estrone has been researched along with 2-methoxyestradiol in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (16.22) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 12 (32.43) | 29.6817 |
| 2010's | 10 (27.03) | 24.3611 |
| 2020's | 3 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cortés-Benítez, F; Dutour, R; Poirier, D; Roy, J | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Kennedy, JA | 1 |
| Berg, FD; Kuss, E | 1 |
| Brueggemeier, RW; Singh, U | 1 |
| Hammond, JM; Mondschein, JS; Weisz, J | 1 |
| Berg, D; Kuss, E; Warnecke, HH | 1 |
| Brandon, DD; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 1 |
| MacLusky, NJ; Merriam, GR; Naftolin, F; Picard, MK | 1 |
| Adlercreutz, H; Carson, M; Loukovaara, M | 1 |
| Antoniak, SK; Evaristus, EN; Liehr, JG; Ricci, MJ; Sarabia, SF; Zhu, BT | 1 |
| Lippert, TH; Mueck, AO; Seeger, H | 3 |
| Hejaz, HA; Potter, BV; Purohit, A; Reed, MJ; Singh, A | 1 |
| Gruber, DM; Huber, JC | 1 |
| Ikeda, N; Nakashima, S; Oda, T; Sato, Y | 1 |
| Comninos, A; Day, JM; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Solomon, C | 1 |
| FRANDSEN, VA | 1 |
| Albanese, C; Gallo, MA; Lewis, JS; Pestell, RG; Thomas, T; Thomas, TJ | 1 |
| Breen, T; Matei, D; Perkins, S; Quon, C; Schilder, J; Sidor, C; Sutton, G | 1 |
| Agoston, GE; Hunsucker, K; LaVallee, TM; Pribluda, V; Shah, JH; Suwandi, L; Swartz, GM; Treston, AM; Zhan, XH | 1 |
| Bertone-Johnson, ER; Bigelow, C; Heersink, J; Kurzer, MS; Puleo, E; Sabelawski, S; Sturgeon, SR; Volpe, SL; Wahala, K | 1 |
| Abrams, TA; Blaszkowsky, LS; Chan, JA; Fuchs, CS; Kulke, MH; Meyerhardt, JA; Regan, E; Sidor, C; Zhu, AX | 1 |
| Negi, AS; Prakasham, AP; Shanker, K | 1 |
| Blair, IA; Colón-Otero, G; Hossain, J; Mauras, N; Mesaros, C; Santen, RJ; Wang, Q | 1 |
| Brinton, LA; Dallal, CM; Falk, RT; Garcia-Closas, M; Gierach, GL; Hartman, TJ; Lissowska, J; Matthews, CE; Pfeiffer, RM; Veenstra, TD; Xu, X | 1 |
| Devoto, L; Henríquez, S; Kohen, P; Muñoz, A; Palomino, WA; Strauss, JF; Veenstra, TD; Xu, X | 1 |
| Anderson, GL; Arem, H; Brinton, LA; Cauley, JA; Chen, C; Coburn, SB; Falk, RT; Goodman, D; Matthews, CE; Oh, H; Pfeiffer, RM; Reding, KW; Trabert, B; Wentzensen, N; Xu, X | 1 |
| Bonfoh, SI; Du, Z; Jiang, H; Li, D; Xiong, C; Xiong, X | 1 |
| Kulbacka, J; Piwowar, A; Roik, J; Saczko, J; Sawicka, E | 1 |
| Balogh, GT; Frank, É; Kinyua, NI; Leits, P; Minorics, R; Molnár, B; Mótyán, G; Zupkó, I | 1 |
4 review(s) available for estrone and 2-methoxyestradiol
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Conjugated estrogens--the natural SERMs.
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Cardiovascular Diseases; Dihydrotestosterone; Equilin; Estradiol; Estradiol Congeners; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxyestrones; Osteoporosis; Progesterone; Selective Estrogen Receptor Modulators; Testosterone; Thyroxine; Triiodothyronine | 1999 |
Estradiol metabolism and malignant disease.
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Estradiol; Estriol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Molecular Structure; Neoplasms | 2002 |
[Estrogen-dependent neoplasia - what is the significance of estradiol metabolites].
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Breast Neoplasms; Estradiol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Male; Neovascularization, Pathologic; Neovascularization, Physiologic; Postmenopause; Prostatic Neoplasms | 2003 |
2 trial(s) available for estrone and 2-methoxyestradiol
| Article | Year |
|---|---|
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial.
Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Peritoneal Neoplasms | 2009 |
A prospective phase II study of 2-methoxyestradiol administered in combination with bevacizumab in patients with metastatic carcinoid tumors.
Topics: 2-Methoxyestradiol; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoid Tumor; Cohort Studies; Estradiol; Female; Gastrointestinal Neoplasms; Humans; Hydroxyestrones; Male; Middle Aged; Neoplasm Staging; Patient Dropouts; Survival Analysis; Tumor Burden; Vascular Endothelial Growth Factor A | 2011 |
31 other study(ies) available for estrone and 2-methoxyestradiol
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives.
Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Estrogens; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of catechol oestrogens on extraneuronal metabolism of noradrenaline by rabbit uterine endometrium and myometrium.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase Inhibitors; Endometrium; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Methylation; Monoamine Oxidase Inhibitors; Myometrium; Norepinephrine; Rabbits; Tritium | 1991 |
Urinary excretion of catecholestrogens, 2-methoxy-estrogens and "classical estrogens" throughout the normal menstrual cycle.
Topics: 2-Methoxyestradiol; Adult; Estradiol; Estrogens; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Menstrual Cycle; Radioimmunoassay; Reference Values | 1991 |
Inhibition of rat liver microsomal estrogen 2-hydroxylase by 2-methoxyestrogens.
Topics: 2-Methoxyestradiol; Animals; Cytochrome P-450 CYP1A1; Estradiol; Estrone; Hydroxyestrones; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Steroid Hydroxylases | 1989 |
Characteristics of estrogen-2/4-hydroxylase of porcine ovarian follicles: influence of steroidal and non-steroidal agents on the activity of the enzyme in vitro.
Topics: 2-Methoxyestradiol; Animals; Catecholamines; Catechols; Cytochrome P-450 CYP1A1; Estradiol; Estrogens; Estrone; Female; In Vitro Techniques; Ovary; Proadifen; Progesterone; Steroid Hydroxylases; Swine | 1987 |
Synthesis of immunogenic C-6 derivatives of 2-methoxyestrone and 2-methoxyestradiol-17 beta and characterization of the corresponding antisera.
Topics: 2-Methoxyestradiol; Animals; Cattle; Cross Reactions; Estradiol; Estrogens, Conjugated (USP); Estrone; Hydroxyestrones; Immune Sera; Indicators and Reagents; Rabbits; Radioimmunoassay; Serum Albumin, Bovine | 1982 |
Radioimmunoassay and metabolism of the catechol estrogen 2-hydroxyestradiol.
Topics: 2-Methoxyestradiol; Adult; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Estradiol; Female; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Middle Aged; Radioimmunoassay | 1982 |
Comparative properties of the catechol estrogens, I: methylation by catechol-O-methyltransferase and binding to cytosol estrogen receptors.
Topics: 2-Methoxyestradiol; Animals; Binding Sites; Catechol O-Methyltransferase; Cytosol; Estradiol; Estriol; Female; Hydroxyestrones; Hypothalamus; Liver; Methylation; Pituitary Gland; Rats; Receptors, Estrogen; Substrate Specificity; Uterus | 1980 |
Regulation of sex-hormone-binding globulin production by endogenous estrogens in vitro.
Topics: 2-Methoxyestradiol; Carcinoma, Hepatocellular; Estradiol; Estriol; Estrogens; Estrone; Humans; Hydroxyestrones; Liver Neoplasms; Receptors, Estrogen; RNA, Messenger; Sex Hormone-Binding Globulin; Tumor Cells, Cultured | 1995 |
Metabolic deglucuronidation and demethylation of estrogen conjugates as a source of parent estrogens and catecholestrogen metabolites in Syrian hamster kidney, a target organ of estrogen-induced tumorigenesis.
Topics: 2-Methoxyestradiol; Animals; Cell Fractionation; Cricetinae; Estradiol; Estrogens, Conjugated (USP); Estrone; Glucuronidase; Kidney; Kidney Neoplasms; Liver; Lysosomes; Male; Mesocricetus; Methylation; Oxidoreductases, N-Demethylating | 1996 |
Effect of estradiol metabolites on prostacyclin synthesis in human endothelial cell cultures.
Topics: 2-Methoxyestradiol; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Estradiol; Estrone; Humans; Hydroxyestrones | 1999 |
Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Biological Transport, Active; Breast Neoplasms; Deoxyglucose; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Insulin; Kinetics; Paclitaxel; Tumor Cells, Cultured | 2000 |
Cytotoxicity of estradiol, equilin, equilenin, and their derivatives on Chinese hamster V79 cells.
