estradiol-17 beta-glucuronide has been researched along with methotrexate in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 15 (68.18) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagenbuch, B; Meier, PJ; Noé, B; Stieger, B | 1 |
| Hirohashi, T; Sugiyama, Y; Suzuki, H | 1 |
| Kruh, GD; Liu, G; Rea, PA; Zeng, H | 1 |
| Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
| Chen, ZS; Kruh, GD; Lee, K | 1 |
| Abe, T; Inui, K; Masuda, S; Saito, H; Takeuchi, A | 1 |
| Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H | 1 |
| Cattori, V; Hagenbuch, B; Landmann, L; Meier, PJ; Meijer, DK; Stieger, B; van Montfoort, JE; Winterhalter, KH | 1 |
| Akita, H; Hirohashi, T; Sugiyama, Y; Suzuki, H; Takikawa, H | 1 |
| Bindels, RJM; Peters, JGP; Russel, FGM; Smeets, PHE; van Aubel, RAMH | 1 |
| Folkers, G; Hagenbuch, B; Klenk, U; Meier, PJ; Pizzagalli, F; Stieger, B | 1 |
| Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I | 1 |
| Sugimoto, Y; Sugiyama, Y; Suzuki, H; Suzuki, M | 1 |
| Bates, SE; Belinsky, MG; Chen, ZS; Kruh, GD; Ren, XQ; Robey, RW; Ross, DD; Shchaveleva, I; Sugimoto, Y | 1 |
| Horie, T; Ito, K; Li, T | 1 |
| Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
| Belinsky, MG; Chen, ZS; Guo, Y; Kotova, E; Kruh, GD | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fent, K; Popovic, M; Smital, T; Zaja, R | 1 |
1 review(s) available for estradiol-17 beta-glucuronide and methotrexate
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
21 other study(ies) available for estradiol-17 beta-glucuronide and methotrexate
| Article | Year |
|---|---|
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Brain; Cardiac Glycosides; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis | 1997 |
Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).
Topics: Animals; ATP-Binding Cassette Transporters; Cells, Cultured; Drug Resistance, Multiple; Glucuronates; Glutathione; HeLa Cells; Humans; Kinetics; LLC-PK1 Cells; Multidrug Resistance-Associated Proteins; Rats; Swine | 1999 |
Transport of amphipathic anions by human multidrug resistance protein 3.
Topics: Adenosine Triphosphate; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Carbon Radioisotopes; Carrier Proteins; Cell Line; Cell Membrane; Estradiol; Glutathione; Glycocholic Acid; Humans; Kidney; Kinetics; Leukotriene C4; Methotrexate; Multidrug Resistance-Associated Proteins; Osmosis; Substrate Specificity; Tritium | 2000 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine.
Topics: 3T3 Cells; Animals; Anion Transport Proteins; Antimetabolites, Antineoplastic; Baculoviridae; Biological Transport; Carrier Proteins; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Resistance; Estradiol; Immunoblotting; Insecta; Kinetics; Mercaptopurine; Mice; Models, Biological; Osmosis; Thioguanine; Time Factors; Transfection | 2001 |
Multispecific substrate recognition of kidney-specific organic anion transporters OAT-K1 and OAT-K2.
Topics: Animals; Carrier Proteins; Cattle; Cell Line; Cells, Cultured; Folic Acid Antagonists; Kidney; Kinetics; Membrane Proteins; Methotrexate; Multidrug Resistance-Associated Proteins; Oocytes; Organ Specificity; Organic Anion Transporters; Substrate Specificity; Transfection; Xenopus laevis | 2001 |
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.
Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium | 2001 |
Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.
Topics: Animals; Biological Transport; Female; Liver; Oocytes; Organic Anion Transporters, Sodium-Independent; Rats; Solute Carrier Organic Anion Transporter Family Member 1B3; Subcellular Fractions; Substrate Specificity; Tissue Distribution; Xenopus laevis | 2001 |
Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Baculoviridae; Biological Transport; Cell Line; Cell Membrane; Genetic Vectors; Glucuronides; Glutathione; Humans; Methotrexate; Rats; Substrate Specificity | 2002 |
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cyclic AMP; Cyclic GMP; Estradiol; Humans; Immunohistochemistry; Insecta; Kidney Tubules, Proximal; Methotrexate; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Rats; Tissue Distribution | 2002 |
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.
Topics: Amino Acid Sequence; Animals; Brain; CHO Cells; Chromosomes, Human, Pair 12; Cloning, Molecular; Cricetinae; Diiodothyronines; Estradiol; Estrone; Female; Humans; Leydig Cells; Male; Membrane Proteins; Molecular Sequence Data; Oocytes; Organ Specificity; Organic Anion Transporters; Sequence Homology, Amino Acid; Sulfobromophthalein; Testis; Thyroxine; Triiodothyronine; Xenopus | 2002 |
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection | 2003 |
ABCG2 transports sulfated conjugates of steroids and xenobiotics.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Dehydroepiandrosterone Sulfate; Drug Resistance, Neoplasm; Humans; Kinetics; Lymphoma; Mice; Neoplasm Proteins; Recombinant Proteins; Steroids; Sulfuric Acids; Transfection; Tumor Cells, Cultured; Xenobiotics | 2003 |
Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Estradiol; Humans; Indoles; Methotrexate; Mutation; Neoplasm Proteins; Polyglutamic Acid; Transfection | 2003 |
Transport of fluorescein methotrexate by multidrug resistance-associated protein 3 in IEC-6 cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Fluorescent Antibody Technique; Intestinal Mucosa; Methotrexate; Rats; Spodoptera | 2003 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger | 2004 |
Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).
Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Dose-Response Relationship, Drug; Estradiol; Humans; Leukotriene C4; LLC-PK1 Cells; Protein Transport; Swine | 2005 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins | 2013 |