Page last updated: 2024-09-03

estrone-3-o-sulfamate and letrozole

estrone-3-o-sulfamate has been researched along with letrozole in 2 studies

Compound Research Comparison

Studies
(estrone-3-o-sulfamate)
Trials
(estrone-3-o-sulfamate)
Recent Studies (post-2010)
(estrone-3-o-sulfamate)
Studies
(letrozole)
Trials
(letrozole)
Recent Studies (post-2010) (letrozole)
890152,6126121,602

Protein Interaction Comparison

ProteinTaxonomyestrone-3-o-sulfamate (IC50)letrozole (IC50)
Steryl-sulfataseHomo sapiens (human)0.0009
AromataseHomo sapiens (human)0.009
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)2.62
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)1.42
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.0009

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acharya, KR; Chander, SK; Cozier, G; Jackson, T; Leonard, P; Potter, BV; Purohit, A; Putey, A; Reed, MJ; Woo, LW1
Potter, BV; Thomas, MP1

Other Studies

2 other study(ies) available for estrone-3-o-sulfamate and letrozole

ArticleYear
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Animals; Aromatase Inhibitors; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Female; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Steryl-Sulfatase; Structure-Activity Relationship; Triazoles

2010
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators

2015