Page last updated: 2024-08-20

estragole and 1'-hydroxyestragole

estragole has been researched along with 1'-hydroxyestragole in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Drinkwater, NR; Miller, EC; Miller, JA; Pitot, HC1
Anthony, A; Caldwell, J; Hutt, AJ; Smith, RL1
Caldwell, J; Hutt, AJ; Smith, RL; Zangouras, A1
Boersma, MG; Bogaards, JJ; Cnubben, NH; Fiamegos, YC; Jeurissen, SM; Punt, A; Rietjens, IM; Schilter, B; van Bladeren, PJ1
Delatour, T; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ1
Boersma, MG; Delatour, T; Freidig, AP; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ1
Boersma, MG; Delatour, T; Freidig, AP; Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ1
Horst, K; Rychlik, M; Zeller, A1
Boersma, MG; Delatour, T; Jeurissen, SM; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ1
Adams, T; Alhusainy, W; Delatour, T; Louisse, J; Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; Spenkelink, A; van Bladeren, PJ; Vervoort, J1
Alink, G; Gremaud, E; Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; Spenkelink, B; van Bladeren, PJ1
Alhusainy, W; Amer, AO; Jones, DE; Palmer, JM; Probert, PM; Rietjens, IM; White, SA; Wright, MC1
Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; Spenkelink, A; van Bladeren, PJ1
Louisse, J; Ning, J; Rietjens, IMCM; Spenkelink, B; Wesseling, S1
Diem, M; Liu, JDH; Oostenbrink, C; Rietjens, IMCM; Vervoort, J; Wesseling, S; Yang, S1
Kawai, T; Rietjens, IMCM; Wesseling, S; Yang, S1

Other Studies

16 other study(ies) available for estragole and 1'-hydroxyestragole

ArticleYear
Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:6

    Topics: Allylbenzene Derivatives; Animals; Animals, Newborn; Anisoles; Carcinogens; Carcinoma, Hepatocellular; Flavoring Agents; Glucuronates; Liver; Liver Neoplasms; Male; Mice; Mutagens; Neoplasms, Experimental; Nucleosides; Salmonella typhimurium

1976
Metabolism of estragole in rat and mouse and influence of dose size on excretion of the proximate carcinogen 1'-hydroxyestragole.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1987, Volume: 25, Issue:11

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Carbon Dioxide; Carbon Radioisotopes; Dose-Response Relationship, Drug; Female; Flavoring Agents; Male; Mice; Rats; Rats, Inbred Strains

1987
Dose dependent conversion of estragole in the rat and mouse to the carcinogenic metabolite, 1'-hydroxyestragole.
    Biochemical pharmacology, 1981, Jun-01, Volume: 30, Issue:11

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens; Dose-Response Relationship, Drug; Female; Male; Mice; Rats; Species Specificity

1981
Human cytochrome p450 enzyme specificity for the bioactivation of estragole and related alkenylbenzenes.
    Chemical research in toxicology, 2007, Volume: 20, Issue:5

    Topics: Allylbenzene Derivatives; Anisoles; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Eugenol; Flavoring Agents; Humans; Hydroxylation; Microsomes, Liver; Safrole; Substrate Specificity

2007
Tandem mass spectrometry analysis of N2-(trans-Isoestragol-3'-yl)-2'-deoxyguanosine as a strategy to study species differences in sulfotransferase conversion of the proximate carcinogen 1'-hydroxyestragole.
    Chemical research in toxicology, 2007, Volume: 20, Issue:7

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens; Chromatography, Liquid; Deoxyguanosine; Female; Humans; Kinetics; Liver; Male; Mice; Molecular Structure; Rats; Rats, Sprague-Dawley; Risk Factors; Safrole; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Subcellular Fractions; Sulfonic Acids; Sulfotransferases; Tandem Mass Spectrometry

2007
A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat.
    Toxicology and applied pharmacology, 2008, Sep-01, Volume: 231, Issue:2

