Page last updated: 2024-08-17

estrone and 4-hydroxyestrone

estrone has been researched along with 4-hydroxyestrone in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199017 (34.69)18.7374
1990's8 (16.33)18.2507
2000's13 (26.53)29.6817
2010's8 (16.33)24.3611
2020's3 (6.12)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Ball, P; Knuppen, R1
Chen, F; Lubet, RA; Owens, IS; Ritter, JK; Sheen, YY1
Abul-Hajj, YJ; Cisek, PL1
Knuppen, R1
Aten, RF; Eisenfeld, AJ; Hochberg, RB; MacLusky, NJ1
Ball, P; Emons, G; Haupt, O; Klinger, B1
Nambara, T; Shimada, K; Terashima, E; Yumura, Y1
Fishman, J; Okatani, Y1
Barnea, ER; MacLusky, NJ; Naftolin, F1
Clarke, IJ; Findlay, JK1
Abel, MH; Kelly, RW1
Nambara, T; Shimada, K; Yumura, Y1
Fishman, J; Ikegawa, S1
Haupt, O; Hoppen, HO; Knuppen, R1
Ball, P; Emons, G; Knuppen, R; Mente, C1
Nambara, T; Shimada, K; Tanaka, T1
Ball, P; Emons, G; Hoppen, HO; Knuppen, R1
Berg, D; Kuss, E1
Han, X; Liehr, JG1
Bui, QD; Liehr, JG; Weisz, J; Zhu, BT1
Goto, J; Iwasaki, R; Matsuki, Y; Nambara, T; Suzuki, E1
Service, RF1
Cheng, Z; Coffman, BL; Green, MD; King, CD; Mackenzie, PI; Mojarrabi, B; Rios, GR; Tephly, TR1
Abe, J; Karasawa, S; Matsuki, Y; Suzuki, E1
Duncan, AM; Kurzer, MS; Merz-Demlow, BE; Phipps, WR; Xu, X1
Blond, SY; Bolton, JL; Chen, Y; Constantinou, AI; Elguindi, EC; Hua, Y; Liu, X; Pisha, E; Shen, L; van Breemen, RB; Zhang, F1
Evans, GL; Gibson, KJ; Turner, RT; Westerlind, KC1
Bolton, JL; Constantinou, AI; Lui, X; Pisha, E1
Barry, S; Cantin, AM; Jay-Gerin, JP; Kocsis-Bédard, S; Lemay, R; Paquette, B1
Barrett, JC; Tsutsui, T; Yagi, E1
Frauenhoffer, E; Gestl, SA; Green, MD; Shearer, DA; Tephly, TR; Weisz, J1
Keefer, LK; Saavedra, JE; Waterhouse, DJ; Xu, X; Ziegler, RG1
Cavalieri, EL; Jankowiak, R; Markushin, Y; Rogan, EG; Small, GJ; Yeung, ES; Zhong, W1
Ansell, PJ; Ganjam, VK; Harada, N; Honda, S; Lubahn, DB; Newton, LG; Philips, BJ; Rottinghaus, GE; Welshons, WV1
Conney, AH; Gallo, MA; Kauffman, FC; Li, JJ; Li, SA; Mesia-Vela, S; Reuhl, KR; Sanchez, RI; Thomas, PE; Turan, VK1
Bélanger, A; Brisson, J; Duguay, Y; Guillemette, C; Jacob, S; Lépine, J; Pelletier, G; Perusse, L; Plante, M; Têtu, B; Thibaudeau, J; Tojcic, J1
Cavalieri, EL; Gaikwad, N; Jankowiak, R; Kapke, P; Markushin, Y; Pavlovich, C; Rogan, EG; Trock, BJ; Zhang, H1
Gerschpacher, M; Getoff, N; Hartmann, J; Huber, JC; Quint, RM; Schittl, H1
Kurisu, F; Ogura, M; Saitoh, S; Yagi, O; Yamazoe, A1
Bolton, JL; Chandrasena, ER; Peng, KW; Thatcher, GR; van Breemen, RB; Wang, Z; Yuan, Y1
Berstein, LM; Boyarkina, MP; Imyanitov, EN; Kovalenko, IG; Poroshina, TE; Semiglazov, VF; Vasilyev, DA1
Cui, Y; Guo, L; Li, E; Li, Y; Liu, D; Wang, Y; Zhang, X1
Devoto, L; Henríquez, S; Kohen, P; Muñoz, A; Palomino, WA; Strauss, JF; Veenstra, TD; Xu, X1
Brinton, LA; Chicoine, RE; Falk, RT; Figueroa, JD; Geller, BM; Gierach, GL; Hewitt, SM; Horne, HN; Khodr, ZG; Linville, L; Oh, H; Palakal, M; Papathomas, D; Patel, DA; Pfeiffer, RM; Shepherd, JA; Sherman, ME; Vacek, PM; Veenstra, T; Weaver, DL; Xiang, J; Xu, X1
Altbach, M; Chalasani, P; Chow, HHS; Galons, JP; Huang, C; Maskarinec, G; Roe, DJ; Stopeck, A; Strom, MB; Thompson, PA; Thomson, CA; Wertheim, BC1
Gao, Y; Li, S; Ling, W; Liu, J; Lu, C; Sun, K; Waigi, MG; Williams, MA1
Choi, HJ; Kang, KS; Lee, AJ; Song, JH; Zhu, BT1
Alejandra, GE; Francisco, DC; Lauro, FV; Marcela, RN; Maria, LR; Virginia, MA; Yazmin, OA1

