estrone has been researched along with 2-methoxyestrone in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (60.87) | 18.7374 |
| 1990's | 6 (13.04) | 18.2507 |
| 2000's | 7 (15.22) | 29.6817 |
| 2010's | 3 (6.52) | 24.3611 |
| 2020's | 2 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Adamski, J; Deluca, D; Droescher, P; Elger, W; Gege, C; Hillisch, A; Kowalik, D; Möller, G; Peters, O; Rosinus, A | 1 |
| Cortés-Benítez, F; Dutour, R; Poirier, D; Roy, J | 1 |
| Ball, P; Knuppen, R; Reu, G; Schwab, J | 1 |
| Archer, RD; Lewis, KM | 1 |
| Kennedy, JA | 1 |
| Berg, FD; Kuss, E | 1 |
| Higa, H | 1 |
| Bradlow, HL; Fishman, J; Haley, NJ; Hershcopf, RJ; Michnovicz, JJ | 1 |
| Murphy, BE; Philip, A | 2 |
| Brueggemeier, RW; Singh, U | 1 |
| Higa, H; Kono, S; Matsumura, M; Sunagawa, H; Takenaka, S | 1 |
| Higa, H; Kono, S; Sunagawa, H | 1 |
| Higa, H; Kono, S; Matsumura, M; Sunagawa, H | 1 |
| Bradlow, HL; Fishman, J; Hershcopf, RJ; Michnovicz, JJ; Naganuma, H | 1 |
| Jellinck, PH; Newcombe, AM | 1 |
| Berg, D; Kuss, E; Warnecke, HH | 1 |
| Martucci, CP | 1 |
| Baxter, CR; Casey, ML; MacDonald, PC; Simpson, ER; Smith, JW | 1 |
| Femino, A; Flood, C; Longcope, C; Williams, KI | 2 |
| Brandon, DD; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 1 |
| Bradlow, HL; Fishman, J; Kunkel, HG; Lahita, RG | 1 |
| Fishman, J; Katayama, S | 1 |
| MacLusky, NJ; Merriam, GR; Naftolin, F; Picard, MK | 1 |
| Eng, FC; Ferrara, J; Lee, HS; White, JH; Willson, TM | 1 |
| Lippert, TH; Mueck, AO; Seeger, H | 2 |
| Hejaz, HA; MacCarthy-Morrogh, L; Packham, G; Potter, BV; Purohit, A; Reed, MJ; Walden, L | 1 |
| Hejaz, HA; Potter, BV; Purohit, A; Reed, MJ; Singh, A | 1 |
| MacCarthy-Morrogh, L; Packham, G; Purohit, A; Reed, MJ; Townsend, PA | 1 |
| Comninos, A; Day, JM; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Solomon, C | 1 |
| GALLAGHER, TF; KRAYCHY, S | 1 |
| LOKE, KH; MARRIAN, GF | 1 |
| BAULD, WS; GIVNER, ML; VAGI, K | 2 |
| AXELROD, LR; GOLDZIEHER, JW; RAO, PN | 1 |
| FRANDSEN, VA | 1 |
| HOBKIRK, R; NILSEN, M | 1 |
| MATSUMOTO, K; SEKI, T | 1 |
| Breen, T; Matei, D; Perkins, S; Quon, C; Schilder, J; Sidor, C; Sutton, G | 1 |
| Abrams, TA; Blaszkowsky, LS; Chan, JA; Fuchs, CS; Kulke, MH; Meyerhardt, JA; Regan, E; Sidor, C; Zhu, AX | 1 |
| Devoto, L; Henríquez, S; Kohen, P; Muñoz, A; Palomino, WA; Strauss, JF; Veenstra, TD; Xu, X | 1 |
| Ji, J; Sun, J; Sun, X; Xu, S; Zhang, Y | 1 |
| Aprikian, A; Carmel, M; Caron, P; Chevalier, S; Emond, JP; Guillemette, C; Lacombe, L; Lévesque, E; Saad, F; Simonyan, D; Turcotte, V | 1 |
2 trial(s) available for estrone and 2-methoxyestrone
| Article | Year |
|---|---|
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial.
Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Peritoneal Neoplasms | 2009 |
A prospective phase II study of 2-methoxyestradiol administered in combination with bevacizumab in patients with metastatic carcinoid tumors.
Topics: 2-Methoxyestradiol; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoid Tumor; Cohort Studies; Estradiol; Female; Gastrointestinal Neoplasms; Humans; Hydroxyestrones; Male; Middle Aged; Neoplasm Staging; Patient Dropouts; Survival Analysis; Tumor Burden; Vascular Endothelial Growth Factor A | 2011 |
44 other study(ies) available for estrone and 2-methoxyestrone
| Article | Year |
|---|---|
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Structure-based design, synthesis and in vitro characterization of potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone.
Topics: 17-Hydroxysteroid Dehydrogenases; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Estrone; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2009 |
Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives.
Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Estrogens; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2016 |
Radioimmunoassay of 2-hydroxyesterone and 2-methoxyestrone in human urine.
Topics: Adult; Age Factors; Child; Estrone; Female; Humans; Hydroxyestrones; Isotope Labeling; Male; Ovulation; Radioimmunoassay; Sex Factors | 1979 |
pKa values of estrone, 17 beta-estradiol and 2-methoxyestrone.
Topics: Estradiol; Estrone; Hydroxyestrones; Ions; Spectrophotometry, Ultraviolet | 1979 |
Effect of catechol oestrogens on extraneuronal metabolism of noradrenaline by rabbit uterine endometrium and myometrium.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase Inhibitors; Endometrium; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Methylation; Monoamine Oxidase Inhibitors; Myometrium; Norepinephrine; Rabbits; Tritium | 1991 |
Urinary excretion of catecholestrogens, 2-methoxy-estrogens and "classical estrogens" throughout the normal menstrual cycle.
Topics: 2-Methoxyestradiol; Adult; Estradiol; Estrogens; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Menstrual Cycle; Radioimmunoassay; Reference Values | 1991 |
[Effects of catecholestrogen and catecholestrogen 2-monomethyl ether on serum lipids and lipoproteins in rats].
Topics: Animals; Cholesterol; Cholesterol, HDL; Diet; Estradiol; Estriol; Female; Hydroxyestrones; Hypercholesterolemia; Ovariectomy; Rats; Rats, Inbred Strains; Triglycerides | 1990 |
Cigarette smoking alters hepatic estrogen metabolism in men: implications for atherosclerosis.
Topics: Adult; Arteriosclerosis; Estriol; Estrogens; Humans; Hydroxyestrones; Hydroxylation; Liver; Male; Middle Aged; Smoking | 1989 |
Low polarity ligands of sex hormone-binding globulin in pregnancy. Part II--Identification.
Topics: 5-alpha-Dihydroprogesterone; Chromatography, High Pressure Liquid; Estrenes; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Hydroxyestrones; Labor Onset; Nandrolone; Pregnancy; Pregnanediones; Progesterone; Sex Hormone-Binding Globulin | 1989 |
Inhibition of rat liver microsomal estrogen 2-hydroxylase by 2-methoxyestrogens.
Topics: 2-Methoxyestradiol; Animals; Cytochrome P-450 CYP1A1; Estradiol; Estrone; Hydroxyestrones; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Steroid Hydroxylases | 1989 |
Hypolipidemic effects of catecholestrogen and 2-methoxy-catecholestrogen.
Topics: Animals; Cholesterol; Cholesterol, HDL; Estrogens, Catechol; Female; Hydroxyestrones; Hyperlipidemias; Rats; Rats, Inbred Strains; Triglycerides | 1985 |
Effects of catecholestrogen 2-monomethyl ether on serum cholesterol and lipoprotein levels.
Topics: Animals; Cholesterol; Estriol; Estrone; Female; Hydroxyestrones; Hypercholesterolemia; Lipoproteins; Rats; Rats, Inbred Strains | 1988 |
Relative binding of certain steroids of low polarity to human sex hormone-binding globulin: strong binding of 2-methoxyestrone, a steroid lacking the 17 beta-OH group.
Topics: Binding, Competitive; Estrone; Humans; Hydroxyestrones; Hydroxylation; Progesterone; Sex Hormone-Binding Globulin; Testosterone | 1986 |
[Hypocholesterolemic effect of catechol estrogen 2-monomethyl ether].
Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Estradiol; Estriol; Estrone; Female; Hydroxyestrones; Organ Size; Rats; Rats, Inbred Strains; Uterus | 1987 |
Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking.
Topics: Adult; Estradiol; Estrogens; Female; Humans; Hydroxyestrones; Hydroxylation; Menopause; Menstrual Cycle; Smoking; Steroid 16-alpha-Hydroxylase | 1986 |
Effect of catechol estrogens and estriol on the induction of uterine peroxidase.
Topics: Animals; Catechols; Enzyme Induction; Estradiol; Estriol; Estrogens; Estrogens, Catechol; Female; Hydroxyestrones; Peroxidases; Rats; Structure-Activity Relationship; Uterus | 1980 |
Synthesis of immunogenic C-6 derivatives of 2-methoxyestrone and 2-methoxyestradiol-17 beta and characterization of the corresponding antisera.
Topics: 2-Methoxyestradiol; Animals; Cattle; Cross Reactions; Estradiol; Estrogens, Conjugated (USP); Estrone; Hydroxyestrones; Immune Sera; Indicators and Reagents; Rabbits; Radioimmunoassay; Serum Albumin, Bovine | 1982 |
The role of 2-methoxyestrone in estrogen action.
Topics: Aging; Animals; Animals, Newborn; Brain; Estrogens; Estrogens, Catechol; Estrone; Female; Hydroxyestrones; Liver; Male; Rats; Receptors, Estrogen; Structure-Activity Relationship; Tissue Distribution; Uterine Contraction; Uterus | 1983 |
Catechol-O-methyltransferase activity in erythrocytes of persons with severe thermal injury.
Topics: Adult; Anemia; Burns; Catechol O-Methyltransferase; Erythrocytes; Female; Humans; Hydroxyestrones; Male | 1983 |
Metabolism of 2-methoxyestrone in normal men.
Topics: Adult; Carbon Radioisotopes; Estrone; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Middle Aged; Tritium | 1983 |
Radioimmunoassay and metabolism of the catechol estrogen 2-hydroxyestradiol.
Topics: 2-Methoxyestradiol; Adult; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Estradiol; Female; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Middle Aged; Radioimmunoassay | 1982 |
Metabolic clearance rate and conversion ratios of [3H]2-hydroxyestrone in normal men.
Topics: Adult; Estrone; Glucuronates; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Sulfates | 1982 |
Abnormal estrogen and androgen metabolism in the human with systemic lupus erythematosus.
Topics: Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Lupus Erythematosus, Systemic; Male; Oxidation-Reduction; Testosterone | 1982 |
2-Hydroxyestrone suppresses and 2-methoxyestrone augments the preovulatory prolactin surge in the cycling rat.
Topics: Animals; Estradiol; Estrone; Female; Hydroxyestrones; Ovulation; Pregnancy; Proestrus; Prolactin; Rats | 1982 |
Comparative properties of the catechol estrogens, I: methylation by catechol-O-methyltransferase and binding to cytosol estrogen receptors.
Topics: 2-Methoxyestradiol; Animals; Binding Sites; Catechol O-Methyltransferase; Cytosol; Estradiol; Estriol; Female; Hydroxyestrones; Hypothalamus; Liver; Methylation; Pituitary Gland; Rats; Receptors, Estrogen; Substrate Specificity; Uterus | 1980 |
Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; COS Cells; Estradiol; Estrogen Antagonists; Estrone; HSP90 Heat-Shock Proteins; Hydroxyestrones; Ligands; Molecular Sequence Data; Mutation; Nuclear Proteins; Polyunsaturated Alkamides; Receptors, Estrogen; Saccharomyces cerevisiae; Sequence Alignment; Tamoxifen; Transcriptional Activation | 1997 |
Effect of estradiol metabolites on the susceptibility of low density lipoprotein to oxidation.
Topics: Estradiol; Estrogens, Catechol; Humans; Hydroxyestrones; Kinetics; Lipoproteins, LDL; Oxidation-Reduction; Vitamin E | 1997 |
Effect of estradiol metabolites on prostacyclin synthesis in human endothelial cell cultures.
