Page last updated: 2024-09-03

estrone-3-o-sulfamate and letrozole

estrone-3-o-sulfamate has been researched along with letrozole in 2 studies

Compound Research Comparison

Studies (estrone-3-o-sulfamate)	Trials (estrone-3-o-sulfamate)	Recent Studies (post-2010) (estrone-3-o-sulfamate)	Studies (letrozole)	Trials (letrozole)	Recent Studies (post-2010) (letrozole)
89	0	15	2,612	612	1,602

Protein Interaction Comparison

Protein	Taxonomy	letrozole (IC50)
Steryl-sulfatase	Homo sapiens (human)	0.0009
Aromatase	Homo sapiens (human)	0.009
Cytochrome P450 11B1, mitochondrial	Homo sapiens (human)	2.62
Cytochrome P450 11B2, mitochondrial	Homo sapiens (human)	1.42
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	0.0009

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Acharya, KR; Chander, SK; Cozier, G; Jackson, T; Leonard, P; Potter, BV; Purohit, A; Putey, A; Reed, MJ; Woo, LW	1
Potter, BV; Thomas, MP	1

Other Studies

2 other study(ies) available for estrone-3-o-sulfamate and letrozole

Article	Year
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template. Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5 Topics: Animals; Aromatase Inhibitors; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Female; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Steryl-Sulfatase; Structure-Activity Relationship; Triazoles	2010
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health. Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19 Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators	2015

Article

Year

Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.

Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

Topics: Animals; Aromatase Inhibitors; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Female; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Steryl-Sulfatase; Structure-Activity Relationship; Triazoles

2010

Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.

Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators

2015