Reviews

1 review(s) available for estrone and 4-hydroxyestrone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Trials

1 trial(s) available for estrone and 4-hydroxyestrone

ArticleYear
A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.
    Breast cancer research and treatment, 2017, Volume: 165, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Female; Humans; Hydroxyestrones; Indoles; Mammography; Middle Aged; Sex Hormone-Binding Globulin; Tamoxifen; Time Factors; Treatment Outcome

2017

Other Studies

47 other study(ies) available for estrone and 4-hydroxyestrone

ArticleYear
Formation of 2- and 4-hydroxyestrogens by brain, pituitary, and liver of the human fetus.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4

    Topics: Brain; Estradiol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Hydroxylation; Liver; Pituitary Gland

1978
Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives.
    Biochemistry, 1992, Apr-07, Volume: 31, Issue:13

    Topics: Binding Sites; Cell Line; Deoxycholic Acid; DNA; Estriol; Estrogens; Glucuronates; Glucuronosyltransferase; Humans; Hydroxyestrones; Isoenzymes; Liver; Molecular Sequence Data; Recombinant Proteins; RNA, Messenger; Sequence Homology, Nucleic Acid; Substrate Specificity; Tissue Distribution; Transfection

1992
Catechol estrogen adducts.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:1

    Topics: Animals; Estrogens, Catechol; Glutathione; Hydroxyestrones; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1988
Mediators of feedback message: estrogens and/or catechol-estrogens?
    Experimental brain research, 1981, Volume: Suppl 3

    Topics: Animals; Catechols; Estrogens; Estrogens, Catechol; Feedback; Female; Gonadotropins, Pituitary; Humans; Hydroxyestrones; Hypothalamo-Hypophyseal System; Menstruation; Ovary; Rats

1981
Separation of steroidal estrogens and their major unconjugated metabolites by high performance liquid chromatography.
    Journal of steroid biochemistry, 1982, Volume: 16, Issue:3

    Topics: Chromatography, High Pressure Liquid; Estradiol; Estrogens; Estrogens, Catechol; Hydroxyestrones

1982
Radioimmunoassay for 4-hydroxyestrone 4-methyl ether in human urine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1982, Volume: 14, Issue:7

    Topics: Estrogens, Catechol; Estrone; Humans; Hydroxyestrones; Radioimmunoassay

1982
In vitro metabolic conjugation of catechol estrogens.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Estrogens, Catechol; Estrogens, Conjugated (USP); Estrone; Female; Glucuronates; Guaiacol; Guinea Pigs; Humans; Hydroxyestrones; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Sulfates

1984
Effects of 2-hydroxyestradiol-17 beta, 2-hydroxyestradiol-17 alpha, and 4-hydroxyestrone on the preovulatory luteinizing hormone surge in the rat: agonist and antagonist actions.
    Endocrinology, 1984, Volume: 115, Issue:3

    Topics: Analysis of Variance; Animals; Estradiol; Estrone; Estrus; Female; Hydroxyestrones; Luteinizing Hormone; Pregnancy; Proestrus; Rats; Rats, Inbred Strains; Time Factors

1984
Kinetics of catechol estrogen-estrogen receptor dissociation: a possible factor underlying differences in catechol estrogen biological activity.
    Steroids, 1983, Volume: 41, Issue:5

    Topics: Animals; Binding, Competitive; Cell Nucleus; Cytosol; Estradiol; Estrone; Female; Hydroxyestrones; Kinetics; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus

1983
Catechol oestrogens and gonadotrophin secretion in the ewe: affinity for pituitary oestrogen receptors invitro and action on gonadotrophin secretion in vivo.
    The Journal of endocrinology, 1980, Volume: 85, Issue:3