Topics: 2-Methoxyestradiol; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Estradiol; Estrone; Humans; Hydroxyestrones | 1999 |
The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle; Cell Division; Estrone; Female; G2 Phase; Humans; Hydroxyestrones; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitosis; Rats; Receptors, Estrogen; Tumor Cells, Cultured | 2000 |
Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Biological Transport, Active; Breast Neoplasms; Deoxyglucose; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Insulin; Kinetics; Paclitaxel; Tumor Cells, Cultured | 2000 |
Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic. Arrest, apoptosis, and microtubule assembly in human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Estrone; Humans; Hydroxyestrones; Microtubules; Mitosis; Tubulin; Tumor Cells, Cultured | 2000 |
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Division; Cell Separation; Estradiol; Estrone; Female; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyestrones; Immunoblotting; Inhibitory Concentration 50; Male; Mitosis; Models, Chemical; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured | 2003 |
2-Methoxyestrone, a new metabolite of estradiol-17 beta in man.
Topics: Estradiol; Humans; Hydroxyestrones; Male | 1957 |
Isolation of 2-methoxyoestrone from the urine of pregnant women.
Topics: Body Fluids; Estrogens; Hydroxyestrones; Pregnancy | 1958 |
A chemical method for the quantitative determination of 2-methoxyoestrone, oestrone, ring D alpha-ketolic oestrogens, oestradiol-17beta, 16-epioestriol and oestriol in human urine.
Topics: Estradiol; Estriol; Estrogens; Estrone; Humans; Hydroxyestrones | 1960 |
A method for the quantitative fractionation of mixtures of 2-methoxyoestrone, oestrone, ring D alpha-ketolic oestrogens, oestradiol-17beta, 16-epioestriol and oestriol by partition chromatography and the Girard reaction.
Topics: Chromatography, Liquid; Estradiol; Estriol; Estrogens; Estrone; Hydroxyestrones | 1960 |
Methylation of 2-hydroxyestradiol-17beta to 2-methoxyestrone in the human.
Topics: Biochemical Phenomena; Estradiol; Estrogens; Humans; Hydroxyestrones; Methylation | 1960 |
The demonstration of 2-methoxyoestrone and of 2-methoxyoestradiol in human pregnancy urine.
Topics: 2-Methoxyestradiol; Estradiol; Estradiol Congeners; Estrogens; Hydroxyestrones; Pregnancy | 1959 |
2-methoxyestrone as an estrogen metabolite in the human subject.
Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Hydroxyestrones | 1963 |
CHROMATOGRAPHIC SEPARATION OF ESTRIOL, 16-KETOESTRADIOL-17BETA, 16-EPIESTRIOL, ESTRADIOL-17ALPHA, ESTRADIOL-17BETA, ESTRONE AND 2-METHOXYESTRONE ON THE COLUMN OF PARTIALLY ESTERIFIED CARBOXYLIC ACID TYPE ION EXCHANGE RESIN.
Topics: Carboxylic Acids; Chromatography; Estradiol; Estradiol Congeners; Estriol; Estrogens; Estrone; Hydroxyestrones; Ion Exchange; Ion Exchange Resins | 1963 |
Estrogen metabolites in human corpus luteum physiology: differential effects on angiogenic activity.
Topics: 2-Methoxyestradiol; Biotransformation; Cell Line; Chorionic Gonadotropin; Corpus Luteum; Endothelial Cells; Estradiol; Estrogens; Estrone; Female; Granulosa Cells; Healthy Volunteers; Humans; Hydroxyestrones; Neovascularization, Physiologic; Progesterone; Vascular Endothelial Growth Factor A | 2016 |
Opposite estrogen effects of estrone and 2-hydroxyestrone on MCF-7 sensitivity to the cytotoxic action of cell growth, oxidative stress and inflammation activity.
Topics: Cell Proliferation; Endocrine Disruptors; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Inflammation; MCF-7 Cells; Molecular Docking Simulation; Oxidative Stress; Toxicity Tests | 2021 |
Urinary oestrogen steroidome as an indicator of the risk of localised prostate cancer progression.
Topics: Aged; Disease Progression; Estradiol; Humans; Hydroxyestrones; Male; Mass Spectrometry; Middle Aged; Prospective Studies; Prostatic Neoplasms | 2021 |