estrone has been researched along with 2-hydroxyestrone in 185 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (37.84) | 18.7374 |
| 1990's | 45 (24.32) | 18.2507 |
| 2000's | 44 (23.78) | 29.6817 |
| 2010's | 22 (11.89) | 24.3611 |
| 2020's | 4 (2.16) | 2.80 |
| Authors | Studies |
|---|---|
| Azzaoui, K; Diaz-Perez, MJ; Price, GB; Wainer, IW; Zannis-Hadjoupoulos, M | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Ball, P; Knuppen, R | 1 |
| Imoto, S | 1 |
| Kennedy, JA | 1 |
| Bradlow, HL; Michnovicz, JJ | 1 |
| Biswas, A; Chattoraj, SC; Dale, SL; Gajewski, A; Nuzzo, P | 1 |
| Higa, H | 1 |
| Lefebvre, J; Vandewalle, B | 1 |
| Bradlow, HL; Fishman, J; Haley, NJ; Hershcopf, RJ; Michnovicz, JJ | 1 |
| Kambegawa, A; Kimura, K; Nagaoka, M; Numazawa, M | 1 |
| Lamberts, SW; Verleun, T | 1 |
| Okatani, Y; Sagara, Y | 1 |
| Bonneterre, J; Lefebvre, J; Peyrat, JP; Vandewalle, B | 1 |
| Barnea, ER; Fakih, HN | 1 |
| Fishman, J; Okatani, Y | 2 |
| Pfeifer, RW; Si, EC; Yim, GK | 1 |
| Degen, GH; Eling, TE; McLachlan, JA; Sivarajah, K | 1 |
| Nambara, T; Ohkubo, T; Tsuchiko, F; Wakasawa, T | 1 |
| Gross, L; Melrose, P | 1 |
| Okatani, Y | 1 |
| Adeline, J; Janots, D; Kerdelhué, B; Ladosky, W; Lenoir, V; Scholler, R; Villard, MF | 1 |
| Bradlow, HL; Fishman, J; Hershcopf, RJ; Michnovicz, JJ; Naganuma, H | 1 |
| Naito, I; Nakano, M; Niki, E; Sugioka, K; Takekoshi, S | 1 |
| Abdalla, HI | 1 |
| Klibanski, A; Longcope, C; Ridgway, EC; Shupnik, MA | 1 |
| Patterson, RM; Pfeifer, RW | 1 |
| Brar, AK; Fink, G | 1 |
| Brennan, TF; Cecchini, DJ; Chattoraj, SC; Chobanian, AV; Edelin, KC; Wotiz, HH | 1 |
| Eisenberg, E | 1 |
| Jellinck, PH; Newcombe, AM | 1 |
| Barbieri, RL; Fishman, J; Morishita, H; Naftolin, F; Ryan, KJ; Todd, RB | 1 |
| Knuppen, R | 1 |
| Bates, L; Jellinck, PH; Shin, SH | 1 |
| Blake, CA; Rodriguez-Sierra, JF | 2 |
| Aten, RF; Eisenfeld, AJ; Hochberg, RB; MacLusky, NJ | 1 |
| Kono, S | 1 |
| Franks, S; MacLusky, NJ; Naftolin, F | 1 |
| Hersey, RM; Katzenellenbogen, BS; Weisz, J | 1 |
| Fishman, J | 2 |
| Brennan, TF; Cecchini, DJ; Chattoraj, SC; Gross, GL; Panda, SK; Schinfeld, JS | 1 |
| Fishman, J; Katayama, S | 2 |
| Ellendorff, F; Parvizi, N | 1 |
| Lipsett, MB; Loriaux, DL; Merriam, GR; Pfeiffer, DG | 1 |
| Brandon, DD; Fujino, T; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 1 |
| Martucci, CP | 1 |
| Collins, DC; Mitchell, D; Musey, PI; Russell, JB | 1 |
| Bradlow, HL; Fishman, J; Huh, MM; Schneider, J | 1 |
| Nambara, T; Shimada, K; Terashima, E; Yumura, Y | 1 |
| Brennan, TF; Cecchini, DJ; Chattoraj, SC; Edelin, KC; Fanous, AS; Panda, SK | 1 |
| Lamberts, SW; Oosterom, R | 1 |
| Araki, H; Hashino, M; Kawai, K; Nakayama, T; Ohno, H; Yanaihara, T | 1 |
| Barnea, ER; MacLusky, NJ; Naftolin, F | 1 |
| Abul-Hajj, YJ | 1 |
| Clarke, IJ; Findlay, JK | 1 |
| Franks, S; Goodyer, CG; Merriam, GR; Naftolin, F | 1 |
| Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 1 |
| Parvizi, N; Wuttke, W | 1 |
| Abel, MH; Kelly, RW | 1 |
| Brandon, DD; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 2 |
| Femino, A; Flood, C; Longcope, C; Williams, KI | 1 |
| Lamberts, SW; MacLeod, RM; Nagy, I; Uitterlinden, P | 1 |
| Jackson, GM; Rosenfeld, CR | 1 |
| DeGroff, V; Fishman, J; McEwen, BS; Paden, CM; Snyder, L | 1 |
| Haupt, O; Hoppen, HO; Knuppen, R | 1 |
| Davis, PG; Jellinck, PH; Kamel, F; Krey, L; Luine, V; McEwen, BS; Parsons, B; Roy, EJ | 1 |
| Nambara, T; Shimada, K; Tanaka, T | 1 |
| Butt, WR; Franks, S; Jacobs, HS; Lightman, SL; Lynch, SS; MaClusky, NJ; Naftolin, F | 1 |
| Kono, S; Maruta, S; Mori, I; Nagasako, S | 1 |
| Fishman, J; Tulchinsky, D | 1 |
| Brandon, DD; Davis, SE; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 1 |
| Bradlow, HL; Klug, TL; Sepkovic, DW | 1 |
| Haji, M; Kobayashi, K; Nawata, H; Takayanagi, R; Taniguchi, S; Umeda, F; Yanase, T | 1 |
| Bradlow, HL; Fishman, J; Osborne, MP; Telang, NT | 1 |
| Bui, QD; Liehr, JG; Weisz, J; Zhu, BT | 1 |
| Bradlow, HL; Levy, I; Michnovicz, J; Murtezani, S; Osborne, MP; Sepkovic, DW | 1 |
| Fottrell, PF; McGuinness, BJ; Power, MJ | 1 |
| Galbraith, RA; Michnovicz, JJ | 1 |
| Bradlow, HL; Fishman, J; Gong, L; Hankinson, SE; Ho, G; Osborne, MP; Sepkovic, DW | 1 |
| Del Zotto, H; Etchegoyen, GS | 1 |
| Bradlow, HL; Davis, DL; Lin, G; Sepkovic, D; Tiwari, R | 1 |
| Clausen, J; Kall, MA; Vang, O | 2 |
| Goto, J; Iwasaki, R; Matsuki, Y; Nambara, T; Suzuki, E | 1 |
| Bradlow, HL; Buhari, AM; Kuller, LH; Meilahn, EN; Pasagian-Macaulay, A; Sepkovic, DW; Simkin-Silverman, L; Wing, RR | 1 |
| Chen, C; Daling, JR; Malone, KE; Prunty, J | 1 |
| Bradlow, HL; Osborne, MP; Sepkovic, DW; Telang, NT | 1 |
| Chung, BC; Huh, KB; Kim, KR; Kwon, SH; Lee, EJ; Lee, HC; Lee, JH; Lim, SK; Won, YJ | 1 |
| Gentzschein, E; London, S; Paganini-Hill, A; Pike, MC; Ross, RK; Stanczyk, FZ; Ursin, G | 2 |
| Adlercreutz, H; Bradlow, HL; Donaldson, JL; Falk, RT; Fears, TR; Fillmore, CM; Gail, MH; Hoover, RN; Kiuru, P; Rossi, SC; Sepkovic, D; Siiteri, PK; Vaught, JB; Wahala, K; Ziegler, RG | 1 |
| Bradlow, HL; Chang, CJ; Hu, XP; Kabat, GC; Khalil, A; Rosenblatt, R; Sepkovie, DW; Sparano, JA | 1 |
| Lippert, TH; Mueck, AO; Seeger, H | 5 |
| McDougal, A; Safe, S | 1 |
| Service, RF | 1 |
| Michnovicz, JJ | 1 |
| Evans, GL; Gibson, KJ; Malone, P; Turner, RT; Westerlind, KC | 1 |
| Foo, SC; Ho, GH; Ji, CY; Luo, XW; Ng, EH | 1 |
| Allen, DS; Bradlow, HL; De Stavola, B; Fentiman, I; Kuller, LH; Meilahn, EN; Sepkovic, DW | 1 |
| Cheng, Z; Coffman, BL; Green, MD; King, CD; Mackenzie, PI; Mojarrabi, B; Rios, GR; Tephly, TR | 1 |
| Gupta, M; McDougal, A; Safe, S | 1 |
| Bradlow, HL; Ganguly, S; Garbers, SV; Garte, SJ; Osborne, MP; Sepkovic, DW; Taioli, E; Trachman, J | 1 |
| Gibson, KJ; Westerlind, KC; Wolfe, P | 1 |
| Bradlow, HL; Kabat, GC | 1 |
| Di, A; Huang, M; Shan, H; Wu, X; Xu, R | 1 |
| Carruba, G; Castagnetta, LA | 1 |
| Anderson, KG; Chen, Z; Dunning, LM; Holtzman, JL; Parrish, RS; Zheng, W | 1 |