    Topics: Animals; Castration; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hydroxyestrones; In Vitro Techniques; Luteinizing Hormone; Pituitary Gland; Receptors, Estrogen; Sheep

1980
A comparison of the effects of 4-catechol oestrogens and 2-pyrogallol oestrogens on prostaglandin synthesis by the rat and human uterus.
    Journal of steroid biochemistry, 1981, Volume: 14, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Estradiol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Uterus

1981
In vitro O-methylation of 4-hydroxyestrone monosulfates.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:6

    Topics: Animals; Catechol O-Methyltransferase; Estrone; Guaiacol; Hydroxyestrones; Male; Methylation; Rats; Rats, Inbred Strains; Sulfates

1982
Synthesis of 3, 6 alpha-trihydroxy-1, 3, 5 (10)-estratrien-17-one 6-hemisuccinate and [6,7 3H]-3,16 alpha-dihydroxy-1,3,5,(10)-estratrien-17-one.
    Steroids, 1982, Volume: 39, Issue:5

    Topics: Chemical Phenomena; Chemistry; Estrone; Hydroxyestrones; Isotope Labeling; Magnetic Resonance Spectroscopy; Methods; Radioimmunoassay; Spectrophotometry, Ultraviolet; Tritium

1982
Synthesis of [2H8] estradiol, [2H7] estrone, [2H6] 2-hydroxyestrone and [2H6] 4-hydroxyestrone as internal standards for selected ion monitoring.
    Steroids, 1982, Volume: 39, Issue:6

    Topics: Deuterium; Estradiol; Estrone; Gas Chromatography-Mass Spectrometry; Hydroxyestrones; Isotope Labeling; Reference Standards

1982
Radioimmunoassay for 4-hydroxyoestrone in human urine.
    Acta endocrinologica, 1981, Volume: 97, Issue:2

    Topics: Adult; Age Factors; Aged; Child; Child, Preschool; Chromatography, Gas; Chromatography, Paper; Cross Reactions; Estrone; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Hydroxyestrones; Male; Middle Aged; Pregnancy; Radioimmunoassay; Receptors, Estrogen; Sex Factors

1981
Studies on steroids. CLXV. Determination of isomeric catechol estrogens in pregnancy urine by high performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1981, Apr-10, Volume: 223, Issue:1

    Topics: Chromatography, High Pressure Liquid; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Isomerism; Pregnancy; Reference Values

1981
4-hydroxyestrone, isolation and identification in human urine.
    Steroids, 1980, Volume: 36, Issue:1

    Topics: Chromatography, Ion Exchange; Estradiol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Pregnancy; Spectrum Analysis

1980
Specific antibodies for radioimmunoassay of 4-hydroxyestrogens and their characterization by 125I-labelled indicator haptens.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1980, Volume: 361, Issue:11

    Topics: Animals; Antibody Formation; Cross Reactions; Estradiol; Estrogens; Estrogens, Catechol; Estrone; Haptens; Hydroxyestrones; Rabbits; Radioimmunoassay

1980
Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Animals; Biotransformation; Cricetinae; DNA; DNA Damage; Equilenin; Estradiol; Estrogens, Catechol; Estrone; Free Radicals; Guanine; Hydroxyestrones; Hydroxylation; Liver; Male; Mesocricetus; Microsomes, Liver; Quinones

1995
Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis.
    Endocrinology, 1994, Volume: 135, Issue:5

    Topics: Animals; Catechol O-Methyltransferase; Cell Transformation, Neoplastic; Chromatography, Gas; Cricetinae; Estrogens; Estrone; Hydroxyestrones; Hydroxylation; Kidney; Male; Mesocricetus; Microsomes; Microsomes, Liver; Steroid 16-alpha-Hydroxylase

1994
Synthesis of N-acetylcysteine conjugates of catechol estrogens.
    Steroids, 1996, Volume: 61, Issue:5

    Topics: Acetylcysteine; Estrogens, Catechol; Hydroxyestrones; Magnetic Resonance Spectroscopy; Molecular Structure

1996
New role for estrogen in cancer?
    Science (New York, N.Y.), 1998, Mar-13, Volume: 279, Issue:5357

    Topics: Animals; Carcinogens; Estrogens; Female; Humans; Hydroxyestrones; Mutagens; Neoplasms

1998
Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 45, Issue:1

    Topics: Estradiol; Estrogens, Catechol; Flunitrazepam; Glucuronates; Glucuronosyltransferase; Humans; Hydroxyestrones; Isoenzymes; Norepinephrine

1998
Enzymic and chemical O-methylation of a 4-hydroxyestrone N-acetylcysteine conjugate.
    Steroids, 1998, Volume: 63, Issue:12

