estrone 3-bromoacetate has been researched along with estrone in 5 studies
*Estrone: An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. [MeSH]
*Estrone: An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. [MeSH]
| Studies (estrone 3-bromoacetate) | Trials (estrone 3-bromoacetate) | Recent Studies (post-2010) (estrone 3-bromoacetate) | Studies (estrone) | Trials (estrone) | Recent Studies (post-2010) (estrone) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 10,266 | 432 | 1,372 |
| Protein | Taxonomy | estrone 3-bromoacetate (IC50) | estrone (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.1261 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 6.589 | |
| 17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | 0.4134 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.301 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.3743 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asibey-Berko, E; Strickler, RC; Thomas, JL | 1 |
| Asibey-Berko, E; LaRochelle, MC; Strickler, RC; Thomas, JL | 1 |
| Bradshaw, RA; Chin, CC; Murdock, GL; Offord, RE; Warren, JC | 1 |
| LaRochelle, MC; Strickler, RC; Thomas, JL | 1 |
| Murdock, GL; Warren, JC | 1 |
5 other study(ies) available for estrone 3-bromoacetate and estrone
| Article | Year |
|---|---|
The affinity alkylators, 11 alpha-bromoacetoxyprogesterone and estrone 3-bromoacetate, modify a common histidyl residue in the active site of human placental 17 beta,20 alpha-hydroxysteroid dehydrogenase.
Topics: Alkylation; Binding Sites; Estradiol Dehydrogenases; Estrone; Female; Histidine; Humans; Hydroxyestrones; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kinetics; Placenta; Pregnancy | 1986 |
Reactivation of human placental 17 beta,20 alpha-hydroxysteroid dehydrogenase affinity alkylated by estrone 3-(bromoacetate): topographic studies with 16 alpha-(bromoacetoxy)estradiol 3-(methyl ether).
Topics: 17-Hydroxysteroid Dehydrogenases; 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Affinity Labels; Alkylation; Amino Acids; Cytosol; Enzyme Activation; Estradiol; Estradiol Dehydrogenases; Estrone; Female; Humans; Hydroxyestrones; Indicators and Reagents; Kinetics; Placenta; Pregnancy; Protein Binding | 1985 |
Human placental estradiol 17 beta-dehydrogenase. Identification of a single histidine residue affinity-labeled by both 3-bromoacetoxyestrone and 12 beta-bromoacetoxy-4-estrene-3,17-dione.
Topics: 17-Hydroxysteroid Dehydrogenases; Affinity Labels; Amino Acids; Binding Sites; Carbon Radioisotopes; Estradiol Dehydrogenases; Estrenes; Estrone; Female; Histidine; Humans; Hydroxyestrones; Peptide Fragments; Placenta; Pregnancy; Trypsin | 1983 |
Reactivation of human placental 17 beta, 20 alpha-hydroxysteroid dehydrogenase: affirmation of affinity labeling principles.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Affinity Labels; Enzyme Activation; Female; Humans; Hydroxyestrones; Kinetics; Placenta; Pregnancy; Protein Binding | 1984 |
Isolation of histidyl peptides of the steroid-binding site of human placental estradiol 17 beta-dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Estradiol Dehydrogenases; Female; Histidine; Humans; Hydroxyestrones; Kinetics; NADP; Peptide Fragments; Placenta; Pregnancy; Trypsin | 1982 |