| Barbieri, RL; Bradlow, HL; Hankinson, SE; Manson, JE; Michaud, DS; Sepkovic, DW; Spiegelman, D | 1 |
| Adlercreutz, H; Bradlow, HL; Donaldson, J; Falk, RT; Fears, TR; Migella, A; Rossi, SC; Sepkovic, DW; Ziegler, RG | 1 |
| Anderson, KE; Cree, M; Grady, JJ; Josyula, S; Lu, LJ; Nagamani, M | 1 |
| Robinson, JA; Spelsberg, TC; Turner, RT; Waters, KM | 1 |
| Gruber, DM; Huber, JC | 1 |
| Bell, MC; Bradlow, HL; Crowley-Nowick, P; Howell, P; Mathis, JM; Mayeaux, EJ; Schmidt-Grimminger, D; Sepkovic, DW; Tucker, A; Turbat-Herrera, EA | 1 |
| Fowke, JH; Hebert, JR; Longcope, C | 1 |
| Gardner, F; Smith, SJ; Spierto, FW | 1 |
| Shibutani, S; Suzuki, N; Terashima, I | 1 |
| Bradlow, HL; Jernström, H; Narod, SA; Vesprini, D | 1 |
| Barry, S; Cantin, AM; Jay-Gerin, JP; Kocsis-Bédard, S; Lemay, R; Paquette, B | 1 |
| Bradlow, HL; De Stavola, B; dos Santos Silva, I; Linos, A; Linos, D; Riza, E; Sepkovic, DW | 1 |
| Chattoraj, SC; Panda, SK | 1 |
| Lotinun, S; Turner, RT; Westerlind, KC | 1 |
| Beppu, M; Ebihara, K; Izumi, T; Kishida, T; Nashiki, K | 1 |
| Barrett, JC; Tsutsui, T; Yagi, E | 1 |
| Gräser, T; Lippert, TH; Mueck, AO; Oettel, M; Seeger, H | 1 |
| Bernstein, L; Gentzschein, E; London, S; Pike, MC; Stanczyk, FZ; Tseng, CC; Ursin, G; Yang, D | 1 |
| Keefer, LK; Saavedra, JE; Waterhouse, DJ; Xu, X; Ziegler, RG | 1 |
| Almario, RU; Gregory, L; Kasim-Karakas, SE; Lasley, BL; Todd, H; Wong, R | 1 |
| Kastango, KB; Kirshner, MA; Klug, TL; Pollock, BG; Thompson, DS | 1 |
| Bradlow, HL; Jernström, H; Klug, TL; Narod, SA; Sepkovic, DW | 1 |
| Alvarez-Vasquez, RB; Axelrod, D; Bradlow, HL; Frenkel, K; Newman, MC; Sepkovic, DW; Zumoff, B | 1 |
| COX, RI; FISHMAN, J; GALLAGHER, TF | 1 |
| Bauer, DC; Cauley, JA; Cummings, SR; Danielson, ME; Kuller, LH; Ljung, BM; Zmuda, JM | 1 |
| Mueck, AO; Seeger, H; Wallwiener, D | 1 |
| Bjeldanes, LF; Bradlow, HL; Dalessandri, KM; Firestone, GL; Fitch, MD | 1 |
| Campbell, KL; Courneya, KS; Friedenreich, CM; Harber, VJ; Westerlind, KC | 1 |
| Bradlow, HL; Garte, S; Paracchini, V; Pedotti, P; Raimondi, S; Sepkovic, DW; Taioli, E | 1 |
| Jou, HJ; Lu, SC; Wang, TA; Wang, TF; Wu, WH | 1 |
| Boulware, RJ; Cunningham, JE; Fowke, JH; Hebert, JR; Hurley, TG; Kanwat, CP; Nitcheva, D; Sepkovic, DW; Teas, J | 1 |
| Bradlow, HL; Britton, JA; Gammon, MD; Kabat, GC; Neugut, AI; O'Leary, ES; Sepkovic, DW; Teitelbaum, SL; Terry, MB | 1 |
| Crawford, S; Gold, EB; Lasley, B; McConnell, DS; Randolph, JF; Sowers, MR; Wilkin, MK | 1 |
| Han, GZ; Jiang, XR; Shim, JY; Wen, Y; Zhu, BT | 1 |
| Buyuktur, AG; Hochberg, M; Jamadar, DA; Jannausch, M; McConnell, D; Sowers, MR | 1 |
| Bågeman, E; Ingvar, C; Jernström, H; Klug, TL; Rose, C | 1 |
| Hsu, IP; Huang, CW; Jou, HJ; Wang, TA; Wu, WH | 1 |
| Brook, R; Crawford, S; Gold, EB; Jannausch, ML; Lasley, B; McConnell, D; Randolph, JF; Sowers, M | 1 |
| Al-Hendy, A; Fouad, H; Garfield, RE; Harirah, HM; Salama, SA; Shi, L; Shi, SQ; Wentz, MJ | 1 |
| Grady, JJ | 1 |
| Byers, T; Lezotte, D; Risendal, B; Wacker, M; Westerlind, K | 1 |
| Ahrendt, G; Garte, S; Im, A; Lloyd, S; Ragin, C; Taioli, E; Vogel, VG | 1 |
| Barba, M; Blandino, G; Gallucci, M; Grioni, S; Lauria, R; Malorni, L; Muti, P; Schünemann, HJ; Sperati, F; Stranges, S; Westerlind, KC; Yang, L | 1 |
| Bertone-Johnson, ER; Bigelow, C; Heersink, J; Kurzer, MS; Puleo, E; Sabelawski, S; Sturgeon, SR; Volpe, SL; Wahala, K | 1 |
| Cai, D; Chen, Y; Gao, W; Li, Y; Liu, B; Wen, X; Zeng, C | 1 |
| Cho, SH; Choi, MH; Chung, BC; Lee, EJ; Moon, JY | 1 |
| Afanasyeva, Y; Arslan, AA; Berrino, F; Hallmans, G; Idahl, A; Koenig, KL; Krogh, V; Lenner, P; Liu, M; Lukanova, A; Lundin, E; Muti, P; Ohlson, N; Shore, RE; Sieri, S; Toniolo, P; Zeleniuch-Jacquotte, A | 1 |
| Bradlow, HL; Li, G; Sepkovic, DW; Telang, NT; Wong, GY | 1 |
| Conroy, SM; Franke, AA; Isaki, M; Maskarinec, G; Morimoto, Y; Nordt, FJ; Pagano, IS | 1 |
| Custer, L; Franke, AA; Heak, S; Maskarinec, G; Morimoto, Y | 1 |
| Custer, L; Franke, AA; Heak, S; Isaki, M; Maskarinec, G; Morimoto, Y; Steinbrecher, A | 1 |
| Bazzan, AJ; Newberg, AB; Zabrecky, GP | 1 |
| Bradlow, HL; Li, G; Sepkovic, D; Telang, N; Wong, GY | 1 |
| Afanasyeva, Y; Arslan, AA; Chen, Y; Hallmans, G; Koenig, KL; Lenner, P; Lundin, E; Shore, RE; Toniolo, P; Zeleniuch-Jacquotte, A | 1 |
| Huober, J; Mueck, AO; Ruan, X; Seeger, H; Wallwiener, D | 1 |
| Cassorla, F; Codner, E; Iñiguez, G; Lopez, P; Martínez, D; Merino, PM; Perez-Bravo, F | 1 |
| Cai, DZ; Gao, WL; Li, YZ; Song, YC; Wu, B; Wu, LS; Zi, JH | 1 |
| Bradlow, HL; Kotsopoulos, J; Llacuachaqui, M; Narod, SA; Nikitina, D; Sepkovic, D | 1 |
| Godínez Martínez, EY; Juárez González, AR; Lemus Bravo, AE; Rodríguez Ventura, AL; Sámano, R; Santillán Ballesteros, R; Tolentino Dolores, M | 1 |
| Fuhrman, BJ; Matthews, CE; Moore, SC; Ziegler, RG | 1 |
| Dikshit, A; Eilati, E; Gao, C; Gomes Filho, MA; Hales, DB; Klug, T; McGee, S; Small, C | 1 |
| Gheldiu, AM; Loghin, F; Popa, DS; Vlase, L | 1 |
| Brinton, LA; Chicoine, RE; Falk, RT; Figueroa, JD; Geller, BM; Gierach, GL; Hewitt, SM; Horne, HN; Khodr, ZG; Linville, L; Oh, H; Palakal, M; Papathomas, D; Patel, DA; Pfeiffer, RM; Shepherd, JA; Sherman, ME; Vacek, PM; Veenstra, T; Weaver, DL; Xiang, J; Xu, X | 1 |
| Altbach, M; Chalasani, P; Chow, HHS; Galons, JP; Huang, C; Maskarinec, G; Roe, DJ; Stopeck, A; Strom, MB; Thompson, PA; Thomson, CA; Wertheim, BC | 1 |
| Boucher, BA; Chang, VC; Cotterchio, M; Jenkins, DJA; McCann, SE; Mirea, L; Thompson, LU | 1 |
| Ji, J; Sun, J; Sun, X; Xu, S; Zhang, Y | 1 |
| Braundmeier-Fleming, A; Bremer, P; Brown, V; Cregger, M; Diaz-Sylvester, P; Groesch, K; Le, N; Loret de Mola, J; Nguyen, L; Wilson, T | 1 |
| Ge, J; Ge, W; He, J; Wang, M; Yang, N; Zhang, X; Zhu, H | 1 |
| Brix, J; Gahler, RJ; Gerry, A; Glover, M; Green, T; Li, K; Newman, M; Reil, J; Schauch, M; See, J; Wood, S | 1 |
10 review(s) available for estrone and 2-hydroxyestrone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Pathophysiology of hot flushes.
