Compounds > estrone-3-o-sulfamate

Page last updated: 2024-09-03

estrone-3-o-sulfamate and warfarin

estrone-3-o-sulfamate has been researched along with warfarin in 12 studies

Compound Research Comparison

Studies (estrone-3-o-sulfamate)	Trials (estrone-3-o-sulfamate)	Recent Studies (post-2010) (estrone-3-o-sulfamate)	Studies (warfarin)	Trials (warfarin)	Recent Studies (post-2010) (warfarin)
89	0	15	36,573	2,143	14,728

Protein Interaction Comparison

Protein	Taxonomy	estrone-3-o-sulfamate (IC50)	warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1	Homo sapiens (human)		0.0088

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (75.00)	29.6817
2010's	3 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Malini, B; Potter, BV; Purohit, A; Reed, MJ; Woo, LL	1
Ahmed, S; James, K; Owen, CP; Patel, CK; Patel, M	2
Ahmed, S; James, K; Owen, CP; Patel, CK; Patel, MB	1
Ahmed, S; James, K; Owen, CP; Patel, CK	1
Ahmed, S; James, K; Owen, CP	2
Chander, SK; Potter, BV; Purohit, A; Reed, MJ; Woo, LW	1
Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Woo, LW	1
Ishida, H; Nakata, T; Shiotsu, Y	1
Edwards, DR; Wolfenden, R	1
Potter, BV; Thomas, MP	1

Reviews

3 review(s) available for estrone-3-o-sulfamate and warfarin

Article	Year
Steroid sulfatase: molecular biology, regulation, and inhibition. Endocrine reviews, 2005, Volume: 26, Issue:2 Topics: Animals; Breast Neoplasms; Clinical Trials, Phase I as Topic; Coumarins; Enzyme Inhibitors; Estrone; Female; Humans; Models, Molecular; Neoplasms, Hormone-Dependent; Steryl-Sulfatase; Sulfonamides; Sulfonic Acids	2005
[Steroid sulfatase inhibitor]. Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68, Issue:6 Topics: Animals; Breast Neoplasms; Clinical Trials as Topic; Coumarins; Drug Design; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Steryl-Sulfatase; Sulfonamides	2010
Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential. The Journal of steroid biochemistry and molecular biology, 2015, Volume: 153 Topics: Animals; Coumarins; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Humans; Models, Molecular; Steryl-Sulfatase; Sulfonamides	2015

Other Studies

9 other study(ies) available for estrone-3-o-sulfamate and warfarin

Article	Year
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates. Chemistry & biology, 2000, Volume: 7, Issue:10 Topics: Alanine; Antineoplastic Agents; Arylsulfatases; Binding Sites; Breast Neoplasms; Coumarins; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estrone; Female; Glycine; Heterocyclic Compounds, 3-Ring; Humans; Hydrogen Bonding; Kinetics; Microsomes; Models, Molecular; Placenta; Postmenopause; Steryl-Sulfatase; Structure-Activity Relationship; Sulfatases; Sulfonamides; Sulfonic Acids	2000
Novel inhibitors of the enzyme estrone sulfatase (ES). Bioorganic & medicinal chemistry letters, 2001, Mar-26, Volume: 11, Issue:6 Topics: Alkanes; Coumarins; Enzyme Inhibitors; Estrone; Inhibitory Concentration 50; Ketones; Mesylates; Sulfatases; Sulfonamides; Sulfonic Acids	2001
Hydrophobicity, a physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES). Bioorganic & medicinal chemistry letters, 2001, Sep-17, Volume: 11, Issue:18 Topics: Chemistry, Physical; Coumarins; Enzyme Inhibitors; Estrone; Inhibitory Concentration 50; Models, Biological; Models, Chemical; Structure-Activity Relationship; Sulfatases; Sulfonamides	2001
Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism. Bioorganic & medicinal chemistry letters, 2001, Dec-03, Volume: 11, Issue:23 Topics: Catalytic Domain; Coumarins; Enzyme Inhibitors; Estrone; Inhibitory Concentration 50; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Sulfatases; Sulfonamides; Sulfonic Acids	2001
Synthesis and biochemical evaluation of novel and potent inhibitors of the enzyme oestrone sulphatase (ES). The Journal of steroid biochemistry and molecular biology, 2002, Volume: 80, Issue:4-5 Topics: Coumarins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrone; Humans; Hydrolysis; Inhibitory Concentration 50; Kinetics; Microsomes; Models, Chemical; Placenta; Spectrophotometry, Infrared; Sulfatases; Sulfonamides; Time Factors	2002
The design, synthesis, and biochemical evaluation of derivatives of biphenyl sulfamate-based compounds as novel inhibitors of estrone sulfatase. Biochemical and biophysical research communications, 2002, May-31, Volume: 294, Issue:1 Topics: Catalysis; Coumarins; Enzyme Inhibitors; Estrone; Models, Chemical; Models, Molecular; Sulfatases; Sulfonamides	2002
Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES). The Journal of steroid biochemistry and molecular biology, 2002, Volume: 82, Issue:4-5 Topics: Coumarins; Drug Design; Enzyme Inhibitors; Estrone; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Mimicry; Structure-Activity Relationship; Sulfatases; Sulfonamides; Sulfonic Acids	2002
The role of steroid sulphatase in regulating the oestrogenicity of oestrogen sulphamates. Biochemical and biophysical research communications, 2004, Sep-10, Volume: 322, Issue:1 Topics: Animals; Coumarins; Drug Combinations; Estrogens; Estrone; Female; Homeostasis; Organ Size; Ovariectomy; Rats; Rats, Wistar; Steryl-Sulfatase; Sulfonamides; Sulfonic Acids; Uterus	2004
Proton-in-flight mechanism for the spontaneous hydrolysis of N-methyl O-phenyl sulfamate: implications for the design of steroid sulfatase inhibitors. The Journal of organic chemistry, 2012, May-04, Volume: 77, Issue:9 Topics: Arylsulfatases; Catalysis; Coumarins; Esters; Estrone; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molecular Structure; Steryl-Sulfatase; Sulfonamides; Sulfonic Acids	2012