estragole has been researched along with 1'-hydroxyestragole in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Drinkwater, NR; Miller, EC; Miller, JA; Pitot, HC | 1 |
| Anthony, A; Caldwell, J; Hutt, AJ; Smith, RL | 1 |
| Caldwell, J; Hutt, AJ; Smith, RL; Zangouras, A | 1 |
| Boersma, MG; Bogaards, JJ; Cnubben, NH; Fiamegos, YC; Jeurissen, SM; Punt, A; Rietjens, IM; Schilter, B; van Bladeren, PJ | 1 |
| Delatour, T; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ | 1 |
| Boersma, MG; Delatour, T; Freidig, AP; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ | 1 |
| Boersma, MG; Delatour, T; Freidig, AP; Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ | 1 |
| Horst, K; Rychlik, M; Zeller, A | 1 |
| Boersma, MG; Delatour, T; Jeurissen, SM; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; van Bladeren, PJ | 1 |
| Adams, T; Alhusainy, W; Delatour, T; Louisse, J; Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; Spenkelink, A; van Bladeren, PJ; Vervoort, J | 1 |
| Alink, G; Gremaud, E; Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; Spenkelink, B; van Bladeren, PJ | 1 |
| Alhusainy, W; Amer, AO; Jones, DE; Palmer, JM; Probert, PM; Rietjens, IM; White, SA; Wright, MC | 1 |
| Paini, A; Punt, A; Rietjens, IM; Schilter, B; Scholz, G; Spenkelink, A; van Bladeren, PJ | 1 |
| Louisse, J; Ning, J; Rietjens, IMCM; Spenkelink, B; Wesseling, S | 1 |
| Diem, M; Liu, JDH; Oostenbrink, C; Rietjens, IMCM; Vervoort, J; Wesseling, S; Yang, S | 1 |
| Kawai, T; Rietjens, IMCM; Wesseling, S; Yang, S | 1 |
16 other study(ies) available for estragole and 1'-hydroxyestragole
| Article | Year |
|---|---|
Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria.
Topics: Allylbenzene Derivatives; Animals; Animals, Newborn; Anisoles; Carcinogens; Carcinoma, Hepatocellular; Flavoring Agents; Glucuronates; Liver; Liver Neoplasms; Male; Mice; Mutagens; Neoplasms, Experimental; Nucleosides; Salmonella typhimurium | 1976 |
Metabolism of estragole in rat and mouse and influence of dose size on excretion of the proximate carcinogen 1'-hydroxyestragole.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Carbon Dioxide; Carbon Radioisotopes; Dose-Response Relationship, Drug; Female; Flavoring Agents; Male; Mice; Rats; Rats, Inbred Strains | 1987 |
Dose dependent conversion of estragole in the rat and mouse to the carcinogenic metabolite, 1'-hydroxyestragole.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens; Dose-Response Relationship, Drug; Female; Male; Mice; Rats; Species Specificity | 1981 |
Human cytochrome p450 enzyme specificity for the bioactivation of estragole and related alkenylbenzenes.
Topics: Allylbenzene Derivatives; Anisoles; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Eugenol; Flavoring Agents; Humans; Hydroxylation; Microsomes, Liver; Safrole; Substrate Specificity | 2007 |
Tandem mass spectrometry analysis of N2-(trans-Isoestragol-3'-yl)-2'-deoxyguanosine as a strategy to study species differences in sulfotransferase conversion of the proximate carcinogen 1'-hydroxyestragole.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens; Chromatography, Liquid; Deoxyguanosine; Female; Humans; Kinetics; Liver; Male; Mice; Molecular Structure; Rats; Rats, Sprague-Dawley; Risk Factors; Safrole; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Subcellular Fractions; Sulfonic Acids; Sulfotransferases; Tandem Mass Spectrometry | 2007 |
A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat.
Topics: Allyl Compounds; Allylbenzene Derivatives; Animals; Anisoles; Carcinogens; Dose-Response Relationship, Drug; Female; Glucuronides; Inactivation, Metabolic; Kidney; Lung; Male; Models, Biological; Phenols; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfones; Tissue Distribution | 2008 |
Use of physiologically based biokinetic (PBBK) modeling to study estragole bioactivation and detoxification in humans as compared with male rats.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens; Female; Glucuronides; Humans; Inactivation, Metabolic; Intestine, Small; Kidney; Lung; Male; Microsomes, Liver; Models, Biological; Rats; Reproducibility of Results; Species Specificity; Toxicity Tests | 2009 |
Study of the metabolism of estragole in humans consuming fennel tea.
Topics: Adult; Allylbenzene Derivatives; Anisoles; Chromatography, High Pressure Liquid; Female; Foeniculum; Humans; Hydroxylation; Male; Phenol; Propanols; Tandem Mass Spectrometry | 2009 |
Evaluation of human interindividual variation in bioactivation of estragole using physiologically based biokinetic modeling.
Topics: Allylbenzene Derivatives; Anisoles; Carcinogens; Cytochrome P-450 Enzyme System; Flavoring Agents; Humans; Liver; Microsomes, Liver; Models, Chemical; Monte Carlo Method; Oxidation-Reduction | 2010 |
Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Flavones; Glucuronides; Hepatocytes; Humans; In Vitro Techniques; Male; Models, Biological; Ocimum basilicum; Oxidation-Reduction; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfotransferases; Toxicity Tests, Acute | 2010 |
In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.
Topics: Administration, Oral; Allylbenzene Derivatives; Animals; Anisoles; Chromatography, Liquid; DNA Adducts; Dose-Response Relationship, Drug; Glucuronides; Kidney; Liver; Lung; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2012 |
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Arylsulfotransferase; Carcinogens; Cell Line; Comet Assay; Dehydroepiandrosterone; DNA Damage; Gene Expression Regulation; Hepatocytes; Humans; Hymecromone; Liver; Pregnenolone; Rats; Sulfotransferases | 2016 |
Evaluation of Interindividual Human Variation in Bioactivation and DNA Adduct Formation of Estragole in Liver Predicted by Physiologically Based Kinetic/Dynamic and Monte Carlo Modeling.
Topics: Adolescent; Adult; Aged; Allylbenzene Derivatives; Anisoles; Carcinogens; Child, Preschool; Computer Simulation; DNA Adducts; Female; Humans; Infant; Kinetics; Liver; Male; Middle Aged; Models, Biological; Monte Carlo Method; NAD; Oxidation-Reduction; Sulfones; Young Adult | 2016 |
Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling.
Topics: Administration, Oral; Allylbenzene Derivatives; Anisoles; Arylsulfotransferase; Asian People; Carcinogens; Cytochrome P-450 Enzyme System; Humans; Inactivation, Metabolic; Microsomes, Liver; Models, Biological; White People | 2017 |
Cellular levels and molecular dynamics simulations of estragole DNA adducts point at inefficient repair resulting from limited distortion of the double-stranded DNA helix.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Carcinogens; Chromatography, Liquid; Cricetinae; Cricetulus; Deoxyguanosine; DNA; DNA Adducts; DNA Repair; Flavoring Agents; Hepatocytes; Mass Spectrometry; Molecular Dynamics Simulation; Rats; Toxicity Tests | 2020 |
In vitro and in silico study on consequences of combined exposure to the food-borne alkenylbenzenes estragole and safrole.
Topics: Allylbenzene Derivatives; Anisoles; Carcinogens; DNA Adducts; Hep G2 Cells; Humans; Risk Assessment; Safrole | 2022 |