Topics: Catecholamines; Climacteric; Cytochrome P-450 CYP1A1; Endorphins; Estrogens; Female; Humans; Hydroxyestrones; Male; Steroid Hydroxylases; Vasomotor System | 1985 |
Toward an understanding of reproductive function in anorexia nervosa.
Topics: Adipose Tissue; Adolescent; Adult; Amenorrhea; Animals; Anorexia Nervosa; Body Weight; Circadian Rhythm; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydroxyestrones; Hypothalamus; Luteinizing Hormone; Menstruation; Neurotransmitter Agents; Ovulation; Puberty; Reproduction | 1981 |
2-hydroxyestrone: the 'good' estrogen.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Hydroxylation | 1996 |
Conjugated estrogens--the natural SERMs.
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Cardiovascular Diseases; Dihydrotestosterone; Equilin; Estradiol; Estradiol Congeners; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxyestrones; Osteoporosis; Progesterone; Selective Estrogen Receptor Modulators; Testosterone; Thyroxine; Triiodothyronine | 1999 |
Estradiol metabolism and malignant disease.
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Estradiol; Estriol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Molecular Structure; Neoplasms | 2002 |
[Estrogen-dependent neoplasia - what is the significance of estradiol metabolites].
Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Breast Neoplasms; Estradiol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Male; Neovascularization, Pathologic; Neovascularization, Physiologic; Postmenopause; Prostatic Neoplasms | 2003 |
Analysis of change.
Topics: Analysis of Variance; Animals; Data Interpretation, Statistical; Humans; Hydroxyestrones; Isoflavones; Longitudinal Studies; Research Design; Soybean Proteins | 2007 |
Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis.
Topics: Aged; Case-Control Studies; Chromatography, Liquid; Estrogens; Humans; Hydroxyestrones; Male; Mass Spectrometry; Middle Aged; Prostatic Neoplasms; Risk Factors | 2009 |
Epidemiologic studies of estrogen metabolism and breast cancer.
Topics: Breast Neoplasms; Chromatography, Liquid; Epidemiologic Studies; Estrogens; Female; Humans; Hydroxyestrones; Postmenopause; Premenopause; Prospective Studies; Risk Factors; Tandem Mass Spectrometry | 2015 |
18 trial(s) available for estrone and 2-hydroxyestrone
| Article | Year |
|---|---|
Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism.
Topics: Adult; Caffeine; Chlorzoxazone; Diet; Female; Humans; Hydroxyestrones; Male; Reference Values; Vegetables | 1996 |
Urinary markers of estrogen metabolism 2- and 16 alpha-hydroxylation in premenopausal women.
Topics: Adult; Body Weight; Female; Humans; Hydroxyestrones; Hydroxylation; Immunoassay; Middle Aged; Premenopause; Reference Values; Reproducibility of Results; Risk Factors; Steroid 16-alpha-Hydroxylase; Time Factors | 1996 |
Effects of dietary broccoli on human drug metabolising activity.
Topics: Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2E1; Diet; Glutathione Transferase; Humans; Hydroxyestrones; Intestines; Liver; Lymphocytes; Vegetables | 1997 |
Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol.
Topics: Administration, Oral; Adult; Antioxidants; Cohort Studies; Estradiol; Estriol; Estrogen Antagonists; Female; Humans; Hydroxyestrones; Hydroxylation; Indoles; Middle Aged; Obesity; Premenopause | 1998 |
Estradiol metabolism during oral and transdermal estradiol replacement therapy in postmenopausal women.
Topics: Administration, Cutaneous; Administration, Oral; Estradiol; Estrone; Female; Hormone Replacement Therapy; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Radioimmunoassay | 1998 |
Role of estradiol metabolism and CYP1A1 polymorphisms in breast cancer risk.
Topics: Adult; Black People; Breast Neoplasms; Case-Control Studies; Cytochrome P-450 CYP1A1; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Genotype; Humans; Hydroxyestrones; Indoles; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; RNA, Messenger; White People | 1999 |
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.
Topics: Administration, Oral; Anticarcinogenic Agents; DNA, Viral; Dose-Response Relationship, Drug; Female; Humans; Hydroxyestrones; Indoles; Papillomaviridae; Papillomavirus Infections; Placebos; Polymerase Chain Reaction; Precancerous Conditions; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2000 |
Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women.
Topics: Aged; Analysis of Variance; Anticarcinogenic Agents; Brassica; Breast Neoplasms; Estrogens; Female; Humans; Hydroxyestrones; Least-Squares Analysis; Middle Aged; Phytotherapy; Postmenopause | 2000 |
Effect of norethisterone acetate on estrogen metabolism in postmenopausal women.
Topics: Anticarcinogenic Agents; Contraceptives, Oral, Synthetic; Estradiol; Estrogen Replacement Therapy; Female; Humans; Hydroxyestrones; Male; Middle Aged; Norethindrone; Postmenopause | 2000 |
Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer.
Topics: Aged; Breast Neoplasms; Dietary Supplements; Estradiol; Estriol; Female; Hormones; Humans; Hydrocortisone; Hydroxyestrones; Indoles; Middle Aged; Neoplasm Staging; Postmenopause | 2004 |
Effects of docosahexaenoic acid supplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in postmenopausal vegetarian women.
Topics: alpha-Tocopherol; Biomarkers; Diet, Vegetarian; Dietary Supplements; Docosahexaenoic Acids; Estrogens; Eukaryota; F2-Isoprostanes; Female; Humans; Hydroxyestrones; Lipids; Middle Aged; Oxidative Stress; Postmenopause; Single-Blind Method | 2006 |
The effects of soygerm extracts on blood lipoproteins, antioxidative capacity and urinary estrogen metabolites in postmenopausal women on hormone therapy.
Topics: Antioxidants; Cholesterol, HDL; Cholesterol, LDL; Copper; Estrogen Replacement Therapy; Estrogens; Female; Glycine max; Humans; Hydroxyestrones; Isoflavones; Lipoproteins, LDL; Middle Aged; Oxidation-Reduction; Pilot Projects; Plant Extracts; Postmenopause; Taiwan; Thiobarbituric Acid Reactive Substances; Triglycerides | 2007 |
Urinary estrogen metabolites during a randomized soy trial.
Topics: Adult; China; Cross-Over Studies; Diet; Equol; Estrogens; Ethnicity; Female; Flavonoids; Hawaii; Humans; Hydroxyestrones; Isoflavones; Japan; Korea; Middle Aged; Philippines; Premenopause; Soy Foods; White People | 2012 |
The relation of urinary estrogen metabolites with mammographic densities in premenopausal women.
Topics: Adult; Asian People; Breast; Breast Neoplasms; Cell Count; Estrogens; Female; Humans; Hydroxyestrones; Mammography; Middle Aged; Premenopause; Progesterone; Risk Assessment; Testosterone | 2012 |
Urinary estrogen metabolites in two soy trials with premenopausal women.
Topics: Adult; Chromatography, Liquid; Cross-Over Studies; Diet; Estrogens; Female; Humans; Hydroxyestrones; Isoflavones; Mass Spectrometry; Premenopause; Regression Analysis; Soy Foods | 2012 |
A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Female; Humans; Hydroxyestrones; Indoles; Mammography; Middle Aged; Sex Hormone-Binding Globulin; Tamoxifen; Time Factors; Treatment Outcome | 2017 |
Effect of Dietary Flaxseed Intake on Circulating Sex Hormone Levels among Postmenopausal Women: A Randomized Controlled Intervention Trial.
Topics: Breast Neoplasms; Canada; Diet; Female; Flax; Gonadal Steroid Hormones; Humans; Hydroxyestrones; Lignans; Middle Aged; Postmenopause; Prolactin | 2019 |
A randomized, double-blind, placebo-controlled, cross-over trial to evaluate the effect of EstroSense
Topics: Biomarkers; Breast Neoplasms; Cross-Over Studies; Estrogens; Female; Humans; Hydroxyestrones | 2023 |
157 other study(ies) available for estrone and 2-hydroxyestrone
| Article | Year |
|---|---|
Effect of steroids on DNA synthesis in an in vitro replication system: initial quantitative structure-activity relationship studies and construction of a non-estrogen receptor pharmacophore.
Topics: DNA; DNA Replication; HeLa Cells; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptors, Steroid; Steroids; Structure-Activity Relationship | 1998 |
Formation of 2- and 4-hydroxyestrogens by brain, pituitary, and liver of the human fetus.
Topics: Brain; Estradiol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Hydroxylation; Liver; Pituitary Gland | 1978 |
[Biological effect of estrogen metabolites in human breast cancer].
Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; Receptors, Estrogen; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tumor Cells, Cultured | 1992 |
Effect of catechol oestrogens on extraneuronal metabolism of noradrenaline by rabbit uterine endometrium and myometrium.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase Inhibitors; Endometrium; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Methylation; Monoamine Oxidase Inhibitors; Myometrium; Norepinephrine; Rabbits; Tritium | 1991 |
Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol.
Topics: Adult; Antioxidants; Body Mass Index; Body Water; Estradiol; Estriol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Indoles; Male; Tritium | 1991 |
Temporal relationships among the excretory patterns of 2-hydroxyestrone, estrone, estradiol, and progesterone during pregnancy in the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Estradiol; Estrone; Female; Hydroxyestrones; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Inbred Strains; Time Factors | 1991 |
[Effects of catecholestrogen and catecholestrogen 2-monomethyl ether on serum lipids and lipoproteins in rats].
Topics: Animals; Cholesterol; Cholesterol, HDL; Diet; Estradiol; Estriol; Female; Hydroxyestrones; Hypercholesterolemia; Ovariectomy; Rats; Rats, Inbred Strains; Triglycerides | 1990 |
Opposite effects of estrogen and catecholestrogen on hormone-sensitive breast cancer cell growth and differentiation.
Topics: Breast Neoplasms; Cells, Cultured; Estradiol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Receptors, Progesterone; Receptors, Transferrin | 1989 |
Cigarette smoking alters hepatic estrogen metabolism in men: implications for atherosclerosis.
Topics: Adult; Arteriosclerosis; Estriol; Estrogens; Humans; Hydroxyestrones; Hydroxylation; Liver; Male; Middle Aged; Smoking | 1989 |
Radioimmunoassay of 2-hydroxyesterone using antisera raised against antigenic complexes obtained by convenient methods.
Topics: Adult; Animals; Cross Reactions; Estrone; Female; Humans; Hydroxyestrones; Male; Rabbits; Radioimmunoassay | 1989 |
Differences in the mechanism of the inhibitory actions of catecholestrogens, tamoxifen and high concentrations of estrogens on prolactin release by cultured rat pituitary tumor cells.
Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens, Catechol; Female; Hydroxyestrones; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred BUF; Secretory Rate; Tamoxifen; Tumor Cells, Cultured | 1987 |
[Mechanism of the suppressive effect of catechol estrogen on the preovulatory LH surge].
Topics: Animals; Estradiol; Estrogens, Catechol; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Hydroxyestrones; Luteinizing Hormone; Median Eminence; Rats; Rats, Inbred Strains | 1987 |
Catecholestrogen binding sites in breast cancer.
Topics: Binding Sites; Breast Neoplasms; Catechol O-Methyltransferase; Cell Fractionation; Chromatography, High Pressure Liquid; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Receptors, Estrogen; Structure-Activity Relationship; Time Factors; Tritium | 1985 |
The role of catecholestrogens in placental steroidogenesis.
Topics: Estradiol; Estrone; Female; Humans; Hydroxyestrones; In Vitro Techniques; Phenoxybenzamine; Placenta; Pregnancy; Progesterone; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Steroids | 1985 |
Effect of catechol estrogens on the preovulatory content of luteinizing hormone-releasing hormone in the median eminence of the rat.
Topics: Animals; Estradiol; Estrogens, Catechol; Estrus; Female; Gonadotropin-Releasing Hormone; Hydroxyestrones; Luteinizing Hormone; Median Eminence; Proestrus; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Iodoacetic acid and related sulfhydryl reagents fail to inhibit cell-cell communication: mechanisms of immunotoxicity in vitro.
Topics: Agglutination; Animals; Cell Communication; Dose-Response Relationship, Drug; Estrone; Female; Hydroquinones; Hydroxyestrones; Indoleacetic Acids; Lymphocyte Activation; Mice; Mice, Inbred Strains; Microtubules; Monophenol Monooxygenase; Phytohemagglutinins | 1987 |
Cooxidation of steroidal and non-steroidal estrogens by purified prostaglandin synthase results in a stimulation of prostaglandin formation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diethylstilbestrol; Estradiol; Estrogens; Estrone; Hydroxyestrones; Male; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Seminal Vesicles; Sheep | 1987 |
Preparation and antigenic properties of 2-hydroxyestrone-[C-15]-bovine serum albumin conjugate.
Topics: Animals; Antigens; Cattle; Chemical Phenomena; Chemistry; Estrone; Hydroxyestrones; Serum Albumin, Bovine | 1988 |
Steroid effects on the secretory modalities of gonadotropin-releasing hormone release.
Topics: Animals; Brain; Dihydrotestosterone; Estradiol; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Hydroxyestrones; Male; Neurons; Progesterone; Rats; Rats, Inbred Strains; Testosterone | 1987 |
[Study on the central action of catecholestrogen: effect of 2-hydroxyestrogens on the preovulatory LH surge].
Topics: Animals; Estradiol; Estrone; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Hydroxyestrones; Luteinizing Hormone; Ovariectomy; Proestrus; Rats; Rats, Inbred Strains | 1986 |
Inhibition of the preovulatory LH surge after a catecholestrogen (2-hydroxyestrone) antiserum injection in the third ventricle of cycling female rats.
Topics: Animals; Brain Mapping; Estrone; Female; Hydroxyestrones; Hypothalamo-Hypophyseal System; Immune Sera; Injections, Intraventricular; Luteinizing Hormone; Ovulation; Rats; Rats, Inbred Strains | 1987 |
Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking.
Topics: Adult; Estradiol; Estrogens; Female; Humans; Hydroxyestrones; Hydroxylation; Menopause; Menstrual Cycle; Smoking; Steroid 16-alpha-Hydroxylase | 1986 |
Novel and potent biological antioxidants on membrane phospholipid peroxidation: 2-hydroxy estrone and 2-hydroxy estradiol.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Doxorubicin; Estradiol; Estriol; Estrone; Ferric Compounds; Hydroxyestrones; Kinetics; Lipid Peroxides; Liposomes; Microsomes, Liver; Oxygen Consumption; Phospholipids; Rats; Vitamin E | 1987 |
Catecholestrogen regulation of prolactin synthesis in pituitary cell culture.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Hydroxyestrones; Nucleic Acid Hybridization; Pituitary Gland, Anterior; Prolactin; Rats; RNA, Messenger; Time Factors | 1985 |
Modulation of nonspecific cell-mediated growth inhibition by estrogen metabolites.
Topics: Animals; Cell Division; Cell Membrane; Cytotoxicity, Immunologic; Estradiol; Estrogens; Female; Hydroxyestrones; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Activation; Lymphoma; Mice; Phytohemagglutinins; Rats | 1985 |
Effects of acute administration of 2-hydroxylated metabolites of oestrogens on LH and prolactin secretion in male and female prepubertal rats.
Topics: Animals; Estradiol; Estrogens, Catechol; Female; Gonadotropins, Equine; Hydroxyestrones; Luteinizing Hormone; Male; Organ Size; Ovary; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Sexual Maturation; Uterus | 1984 |
The absence of a catechol estrogen effect on blood pressure in the male rat.
Topics: Animals; Blood Pressure; Catechol O-Methyltransferase Inhibitors; Drug Implants; Estradiol; Estrogens, Catechol; Hydroxyestrones; Male; Rats | 1983 |
Effect of catechol estrogens and estriol on the induction of uterine peroxidase.
Topics: Animals; Catechols; Enzyme Induction; Estradiol; Estriol; Estrogens; Estrogens, Catechol; Female; Hydroxyestrones; Peroxidases; Rats; Structure-Activity Relationship; Uterus | 1980 |
Response of serum prolactin to catechol estrogen in the immature rat.
Topics: Animals; Catechol O-Methyltransferase; Catechols; Estradiol; Estrogens; Estrogens, Catechol; Hydroxyestrones; Luteinizing Hormone; Male; Prolactin; Rats | 1980 |
Mediators of feedback message: estrogens and/or catechol-estrogens?
Topics: Animals; Catechols; Estrogens; Estrogens, Catechol; Feedback; Female; Gonadotropins, Pituitary; Humans; Hydroxyestrones; Hypothalamo-Hypophyseal System; Menstruation; Ovary; Rats | 1981 |
Temporal and other effects of catechol estrogens on prolactin secretion in the rat.
Topics: Animals; Drug Implants; Drug Interactions; Estradiol; Estrogens, Catechol; Hydroxyestrones; Kinetics; Male; Prolactin; Rats; Rats, Inbred Strains | 1981 |
Catecholestrogens and release of anterior pituitary gland hormones. I. Luteinizing hormone.
Topics: Animals; Estradiol; Estrogens, Catechol; Estrone; Feedback; Female; Hydroxyestrones; Luteinizing Hormone; Male; Rats; Rats, Inbred Strains; Sexual Maturation | 1982 |
Catecholestrogens and release of anterior pituitary gland hormones. II. Prolactin.
Topics: Animals; Estradiol; Estrogens, Catechol; Estrone; Female; Hydroxyestrones; Male; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sexual Maturation | 1982 |
Separation of steroidal estrogens and their major unconjugated metabolites by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Estradiol; Estrogens; Estrogens, Catechol; Hydroxyestrones | 1982 |
[Specific radioimmunoassay and physiological significance of unconjugated 2-hydroxyestrone and 2-hydroxyestradiol-17 beta in human blood (author's transl)].
