Page last updated: 2024-09-03

estrone-3-o-sulfamate and 2-methoxyestradiol

estrone-3-o-sulfamate has been researched along with 2-methoxyestradiol in 5 studies

Compound Research Comparison

Studies
(estrone-3-o-sulfamate)
Trials
(estrone-3-o-sulfamate)
Recent Studies (post-2010)
(estrone-3-o-sulfamate)
Studies
(2-methoxyestradiol)
Trials
(2-methoxyestradiol)
Recent Studies (post-2010) (2-methoxyestradiol)
8901577911315

Protein Interaction Comparison

ProteinTaxonomyestrone-3-o-sulfamate (IC50)2-methoxyestradiol (IC50)
Tubulin alpha-1A chainSus scrofa (pig)2.2
Tubulin beta chainSus scrofa (pig)2.2
Tubulin beta-2B chainBos taurus (cattle)3.48
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0667
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.9

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ1
Hejaz, HA; Leese, MP; Mahon, MF; Newman, SP; Potter, BV; Purohit, A; Reed, MJ1
Potter, BV; Thomas, MP1
Cortés-Benítez, F; Dutour, R; Poirier, D; Roy, J1
Huang, J; Huang, L; Li, Y; Nie, H; Song, L; Wu, F1

Other Studies

5 other study(ies) available for estrone-3-o-sulfamate and 2-methoxyestradiol

ArticleYear
2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.
    Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Estrogens; Humans; Sulfuric Acid Esters

2004
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
    Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Estradiol; Estrone; Female; Humans; Mice; Molecular Structure; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Transplantation, Heterologous

2005
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators

2015
Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives.
    Bioorganic & medicinal chemistry letters, 2016, 11-01, Volume: 26, Issue:21

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Estrogens; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship

2016
Design, synthesis and biological evaluation of combretastatin A-4 sulfamate derivatives as potential anti-cancer agents.
    RSC medicinal chemistry, 2021, Aug-18, Volume: 12, Issue:8

    Topics:

2021