Page last updated: 2024-08-17

estrone and cyclosporine

estrone has been researched along with cyclosporine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (50.00)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chávez, E; Correa, F; García, G; García, N1
Hu, M; Jeong, EJ; Lin, H1
Hirano, M; Maeda, K; Shitara, Y; Sugiyama, Y1
Gan, LS; Liu, N; Miwa, GT; Xia, CQ1
Häusler, S; Schneiter, R; Stieger, B; Treiber, A1
Imai, S; Kitamura, A; Komuro, S; Yabuki, M1
Ferguson, C; Hidalgo, IJ; Kardos, P; Li, J; Owen, A; Strab, R; Wang, Q1
Abe, T; Goto, J; Hishinuma, T; Mano, N; Mikkaichi, T; Okada, M; Shimada, M; Sugie, M; Toyohara, T; Yamaguchi, H1
Horie, T; Nagamatsu, Y; Shitara, Y; Sugiyama, Y; Takeuchi, K; Wada, S1
Asahi, S; Ebihara, T; Kondo, T; Moriwaki, T; Moriya, Y; Tagawa, Y; Takeuchi, T1

Reviews

2 review(s) available for estrone and cyclosporine

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for estrone and cyclosporine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Dehydroepiandrosterone as an inducer of mitochondrial permeability transition.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 87, Issue:4-5

    Topics: Animals; Calcium; Cattle; Cyclosporine; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Estrone; Intracellular Membranes; Ion Transport; Kidney Cortex; Membrane Potentials; Mitochondria; Mitochondrial Swelling; Oxygen Consumption; Permeability; Rats; Serum Albumin, Bovine; Succinic Acid; Thiobarbituric Acid Reactive Substances

2003
Disposition mechanisms of raloxifene in the human intestinal Caco-2 model.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cyclosporine; Drug Interactions; Estrogen Antagonists; Estrone; Humans; Intestines; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Propionates; Quinolines; Raloxifene Hydrochloride; Time Factors

2004
Drug-drug interaction between pitavastatin and various drugs via OATP1B1.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Cell Line; Cyclosporine; Drug Interactions; Estradiol; Estrone; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Quinolines; Solute Carrier Organic Anion Transporter Family Member 1B3; Transfection

2006
Interactions of cyclosporin a with breast cancer resistance protein.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Cell Membrane Permeability; Cyclosporine; Daunorubicin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrone; Female; Humans; Immunosuppressive Agents; Methotrexate; Mutation; Neoplasm Proteins; Transfection

2007
Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biological Transport; Bosentan; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone Sulfate; Drug Interactions; Enzyme Inhibitors; Estradiol; Estrone; Humans; Liver-Specific Organic Anion Transporter 1; Molecular Structure; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Piperazines; Purines; Pyrimidines; Rifampin; Sildenafil Citrate; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfonamides; Sulfones; Warfarin

2007
The new acyl-CoA cholesterol acyltransferase inhibitor SMP-797 does not interact with statins via OATP1B1 in human cryopreserved hepatocytes and oocytes expressing systems.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:9

    Topics: Binding, Competitive; Biological Transport, Active; Cryopreservation; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Estrone; Fluorobenzenes; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver-Specific Organic Anion Transporter 1; Naphthyridines; Oocytes; Organic Anion Transporters; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Sulfonamides

2007
Application and limitation of inhibitors in drug-transporter interactions studies.
    International journal of pharmaceutics, 2008, May-22, Volume: 356, Issue:1-2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line; Cyclosporine; Digoxin; Dogs; Drug Interactions; Estrone; Humans; Indoles; Kidney; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Permeability; Propionates; Quinolines; Sulfasalazine

2008
Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1.
    Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:3

    Topics: Animals; Binding, Competitive; Biological Transport; Cell Line; Chenodeoxycholic Acid; Cyclosporine; Digoxin; Dogs; Epithelial Cells; Estrone; Humans; Kidney; Organic Anion Transporters; Ouabain; Pharmacokinetics; Sulfobromophthalein; Triiodothyronine

2010
Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.
    Drug metabolism and pharmacokinetics, 2012, Volume: 27, Issue:4

    Topics: Animals; Blotting, Western; Cyclosporine; Dogs; Drug Interactions; Estrone; HEK293 Cells; Hepatocytes; Humans; Immunohistochemistry; Kinetics; Liver-Specific Organic Anion Transporter 1; Madin Darby Canine Kidney Cells; Models, Biological; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Sincalide; Solute Carrier Organic Anion Transporter Family Member 1B3; Tacrolimus; Transfection

2012
Characterization of Transporters in the Hepatic Uptake of TAK-475 M-I, a Squalene Synthase Inhibitor, in Rats and Humans.
    Drug research, 2016, Volume: 66, Issue:6

    Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cyclosporine; Estrone; Farnesyl-Diphosphate Farnesyltransferase; Hepatocytes; Humans; Liver; Oxazepines; Piperidines; Rats

2016