Topics: Adult; Cross Reactions; Estradiol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Male; Pregnancy; Radioimmunoassay | 1982 |
Comparative pharmacology of oestrogens and catechol oestrogens: actions on the immature rat uterus in vivo and in vitro.
Topics: Animals; Estradiol; Estrogens; Estrogens, Catechol; Estrone; Female; Hydroxyestrones; Organ Size; Rats; Rats, Inbred Strains; Sexual Maturation; Uterus | 1982 |
Estrogenic potency, receptor interactions, and metabolism of catechol estrogens in the immature rat uterus in vitro.
Topics: Animals; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Methylation; Propiophenones; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Estrogen; Subcellular Fractions; Tissue Distribution; Uterus | 1982 |
Catechol estrogens and pituitary function.
Topics: Animals; Castration; Estradiol; Estrogens, Catechol; Female; Gonadotropins, Pituitary; Hydroxyestrones; Male; Pituitary Gland; Rats; Rats, Inbred Strains | 1982 |
Urinary catechol estrogens in cycles stimulated by human menopausal gonadotropin.
Topics: Estradiol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Infertility, Female; Menotropins; Ovulation Induction; Radioimmunoassay | 1983 |
Inhibition of phasic but not tonic pituitary secretion by 2-hydroxyoestrone in the rat: evidence of action as an oestrogen antagonist.
Topics: Animals; Castration; Depression, Chemical; Estradiol; Estrogen Antagonists; Estrogens, Catechol; Estrone; Female; Hydroxyestrones; Luteinizing Hormone; Pituitary Gland; Pregnancy; Proestrus; Prolactin; Rats; Rats, Inbred Strains; Secretory Rate; Time Factors | 1983 |
Catecholestrogens in the brain: neuroendocrine integration.
Topics: Animals; Brain; Castration; Dopamine; Epinephrine; Estradiol; Estrogens, Catechol; Hydroxyestrones; Hypothalamus; Luteinizing Hormone; Male; Norepinephrine; Preoptic Area; Swine; Swine, Miniature | 1983 |
Catechol estrogens and the control of gonadotropin and prolactin secretion in man.
Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Estrogens, Catechol; Estrone; Female; Follicle Stimulating Hormone; Follicular Phase; Humans; Hydroxyestrones; Kinetics; Luteinizing Hormone; Male; Prolactin; Rats; Reference Values | 1983 |
Radioimmunoassay and metabolic clearance rate of catecholestrogens, 2-hydroxyestrone and 2-hydroxyestradiol in man.
Topics: Adult; Blood Pressure; Child; Child, Preschool; Estradiol; Estrogens; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Kinetics; Male; Menstruation; Metabolic Clearance Rate; Pre-Eclampsia; Pregnancy; Radioimmunoassay | 1983 |
The role of 2-methoxyestrone in estrogen action.
Topics: Aging; Animals; Animals, Newborn; Brain; Estrogens; Estrogens, Catechol; Estrone; Female; Hydroxyestrones; Liver; Male; Rats; Receptors, Estrogen; Structure-Activity Relationship; Tissue Distribution; Uterine Contraction; Uterus | 1983 |
The relationship of exercise to anovulatory cycles in female athletes: hormonal and physical characteristics.
Topics: Adolescent; Adult; Anovulation; beta-Endorphin; Catecholamines; Endorphins; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydroxyestrones; Luteinizing Hormone; Physical Exertion; Prolactin; Sports Medicine | 1984 |
Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Estradiol; Estrogen Antagonists; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Kinetics; Receptors, Estrogen | 1984 |
In vitro metabolic conjugation of catechol estrogens.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Estrogens, Catechol; Estrogens, Conjugated (USP); Estrone; Female; Glucuronates; Guaiacol; Guinea Pigs; Humans; Hydroxyestrones; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Sulfates | 1984 |
Suppression of the preovulatory luteinizing hormone surge in the rat by 2-hydroxyestrone: relationship to endogenous estradiol levels.
Topics: Animals; Castration; Estradiol; Estrone; Estrus; Female; Gonadotropin-Releasing Hormone; Hydroxyestrones; Luteinizing Hormone; Pregnancy; Proestrus; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Radioimmunoassay of 2-hydroxyestrone in plasma during the estrous cycle of the rat: interrelationships with estradiol, progesterone, and the gonadotropins.
Topics: Animals; Estradiol; Estrone; Estrus; Female; Follicle Stimulating Hormone; Hydroxyestrones; Luteinizing Hormone; Pregnancy; Progesterone; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains | 1983 |
Absence of a suppressive effect of 2-hydroxyestrone on hyperprolactinemia in patients with prolactinomas before and after estradiol administration.
Topics: Adult; Aged; Craniopharyngioma; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Hydroxyestrones; Hypopituitarism; Kinetics; Luteinizing Hormone; Male; Middle Aged; Pituitary Neoplasms; Prolactin | 1983 |
[Changes in plasma 2-hydroxyestrone levels in pubertal females and correlation with sex hormones].
Topics: Adolescent; Age Factors; Ascorbic Acid; Child; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Hydroxyestrones; Luteinizing Hormone; Prolactin; Puberty; Radioimmunoassay | 1984 |
Kinetics of catechol estrogen-estrogen receptor dissociation: a possible factor underlying differences in catechol estrogen biological activity.
Topics: Animals; Binding, Competitive; Cell Nucleus; Cytosol; Estradiol; Estrone; Female; Hydroxyestrones; Kinetics; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus | 1983 |
Binding of catechol estrogens to the estrogen receptor of dimethylbenz(A) anthracene induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytosol; Estradiol; Estriol; Estrogens; Female; Hydroxyestrones; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Uterus | 1980 |
Catechol oestrogens and gonadotrophin secretion in the ewe: affinity for pituitary oestrogen receptors invitro and action on gonadotrophin secretion in vivo.
Topics: Animals; Castration; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hydroxyestrones; In Vitro Techniques; Luteinizing Hormone; Pituitary Gland; Receptors, Estrogen; Sheep | 1980 |
Stimulation of release of luteinizing hormone from cultured pituitary cells by 2- and 4-hydroxylated oestrogens.
Topics: Animals; Cells, Cultured; Estradiol; Estrogens, Catechol; Estrone; Female; Follicle Stimulating Hormone; Hydroxyestrones; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Secretory Rate; Stimulation, Chemical | 1981 |
Does 2-hydroxyestrone suppress prolactin in women?
Topics: Adult; Circadian Rhythm; Estrone; Female; Follicle Stimulating Hormone; Humans; Hydroxyestrones; Luteinizing Hormone; Prolactin; Time Factors | 1982 |
Catecholestrogens affect catecholamine turnover rates in the anterior part of the mediobasal hypothalamus and medial preoptic area in the male and female castrated rat.
Topics: Animals; Castration; Dopamine; Epinephrine; Estradiol; Estrone; Female; Hydroxyestrones; Hypothalamus; Male; Norepinephrine; Preoptic Area; Rats; Rats, Inbred Strains; Sex Factors | 1983 |
A comparison of the effects of 4-catechol oestrogens and 2-pyrogallol oestrogens on prostaglandin synthesis by the rat and human uterus.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Estradiol; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Uterus | 1981 |
Radioimmunoassay and metabolism of the catechol estrogen 2-hydroxyestradiol.
Topics: 2-Methoxyestradiol; Adult; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Estradiol; Female; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Middle Aged; Radioimmunoassay | 1982 |
Metabolic clearance rate and conversion ratios of [3H]2-hydroxyestrone in normal men.
Topics: Adult; Estrone; Glucuronates; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Sulfates | 1982 |
The effect of catecholestrogens on the growth of prolactin-secreting pituitary tumors and normal prolactin synthesis in the rat.
Topics: Adrenal Glands; Animals; Estradiol; Estriol; Estrone; Female; Hydroxyestrones; Neoplasm Transplantation; Organ Size; Ovary; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Uterus | 1982 |
Induction and inhibition of uterine vasodilation by catechol estrogen in oophorectomized, nonpregnant ewes.
Topics: Animals; Blood Flow Velocity; Castration; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Hydroxyestrones; Pregnancy; Sheep; Uterus; Vasodilation | 1982 |
Competition by estrogens for catecholamine receptor binding in vitro.
Topics: Animals; Binding, Competitive; Brain; Cerebral Cortex; Corpus Striatum; Dioxanes; Estradiol; Estrogens; Female; Hydroxyestrones; Pituitary Gland, Anterior; Prazosin; Rats; Receptors, Adrenergic; Spiperone; Tetrahydronaphthalenes | 1982 |
Synthesis of [2H8] estradiol, [2H7] estrone, [2H6] 2-hydroxyestrone and [2H6] 4-hydroxyestrone as internal standards for selected ion monitoring.
Topics: Deuterium; Estradiol; Estrone; Gas Chromatography-Mass Spectrometry; Hydroxyestrones; Isotope Labeling; Reference Standards | 1982 |
2-Hydroxyestrone suppresses and 2-methoxyestrone augments the preovulatory prolactin surge in the cycling rat.
Topics: Animals; Estradiol; Estrone; Female; Hydroxyestrones; Ovulation; Pregnancy; Proestrus; Prolactin; Rats | 1982 |
Central and peripheral action of estradiol and catecholestrogens administered at low concentration by constant infusion.