Topics: 2-Methoxyestradiol; Animals; Cell Division; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Equilenin; Equilin; Estradiol; Estrone; Structure-Activity Relationship; Toxicity Tests | 2002 |
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Division; Cell Separation; Estradiol; Estrone; Female; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyestrones; Immunoblotting; Inhibitory Concentration 50; Male; Mitosis; Models, Chemical; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured | 2003 |
The demonstration of 2-methoxyoestrone and of 2-methoxyoestradiol in human pregnancy urine.
Topics: 2-Methoxyestradiol; Estradiol; Estradiol Congeners; Estrogens; Hydroxyestrones; Pregnancy | 1959 |
Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells.
Topics: 2-Methoxyestradiol; Activating Transcription Factor 2; Blotting, Western; Breast Neoplasms; Cyclic AMP Response Element-Binding Protein; Cyclin D1; DNA Replication; Enzyme Activation; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxyestrones; p38 Mitogen-Activated Protein Kinases; Transcription Factors | 2005 |
Synthesis of 2- and 17-substituted estrone analogs and their antiproliferative structure-activity relationships compared to 2-methoxyestradiol.
Topics: 2-Methoxyestradiol; Animals; Cell Line; Cell Proliferation; Estradiol; Estrone; Humans; Rats; Structure-Activity Relationship | 2009 |
Effect of flaxseed consumption on urinary levels of estrogen metabolites in postmenopausal women.
Topics: 2-Methoxyestradiol; Body Mass Index; Diet; Energy Intake; Estradiol; Estrogens; Female; Flax; Humans; Hydroxyestrones; Middle Aged; Postmenopause | 2010 |
A simple and convenient synthesis of 2-methoxyestradiol from estrone.
Topics: 2-Methoxyestradiol; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Estradiol; Estrone; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure | 2012 |
Estrogens and Their Genotoxic Metabolites Are Increased in Obese Prepubertal Girls.
Topics: 2-Methoxyestradiol; Case-Control Studies; Child; Estradiol; Estradiol Congeners; Estriol; Estrogens; Estrone; Female; Humans; Mutagens; Pediatric Obesity; Puberty; Thinness; Up-Regulation | 2015 |
Association of Active and Sedentary Behaviors with Postmenopausal Estrogen Metabolism.
Topics: 2-Methoxyestradiol; Accelerometry; Adult; Aged; Case-Control Studies; Estradiol; Estriol; Estrogens; Estrone; Exercise; Female; Humans; Middle Aged; Poland; Postmenopause; Sedentary Behavior | 2016 |
Estrogen metabolites in human corpus luteum physiology: differential effects on angiogenic activity.
Topics: 2-Methoxyestradiol; Biotransformation; Cell Line; Chorionic Gonadotropin; Corpus Luteum; Endothelial Cells; Estradiol; Estrogens; Estrone; Female; Granulosa Cells; Healthy Volunteers; Humans; Hydroxyestrones; Neovascularization, Physiologic; Progesterone; Vascular Endothelial Growth Factor A | 2016 |
Sitting, physical activity, and serum oestrogen metabolism in postmenopausal women: the Women's Health Initiative Observational Study.
Topics: 2-Methoxyestradiol; Aged; Estradiol; Estrogens; Estrone; Exercise; Female; Hormone Replacement Therapy; Humans; Middle Aged; Postmenopause; Posture; Sedentary Behavior; Surveys and Questionnaires | 2017 |
Novel PEP-PAN@PSF rods extraction of EDCs in environmental water, sediment, and fish homogenate followed by pre-column derivatization and UHPLC-MS/MS detection.
Topics: 2-Methoxyestradiol; Acrylic Resins; Animals; Chromatography, High Pressure Liquid; Environmental Monitoring; Estradiol; Estriol; Estrone; Ethinyl Estradiol; Fishes; Geologic Sediments; Polymers; Sulfones; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2020 |
Effect of Interaction between 17β-Estradiol, 2-Methoxyestradiol and 16α-Hydroxyestrone with Chromium (VI) on Ovary Cancer Line SKOV-3: Preliminary Study.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Line, Tumor; Cell Survival; Chromates; Chromium; Drug Antagonism; Drug Synergism; Estradiol; Female; Humans; Hydroxyestrones; Ovarian Neoplasms; Potassium Compounds | 2020 |
Regioselective synthesis, physicochemical properties and anticancer activity of 2-aminomethylated estrone derivatives.
Topics: 2-Methoxyestradiol; Amines; Antineoplastic Agents; Estradiol; Estrone | 2022 |