    Topics: Acetylcysteine; Animals; Enzymes; Hydroxyestrones; Kinetics; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Molecular Structure; Rats; Spectrophotometry, Ultraviolet

1998
Menstrual cycle effects on urinary estrogen metabolites.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:11

    Topics: Adult; Body Weight; Diet; Estradiol; Estrogens; Estrogens, Catechol; Estrone; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Luteal Phase; Menstruation; Ovulation

1999
A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
    Chemical research in toxicology, 2000, Volume: 13, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Survival; Comet Assay; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelial Cells; Equilenin; Estradiol Congeners; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Tumor Cells, Cultured

2000
The catechol estrogen, 4-hydroxyestrone, has tissue-specific estrogen actions.
    The Journal of endocrinology, 2000, Volume: 167, Issue:2

    Topics: Animals; Body Weight; Bone and Bones; Bone Remodeling; Cholesterol; Estradiol; Female; Growth; Hydroxyestrones; Mammary Glands, Animal; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Uterus

2000
Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro.
    Chemical research in toxicology, 2001, Volume: 14, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Epidermal Cells; Epidermis; Equilenin; Estradiol Congeners; Fibroblasts; Horses; Hydroxyestrones; Mice; Mice, Inbred C3H; Reactive Oxygen Species

2001
In vitro generation of peroxynitrite by 2- and 4-hydroxyestrogens in the presence of nitric oxide.
    Chemical research in toxicology, 2001, Volume: 14, Issue:5

    Topics: Chromatography, High Pressure Liquid; Estradiol; Estrogens, Catechol; Hydroxyestrones; Mass Spectrometry; Nitrates; Nitric Oxide

2001
The ability of four catechol estrogens of 17beta-estradiol and estrone to induce DNA adducts in Syrian hamster embryo fibroblasts.
    Carcinogenesis, 2001, Volume: 22, Issue:9

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; DNA Adducts; Estradiol; Estrogens, Catechol; Fibroblasts; Hydroxyestrones; Mesocricetus

2001
Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers.
    The American journal of pathology, 2002, Volume: 160, Issue:4

    Topics: Breast; Breast Neoplasms; Female; Glucuronosyltransferase; Humans; Hydroxyestrones; Immunoblotting; Immunohistochemistry; Neoplasm Invasiveness; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Tretinoin

2002
Stable isotope dilution high-performance liquid chromatography-electrospray ionization mass spectrometry method for endogenous 2- and 4-hydroxyestrones in human urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Nov-25, Volume: 780, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Hydrolysis; Hydroxyestrones; Isotopes; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2002
Spectral characterization of catechol estrogen quinone (CEQ)-derived DNA adducts and their identification in human breast tissue extract.
    Chemical research in toxicology, 2003, Volume: 16, Issue:9

    Topics: Breast Neoplasms; Chromatography, High Pressure Liquid; DNA Adducts; Electrochemistry; Electrophoresis, Capillary; Estradiol; Estrogens, Catechol; Female; Forecasting; Humans; Hydroxyestrones; Luminescent Measurements; Mammary Glands, Human; Purines; Spectrum Analysis; Tissue Extracts

2003
Estrogen receptor-independent catechol estrogen binding activity: protein binding studies in wild-type, Estrogen receptor-alpha KO, and aromatase KO mice tissues.
    Biochemistry, 2004, Jun-01, Volume: 43, Issue:21

    Topics: Animals; Aromatase; Binding, Competitive; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens, Catechol; Female; Fulvestrant; Hydroxyestrones; Kidney; Liver; Male; Mice; Mice, Knockout; Ovary; Proteins; Receptors, Estrogen; Substrate Specificity; Tissue Distribution; Uterus

2004
The effects of steroidal estrogens in ACI rat mammary carcinogenesis: 17beta-estradiol, 2-hydroxyestradiol, 4-hydroxyestradiol, 16alpha-hydroxyestradiol, and 4-hydroxyestrone.
    The Journal of endocrinology, 2004, Volume: 183, Issue:1

    Topics: Animals; Carcinoma in Situ; Carcinoma, Ductal, Breast; Dose-Response Relationship, Drug; Drug Implants; Estradiol; Estriol; Estrogens; Estrogens, Catechol; Female; Hydroxyestrones; Mammary Neoplasms, Experimental; Rats; Rats, Inbred ACI

2004
Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.
    Cancer research, 2006, Jan-01, Volume: 66, Issue:1

    Topics: Biotransformation; Breast; Cell Line, Tumor; Codon; Estradiol; Estrogens, Catechol; Estrone; Female; Glucuronosyltransferase; Humans; Hydroxyestrones; Hydroxylation; Isoenzymes; Kinetics; Linkage Disequilibrium; Uterus