Topics: Animals; Behavior, Animal; Brain; Cell Nucleus; Cytosol; Estradiol; Estrogens, Catechol; Estrone; Female; Glucosephosphate Dehydrogenase; Hydroxyestrones; Pituitary Gland; Posture; Rats; Receptors, Estrogen; Receptors, Progesterone | 1981 |
Studies on steroids. CLXV. Determination of isomeric catechol estrogens in pregnancy urine by high performance liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Isomerism; Pregnancy; Reference Values | 1981 |
Failure of 2-hydroxyoestrone to lower prolactin concentrations in hyperprolactinaemic women.
Topics: Adult; Anovulation; Depression, Chemical; Estrone; Female; Humans; Hydroxyestrones; Luteinizing Hormone; Prolactin | 1981 |
[A rapid radioimmunoassay of steroid-hormone using dried Staphylococcus aureus (author's transl)].
Topics: Estrone; Humans; Hydroxyestrones; Radioimmunoassay; Staphylococcus aureus | 1981 |
Suppression of prolactin secretion in normal young women by 2-hydroxyestrone.
Topics: Adult; Drug Administration Schedule; Estrogens; Estrone; Female; Humans; Hydroxyestrones; Prolactin; Time Factors | 1980 |
Rapid metabolic clearance of the catechol estrogen 2-hydroxyestrone.
Topics: Adult; Estrone; Humans; Hydroxyestrones; Kinetics; Metabolic Clearance Rate; Radioimmunoassay | 1980 |
Metabolic clearance rate and uterotropic activity of 2-hydroxyestrone in rats.
Topics: Animals; Cytosol; Estrone; Female; Hydroxyestrones; Metabolic Clearance Rate; Rats; Uterine Contraction; Uterus | 1981 |
Monoclonal antibody-based enzyme immunoassay for simultaneous quantitation of 2- and 16 alpha-hydroxyestrone in urine.
Topics: Antibodies, Monoclonal; Autoanalysis; Cost-Benefit Analysis; Estrogens, Catechol; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Immunoenzyme Techniques; Time Factors | 1994 |
Catechol estrogens are more potent antioxidants than estrogens for the Cu(2+)-catalyzed oxidation of low or high density lipoprotein: antioxidative effects of steroids on lipoproteins.
Topics: Antioxidants; Copper; Estradiol; Estriol; Estrogens; Estrogens, Catechol; Estrone; Humans; Hydroxyestrones; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Male; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances | 1994 |
Re: Estrogen metabolism and excretion in Oriental and Caucasian women.
Topics: Animals; Asian People; Breast Neoplasms; Estrogens; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Mammary Neoplasms, Experimental; White People | 1994 |
Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis.
Topics: Animals; Catechol O-Methyltransferase; Cell Transformation, Neoplastic; Chromatography, Gas; Cricetinae; Estrogens; Estrone; Hydroxyestrones; Hydroxylation; Kidney; Male; Mesocricetus; Microsomes; Microsomes, Liver; Steroid 16-alpha-Hydroxylase | 1994 |
Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or beta-naphthaflavone: a comparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods.
Topics: Animals; Ascorbic Acid; Benzoflavones; beta-Naphthoflavone; Estradiol; Estrogens, Catechol; Female; Gas Chromatography-Mass Spectrometry; Hydroxyestrones; Hydroxylation; Indoles; Microsomes, Liver; Radiometry; Rats; Rats, Sprague-Dawley | 1994 |
Radioimmunoassay of 2-hydroxyestrone in urine.
Topics: Adult; Breast Neoplasms; Drug Stability; Female; Humans; Hydrolysis; Hydroxyestrones; Menstruation; Postmenopause; Radioimmunoassay; Reference Values; Sensitivity and Specificity | 1994 |
Omeprazole fails to alter the cytochrome P450-dependent 2-hydroxylation of estradiol in male volunteers.
Topics: Administration, Oral; Adult; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Estriol; Estrone; Humans; Hydroxyestrones; Hydroxylation; Male; Middle Aged; Omeprazole; Radioimmunoassay; Steroid Hydroxylases | 1993 |
Estrogen metabolite ratios and risk assessment of hormone-related cancers. Assay validation and prediction of cervical cancer risk.
Topics: Biopsy; Estriol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Menstrual Cycle; Predictive Value of Tests; Premenopause; Reference Values; Reproducibility of Results; Risk Assessment; Risk Factors; Surveys and Questionnaires; Uterine Cervical Neoplasms; Vaginal Smears | 1995 |
Effect of catecholestrogens on [3H]-GABA uptake by hypothalamic crude synaptosomes.
Topics: Animals; Estradiol; Estrogens, Catechol; Estrone; Female; gamma-Aminobutyric Acid; Hydroxyestrones; Hypothalamus; In Vitro Techniques; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium | 1995 |
Effects of pesticides on the ratio of 16 alpha/2-hydroxyestrone: a biologic marker of breast cancer risk.
Topics: Biomarkers; Breast Neoplasms; Estradiol; Estrogens, Catechol; Humans; Hydroxyestrones; Insecticides; Tumor Cells, Cultured | 1995 |
Synthesis of N-acetylcysteine conjugates of catechol estrogens.
Topics: Acetylcysteine; Estrogens, Catechol; Hydroxyestrones; Magnetic Resonance Spectroscopy; Molecular Structure | 1996 |
Measurement of urinary estrogen metabolites using a monoclonal enzyme-linked immunoassay kit: assay performance and feasibility for epidemiological studies.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Epidemiologic Methods; Estrogens; Estrogens, Catechol; Evaluation Studies as Topic; Feasibility Studies; Female; Follicular Phase; Humans; Hydroxyestrones; Luteal Phase; Menstrual Cycle; Middle Aged; Premenopause; Reagent Kits, Diagnostic; Time Factors | 1996 |
Altered hydroxylation of estrogen in patients with postmenopausal osteopenia.
Topics: Aged; Body Height; Body Mass Index; Body Weight; Bone Density; Bone Diseases, Metabolic; Estrogens; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Hydroxylation; Middle Aged; Postmenopause; Steroid 16-alpha-Hydroxylase | 1997 |
A pilot study of urinary estrogen metabolites (16alpha-OHE1 and 2-OHE1) in postmenopausal women with and without breast cancer.
Topics: Breast Neoplasms; Case-Control Studies; Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; Menopause; Middle Aged; Neoplasms, Hormone-Dependent; Pilot Projects; Risk Factors; Steroid 16-alpha-Hydroxylase | 1997 |
Quantifying estrogen metabolism: an evaluation of the reproducibility and validity of enzyme immunoassays for 2-hydroxyestrone and 16alpha-hydroxyestrone in urine.
Topics: Adult; Biomarkers; Breast Neoplasms; Estrogens; Evaluation Studies as Topic; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Immunoenzyme Techniques; Luteal Phase; Menopause; Middle Aged; Neoplasms, Hormone-Dependent; Reproducibility of Results; Risk Factors | 1997 |
Urinary estrogen metabolites and breast cancer: a case-control study.
Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; New York; Postmenopause; Risk | 1997 |
Effect of estradiol metabolites on the susceptibility of low density lipoprotein to oxidation.
Topics: Estradiol; Estrogens, Catechol; Humans; Hydroxyestrones; Kinetics; Lipoproteins, LDL; Oxidation-Reduction; Vitamin E | 1997 |
Induction of 16alpha-/2-hydroxyestrone metabolite ratios in MCF-7 cells by pesticides, carcinogens, and antiestrogens does not predict mammary carcinogens.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 Enzyme System; Drug Screening Assays, Antitumor; Estrogen Antagonists; Female; Humans; Hydroxyestrones; Mammary Neoplasms, Experimental; Pesticides; Predictive Value of Tests; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tumor Cells, Cultured | 1998 |
New role for estrogen in cancer?
Topics: Animals; Carcinogens; Estrogens; Female; Humans; Hydroxyestrones; Mutagens; Neoplasms | 1998 |
Differential effects of estrogen metabolites on bone and reproductive tissues of ovariectomized rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Cell Division; Cholesterol; Epithelial Cells; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Hypercholesterolemia; Mammary Glands, Animal; Ovariectomy; Rats; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Structure-Activity Relationship; Tibia; Uterus | 1998 |
Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk.
Topics: Age Factors; Anticarcinogenic Agents; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cell Transformation, Neoplastic; Confidence Intervals; Contraceptives, Oral; Disease Progression; Estradiol; Estrogens, Catechol; Female; Forecasting; Humans; Hydroxyestrones; Hydroxylation; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Linear Models; Logistic Models; Menopause; Middle Aged; Odds Ratio; Parity; Risk Factors | 1998 |
Do urinary oestrogen metabolites predict breast cancer? Guernsey III cohort follow-up.
Topics: Adult; Breast Neoplasms; Cohort Studies; Female; Follow-Up Studies; Humans; Hydroxyestrones; Incidence; Predictive Value of Tests; Prospective Studies; Risk Factors | 1998 |
Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7.
Topics: Estradiol; Estrogens, Catechol; Flunitrazepam; Glucuronates; Glucuronosyltransferase; Humans; Hydroxyestrones; Isoenzymes; Norepinephrine | 1998 |
Estrogenic and antiestrogenic activities of 16alpha- and 2-hydroxy metabolites of 17beta-estradiol in MCF-7 and T47D human breast cancer cells.
