M; Toyohara, T; Yamaguchi, H1
Annaert, PP; Augustijns, PF; Baes, M; De Bruyn, T; Peeters, A; Sahi, J; Ye, ZW1
Badolo, L; Brodin, B; Helms, HC; Hersom, M; Kuhlmann, LB; Nielsen, CU1

Reviews

2 review(s) available for estrone and digoxin

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for estrone and digoxin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
[Biological and immunological activity similar to digitalis glycosides of synthetic ACTH and some sex hormone 14-hydroxyderivatives (author's transl)].
    Casopis lekaru ceskych, 1981, May-21, Volume: 120, Issue:20

    Topics: Adrenocorticotropic Hormone; Antigens; Digitoxigenin; Digoxigenin; Digoxin; Erythrocytes; Estradiol; Estrone; Hormones; Humans; Hydroxyestrones; Hydroxytestosterones; Immunoenzyme Techniques; Radioisotopes; Rubidium; Testosterone

1981
Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.
    The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30

    Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Membrane; Cloning, Molecular; Digoxin; Dinoprostone; DNA, Complementary; Dose-Response Relationship, Drug; Epitopes; Estrone; Humans; Kinetics; Liver; Membrane Transport Proteins; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Skates, Fish; Sodium; Steroids; Substrate Specificity; Taurocholic Acid; Tissue Distribution; Xenopus laevis

2003
Application and limitation of inhibitors in drug-transporter interactions studies.
    International journal of pharmaceutics, 2008, May-22, Volume: 356, Issue:1-2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line; Cyclosporine; Digoxin; Dogs; Drug Interactions; Estrone; Humans; Indoles; Kidney; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Permeability; Propionates; Quinolines; Sulfasalazine

2008
Culture period-dependent change of function and expression of ATP-binding cassette transporters in Caco-2 cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Caco-2 Cells; Calcium Channel Blockers; Digoxin; Electric Conductivity; Estrone; Humans; Imidazoles; Leukotriene Antagonists; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Ochratoxins; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Tight Junctions; Time Factors; Verapamil

2009
Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1.
    Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:3

    Topics: Animals; Binding, Competitive; Biological Transport; Cell Line; Chenodeoxycholic Acid; Cyclosporine; Digoxin; Dogs; Epithelial Cells; Estrone; Humans; Kidney; Organic Anion Transporters; Ouabain; Pharmacokinetics; Sulfobromophthalein; Triiodothyronine

2010
Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Jul-17, Volume: 43, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Adolescent; Adult; Biological Transport; Corticosterone; Cryopreservation; Digoxin; Estradiol; Estrone; Hepatocytes; Humans; Male; Membrane Transport Proteins; Middle Aged; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 1; Prazosin; Rifampin; RNA, Messenger; Solute Carrier Organic Anion Transporter Family Member 1B3; Symporters; Taurocholic Acid

2011
An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.
    The AAPS journal, 2014, Volume: 16, Issue:5

    Topics: Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Cattle; Cell Communication; Cell Polarity; Cells, Cultured; Coculture Techniques; Digoxin; Electric Conductivity; Endothelial Cells; Estrone; Etoposide; Kinetics; Mannitol; Multidrug Resistance-Associated Proteins; Permeability; Phenotype; Rats

2014