Page last updated: 2024-09-03

estrone-3-o-sulfamate and estradiol-3-o-sulfamate

estrone-3-o-sulfamate has been researched along with estradiol-3-o-sulfamate in 4 studies

Compound Research Comparison

Studies (estrone-3-o-sulfamate)	Trials (estrone-3-o-sulfamate)	Recent Studies (post-2010) (estrone-3-o-sulfamate)	Studies (estradiol-3-o-sulfamate)	Trials (estradiol-3-o-sulfamate)	Recent Studies (post-2010) (estradiol-3-o-sulfamate)
89	0	15	7	1	5

Protein Interaction Comparison

Protein	Taxonomy	estrone-3-o-sulfamate (IC50)	estradiol-3-o-sulfamate (IC50)
Steryl-sulfatase	Homo sapiens (human)		0.016

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	2 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hejaz, HA; Leese, MP; Mahon, MF; Newman, SP; Potter, BV; Purohit, A; Reed, MJ	1
De Simone, G; Di Fiore, A; Leblond, B; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Smith, A; Supuran, CT	1
Potter, BV; Thomas, MP	2

Reviews

1 review(s) available for estrone-3-o-sulfamate and estradiol-3-o-sulfamate

Article	Year
Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential. The Journal of steroid biochemistry and molecular biology, 2015, Volume: 153 Topics: Animals; Coumarins; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Humans; Models, Molecular; Steryl-Sulfatase; Sulfonamides	2015

Other Studies

3 other study(ies) available for estrone-3-o-sulfamate and estradiol-3-o-sulfamate

Article	Year
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents. Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Estradiol; Estrone; Female; Humans; Mice; Molecular Structure; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Transplantation, Heterologous	2005
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26 Topics: Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Carbonic Anhydrase II; Carcinoma, Lewis Lung; Cell Proliferation; Crystallography, X-Ray; Estradiol; Female; Humans; Mice; Mice, Nude; Models, Molecular; Neovascularization, Pathologic; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc	2006
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health. Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19 Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators	2015