2006
Potential biomarker for early risk assessment of prostate cancer.
    The Prostate, 2006, Oct-01, Volume: 66, Issue:14

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; DNA Adducts; Early Diagnosis; Electrophoresis, Capillary; Estradiol; Estrogens, Catechol; Humans; Hydroxyestrones; Male; Prostatic Neoplasms; Risk Factors

2006
The 4-hydroxyestrone: Electron emission, formation of secondary metabolites and mechanisms of carcinogenesis.
    Journal of photochemistry and photobiology. B, Biology, 2010, Jan-21, Volume: 98, Issue:1

    Topics: Carcinogens; Electrons; Estradiol; Hydroxyestrones; Quantum Theory; Ultraviolet Rays

2010
Degradation of natural estrogen and identification of the metabolites produced by soil isolates of Rhodococcus sp. and Sphingomonas sp.
    Journal of bioscience and bioengineering, 2010, Volume: 109, Issue:6

    Topics: Catechols; Estradiol; Estrogens; Estrogens, Catechol; Estrone; Hydroxyestrones; Rhodococcus; Soil Microbiology; Sphingomonas

2010
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.
    Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Cell Line, Tumor; Chelating Agents; Copper; Deoxyguanosine; DNA; DNA Damage; DNA, Neoplasm; Equilenin; Estrogens, Catechol; Free Radical Scavengers; Horses; Humans; Hydrogen Peroxide; Hydroxyestrones; Molecular Structure; NADP; Oxidation-Reduction; Reactive Oxygen Species; Structure-Activity Relationship

2010
Endocrine metabolic disorders in patients with breast cancer, carriers of BRCA1 gene mutations.
    Bulletin of experimental biology and medicine, 2012, Volume: 152, Issue:5

    Topics: Blood Glucose; BRCA1 Protein; Breast Neoplasms; C-Peptide; Endocrine System; Estradiol; Female; Humans; Hydroxyestrones; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Lipoproteins; Middle Aged; Mutation; Reactive Oxygen Species; Sex Hormone-Binding Globulin; Thyrotropin; Triglycerides

2012
Metabolomic analysis of serum from obese adults with hyperlipemia by UHPLC-Q-TOF MS/MS.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Humans; Hydroxyestrones; Hyperlipidemias; Male; Metabolomics; Middle Aged; Obesity; Serum; Tandem Mass Spectrometry; Young Adult

2016
Estrogen metabolites in human corpus luteum physiology: differential effects on angiogenic activity.
    Fertility and sterility, 2016, Volume: 106, Issue:1

    Topics: 2-Methoxyestradiol; Biotransformation; Cell Line; Chorionic Gonadotropin; Corpus Luteum; Endothelial Cells; Estradiol; Estrogens; Estrone; Female; Granulosa Cells; Healthy Volunteers; Humans; Hydroxyestrones; Neovascularization, Physiologic; Progesterone; Vascular Endothelial Growth Factor A

2016
Relation of Serum Estrogen Metabolites with Terminal Duct Lobular Unit Involution Among Women Undergoing Diagnostic Image-Guided Breast Biopsy.
    Hormones & cancer, 2016, Volume: 7, Issue:5-6

    Topics: Adult; Breast; Breast Neoplasms; Chromatography, Liquid; Cross-Sectional Studies; Estradiol; Female; Humans; Hydroxyestrones; Image-Guided Biopsy; Middle Aged; Postmenopause; Premenopause; Tandem Mass Spectrometry

2016
Metabolism of 17β-estradiol by Novosphingobium sp. ES2-1 as probed via HRMS combined with
    Journal of hazardous materials, 2020, 05-05, Volume: 389

    Topics: Carbon Isotopes; Estradiol; Estrogens; Estrone; Hydroxyestrones; Isotope Labeling; Mass Spectrometry; Sphingomonadaceae

2020
4-Hydroxyestrone, an Endogenous Estrogen Metabolite, Can Strongly Protect Neuronal Cells Against Oxidative Damage.
    Scientific reports, 2020, 04-29, Volume: 10, Issue:1

    Topics: Animals; Cell Line, Transformed; Estradiol; Hippocampus; Hydroxyestrones; Male; Mice; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Sprague-Dawley

2020
Effective synthesis of a hexacyclic-steroid derivative from 4-hydroxyestrone.
    Steroids, 2020, Volume: 163

    Topics: Chemistry Techniques, Synthetic; Heterocyclic Compounds, 4 or More Rings; Hydroxyestrones

2020