Topics: Breast Neoplasms; Cathepsin D; Cell Division; Creatine Kinase; Estradiol; Estriol; Female; Humans; Hydroxyestrones; Isoenzymes; Promoter Regions, Genetic; Receptors, Estrogen; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1998 |
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and risk of breast cancer in postmenopausal women.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Middle Aged; Odds Ratio; Postmenopause; Radioimmunoassay; Risk; Risk Factors; Steroid 16-alpha-Hydroxylase | 1999 |
The effect of diurnal and menstrual cyclicity and menopausal status on estrogen metabolites: implications for disease-risk assessment.
Topics: Adult; Circadian Rhythm; Female; Humans; Hydroxyestrones; Menopause; Menstrual Cycle; Risk Assessment | 1999 |
Re: "A pilot study of urinary estrogen metabolites (16alpha-OHE1 and 2-OHE1) in postmenopausal women with and without breast cancer".
Topics: Female; Humans; Hydroxyestrones; Middle Aged; Postmenopause | 1998 |
[The effects of E2 and it's metabolites on the proliferation of rat anterior pituitary cells in vitro].
Topics: Animals; Cell Division; Cells, Cultured; Dopamine Antagonists; Estradiol; Hydroxyestrones; Male; Piribedil; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley | 1997 |
Re: Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and risk of breast cancer in postmenopausal women.
Topics: Adult; Breast Neoplasms; Female; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Research Design; Risk; Risk Factors | 1999 |
Within-person variability of the ratios of urinary 2-hydroxyestrone to 16alpha-hydroxyestrone in Caucasian women.
Topics: Adult; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Middle Aged; Reproducibility of Results; White People | 1999 |
Reproducibility of plasma and urinary sex hormone levels in premenopausal women over a one-year period.
Topics: Adult; Body Mass Index; Estradiol; Estrone; Female; Follicular Phase; Gonadal Steroid Hormones; Humans; Hydroxyestrones; Luteal Phase; Menarche; Middle Aged; Parity; Premenopause; Progesterone; Reproducibility of Results; Time Factors | 1999 |
A new ELISA kit for measuring urinary 2-hydroxyestrone, 16alpha-hydroxyestrone, and their ratio: reproducibility, validity, and assay performance after freeze-thaw cycling and preservation by boric acid.
Topics: Boric Acids; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Estrogens, Catechol; Female; Freezing; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Population Surveillance; Postmenopause; Premenopause; Preservatives, Pharmaceutical; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Single-Blind Method; Time Factors | 2000 |
Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones.
Topics: Adult; Breast Neoplasms; Diet; Female; Glycine max; Humans; Hydroxyestrones; Isoflavones; Neoplasms, Hormone-Dependent; Premenopause | 2000 |
Direct action of naturally occurring estrogen metabolites on human osteoblastic cells.
Topics: Alkaline Phosphatase; Bone Matrix; Cell Differentiation; Cell Line; Enzyme Induction; Estradiol; Estrogen Receptor alpha; Estrogens; Fulvestrant; Humans; Hydroxyestrones; Osteoblasts; Osteocalcin; Receptors, Estrogen; Recombinant Fusion Proteins; RNA, Messenger | 2000 |
Evaluation of an EIA method for measuring serum levels of the estrogen metabolite 2-hydroxyestrone in adults.
Topics: Adult; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Linear Models; Male; Middle Aged; Reference Values; Sensitivity and Specificity | 2001 |
Mutagenic properties of estrogen quinone-derived DNA adducts in simian kidney cells.
Topics: Animals; Base Sequence; Cell Line, Transformed; Chromatography, Liquid; COS Cells; DNA Adducts; DNA Mutational Analysis; Estradiol; Estrogens, Catechol; Estrone; Genetic Vectors; Hydroxyestrones; Kidney; Mass Spectrometry; Molecular Sequence Data; Mutagens; Oligodeoxyribonucleotides; Quinones; Transfection | 2001 |
Re: CYP17 promoter polymorphism and breast cancer in Australian women under age forty years.
Topics: Adolescent; Adult; Asian People; Australia; Black People; Breast Neoplasms; Female; Genotype; Humans; Hydroxyestrones; Native Hawaiian or Other Pacific Islander; Polymorphism, Genetic; Promoter Regions, Genetic; Steroid 17-alpha-Hydroxylase; White People | 2001 |
In vitro generation of peroxynitrite by 2- and 4-hydroxyestrogens in the presence of nitric oxide.
Topics: Chromatography, High Pressure Liquid; Estradiol; Estrogens, Catechol; Hydroxyestrones; Mass Spectrometry; Nitrates; Nitric Oxide | 2001 |
Urinary estrogen metabolites and mammographic parenchymal patterns in postmenopausal women.
Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Epidemiologic Studies; Estrogens; Female; Humans; Hydroxyestrones; Mammography; Middle Aged; Postmenopause; Risk Factors; Steroid 16-alpha-Hydroxylase | 2001 |
Urinary excretion pattern of catecholestrogens in preovulatory LH surge during the 4-day estrous cycle of rats.
Topics: Animals; Diestrus; Estradiol; Estriol; Estrogens, Catechol; Estrone; Estrus; Female; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyestrones; Luteinizing Hormone; Male; Metestrus; Ovulation; Proestrus; Rabbits; Radioimmunoassay; Rats | 2001 |
Tissue-selective effects of continuous release of 2-hydroxyestrone and 16alpha-hydroxyestrone on bone, uterus and mammary gland in ovariectomized growing rats.
Topics: Animals; Bone Remodeling; Cholesterol; Dose-Response Relationship, Drug; Drug Implants; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Humans; Hydroxyestrones; Mammary Glands, Animal; Models, Animal; Organ Size; Ovariectomy; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Uterus | 2001 |
Effect of dietary soy isoflavone aglycones on the urinary 16alpha-to-2-hydroxyestrone ratio in C3H/HeJ mice.
Topics: Animals; Anticarcinogenic Agents; Biomarkers; Cytochrome P-450 Enzyme System; Female; Genistein; Glycine max; Hydroxyestrones; Indoles; Isoflavones; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Microsomes, Liver; Organ Size; Plant Extracts | 2000 |
The ability of four catechol estrogens of 17beta-estradiol and estrone to induce DNA adducts in Syrian hamster embryo fibroblasts.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; DNA Adducts; Estradiol; Estrogens, Catechol; Fibroblasts; Hydroxyestrones; Mesocricetus | 2001 |
The effects of postmenopausal hormone replacement therapy and oral contraceptives on the endogenous estradiol metabolism.
Topics: Adult; Contraceptives, Oral; Estradiol; Estrogen Replacement Therapy; Estrogens, Catechol; Ethinyl Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Nandrolone; Norethindrone; Norethindrone Acetate; Postmenopause | 2001 |
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women.
Topics: Adult; Biomarkers; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; Genetic Predisposition to Disease; Humans; Hydroxyestrones; Middle Aged; Premenopause | 2002 |
Stable isotope dilution high-performance liquid chromatography-electrospray ionization mass spectrometry method for endogenous 2- and 4-hydroxyestrones in human urine.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Hydrolysis; Hydroxyestrones; Isotopes; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2002 |
Effects of prune consumption on the ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone.
Topics: Body Composition; Body Constitution; Body Mass Index; Body Weight; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Energy Intake; Follicular Phase; Fruit; Hydroxyestrones; Luteal Phase; Premenopause; Prunus | 2002 |
A preliminary study of the effect of fluoxetine treatment on the 2:16-alpha-hydroxyestrone ratio in young women.
Topics: Adult; Cytochrome P-450 Enzyme System; Female; Fluoxetine; Humans; Hydroxyestrones; Isoenzymes; Pilot Projects | 2003 |
Predictors of the plasma ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups.
Topics: Administration, Oral; Adolescent; Adult; Black People; Breast Neoplasms; Contraceptive Agents; Estrogen Replacement Therapy; Ethnicity; Female; Humans; Hydroxyestrones; Menstrual Cycle; Parity; Premenopause; Risk Factors; White People | 2003 |
Influence of postmenopausal hormone replacement therapy on an estrogen metabolite biomarker of risk for breast cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cross-Sectional Studies; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxyestrones; Medroxyprogesterone Acetate; Postmenopause; Risk Factors | 2003 |
2-hydroxyestrone: a new metabolite of estradiol in man.
Topics: Estradiol; Humans; Hydroxyestrones; Male | 1960 |
Role of 2-hydroxyestrone in estrogen metabolism.
Topics: Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Hydroxyestrones | 1963 |
Estrogen metabolites and the risk of breast cancer in older women.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Cohort Studies; Estrogens; Female; Humans; Hydroxyestrones; Risk Factors; Steroid 16-alpha-Hydroxylase; Surveys and Questionnaires | 2003 |
Endogenous estradiol metabolism during treatment with oral contraceptives.
Topics: Adult; Contraceptives, Oral, Combined; Estradiol; Ethinyl Estradiol; Female; Humans; Hydroxyestrones; Levonorgestrel; Nandrolone; Norethindrone; Premenopause; Randomized Controlled Trials as Topic | 2004 |
Associations between aerobic fitness and estrogen metabolites in premenopausal women.
Topics: Adult; Analysis of Variance; Body Mass Index; Estriol; Exercise; Exercise Test; Female; Humans; Hydroxyestrones; Physical Fitness; Premenopause | 2005 |
A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio.
