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estradiol-17 beta-glucuronide and digoxin

estradiol-17 beta-glucuronide has been researched along with digoxin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's7 (53.85)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagenbuch, B; Meier, PJ; NoƩ, B; Stieger, B1
Fattinger, K; Hagenbuch, B; Huber, R; Ismair, MG; Kullak-Ublick, GA; Landmann, L; Meier, PJ; Pizzagalli, F; Stieger, B1
Abe, T; Endou, H; Kusuhara, H; Meier, PJ; Sekine, T; Shitara, Y; Sugiyama, D; Sugiyama, Y; Suzuki, H1
Cattori, V; Hagenbuch, B; Landmann, L; Meier, PJ; Meijer, DK; Stieger, B; van Montfoort, JE; Winterhalter, KH1
Adachi, Y; Sugiyama, Y; Suzuki, H1
Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y1
Hofmann, AF; Kim, RB; Meng, LJ; Pang, KS; Tirona, RG; Wang, P; Wolkoff, AW1
Folkers, G; Hagenbuch, B; Klenk, U; Meier, PJ; Pizzagalli, F; Stieger, B1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bi, YA; Chupka, J; Duignan, DB; Kimoto, E; Xiao, Y1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1

Reviews

1 review(s) available for estradiol-17 beta-glucuronide and digoxin

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

12 other study(ies) available for estradiol-17 beta-glucuronide and digoxin

ArticleYear
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Sep-16, Volume: 94, Issue:19

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Brain; Cardiac Glycosides; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis

1997
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver.
    Gastroenterology, 2001, Volume: 120, Issue:2

    Topics: Animals; Anion Transport Proteins; Anions; Antibodies; Arylsulfatases; Biological Transport; Blotting, Northern; Carrier Proteins; Coloring Agents; DNA, Complementary; Estrone; Gene Expression; Humans; Liver; Molecular Weight; Oocytes; Rabbits; RNA, Messenger; Steryl-Sulfatase; Sulfobromophthalein; Xenopus laevis

2001
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Animals; Anion Transport Proteins; Blood-Brain Barrier; Brain; Carrier Proteins; Digoxin; Enzyme Inhibitors; Estradiol; Glucuronates; Male; Microinjections; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Rats; Rats, Wistar; Taurocholic Acid

2001
Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 443, Issue:2

    Topics: Animals; Biological Transport; Female; Liver; Oocytes; Organic Anion Transporters, Sodium-Independent; Rats; Solute Carrier Organic Anion Transporter Family Member 1B3; Subcellular Fractions; Substrate Specificity; Tissue Distribution; Xenopus laevis

2001
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.
    Pharmaceutical research, 2001, Volume: 18, Issue:12

    Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection

2001
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
    Pharmaceutical research, 2002, Volume: 19, Issue:2

    Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine

2002
Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:5

    Topics: Animals; Anions; Cholagogues and Choleretics; Choline; Gene Expression; HeLa Cells; Hepatocytes; Humans; In Vitro Techniques; Indicators and Reagents; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Sulfates; Sulfobromophthalein; Taurolithocholic Acid; Temperature

2002
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:10

    Topics: Amino Acid Sequence; Animals; Brain; CHO Cells; Chromosomes, Human, Pair 12; Cloning, Molecular; Cricetinae; Diiodothyronines; Estradiol; Estrone; Female; Humans; Leydig Cells; Male; Membrane Proteins; Molecular Sequence Data; Oocytes; Organ Specificity; Organic Anion Transporters; Sequence Homology, Amino Acid; Sulfobromophthalein; Testis; Thyroxine; Triiodothyronine; Xenopus

2002
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Characterization of digoxin uptake in sandwich-cultured human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Transport; Cells, Cultured; Digoxin; HEK293 Cells; Hepatocytes; Humans; Liver; Membrane Transport Proteins; Oocytes; Organic Anion Transporters; Transfection; Xenopus laevis

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012