    Topics: Allyl Compounds; Allylbenzene Derivatives; Animals; Anisoles; Carcinogens; Dose-Response Relationship, Drug; Female; Glucuronides; Inactivation, Metabolic; Kidney; Lung; Male; Models, Biological; Phenols; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfones; Tissue Distribution

2008
Use of physiologically based biokinetic (PBBK) modeling to study estragole bioactivation and detoxification in humans as compared with male rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens; Female; Glucuronides; Humans; Inactivation, Metabolic; Intestine, Small; Kidney; Lung; Male; Microsomes, Liver; Models, Biological; Rats; Reproducibility of Results; Species Specificity; Toxicity Tests

2009
Study of the metabolism of estragole in humans consuming fennel tea.
    Chemical research in toxicology, 2009, Volume: 22, Issue:12

    Topics: Adult; Allylbenzene Derivatives; Anisoles; Chromatography, High Pressure Liquid; Female; Foeniculum; Humans; Hydroxylation; Male; Phenol; Propanols; Tandem Mass Spectrometry

2009
Evaluation of human interindividual variation in bioactivation of estragole using physiologically based biokinetic modeling.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 113, Issue:2

    Topics: Allylbenzene Derivatives; Anisoles; Carcinogens; Cytochrome P-450 Enzyme System; Flavoring Agents; Humans; Liver; Microsomes, Liver; Models, Chemical; Monte Carlo Method; Oxidation-Reduction

2010
Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect.
    Toxicology and applied pharmacology, 2010, Jun-01, Volume: 245, Issue:2

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Flavones; Glucuronides; Hepatocytes; Humans; In Vitro Techniques; Male; Models, Biological; Ocimum basilicum; Oxidation-Reduction; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfotransferases; Toxicity Tests, Acute

2010
In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.
    Mutagenesis, 2012, Volume: 27, Issue:6

    Topics: Administration, Oral; Allylbenzene Derivatives; Animals; Anisoles; Chromatography, Liquid; DNA Adducts; Dose-Response Relationship, Drug; Glucuronides; Kidney; Liver; Lung; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry

2012
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.
    Toxicology letters, 2016, Jan-22, Volume: 243

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Arylsulfotransferase; Carcinogens; Cell Line; Comet Assay; Dehydroepiandrosterone; DNA Damage; Gene Expression Regulation; Hepatocytes; Humans; Hymecromone; Liver; Pregnenolone; Rats; Sulfotransferases

2016
Evaluation of Interindividual Human Variation in Bioactivation and DNA Adduct Formation of Estragole in Liver Predicted by Physiologically Based Kinetic/Dynamic and Monte Carlo Modeling.
    Chemical research in toxicology, 2016, Apr-18, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Allylbenzene Derivatives; Anisoles; Carcinogens; Child, Preschool; Computer Simulation; DNA Adducts; Female; Humans; Infant; Kinetics; Liver; Male; Middle Aged; Models, Biological; Monte Carlo Method; NAD; Oxidation-Reduction; Sulfones; Young Adult

2016
Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling.
    Archives of toxicology, 2017, Volume: 91, Issue:9

    Topics: Administration, Oral; Allylbenzene Derivatives; Anisoles; Arylsulfotransferase; Asian People; Carcinogens; Cytochrome P-450 Enzyme System; Humans; Inactivation, Metabolic; Microsomes, Liver; Models, Biological; White People

2017
Cellular levels and molecular dynamics simulations of estragole DNA adducts point at inefficient repair resulting from limited distortion of the double-stranded DNA helix.
    Archives of toxicology, 2020, Volume: 94, Issue:4

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Carcinogens; Chromatography, Liquid; Cricetinae; Cricetulus; Deoxyguanosine; DNA; DNA Adducts; DNA Repair; Flavoring Agents; Hepatocytes; Mass Spectrometry; Molecular Dynamics Simulation; Rats; Toxicity Tests

2020
In vitro and in silico study on consequences of combined exposure to the food-borne alkenylbenzenes estragole and safrole.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 79

    Topics: Allylbenzene Derivatives; Anisoles; Carcinogens; DNA Adducts; Hep G2 Cells; Humans; Risk Assessment; Safrole

2022