Topics: Adult; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Base Sequence; Black or African American; Cytochrome P-450 CYP1B1; Deoxyribonuclease HpaII; DNA; Estradiol; Female; Genetics, Population; Humans; Hydroxyestrones; Male; Middle Aged; Polymorphism, Genetic; White People | 2005 |
Urinary estrogen metabolites, prostate specific antigen, and body mass index among African-American men in South Carolina.
Topics: Adult; Aged; Black or African American; Body Mass Index; Estrogens; Humans; Hydroxyestrones; Male; Middle Aged; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; South Carolina | 2005 |
Estrogen metabolism and breast cancer.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Middle Aged; New York; Surveys and Questionnaires | 2006 |
Selected diet and lifestyle factors are associated with estrogen metabolites in a multiracial/ethnic population of women.
Topics: Anticarcinogenic Agents; Body Size; Diet; Estrogens; Ethnicity; Exercise; Female; Flavonoids; Humans; Hydroxyestrones; Life Style; Middle Aged; Phenols; Polyphenols; Population Surveillance; Smoking; United States | 2006 |
Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: Insights into the structural determinants favoring a differential subtype binding.
Topics: Diethylstilbestrol; Estradiol; Estriol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Estrone; Humans; Hydroxyestrones; Models, Molecular; Molecular Structure; Phytoestrogens; Quantitative Structure-Activity Relationship; Signal Transduction; Static Electricity | 2006 |
Estradiol and its metabolites and their association with knee osteoarthritis.
Topics: Adult; Estradiol; Female; Humans; Hydroxyestrones; Longitudinal Studies; Michigan; Middle Aged; Odds Ratio; Osteoarthritis, Knee; Radiography; Risk Factors | 2006 |
Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: a pilot study comparing pre- and post-operative levels.
Topics: Adjuvants, Pharmaceutic; Aged; Aged, 80 and over; Alcohol Drinking; Breast Neoplasms; Coffee; Cytochrome P-450 CYP1A2; Estrogen Antagonists; Estrogens; Female; Humans; Hydroxyestrones; Hydroxytestosterones; Middle Aged; Pilot Projects; Postoperative Period; Receptors, Estrogen; Tamoxifen | 2006 |
Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress.
Topics: Biomarkers; Estradiol; Female; Humans; Hydroxyestrones; Isoprostanes; Middle Aged; Oxidative Stress | 2008 |
Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats.
Topics: Animals; Benzophenones; Biomarkers; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cervical Ripening; Cervix Uteri; Estradiol; Estriol; Female; Hydroxyestrones; Immunohistochemistry; In Vitro Techniques; Mifepristone; Models, Animal; Obstetric Labor, Premature; Pregnancy; Rats; Rats, Sprague-Dawley | 2007 |
Ethnicity, body size, and estrogen levels in postmenopausal Hispanic and non-Hispanic white women.
Topics: Aged; Body Size; Breast Neoplasms; Cross-Sectional Studies; Female; Follow-Up Studies; Hispanic or Latino; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Risk; White People | 2009 |
Urinary estrogen metabolites in women at high risk for breast cancer.
Topics: Adult; Aged; Alcohol Drinking; Body Mass Index; Breast Neoplasms; Female; Humans; Hydroxyestrones; Linear Models; Middle Aged; Smoking | 2009 |
Effect of flaxseed consumption on urinary levels of estrogen metabolites in postmenopausal women.
Topics: 2-Methoxyestradiol; Body Mass Index; Diet; Energy Intake; Estradiol; Estrogens; Female; Flax; Humans; Hydroxyestrones; Middle Aged; Postmenopause | 2010 |
Serum concentrations of selected endogenous estrogen and estrogen metabolites in pre- and post-menopausal Chinese women with osteoarthritis.
Topics: Adult; Aged; Asian People; Case-Control Studies; Chromatography, High Pressure Liquid; Estradiol; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; Osmolar Concentration; Osteoarthritis; Postmenopause; Premenopause | 2010 |
Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma.
Topics: Adult; Androstenediol; Androstenedione; Carcinoma, Papillary; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Male; Middle Aged; Multivariate Analysis; Postmenopause; Premenopause; Sex Factors; Steroids; Thyroid Neoplasms | 2011 |
Postmenopausal circulating levels of 2- and 16α-hydroxyestrone and risk of endometrial cancer.
Topics: Aged; Case-Control Studies; Endometrial Neoplasms; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; Prospective Studies | 2011 |
Anti-proliferative effects of Chinese herb Cornus officinalis in a cell culture model for estrogen receptor-positive clinical breast cancer.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Aggregation; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cornus; Drugs, Chinese Herbal; Estradiol; Female; Fruit; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Models, Biological; Plant Extracts; Receptors, Estrogen | 2012 |
Multi-nutrient supplement improves hormone ratio associated with cancer risk.
Topics: Case-Control Studies; Dietary Supplements; Female; Follow-Up Studies; Humans; Hydroxyestrones; Middle Aged; Neoplasms; Risk Factors | 2013 |
Comparative efficacy of extracts from Lycium barbarum bark and fruit on estrogen receptor positive human mammary carcinoma MCF-7 cells.
Topics: Cell Proliferation; Fruit; Humans; Hydroxyestrones; Inhibitory Concentration 50; Lycium; MCF-7 Cells; Plant Bark; Plant Extracts; Receptors, Estrogen | 2014 |
Circulating estrogen metabolites and risk of breast cancer in postmenopausal women.
Topics: Breast Neoplasms; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Estrogens; Estrone; Female; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Risk | 2014 |
The ratio of the estradiol metabolites 2-hydroxyestrone (2-OHE1) and 16α-hydroxyestrone (16-OHE1) may predict breast cancer risk in postmenopausal but not in premenopausal women: two case-control studies.
Topics: Adult; Biomarkers; Breast Neoplasms; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogens; Female; Genetic Predisposition to Disease; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Premenopause; Sensitivity and Specificity | 2015 |
Elevation of C-reactive protein during the luteal phase in healthy adolescents.
Topics: Adolescent; Adolescent Development; Biomarkers; C-Reactive Protein; Chile; Female; Follicular Phase; Humans; Hydroxyestrones; Luteal Phase; Progesterone; Reference Values; Up-Regulation; Urban Health | 2015 |
Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Estradiol; Estriol; Estrogens; Estrone; Female; Follicular Phase; Humans; Hydroxyestrones; Limit of Detection; Luteal Phase; Middle Aged; Osteoarthritis; Postmenopause; Premenopause; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric | 2015 |
The effect of oral 3,3'-diindolylmethane supplementation on the 2:16α-OHE ratio in BRCA1 mutation carriers.
Topics: Administration, Oral; Adult; Female; Genes, BRCA1; Heterozygote; Humans; Hydroxyestrones; Indoles; Middle Aged; Mutation | 2015 |
[Determination of 2-hydroxyestrone /16α-hydroxyestrone ratio in urine of Mexican women as a risk indicator for breast cancer and its relationship with other risk factors].
Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cross-Sectional Studies; Female; Humans; Hydroxyestrones; Male; Mexico; Middle Aged; Risk Factors; Young Adult | 2014 |
Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner.
Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Chickens; Cyclooxygenase 1; Cyclooxygenase 2; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP3A; Diet; Dietary Supplements; Dinoprostone; Estrogen Receptor alpha; Estrogens; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Flax; Hydroxyestrones; Lignans; Liver; Ovarian Neoplasms; Ovary; RNA, Messenger | 2015 |
Oxidative Metabolism of Estrone Modified by Genistein and Bisphenol A in Rat Liver Microsomes.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Breast Neoplasms; Drug Synergism; Endocrine Disruptors; Estrone; Genistein; Hydroxyestrones; Male; Microsomes, Liver; Oxidation-Reduction; Phenols; Rats, Wistar | 2015 |
Relation of Serum Estrogen Metabolites with Terminal Duct Lobular Unit Involution Among Women Undergoing Diagnostic Image-Guided Breast Biopsy.
Topics: Adult; Breast; Breast Neoplasms; Chromatography, Liquid; Cross-Sectional Studies; Estradiol; Female; Humans; Hydroxyestrones; Image-Guided Biopsy; Middle Aged; Postmenopause; Premenopause; Tandem Mass Spectrometry | 2016 |
Opposite estrogen effects of estrone and 2-hydroxyestrone on MCF-7 sensitivity to the cytotoxic action of cell growth, oxidative stress and inflammation activity.
Topics: Cell Proliferation; Endocrine Disruptors; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Inflammation; MCF-7 Cells; Molecular Docking Simulation; Oxidative Stress; Toxicity Tests | 2021 |
Association of microbial dynamics with urinary estrogens and estrogen metabolites in patients with endometriosis.
Topics: Adult; Chromatography, Liquid; Dysbiosis; Endometriosis; Estradiol; Estrogens; Female; Humans; Hydroxyestrones; Microbiota; RNA, Ribosomal, 16S; Tandem Mass Spectrometry | 2021 |
Establishment and validation of a sensitive LC-MS/MS method for quantification of urinary estrogens in women with gestational diabetes mellitus.
Topics: Chromatography, Liquid; Creatinine; Diabetes, Gestational; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydroxyestrones; Pregnancy; Tandem Mass Spectrometry | 2022 |